Motif ID: RXRG_dimer.p3

Z-value: 1.414


Transcription factors associated with RXRG_dimer.p3:

Gene SymbolEntrez IDGene Name
NR1H2 7376 nuclear receptor subfamily 1, group H, member 2
PPARA 5465 peroxisome proliferator-activated receptor alpha
PPARG 5468 peroxisome proliferator-activated receptor gamma
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_123053360.861.8e-05Click!
RXRBchr6_-_332764260.371.6e-01Click!
NR1H2chr19_+_55571493-0.371.6e-01Click!
RXRAchr9_+_1363581450.312.5e-01Click!
PPARAchr22_+_449251620.302.6e-01Click!
RXRGchr1_-_1636809410.058.6e-01Click!


Activity profile for motif RXRG_dimer.p3.

activity profile for motif RXRG_dimer.p3


Sorted Z-values histogram for motif RXRG_dimer.p3

Sorted Z-values for motif RXRG_dimer.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRG_dimer.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_116205830 5.022 NM_000040
APOC3
apolipoprotein C-III
chr11_-_116213511 3.155 NM_000039
APOA1
apolipoprotein A-I
chr16_-_86527608 2.788 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr2_+_138438277 2.747 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr16_+_4654710 2.728 MGRN1
mahogunin, ring finger 1
chr7_-_100630912 2.660 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr5_+_92944680 2.628 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr20_+_55569542 2.548 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr12_+_54910767 2.524 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr2_+_73294852 2.242 NM_006062
SMYD5
SMYD family member 5
chr10_+_102722275 2.205 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_+_218992053 2.138 NM_007127
VIL1
villin 1
chr6_+_31731667 2.137 APOM
apolipoprotein M
chr6_+_31731647 2.136 NM_019101
APOM
apolipoprotein M
chr20_+_41621079 2.119 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr20_+_41621119 2.018 SGK2
serum/glucocorticoid regulated kinase 2
chr5_-_42847716 2.000 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr12_+_119900677 1.950 HNF1A
HNF1 homeobox A
chr10_-_52315390 1.793 A1CF
APOBEC1 complementation factor
chr2_+_161725172 1.744 TANK
TRAF family member-associated NFKB activator

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
29.72 6.67e-03 GO:0034377 plasma lipoprotein particle assembly
29.72 6.67e-03 GO:0065005 protein-lipid complex assembly
22.29 2.15e-03 GO:0048199 vesicle targeting, to, from or within Golgi
20.98 3.07e-02 GO:0043691 reverse cholesterol transport
14.86 1.80e-02 GO:0006903 vesicle targeting
9.60 7.61e-03 GO:0031647 regulation of protein stability
6.08 1.71e-02 GO:0048193 Golgi vesicle transport
1.45 1.59e-02 GO:0044237 cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
33.43 1.24e-02 GO:0034366 spherical high-density lipoprotein particle
3.91 2.15e-02 GO:0005759 mitochondrial matrix
2.63 2.09e-02 GO:0044429 mitochondrial part
1.38 3.65e-02 GO:0044444 cytoplasmic part
1.27 4.00e-02 GO:0043231 intracellular membrane-bounded organelle
1.27 4.22e-02 GO:0043227 membrane-bounded organelle

Nothing significant found in function category.