Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 9.208


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX2chr19_-_60614910.702.4e-03Click!
RFXANKchr19_+_19164732-0.665.6e-03Click!
RFX4chr12_+_1055008140.467.1e-02Click!
RFX3chr9_-_35157210.421.0e-01Click!
RFXAPchr13_+_36291306-0.411.1e-01Click!
RFX1chr19_-_139780960.401.2e-01Click!
RFX5chr1_-_149586298-0.136.3e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_42701460 17.451 CCDC30
coiled-coil domain containing 30
chr11_+_102485293 16.053 NM_001080463
NM_001377
 DYNC2H1

dynein, cytoplasmic 2, heavy chain 1

chr22_+_21817512 15.990 NM_004914
 RAB36
RAB36, member RAS oncogene family
chr5_-_14064846 15.134 DNAH5
dynein, axonemal, heavy chain 5
chr2_+_27046952 14.011 NM_012326
 MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr14_+_105012106 13.893 NM_001312
 CRIP2
cysteine-rich protein 2
chr2_-_187422141 13.275 NM_182521
 ZSWIM2
zinc finger, SWIM-type containing 2
chr15_+_68971835 12.773 NM_001199017
NM_017691
NM_001199018
 LRRC49


leucine rich repeat containing 49


chr2_+_74502364 12.607 NM_032118
 WDR54
WD repeat domain 54
chr18_+_30544193 11.950 NM_001198941
NM_032978
 DTNA

dystrobrevin, alpha

chr15_-_68971665 11.838 NM_020147
 THAP10
THAP domain containing 10
chr4_+_87734489 11.822 NM_006264
NM_080683
NM_080684
NM_080685
 PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr11_-_65860450 11.463 NM_004292
 RIN1
Ras and Rab interactor 1
chr4_-_177353707 9.440 NM_144644
 SPATA4
spermatogenesis associated 4
chr17_-_61618276 9.386 NM_145036
 CCDC46
coiled-coil domain containing 46
chr19_-_63776547 9.369 MZF1
myeloid zinc finger 1
chr3_-_139315011 9.223 NM_001170538
 DZIP1L
DAZ interacting protein 1-like
chr22_+_29393914 9.180


chr14_-_101841222 8.896 NM_014226
 RAGE
renal tumor antigen
chr6_+_109276280 8.880 NM_032131
 ARMC2
armadillo repeat containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
8.46 3.99e-07 GO:0042384 cilium assembly
6.40 8.28e-06 GO:0060271 cilium morphogenesis
5.00 2.96e-06 GO:0030031 cell projection assembly
4.66 8.25e-04 GO:0010927 cellular component assembly involved in morphogenesis
3.66 1.44e-03 GO:0007018 microtubule-based movement
2.90 3.98e-05 GO:0007017 microtubule-based process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
10.04 4.22e-03 GO:0060170 cilium membrane
7.91 1.56e-08 GO:0005932 microtubule basal body
6.92 1.93e-06 GO:0035085 cilium axoneme
6.49 3.91e-09 GO:0044441 cilium part
6.42 5.20e-08 GO:0005930 axoneme
4.82 3.23e-13 GO:0005929 cilium
2.99 3.59e-07 GO:0005874 microtubule
2.59 2.09e-05 GO:0005815 microtubule organizing center
2.56 3.99e-03 GO:0005813 centrosome
2.49 1.30e-10 GO:0015630 microtubule cytoskeleton
2.21 8.41e-04 GO:0044463 cell projection part
1.77 1.10e-04 GO:0044430 cytoskeletal part
1.71 3.11e-06 GO:0005856 cytoskeleton
1.41 5.80e-04 GO:0043228 non-membrane-bounded organelle
1.41 5.80e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.23 6.23e-07 GO:0005737 cytoplasm
1.22 1.35e-02 GO:0044422 organelle part
1.21 2.08e-02 GO:0044446 intracellular organelle part
1.13 3.20e-04 GO:0044424 intracellular part
1.12 5.01e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.77 6.34e-05 GO:0003777 microtubule motor activity
3.11 2.61e-03 GO:0003774 motor activity
1.44 1.42e-02 GO:0017076 purine nucleotide binding
1.42 2.73e-02 GO:0032553 ribonucleotide binding
1.42 2.73e-02 GO:0032555 purine ribonucleotide binding
1.36 4.84e-02 GO:0000166 nucleotide binding