Motif ID: NFY{A,B,C}.p2

Z-value: 4.432


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409302330.621.0e-02Click!
NFYAchr6_+_411488690.467.4e-02Click!
NFYBchr12_-_103055924-0.322.2e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_19035792 7.398 NM_178526
 SLC25A42
solute carrier family 25, member 42
chr1_+_144149794 6.654 NM_006472
 TXNIP
thioredoxin interacting protein
chr17_+_54587641 6.486 NM_018304
 PRR11
proline rich 11
chr7_+_99974781 6.323 AGFG2
ArfGAP with FG repeats 2
chr7_+_99974720 6.095 NM_006076
 AGFG2
ArfGAP with FG repeats 2
chr17_-_54587581 5.904 NM_001100595
NM_182620
 SKA2

spindle and kinetochore associated complex subunit 2

chr17_+_54587882 5.445 PRR11
proline rich 11
chr17_-_77573974 5.196 NM_144998
 STRA13
stimulated by retinoic acid 13 homolog (mouse)
chr17_+_43374021 5.160 PNPO
pyridoxamine 5'-phosphate oxidase
chr17_+_43373887 5.042 NM_018129
 PNPO
pyridoxamine 5'-phosphate oxidase
chr22_+_36384647 4.991 NM_020315
 PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr16_-_2204776 4.985 NM_001042371
 PGP
phosphoglycolate phosphatase
chr12_-_120725210 4.502 LOC338799
hypothetical LOC338799
chr17_-_54587306 4.445 SKA2
spindle and kinetochore associated complex subunit 2
chr19_+_54160369 4.292 NM_000146
 FTL
ferritin, light polypeptide
chr9_-_139084833 4.239 NM_178448
 C9orf140
chromosome 9 open reading frame 140
chr14_-_22825148 4.127 NM_020834
 HOMEZ
homeobox and leucine zipper encoding
chr17_-_53950191 4.061 NM_004687
 MTMR4
myotubularin related protein 4
chr14_-_22825072 4.053 HOMEZ
homeobox and leucine zipper encoding
chr17_+_23670247 4.022 NM_014573
 TMEM97
transmembrane protein 97

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 105 entries
enrichment   p-value GO term description
5.90 2.50e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
5.47 5.31e-07 GO:0006695 cholesterol biosynthetic process
5.01 1.80e-02 GO:0008299 isoprenoid biosynthetic process
4.89 2.12e-06 GO:0016126 sterol biosynthetic process
4.85 7.61e-18 GO:0006334 nucleosome assembly
4.71 1.35e-17 GO:0031497 chromatin assembly
4.69 3.38e-19 GO:0065004 protein-DNA complex assembly
4.58 2.23e-17 GO:0034728 nucleosome organization
4.53 9.12e-19 GO:0071824 protein-DNA complex subunit organization
4.46 1.01e-02 GO:0031576 G2/M transition checkpoint
4.31 3.95e-19 GO:0006323 DNA packaging
4.30 1.61e-02 GO:0006271 DNA strand elongation involved in DNA replication
4.10 3.08e-18 GO:0006333 chromatin assembly or disassembly
4.01 2.73e-04 GO:0000819 sister chromatid segregation
4.01 3.78e-02 GO:0022616 DNA strand elongation
3.90 1.04e-17 GO:0071103 DNA conformation change
3.87 1.02e-08 GO:0000236 mitotic prometaphase
3.82 3.07e-03 GO:0000070 mitotic sister chromatid segregation
3.57 3.84e-09 GO:0007059 chromosome segregation
2.98 1.88e-17 GO:0000087 M phase of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 54 entries
enrichment   p-value GO term description
7.16 2.86e-05 GO:0042613 MHC class II protein complex
7.02 3.94e-03 GO:0008250 oligosaccharyltransferase complex
5.18 6.41e-14 GO:0000786 nucleosome
4.30 4.07e-02 GO:0000795 synaptonemal complex
4.14 2.26e-13 GO:0032993 protein-DNA complex
3.46 3.05e-04 GO:0000794 condensed nuclear chromosome
3.34 6.56e-06 GO:0000779 condensed chromosome, centromeric region
3.31 9.52e-20 GO:0000785 chromatin
3.30 3.16e-05 GO:0000777 condensed chromosome kinetochore
3.15 7.26e-10 GO:0000793 condensed chromosome
3.15 7.83e-06 GO:0000776 kinetochore
3.14 5.05e-04 GO:0000922 spindle pole
3.02 6.73e-09 GO:0000775 chromosome, centromeric region
3.01 2.01e-30 GO:0044427 chromosomal part
2.92 6.19e-34 GO:0005694 chromosome
2.83 5.56e-09 GO:0044454 nuclear chromosome part
2.58 1.59e-08 GO:0000228 nuclear chromosome
2.49 2.14e-06 GO:0005819 spindle
2.12 3.93e-05 GO:0005759 mitochondrial matrix
1.91 1.15e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
6.68 4.46e-02 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
2.20 6.33e-04 GO:0003682 chromatin binding
1.53 5.95e-05 GO:0030528 transcription regulator activity
1.50 1.06e-12 GO:0003677 DNA binding
1.44 1.13e-15 GO:0003676 nucleic acid binding
1.33 1.02e-02 GO:0005524 ATP binding
1.32 1.19e-02 GO:0030554 adenyl nucleotide binding
1.32 1.78e-02 GO:0032559 adenyl ribonucleotide binding
1.27 4.55e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.25 1.42e-02 GO:0000166 nucleotide binding
1.17 2.93e-07 GO:0005515 protein binding
1.15 4.88e-03 GO:0003824 catalytic activity
1.12 4.71e-12 GO:0005488 binding