Motif ID: NKX3-1.p2

Z-value: 1.276


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23596346-0.097.3e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_132000134 3.181 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_61655915 2.183 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_-_53847937 1.898 RNF43
ring finger protein 43
chr3_-_198784590 1.452 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr4_+_74520796 1.230 NM_001134
AFP
alpha-fetoprotein
chr2_-_165259334 1.215 COBLL1
COBL-like 1
chr14_+_87541220 1.176 NM_003608
GPR65
G protein-coupled receptor 65
chr4_+_74491272 1.156 ALB
albumin
chr1_+_205329206 1.084 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta


chr3_+_173043832 1.058 NM_001164436
TMEM212
transmembrane protein 212
chr4_+_74488947 1.054 ALB
albumin
chr1_+_158975662 1.037 NM_021181
SLAMF7
SLAM family member 7
chr6_+_126282078 1.034 NCOA7
nuclear receptor coactivator 7
chr15_+_57691382 1.032 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_42892195 1.028 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr3_+_152970904 1.023 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr9_+_89302574 1.016 NM_004938
DAPK1
death-associated protein kinase 1
chr4_-_186969041 1.013 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr8_-_17797127 1.004 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr7_+_99654806 0.958 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.64 3.29e-21 GO:0007608 sensory perception of smell
3.42 1.79e-20 GO:0007606 sensory perception of chemical stimulus
2.30 1.21e-11 GO:0007600 sensory perception
1.79 1.38e-07 GO:0050877 neurological system process
1.69 1.89e-07 GO:0003008 system process
1.25 2.71e-05 GO:0050896 response to stimulus
1.24 3.43e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.46 1.67e-04 GO:0005576 extracellular region
1.40 9.19e-09 GO:0005886 plasma membrane
1.38 1.94e-08 GO:0071944 cell periphery
1.26 2.10e-05 GO:0031224 intrinsic to membrane
1.25 6.82e-05 GO:0016021 integral to membrane
1.23 1.42e-05 GO:0044425 membrane part
1.16 2.22e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.76 1.43e-22 GO:0004984 olfactory receptor activity
2.53 1.49e-17 GO:0004930 G-protein coupled receptor activity
2.03 2.96e-13 GO:0004888 transmembrane receptor activity
1.79 3.62e-11 GO:0004872 receptor activity
1.63 5.17e-09 GO:0004871 signal transducer activity
1.63 5.17e-09 GO:0060089 molecular transducer activity