Motif ID: NKX3-2.p2

Z-value: 2.301


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
NKX3-2 579 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-2chr4_-_13155135-0.504.8e-02Click!


Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_17585462 5.693 VSNL1
visinin-like 1
chr2_-_70634129 4.601 NM_001099691
NM_003236
 TGFA

transforming growth factor, alpha

chr2_+_17585287 3.673 NM_003385
 VSNL1
visinin-like 1
chr10_+_24795446 2.888 KIAA1217
KIAA1217
chr5_+_52812236 2.684 NM_006350
NM_013409
 FST

follistatin

chr10_+_24795465 2.671 KIAA1217
KIAA1217
chr5_+_56507029 2.576 NM_001127235
 GPBP1
GC-rich promoter binding protein 1
chr5_+_52812165 2.570 FST
follistatin
chr2_-_238861830 2.518 NM_022817
 PER2
period homolog 2 (Drosophila)
chr6_+_54819527 2.387 NM_001010872
 FAM83B
family with sequence similarity 83, member B
chr10_-_5035967 2.385 NM_001135241
 AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr6_-_41823056 2.286 NM_001166424
NM_002630
 PGC

progastricsin (pepsinogen C)

chrX_-_107568211 2.189 NM_033641
 COL4A6
collagen, type IV, alpha 6
chr8_+_120289735 2.184 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr11_-_119513429 2.178 TRIM29
tripartite motif containing 29
chr11_-_119499188 2.140 TRIM29
tripartite motif containing 29
chr16_+_55963899 2.059 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr16_+_55963883 2.015 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr20_+_51023159 1.958 TSHZ2
teashirt zinc finger homeobox 2
chr5_+_68746694 1.940 NM_001038603
 MARVELD2
MARVEL domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.30 1.17e-02 GO:0033036 macromolecule localization
1.27 1.89e-03 GO:0010467 gene expression
1.21 1.02e-02 GO:0044267 cellular protein metabolic process
1.20 2.60e-06 GO:0044260 cellular macromolecule metabolic process
1.17 2.12e-05 GO:0043170 macromolecule metabolic process
1.14 5.10e-05 GO:0044238 primary metabolic process
1.13 2.90e-04 GO:0044237 cellular metabolic process
1.12 7.27e-05 GO:0008152 metabolic process
1.09 1.96e-07 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.69 8.04e-04 GO:0034708 methyltransferase complex
2.69 8.04e-04 GO:0035097 histone methyltransferase complex
1.34 4.40e-02 GO:0044451 nucleoplasm part
1.31 4.81e-04 GO:0005654 nucleoplasm
1.29 4.75e-02 GO:0005794 Golgi apparatus
1.26 4.93e-04 GO:0031981 nuclear lumen
1.25 8.22e-05 GO:0070013 intracellular organelle lumen
1.24 1.38e-04 GO:0043233 organelle lumen
1.23 2.82e-04 GO:0031974 membrane-enclosed lumen
1.23 1.91e-03 GO:0005829 cytosol
1.22 2.42e-03 GO:0044428 nuclear part
1.19 3.34e-02 GO:0031090 organelle membrane
1.18 3.03e-04 GO:0032991 macromolecular complex
1.17 7.29e-08 GO:0044446 intracellular organelle part
1.17 6.70e-03 GO:0043234 protein complex
1.16 8.37e-08 GO:0044444 cytoplasmic part
1.16 2.90e-07 GO:0044422 organelle part
1.13 1.25e-09 GO:0005737 cytoplasm
1.12 7.70e-09 GO:0043231 intracellular membrane-bounded organelle
1.12 1.17e-08 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.32 4.65e-02 GO:0003723 RNA binding
1.14 2.97e-08 GO:0005515 protein binding
1.05 1.14e-02 GO:0005488 binding