Motif ID: PRRX1,2.p2

Z-value: 3.009


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX2chr9_+_131467740-0.524.1e-02Click!
PRRX1chr1_+_168899936-0.097.3e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_104696678 5.997 NM_182691
 SRPK2
SRSF protein kinase 2
chrX_+_114734074 5.518 NM_001136025
NM_001172335
 PLS3

plastin 3

chr3_-_152517204 5.198 NM_023915
 GPR87
G protein-coupled receptor 87
chr15_+_91244563 5.186 CHD2
chromodomain helicase DNA binding protein 2
chr8_+_107807415 4.987 NM_001198534
NM_001198535
 OXR1

oxidation resistance 1

chr5_-_88155360 4.959 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr4_-_38710376 4.876 NM_024943
 TMEM156
transmembrane protein 156
chr4_-_153820535 4.709 NM_152680
 TMEM154
transmembrane protein 154
chr15_+_91244422 4.598 NM_001042572
NM_001271
 CHD2

chromodomain helicase DNA binding protein 2

chr8_-_17599438 4.573 NM_020749
 MTUS1
microtubule associated tumor suppressor 1
chr15_+_97990705 4.516 NM_001130928
 MEF2A
myocyte enhancer factor 2A
chr3_+_138132006 4.488 NM_001190796
 NCK1
NCK adaptor protein 1
chr4_-_152368492 4.287 SH3D19
SH3 domain containing 19
chr5_-_169340321 3.986 NM_001129891
 FAM196B
family with sequence similarity 196, member B
chr10_-_32707549 3.950 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr10_+_118177371 3.931 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr12_+_14429499 3.877 ATF7IP
activating transcription factor 7 interacting protein
chr10_-_95231933 3.755 NM_013451
NM_133337
 MYOF

myoferlin

chr22_-_34566367 3.753 NM_001031695
NM_001082576
NM_001082577
NM_014309
 RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr12_-_15005761 3.741 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.43 9.24e-03 GO:0006396 RNA processing
1.39 1.46e-02 GO:2000026 regulation of multicellular organismal development
1.33 1.03e-06 GO:0010467 gene expression
1.26 2.82e-03 GO:0016070 RNA metabolic process
1.23 3.82e-03 GO:0090304 nucleic acid metabolic process
1.15 3.24e-03 GO:0044260 cellular macromolecule metabolic process
1.14 5.02e-03 GO:0043170 macromolecule metabolic process
1.06 2.65e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.31 2.15e-04 GO:0005654 nucleoplasm
1.25 6.36e-04 GO:0031981 nuclear lumen
1.20 4.26e-03 GO:0031974 membrane-enclosed lumen
1.20 4.67e-03 GO:0043233 organelle lumen
1.20 6.12e-03 GO:0070013 intracellular organelle lumen
1.19 1.20e-02 GO:0044428 nuclear part
1.18 2.02e-03 GO:0043228 non-membrane-bounded organelle
1.18 2.02e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.13 1.07e-04 GO:0044446 intracellular organelle part
1.13 1.93e-04 GO:0044422 organelle part
1.10 6.16e-05 GO:0005737 cytoplasm
1.10 2.95e-02 GO:0005634 nucleus
1.08 3.97e-08 GO:0005622 intracellular
1.08 2.99e-04 GO:0043229 intracellular organelle
1.08 3.52e-04 GO:0043226 organelle
1.08 3.42e-03 GO:0043231 intracellular membrane-bounded organelle
1.08 3.81e-03 GO:0043227 membrane-bounded organelle
1.07 4.32e-06 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.11 5.79e-05 GO:0005515 protein binding