Motif ID: NR3C1.p2

Z-value: 0.895


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_1427634180.562.4e-02Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_92670764 2.835 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_92671005 2.387 NM_014391
 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_-_56266408 1.479 LOC100129434
hypothetical LOC100129434
chr5_+_149867866 1.336 NM_001543
 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr14_+_99309688 1.324 EML1
echinoderm microtubule associated protein like 1
chr6_+_36752244 1.254 NM_078467
 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr4_+_2783743 1.240 NM_001145855
 SH3BP2
SH3-domain binding protein 2
chr18_-_51219880 0.931 TCF4
transcription factor 4
chr15_-_68781662 0.893 NM_001008224
 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr13_+_75092570 0.891 NM_005358
 LMO7
LIM domain 7
chr6_-_48186868 0.886 C6orf138
chromosome 6 open reading frame 138
chr3_-_150858274 0.879 NM_001168280
NM_015472
 WWTR1

WW domain containing transcription regulator 1

chr22_-_37480898 0.707 SUN2
Sad1 and UNC84 domain containing 2
chr11_-_8695974 0.679 ST5
suppression of tumorigenicity 5
chr1_+_160868932 0.663 DDR2
discoidin domain receptor tyrosine kinase 2
chr4_+_2783764 0.662 SH3BP2
SH3-domain binding protein 2
chr6_+_64289585 0.656 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr7_-_150576634 0.616 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr13_+_112825113 0.611 NM_000504
 F10
coagulation factor X
chr11_+_73036241 0.574 NM_001130034
NM_001130035
 PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.88 5.41e-07 GO:0007608 sensory perception of smell
2.69 1.91e-06 GO:0007606 sensory perception of chemical stimulus
1.99 6.92e-04 GO:0007600 sensory perception
1.97 3.77e-03 GO:0006955 immune response
1.75 1.96e-03 GO:0002376 immune system process
1.33 5.55e-06 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.87 1.78e-03 GO:0005615 extracellular space
1.65 1.76e-02 GO:0044421 extracellular region part
1.42 1.34e-06 GO:0005886 plasma membrane
1.42 1.71e-06 GO:0071944 cell periphery
1.30 2.13e-04 GO:0016021 integral to membrane
1.29 2.24e-04 GO:0031224 intrinsic to membrane
1.27 1.10e-04 GO:0044425 membrane part
1.21 8.74e-04 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
9.83 3.55e-02 GO:0004522 pancreatic ribonuclease activity
2.88 3.11e-07 GO:0004984 olfactory receptor activity
2.18 6.74e-07 GO:0004930 G-protein coupled receptor activity
1.86 1.76e-08 GO:0004872 receptor activity
1.85 9.16e-06 GO:0004888 transmembrane receptor activity
1.72 1.45e-07 GO:0004871 signal transducer activity
1.72 1.45e-07 GO:0060089 molecular transducer activity