Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.322


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_182912769-0.391.4e-01Click!
POU5F1chr6_-_312425930.391.4e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_27508139 3.497 LOC643401
hypothetical protein LOC643401
chr6_-_138862273 2.651


chr10_+_7785235 2.437 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr17_+_24394281 2.424 PIPOX
pipecolic acid oxidase
chr8_-_17797127 2.401 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr4_+_100714995 2.400 MTTP
microsomal triglyceride transfer protein
chr10_+_7785360 2.370 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 2.327 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 2.315 ITIH2
inter-alpha (globulin) inhibitor H2
chr17_+_24394043 2.232 NM_016518
PIPOX
pipecolic acid oxidase
chr2_+_128644510 2.210 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr4_+_74493918 2.205 ALB
albumin
chr21_+_41663853 1.933 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr4_+_74493174 1.852 ALB
albumin
chr3_+_186529376 1.824 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_+_3324096 1.762 NM_001128085
ASPA
aspartoacylase
chr6_+_24465109 1.669 NM_181337
KAAG1
kidney associated antigen 1
chr16_+_70646008 1.583 NM_001126102
NM_005143
HP

haptoglobin

chr4_+_74493331 1.542 ALB
albumin
chr12_-_14887648 1.529 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.55 3.14e-04 GO:0007608 sensory perception of smell
2.53 8.56e-05 GO:0007606 sensory perception of chemical stimulus
2.42 9.69e-03 GO:0045087 innate immune response
2.27 7.84e-06 GO:0006955 immune response
1.93 6.68e-03 GO:0006952 defense response
1.92 5.83e-03 GO:0007600 sensory perception
1.87 1.00e-04 GO:0002376 immune system process
1.68 8.69e-03 GO:0050877 neurological system process
1.29 4.08e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.35 3.33e-04 GO:0071944 cell periphery
1.35 4.53e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
5.40 3.72e-02 GO:0003823 antigen binding
2.61 6.68e-05 GO:0004984 olfactory receptor activity
2.06 3.65e-05 GO:0004930 G-protein coupled receptor activity
1.99 1.29e-07 GO:0004888 transmembrane receptor activity
1.77 2.00e-06 GO:0004872 receptor activity
1.70 8.61e-07 GO:0004871 signal transducer activity
1.70 8.61e-07 GO:0060089 molecular transducer activity