Motif ID: PAX2.p2

Z-value: 1.927


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX2chr10_+_102495327-0.401.3e-01Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_113330574 2.671 NM_000192
NM_080717
TBX5

T-box 5

chr17_-_44022595 1.867 HOXB3
homeobox B3
chr5_+_60663842 1.561 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr17_+_14145051 1.511 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr6_-_33493640 1.462 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr8_-_13178399 1.393 DLC1
deleted in liver cancer 1
chr6_-_84994032 1.381 NM_014895
KIAA1009
KIAA1009
chr15_+_41597097 1.271 NM_002373
MAP1A
microtubule-associated protein 1A
chr6_-_33493792 1.195 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr6_-_33493898 1.180 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr8_-_13178327 1.175


chr15_-_71712711 1.152 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr1_-_184916044 1.151 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr13_-_32757835 1.144 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_+_25467948 1.134 NM_032141
CCDC55
coiled-coil domain containing 55
chr6_-_33494042 1.110 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr8_-_119192985 1.108 NM_000127
EXT1
exostosin 1
chr12_+_15926554 1.101 NM_007178
STRAP
serine/threonine kinase receptor associated protein
chr8_-_95343716 1.089 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr5_-_16795336 1.075 MYO10
myosin X

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.75 4.34e-03 GO:0006366 transcription from RNA polymerase II promoter
1.71 4.91e-03 GO:0071495 cellular response to endogenous stimulus
1.71 9.70e-03 GO:0032870 cellular response to hormone stimulus
1.59 1.13e-06 GO:0046907 intracellular transport
1.55 7.37e-03 GO:0034613 cellular protein localization
1.54 1.00e-02 GO:0070727 cellular macromolecule localization
1.46 2.89e-02 GO:0071310 cellular response to organic substance
1.45 2.51e-05 GO:0051649 establishment of localization in cell
1.42 8.20e-03 GO:0015031 protein transport
1.40 3.47e-05 GO:0033036 macromolecule localization
1.40 1.54e-02 GO:0045184 establishment of protein localization
1.39 1.94e-04 GO:0051641 cellular localization
1.37 9.09e-03 GO:0008104 protein localization
1.31 4.13e-04 GO:0010467 gene expression
1.29 3.55e-03 GO:0016070 RNA metabolic process
1.25 7.29e-03 GO:0090304 nucleic acid metabolic process
1.22 3.19e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 3.36e-02 GO:0048522 positive regulation of cellular process
1.20 1.52e-03 GO:0071840 cellular component organization or biogenesis
1.20 2.24e-03 GO:0016043 cellular component organization

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.17 4.20e-03 GO:0032991 macromolecular complex
1.16 1.47e-05 GO:0005634 nucleus
1.15 6.43e-05 GO:0044422 organelle part
1.15 7.61e-05 GO:0044446 intracellular organelle part
1.14 1.46e-04 GO:0044444 cytoplasmic part
1.13 6.37e-09 GO:0043231 intracellular membrane-bounded organelle
1.13 9.39e-09 GO:0043227 membrane-bounded organelle
1.13 4.78e-08 GO:0005737 cytoplasm
1.12 5.36e-09 GO:0043229 intracellular organelle
1.12 7.91e-09 GO:0043226 organelle
1.11 1.27e-12 GO:0044424 intracellular part
1.10 1.01e-11 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.54 3.19e-02 GO:0000988 protein binding transcription factor activity
1.54 3.19e-02 GO:0000989 transcription factor binding transcription factor activity
1.20 5.20e-15 GO:0005515 protein binding
1.08 3.82e-07 GO:0005488 binding