Motif ID: NKX2-2,8.p2

Z-value: 1.598


Transcription factors associated with NKX2-2,8.p2:

Gene SymbolEntrez IDGene Name
NKX2-2 4821 NK2 homeobox 2
NKX2-8 26257 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-2chr20_-_21442663-0.312.5e-01Click!
NKX2-8chr14_-_36121536-0.029.5e-01Click!


Activity profile for motif NKX2-2,8.p2.

activity profile for motif NKX2-2,8.p2


Sorted Z-values histogram for motif NKX2-2,8.p2

Sorted Z-values for motif NKX2-2,8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2,8.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_40454188 4.731 ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_102320148 3.550 NM_003856
 IL1RL1
interleukin 1 receptor-like 1
chr3_-_122862391 3.455 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_122862447 3.414 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_-_101115677 2.448 NM_002674
 PMCH
pro-melanin-concentrating hormone
chr17_-_26665144 2.394 EVI2B
ecotropic viral integration site 2B
chr9_+_122923864 2.375 CEP110
centrosomal protein 110kDa
chr3_-_15814678 2.099 NM_001195098
 ANKRD28
ankyrin repeat domain 28
chrX_+_11687655 2.092 NM_006800
 MSL3
male-specific lethal 3 homolog (Drosophila)
chr13_+_110653407 1.873 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr12_-_9913199 1.820 CLEC2B
C-type lectin domain family 2, member B
chr13_-_40454360 1.817 NM_001145353
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_224993498 1.733 NM_002221
 ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr1_+_242281175 1.633 NM_205768
 ZNF238
zinc finger protein 238
chr9_+_115303527 1.614 NM_130795
 RGS3
regulator of G-protein signaling 3
chr17_-_26665194 1.513 EVI2B
ecotropic viral integration site 2B
chr17_-_26665213 1.489 EVI2B
ecotropic viral integration site 2B
chr17_-_26665220 1.489 NM_006495
 EVI2B
ecotropic viral integration site 2B
chr21_-_14840506 1.474 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_-_24590867 1.450 NM_173463
 CCDC149
coiled-coil domain containing 149

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.37 6.14e-03 GO:0007165 signal transduction
1.33 1.84e-02 GO:0023052 signaling
1.30 3.57e-02 GO:0051716 cellular response to stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.65 2.88e-02 GO:0030234 enzyme regulator activity