Motif ID: POU1F1.p2

Z-value: 1.235


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_87408301-0.136.3e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_105511615 1.610 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr5_-_78317444 1.549 NM_198709
 ARSB
arylsulfatase B
chr3_+_152970904 1.518 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr13_+_45174446 1.472 NM_152719
 SPERT
spermatid associated
chr2_-_88208650 1.461 NM_001443
 FABP1
fatty acid binding protein 1, liver
chr5_-_78318112 1.439 NM_000046
 ARSB
arylsulfatase B
chr8_-_17797127 1.363 NM_147203
NM_201553
NM_004467
NM_201552
 FGL1



fibrinogen-like 1



chr6_+_167456230 1.345 NM_031409
 CCR6
chemokine (C-C motif) receptor 6
chr21_+_41663853 1.237 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr12_-_101835183 1.215 PAH
phenylalanine hydroxylase
chr2_+_143351536 1.211 NM_001032998
NM_003937
 KYNU

kynureninase

chr1_+_149877955 1.193 SNX27
sorting nexin family member 27
chr12_-_49076658 1.157 NM_001145475
 FAM186A
family with sequence similarity 186, member A
chr11_+_59564323 1.115 NM_173801
 PLAC1L
placenta-specific 1-like
chr13_-_45654292 1.080 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_123779122 1.079 NM_001113523
 PARP15
poly (ADP-ribose) polymerase family, member 15
chr5_-_41249270 1.073 NM_000065
 C6
complement component 6
chr6_-_149847809 1.007 NM_207360
 ZC3H12D
zinc finger CCCH-type containing 12D
chr19_-_53081326 1.001 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr2_+_37282516 0.996 LOC100505876
hypothetical LOC100505876

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
9.86 7.27e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
3.59 3.54e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.53 8.78e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
3.50 3.74e-18 GO:0007606 sensory perception of chemical stimulus
3.48 8.54e-16 GO:0007608 sensory perception of smell
2.75 1.78e-03 GO:0002253 activation of immune response
2.75 1.63e-02 GO:0002764 immune response-regulating signaling pathway
2.70 3.56e-02 GO:0002757 immune response-activating signal transduction
2.62 3.72e-02 GO:0019221 cytokine-mediated signaling pathway
2.47 3.40e-03 GO:0050778 positive regulation of immune response
2.44 1.58e-05 GO:0050776 regulation of immune response
2.42 3.19e-04 GO:0045087 innate immune response
2.28 2.18e-08 GO:0006955 immune response
2.21 2.21e-08 GO:0007600 sensory perception
2.12 7.57e-07 GO:0006952 defense response
2.05 2.03e-02 GO:0002684 positive regulation of immune system process
1.82 4.91e-06 GO:0002376 immune system process
1.79 3.81e-02 GO:0002682 regulation of immune system process
1.76 1.12e-05 GO:0050877 neurological system process
1.65 1.89e-05 GO:0003008 system process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
11.97 1.61e-05 GO:0042613 MHC class II protein complex
5.89 3.39e-03 GO:0042611 MHC protein complex
1.43 3.98e-09 GO:0071944 cell periphery
1.43 6.82e-09 GO:0005886 plasma membrane
1.43 2.17e-03 GO:0005576 extracellular region
1.28 2.33e-05 GO:0031224 intrinsic to membrane
1.28 2.35e-05 GO:0016021 integral to membrane
1.24 6.04e-05 GO:0044425 membrane part
1.16 3.71e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.71 3.71e-02 GO:0003823 antigen binding
3.59 7.52e-17 GO:0004984 olfactory receptor activity
2.45 2.52e-13 GO:0004930 G-protein coupled receptor activity
2.14 9.39e-14 GO:0004888 transmembrane receptor activity
1.84 1.71e-10 GO:0004872 receptor activity
1.64 6.75e-08 GO:0004871 signal transducer activity
1.64 6.75e-08 GO:0060089 molecular transducer activity