Motif ID: SPI1.p2

Z-value: 4.009


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566500.638.6e-03Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_35586950 10.552 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr6_-_32268267 6.105 GPSM3
G-protein signaling modulator 3
chr10_+_49562866 5.709 WDFY4
WDFY family member 4
chr5_-_88215034 5.671 NM_001193350
NM_002397
 MEF2C

myocyte enhancer factor 2C

chr16_-_87570716 5.598 NM_005187
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr3_-_113334657 5.478 NM_001190259
NM_001190260
NM_152785
 GCET2


germinal center expressed transcript 2


chr11_+_63864263 5.448 NM_032251
 CCDC88B
coiled-coil domain containing 88B
chr6_-_32268615 4.813 GPSM3
G-protein signaling modulator 3
chr16_-_29664765 4.632 NM_175900
 C16orf54
chromosome 16 open reading frame 54
chr21_+_25856311 4.617 MIR155HG
MIR155 host gene (non-protein coding)
chr1_+_159899528 4.613 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
 FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr5_+_118719591 4.595 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr11_+_65164767 4.476 SIPA1
signal-induced proliferation-associated 1
chr5_-_88214720 4.325 MEF2C
myocyte enhancer factor 2C
chr6_-_33016561 4.316 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_111544469 4.273


chr19_-_7672978 4.223 NM_002002
 FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr19_-_55091942 4.097 NM_152899
 IL4I1
interleukin 4 induced 1
chr11_+_66927976 4.093 NM_198517
 TBC1D10C
TBC1 domain family, member 10C
chr10_+_26767698 3.970 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 106 entries
enrichment   p-value GO term description
2.80 2.98e-02 GO:0050853 B cell receptor signaling pathway
1.95 2.82e-04 GO:0050851 antigen receptor-mediated signaling pathway
1.87 2.08e-03 GO:0030098 lymphocyte differentiation
1.79 8.29e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.77 3.19e-03 GO:0042110 T cell activation
1.72 3.51e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.71 3.53e-07 GO:0045321 leukocyte activation
1.71 3.15e-05 GO:0046649 lymphocyte activation
1.68 3.47e-04 GO:0002757 immune response-activating signal transduction
1.66 3.81e-02 GO:0002521 leukocyte differentiation
1.64 1.19e-03 GO:0002764 immune response-regulating signaling pathway
1.62 5.78e-03 GO:0051251 positive regulation of lymphocyte activation
1.59 9.01e-04 GO:0051249 regulation of lymphocyte activation
1.58 2.17e-02 GO:0050863 regulation of T cell activation
1.57 1.63e-03 GO:0071156 regulation of cell cycle arrest
1.57 3.75e-03 GO:0000075 cell cycle checkpoint
1.55 3.45e-02 GO:0050867 positive regulation of cell activation
1.54 7.32e-09 GO:0001775 cell activation
1.53 5.34e-03 GO:0002694 regulation of leukocyte activation
1.51 6.29e-05 GO:0006917 induction of apoptosis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
1.96 1.30e-02 GO:0016605 PML body
1.83 3.87e-02 GO:0030117 membrane coat
1.83 3.87e-02 GO:0048475 coated membrane
1.60 5.20e-05 GO:0016604 nuclear body
1.47 1.66e-08 GO:0005694 chromosome
1.45 1.67e-02 GO:0000785 chromatin
1.40 1.06e-04 GO:0044427 chromosomal part
1.38 1.78e-14 GO:0005654 nucleoplasm
1.38 3.32e-07 GO:0044451 nucleoplasm part
1.28 2.31e-11 GO:0031981 nuclear lumen
1.27 3.43e-12 GO:0044428 nuclear part
1.24 2.62e-09 GO:0005829 cytosol
1.21 1.97e-07 GO:0043233 organelle lumen
1.20 2.46e-07 GO:0031974 membrane-enclosed lumen
1.20 7.22e-07 GO:0070013 intracellular organelle lumen
1.16 3.75e-15 GO:0005634 nucleus
1.14 2.60e-05 GO:0032991 macromolecular complex
1.13 1.54e-03 GO:0043234 protein complex
1.13 4.18e-03 GO:0043228 non-membrane-bounded organelle
1.13 4.18e-03 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.85 1.88e-02 GO:0047485 protein N-terminus binding
1.56 4.84e-02 GO:0003714 transcription corepressor activity
1.54 3.67e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.53 4.94e-04 GO:0005096 GTPase activator activity
1.47 7.53e-07 GO:0060589 nucleoside-triphosphatase regulator activity
1.46 2.38e-06 GO:0030695 GTPase regulator activity
1.42 8.17e-03 GO:0016564 transcription repressor activity
1.42 1.38e-02 GO:0005083 small GTPase regulator activity
1.41 7.34e-04 GO:0008047 enzyme activator activity
1.39 3.63e-03 GO:0000988 protein binding transcription factor activity
1.39 3.63e-03 GO:0000989 transcription factor binding transcription factor activity
1.39 5.14e-03 GO:0003712 transcription cofactor activity
1.29 1.15e-03 GO:0019899 enzyme binding
1.28 1.03e-02 GO:0043565 sequence-specific DNA binding
1.27 5.00e-04 GO:0030234 enzyme regulator activity
1.24 1.82e-03 GO:0030528 transcription regulator activity
1.18 2.88e-30 GO:0005515 protein binding
1.15 4.13e-03 GO:0003677 DNA binding
1.12 7.85e-03 GO:0003676 nucleic acid binding
1.06 1.00e-09 GO:0005488 binding