Motif ID: NR5A1,2.p2

Z-value: 1.896


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR5A1chr9_-_1263095100.766.9e-04Click!
NR5A2chr1_+_1982633520.302.7e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_27113018 4.484 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr8_-_37576515 3.715 LOC157860
hypothetical protein LOC157860
chr2_+_219354948 2.570 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr12_-_120781002 2.530 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr5_+_176449156 2.378 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr22_+_19458378 2.347 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr16_-_28515868 2.100 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr11_-_16380967 2.076 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr17_+_1586034 2.041 WDR81
WD repeat domain 81
chr3_+_50281582 2.035 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr20_-_44713466 1.998 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr3_-_49435114 1.929 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr14_-_93829347 1.911 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_11211282 1.885 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr3_-_49701085 1.848 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_+_116238309 1.766 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr17_-_6557375 1.760 NM_001143838
NM_177550
SLC13A5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr10_+_60607232 1.662 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr19_-_17217022 1.645 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr3_+_186529376 1.642 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr5_-_42847716 1.639 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr1_-_159459814 1.636 APOA2
apolipoprotein A-II
chr11_+_22652957 1.626 GAS2
growth arrest-specific 2
chr2_+_119905812 1.624 NM_183240
TMEM37
transmembrane protein 37
chr16_-_16224791 1.610 NM_001079528
NM_001171
ABCC6

ATP-binding cassette, sub-family C (CFTR/MRP), member 6

chr10_-_21826192 1.584 C10orf114
chromosome 10 open reading frame 114
chr6_+_131190237 1.577 NM_001195597
LOC285733
hypothetical LOC285733
chr11_+_22652894 1.574 NM_005256
GAS2
growth arrest-specific 2
chr6_-_2785682 1.572 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr10_-_21826211 1.545 NM_001010911
C10orf114
chromosome 10 open reading frame 114
chr17_-_7023378 1.519 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr12_-_52975777 1.511 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr8_-_17812151 1.474


chr12_-_51585004 1.457 NM_002273
KRT8
keratin 8
chr7_+_94374862 1.448 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr2_-_88208650 1.417 NM_001443
FABP1
fatty acid binding protein 1, liver
chr16_+_70646008 1.398 NM_001126102
NM_005143
HP

haptoglobin

chr12_-_52975823 1.380 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr22_+_43451600 1.347 PRR5
proline rich 5 (renal)
chr18_-_28606839 1.340 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr10_-_91395194 1.327 NM_148977
PANK1
pantothenate kinase 1
chrX_-_24600661 1.308 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_159462456 1.307 NM_032174
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr7_-_100077072 1.291 NM_003227
TFR2
transferrin receptor 2
chr10_+_102722275 1.272 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr8_-_17811750 1.246 FGL1
fibrinogen-like 1
chr22_+_19239221 1.244 MED15
mediator complex subunit 15
chr11_-_5227611 1.238 NM_000559
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr20_+_48241334 1.229 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_54420574 1.218 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr12_-_9159780 1.175 A2M
alpha-2-macroglobulin
chr12_-_9159742 1.173 A2M
alpha-2-macroglobulin
chr12_-_9159707 1.168 A2M
alpha-2-macroglobulin
chr22_+_43451351 1.166 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr11_+_60858611 1.165 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr5_+_80564894 1.161 NM_001099735
NM_001099736
NM_001825
CKMT2


creatine kinase, mitochondrial 2 (sarcomeric)


chr9_-_129752687 1.158 NM_203305
FAM102A
family with sequence similarity 102, member A
chr7_+_29486010 1.151 NM_001039936
CHN2
chimerin (chimaerin) 2
chr12_+_54910767 1.137 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr12_+_100615530 1.135 NM_020244
CHPT1
choline phosphotransferase 1
chr12_-_23993830 1.135 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr2_+_138438277 1.134 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr12_-_9159789 1.130 NM_000014
A2M
alpha-2-macroglobulin
chr16_+_55963899 1.125 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr2_-_175754366 1.124 NM_001002258
NM_001190329
NM_001689
ATP5G3


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)


chr14_-_60185659 1.113 NM_005982
SIX1
SIX homeobox 1
chr17_-_7023283 1.098 ASGR1
asialoglycoprotein receptor 1
chr17_-_17426416 1.085 PEMT
phosphatidylethanolamine N-methyltransferase
chr16_+_28782682 1.082 NM_001145812
NM_015503
SH2B1

