Motif ID: POU5F1.p2

Z-value: 1.354


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.731.3e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153098811 4.205 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_+_11246934 3.699 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr1_+_165564904 3.390 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr10_-_98021144 3.138 NM_001114094
NM_013314
 BLNK

B-cell linker

chr1_+_165565006 3.112 POU2F1
POU class 2 homeobox 1
chr5_-_88155360 2.877 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr7_-_76667045 2.611 NM_006682
 FGL2
fibrinogen-like 2
chr17_+_64922420 2.336 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr14_-_93512818 2.267 ASB2
ankyrin repeat and SOCS box containing 2
chr19_-_43800374 2.266 NM_001042600
NM_007181
 MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr15_-_78050515 2.035 NM_001114735
NM_004049
 BCL2A1

BCL2-related protein A1

chr14_-_93512647 1.911 ASB2
ankyrin repeat and SOCS box containing 2
chr5_+_140871107 1.878


chr12_+_91620749 1.876 NM_001037671
NM_001178097
 C12orf74

chromosome 12 open reading frame 74

chr5_-_124108672 1.780 NM_020747
 ZNF608
zinc finger protein 608
chr6_-_33016561 1.779 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr22_+_21393107 1.743 IGLJ3
immunoglobulin lambda joining 3
chr12_+_14409875 1.737 NM_018179
 ATF7IP
activating transcription factor 7 interacting protein
chr7_+_128795280 1.733 AHCYL2
adenosylhomocysteinase-like 2
chr3_+_99733432 1.693 NM_005290
 GPR15
G protein-coupled receptor 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
2.13 3.28e-03 GO:0045321 leukocyte activation
1.85 2.47e-04 GO:0001775 cell activation
1.82 2.90e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.77 4.69e-05 GO:0010628 positive regulation of gene expression
1.77 4.76e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.73 2.24e-04 GO:0051254 positive regulation of RNA metabolic process
1.70 8.28e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.70 1.26e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.69 3.88e-02 GO:0006325 chromatin organization
1.66 4.95e-02 GO:0007417 central nervous system development
1.65 2.58e-03 GO:0030182 neuron differentiation
1.65 2.09e-02 GO:0048666 neuron development
1.64 1.07e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 6.81e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.61 2.48e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.60 4.62e-03 GO:0006955 immune response
1.59 1.61e-03 GO:0009891 positive regulation of biosynthetic process
1.58 7.89e-04 GO:0022008 neurogenesis
1.56 3.25e-03 GO:0006351 transcription, DNA-dependent
1.56 3.64e-03 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.87 3.51e-02 GO:0000786 nucleosome
1.76 3.30e-03 GO:0043005 neuron projection
1.36 1.67e-02 GO:0005654 nucleoplasm
1.25 9.43e-09 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
4.44 1.94e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
4.44 1.94e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
1.76 1.98e-09 GO:0001071 nucleic acid binding transcription factor activity
1.76 1.98e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.75 7.63e-06 GO:0043565 sequence-specific DNA binding
1.68 1.23e-07 GO:0030528 transcription regulator activity
1.48 2.27e-10 GO:0003677 DNA binding
1.32 9.12e-07 GO:0003676 nucleic acid binding
1.12 2.79e-02 GO:0005515 protein binding
1.06 2.72e-02 GO:0005488 binding