Motif ID: POU2F1..3.p2

Z-value: 2.273


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F2chr19_-_473283990.783.9e-04Click!
POU2F1chr1_+_1655649040.757.5e-04Click!
POU2F3chr11_+_1196161120.292.8e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153098811 6.002 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801 5.567 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chrX_-_48661226 5.458 NM_006875
 PIM2
pim-2 oncogene
chr16_+_23754997 4.922 PRKCB
protein kinase C, beta
chr6_-_33016561 4.912 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_+_23754860 4.061 PRKCB
protein kinase C, beta
chr5_-_176868483 3.983 DOK3
docking protein 3
chr10_-_98021144 3.968 NM_001114094
NM_013314
 BLNK

B-cell linker

chr11_+_63829616 3.875 NM_004451
 ESRRA
estrogen-related receptor alpha
chr3_+_99733432 3.772 NM_005290
 GPR15
G protein-coupled receptor 15
chr1_+_165565006 3.743 POU2F1
POU class 2 homeobox 1
chr1_+_165564904 3.615 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr16_+_23754822 3.586 PRKCB
protein kinase C, beta
chr4_-_40212670 3.585 NM_019027
 RBM47
RNA binding motif protein 47
chr6_+_26325124 3.572 NM_021052
 HIST1H2AE
histone cluster 1, H2ae
chr1_+_226712430 3.463 NM_175055
 HIST3H2BB
histone cluster 3, H2bb
chr1_+_202000906 3.461 NM_001136190
NM_017773
 LAX1

lymphocyte transmembrane adaptor 1

chr1_-_226712140 3.375 NM_033445
 HIST3H2A
histone cluster 3, H2a
chr16_+_23754772 3.254 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr1_+_154386358 3.253 NM_001193301
 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
9.45 3.19e-14 GO:0006334 nucleosome assembly
8.97 1.19e-13 GO:0031497 chromatin assembly
8.89 3.37e-14 GO:0034728 nucleosome organization
8.56 9.00e-14 GO:0065004 protein-DNA complex assembly
8.43 3.19e-14 GO:0071824 protein-DNA complex subunit organization
7.67 2.51e-03 GO:0050909 sensory perception of taste
7.22 5.07e-13 GO:0006333 chromatin assembly or disassembly
6.87 7.42e-11 GO:0006323 DNA packaging
6.15 3.12e-10 GO:0071103 DNA conformation change
4.35 2.49e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.19 3.70e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.55 3.01e-07 GO:0034622 cellular macromolecular complex assembly
3.13 8.17e-07 GO:0006325 chromatin organization
3.10 2.78e-02 GO:0002253 activation of immune response
3.07 8.01e-07 GO:0034621 cellular macromolecular complex subunit organization
2.84 2.16e-02 GO:0050778 positive regulation of immune response
2.55 2.21e-06 GO:0006955 immune response
2.54 9.73e-05 GO:0051276 chromosome organization
2.30 9.03e-04 GO:0065003 macromolecular complex assembly
2.15 4.58e-03 GO:0071844 cellular component assembly at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
12.99 4.91e-17 GO:0000786 nucleosome
8.31 2.08e-12 GO:0032993 protein-DNA complex
5.03 6.89e-12 GO:0000785 chromatin
2.73 3.08e-05 GO:0044427 chromosomal part
2.57 2.50e-05 GO:0005694 chromosome
1.45 6.57e-03 GO:0043228 non-membrane-bounded organelle
1.45 6.57e-03 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
10.07 1.60e-06 GO:0003823 antigen binding
1.48 1.62e-02 GO:0003677 DNA binding