SH2B adaptor protein 1

chr17_+_24394281 1.081 PIPOX
pipecolic acid oxidase
chr2_-_238164042 1.049 RAB17
RAB17, member RAS oncogene family
chr1_-_205290921 1.042 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chrX_+_49718954 1.038 NM_000084
CLCN5
chloride channel 5
chr16_+_30903963 1.029 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr2_-_165259334 1.020 COBLL1
COBL-like 1
chr5_-_41249270 1.014 NM_000065
C6
complement component 6
chr17_+_77289704 1.012 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr10_-_91394881 1.010 PANK1
pantothenate kinase 1
chr11_+_116205830 1.009 NM_000040
APOC3
apolipoprotein C-III
chr5_+_176807931 1.007 NM_001174102
PRR7
proline rich 7 (synaptic)
chr3_+_50281309 1.005 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_-_4491024 1.005 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr12_-_9123126 1.001 A2M
alpha-2-macroglobulin
chr3_-_124821868 1.000 MYLK
myosin light chain kinase
chr19_-_4491078 0.999 LRG1
leucine-rich alpha-2-glycoprotein 1
chr17_-_34015631 0.994 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr22_-_29231597 0.987 NM_001161368
NM_174977
SEC14L4

SEC14-like 4 (S. cerevisiae)

chr2_-_200033445 0.983 SATB2
SATB homeobox 2
chr1_+_205328834 0.982 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr12_-_7935010 0.964 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr2_-_32344192 0.955 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr11_+_73037382 0.954 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_-_47638890 0.948 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr1_+_160306093 0.947 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr16_+_55963883 0.943 CX3CL1
chemokine (C-X3-C motif) ligand 1
chrX_-_39921525 0.937 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr16_+_28782578 0.935 NM_001145795
NM_001145796
NM_001145797
SH2B1


SH2B adaptor protein 1


chr5_+_154072654 0.931 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr13_-_51483473 0.931 NM_000053
NM_001005918
ATP7B

ATPase, Cu++ transporting, beta polypeptide

chr17_+_77289775 0.930 NM_012140
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_31731647 0.925 NM_019101
APOM
apolipoprotein M
chr7_-_86942910 0.924 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr17_+_38306339 0.922 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr14_-_30959487 0.920 HEATR5A
HEAT repeat containing 5A
chr10_+_685887 0.917 C10orf108
chromosome 10 open reading frame 108
chr19_-_5789740 0.915 FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr1_+_154605626 0.912 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr6_+_31731667 0.891 APOM
apolipoprotein M
chr6_+_43846735 0.890 VEGFA
vascular endothelial growth factor A
chr8_+_121892719 0.875


chr3_-_188492163 0.873 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr1_+_205329206 0.873 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta


chr6_+_43136159 0.870 NM_201522
KLC4
kinesin light chain 4
chr3_-_185578621 0.870 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr3_-_24511180 0.865 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr12_-_55042793 0.865 NM_001638
APOF
apolipoprotein F
chr8_-_145725197 0.863 NM_001001795
C8orf82
chromosome 8 open reading frame 82
chr8_-_145725289 0.862 C8orf82
chromosome 8 open reading frame 82
chr19_-_4486202 0.858 NM_001013706
PLIN5
perilipin 5
chr15_-_50375143 0.856 NM_018728
MYO5C
myosin VC
chr6_+_105511615 0.854 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr20_+_29656744 0.845 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr17_+_77289804 0.842 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr3_-_124822113 0.838 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr9_+_116131889 0.835 NM_000608
ORM2
orosomucoid 2
chr22_-_22440054 0.817 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr19_-_60664860 0.816 NM_001136201
NM_001136202
NM_024710
ISOC2


isochorismatase domain containing 2


chr17_-_38421363 0.815 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr19_-_7244876 0.810 NM_000208
NM_001079817
INSR

insulin receptor

chr2_+_219354692 0.809 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr5_-_74198370 0.805 NM_015566
FAM169A
family with sequence similarity 169, member A
chr17_+_3324096 0.802 NM_001128085
ASPA
aspartoacylase
chr6_+_28425666 0.800 NM_024493
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr6_-_43135092 0.799 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr1_-_158306570 0.793 NM_002241
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr7_+_149707338 0.792 NM_173680
ZNF775
zinc finger protein 775
chr1_-_2129031 0.791 NM_001146310
C1orf86
chromosome 1 open reading frame 86
chr3_+_134947940 0.782 TF
transferrin
chr16_-_51138306 0.778 NM_001080430
TOX3
TOX high mobility group box family member 3
chr17_-_17426469 0.777 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chr13_-_33148899 0.776 STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_56135353 0.774 NM_031479
INHBE
inhibin, beta E
chr3_+_134947788 0.773 TF
transferrin
chr3_+_52803823 0.769 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr2_+_63131466 0.768 NM_014562
OTX1
orthodenticle homeobox 1
chr19_-_47723183 0.766 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr1_-_12599934 0.766 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr8_-_17702991 0.765


chr1_+_20751518 0.760 NM_207334
FAM43B
family with sequence similarity 43, member B
chr3_-_127719283 0.759 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr17_-_1499849 0.757 NM_031430
RILP
Rab interacting lysosomal protein
chr17_-_53849888 0.755 RNF43
ring finger protein 43
chr13_+_99056887 0.749 NM_206808
CLYBL
citrate lyase beta like
chr20_+_54367389 0.747 NM_080821
C20orf108
chromosome 20 open reading frame 108
chr17_-_53849929 0.745 NM_017763
RNF43
ring finger protein 43
chrX_-_105169370 0.742 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_+_134947894 0.741 TF
transferrin
chr12_+_131577229 0.737 NM_001142641
FBRSL1
fibrosin-like 1
chr7_+_104959767 0.732 NM_021930
RINT1
RAD50 interactor 1
chr17_-_53847937 0.731 RNF43
ring finger protein 43
chr11_+_67534364 0.729 NM_000694
NM_001030010
ALDH3B1

