Motif ID: PATZ1.p2

Z-value: 2.418


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300723290.524.0e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_34114924 8.379 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr17_+_34115383 4.023 NM_005937
 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_-_25328452 3.813 NM_153759
 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_63829616 3.666 NM_004451
 ESRRA
estrogen-related receptor alpha
chr1_-_32574185 3.614 NM_023009
 MARCKSL1
MARCKS-like 1
chr17_-_73636386 3.597 NM_001127198
 TMC6
transmembrane channel-like 6
chr17_-_73636362 3.502 TMC6
transmembrane channel-like 6
chr19_-_4017739 3.408 NM_015898
 ZBTB7A
zinc finger and BTB domain containing 7A
chr8_+_144706699 3.145 NM_001166237
 GSDMD
gasdermin D
chrX_+_138060 3.089 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr9_-_125732005 3.061 NM_020946
NM_024820
 DENND1A

DENN/MADD domain containing 1A

chrX_+_9392980 2.894 NM_005647
 TBL1X
transducin (beta)-like 1X-linked
chr1_+_3679168 2.799 NM_001163724
 LOC388588
hypothetical protein LOC388588
chr19_-_55524445 2.676 NM_004977
 KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_61344501 2.671 ZNF444
zinc finger protein 444
chr16_+_29725311 2.654 NM_001042539
NM_002383
 MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr16_+_87047159 2.616 ZFPM1
zinc finger protein, multitype 1
chr6_+_34313007 2.539 HMGA1
high mobility group AT-hook 1
chr12_+_100615530 2.484 NM_020244
 CHPT1
choline phosphotransferase 1
chr6_+_34312979 2.458 HMGA1
high mobility group AT-hook 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 102 entries
enrichment   p-value GO term description
1.74 1.70e-03 GO:0006338 chromatin remodeling
1.66 5.84e-09 GO:0016569 covalent chromatin modification
1.66 9.06e-09 GO:0016570 histone modification
1.59 2.32e-15 GO:0016568 chromatin modification
1.41 1.16e-08 GO:0006325 chromatin organization
1.41 6.53e-03 GO:0051259 protein oligomerization
1.38 2.38e-03 GO:0032446 protein modification by small protein conjugation
1.37 1.10e-02 GO:0016567 protein ubiquitination
1.34 1.27e-07 GO:0051276 chromosome organization
1.34 4.46e-06 GO:0051253 negative regulation of RNA metabolic process
1.34 5.35e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.34 4.10e-02 GO:0007346 regulation of mitotic cell cycle
1.33 1.88e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.33 3.05e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.33 8.70e-07 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 1.10e-02 GO:0070647 protein modification by small protein conjugation or removal
1.32 1.75e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 1.80e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.32 8.80e-03 GO:0010564 regulation of cell cycle process
1.31 7.93e-07 GO:0009890 negative regulation of biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
2.22 1.04e-02 GO:0031519 PcG protein complex
1.86 7.28e-03 GO:0000781 chromosome, telomeric region
1.75 4.10e-02 GO:0017053 transcriptional repressor complex
1.73 6.82e-05 GO:0000790 nuclear chromatin
1.68 1.03e-04 GO:0016585 chromatin remodeling complex
1.50 5.93e-05 GO:0044454 nuclear chromosome part
1.48 1.14e-05 GO:0000228 nuclear chromosome
1.38 1.90e-03 GO:0000785 chromatin
1.33 3.49e-02 GO:0016604 nuclear body
1.30 8.14e-08 GO:0044451 nucleoplasm part
1.30 1.10e-05 GO:0005694 chromosome
1.30 1.29e-04 GO:0044427 chromosomal part
1.27 8.88e-18 GO:0031981 nuclear lumen
1.27 5.99e-13 GO:0005654 nucleoplasm
1.26 1.53e-20 GO:0044428 nuclear part
1.23 4.28e-16 GO:0070013 intracellular organelle lumen
1.22 5.37e-16 GO:0043233 organelle lumen
1.21 7.32e-15 GO:0031974 membrane-enclosed lumen
1.19 1.44e-10 GO:0005829 cytosol
1.17 2.61e-29 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
1.67 5.43e-03 GO:0042393 histone binding
1.60 4.59e-02 GO:0047485 protein N-terminus binding
1.49 5.25e-05 GO:0010843 promoter binding
1.48 5.16e-05 GO:0000975 regulatory region DNA binding
1.48 5.16e-05 GO:0001067 regulatory region nucleic acid binding
1.48 5.16e-05 GO:0044212 transcription regulatory region DNA binding
1.41 1.12e-05 GO:0016564 transcription repressor activity
1.41 1.79e-05 GO:0008134 transcription factor binding
1.41 7.13e-03 GO:0003682 chromatin binding
1.39 6.33e-04 GO:0003702 RNA polymerase II transcription factor activity
1.37 1.32e-04 GO:0016563 transcription activator activity
1.35 1.85e-02 GO:0019787 small conjugating protein ligase activity
1.32 4.13e-09 GO:0019899 enzyme binding
1.30 2.57e-07 GO:0043565 sequence-specific DNA binding
1.28 2.80e-03 GO:0019904 protein domain specific binding
1.27 6.19e-09 GO:0030528 transcription regulator activity
1.27 2.91e-02 GO:0003712 transcription cofactor activity
1.27 3.59e-02 GO:0000988 protein binding transcription factor activity
1.27 3.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.26 9.06e-06 GO:0016301 kinase activity