aldehyde dehydrogenase 3 family, member B1

chr8_-_13178327 0.714


chr9_-_130912728 0.708 NM_000755
CRAT
carnitine O-acetyltransferase
chr20_+_275329 0.706 NM_024958
NRSN2
neurensin 2
chr8_+_30721208 0.705 NM_005671
UBXN8
UBX domain protein 8
chr2_-_75650355 0.704 NM_032181
FAM176A
family with sequence similarity 176, member A
chr8_-_13018123 0.703 NM_001164271
DLC1
deleted in liver cancer 1
chr11_+_67534371 0.700 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr20_+_41621119 0.698 SGK2
serum/glucocorticoid regulated kinase 2
chr7_+_96473225 0.694 NM_005222
DLX6
distal-less homeobox 6
chr4_+_74520796 0.690 NM_001134
AFP
alpha-fetoprotein
chr8_-_121893468 0.689 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_+_57691272 0.685 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_86426518 0.683 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr2_-_238164452 0.680 NM_022449
RAB17
RAB17, member RAS oncogene family
chr9_-_14900992 0.677 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr3_-_24511456 0.675 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr6_-_3401512 0.674 SLC22A23
solute carrier family 22, member 23
chr20_+_32755778 0.674 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr20_+_41621079 0.670 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_32114060 0.669 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr16_+_631902 0.662 FAM195A
family with sequence similarity 195, member A
chr17_+_44325127 0.657 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr20_-_47963682 0.656 NM_001135773
SPATA2
spermatogenesis associated 2
chr2_-_65512619 0.654 SPRED2
sprouty-related, EVH1 domain containing 2
chr16_+_631828 0.634 NM_138418
FAM195A
family with sequence similarity 195, member A
chr13_+_96726415 0.631 MBNL2
muscleblind-like 2 (Drosophila)
chr6_+_143423738 0.630 AIG1
androgen-induced 1
chr16_-_4605003 0.630 FAM100A
family with sequence similarity 100, member A
chr17_+_78286687 0.628 NM_022158
FN3K
fructosamine 3 kinase
chr17_+_1595012 0.627 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr17_+_52518098 0.626 AKAP1
A kinase (PRKA) anchor protein 1
chr6_+_24603145 0.623 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr6_+_27969181 0.623 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr6_+_143423656 0.623 NM_016108
AIG1
androgen-induced 1
chr16_+_20328355 0.622 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr16_+_82544327 0.621 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr20_-_22514092 0.621 NM_153675
FOXA2
forkhead box A2
chr3_-_49434874 0.620 AMT
aminomethyltransferase
chr6_+_20510019 0.616 NM_001949
E2F3
E2F transcription factor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.11 7.38e-08 GO:0022904 respiratory electron transport chain
2.59 5.91e-06 GO:0045333 cellular respiration
1.18 1.56e-05 GO:0032501 multicellular organismal process
2.01 2.21e-05 GO:0015980 energy derivation by oxidation of organic compounds
1.79 9.53e-05 GO:0006091 generation of precursor metabolites and energy
2.41 9.85e-05 GO:0022900 electron transport chain
1.24 5.30e-04 GO:0006810 transport
1.22 1.76e-03 GO:0051234 establishment of localization
1.07 6.80e-03 GO:0009987 cellular process
1.18 2.03e-02 GO:0051179 localization
1.57 3.37e-02 GO:0006066 alcohol metabolic process
1.38 4.70e-02 GO:0055114 oxidation-reduction process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.13 1.27e-09 GO:0005743 mitochondrial inner membrane
1.72 4.98e-09 GO:0044429 mitochondrial part
1.86 1.15e-08 GO:0005740 mitochondrial envelope
1.87 1.75e-08 GO:0031966 mitochondrial membrane
2.00 2.69e-08 GO:0019866 organelle inner membrane
1.46 4.17e-08 GO:0005739 mitochondrion
1.58 4.37e-06 GO:0031967 organelle envelope
1.56 7.80e-06 GO:0031975 envelope
1.15 3.28e-05 GO:0044444 cytoplasmic part
1.15 3.82e-05 GO:0044422 organelle part
2.35 1.01e-04 GO:0044455 mitochondrial membrane part
1.14 4.33e-04 GO:0044446 intracellular organelle part
1.10 8.56e-04 GO:0005737 cytoplasm
2.51 1.10e-02 GO:0070469 respiratory chain
2.02 2.06e-02 GO:0043292 contractile fiber
2.07 2.19e-02 GO:0044449 contractile fiber part
2.01 3.77e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 1.03e-04 GO:0005515 protein binding