Motif ID: SPIB.p2

Z-value: 4.429


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_556140060.811.2e-04Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_15005761 10.878 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_44643067 8.063 ABI3
ABI family, member 3
chr6_-_32268267 7.920 GPSM3
G-protein signaling modulator 3
chr17_-_40843530 7.878 ARHGAP27
Rho GTPase activating protein 27
chr19_-_40925151 6.974 NM_024660
TMEM149
transmembrane protein 149
chr2_-_225519974 6.118 DOCK10
dedicator of cytokinesis 10
chr7_+_128367961 5.943 NM_001098627
IRF5
interferon regulatory factor 5
chr2_-_175207521 5.743 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_11490487 5.496 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_+_63864263 5.404 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr14_+_99601498 5.362 NM_016337
EVL
Enah/Vasp-like
chr14_+_99601517 5.316 EVL
Enah/Vasp-like
chr6_-_32742265 5.312 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr17_-_44642934 5.215 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_-_32268615 5.205 GPSM3
G-protein signaling modulator 3
chr18_-_65766068 4.955 CD226
CD226 molecule
chr3_-_113701073 4.916 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr6_-_56824672 4.911 DST
dystonin
chr19_+_3129735 4.564 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr17_-_18890963 4.532 NM_006613
GRAP
GRB2-related adaptor protein
chr1_-_205161821 4.524 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chrX_+_48427137 4.482 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr16_+_28413421 4.369 NM_018690
APOBR
apolipoprotein B receptor
chr16_+_30102426 4.259 CORO1A
coronin, actin binding protein, 1A
chr5_+_61910318 4.232 NM_181506
LRRC70
leucine rich repeat containing 70
chrX_+_48427103 4.222 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr4_+_39874921 4.187 NM_004310
RHOH
ras homolog gene family, member H
chr19_-_6432765 4.144 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr6_+_31662454 4.142 NM_205837
LST1
leukocyte specific transcript 1
chr2_-_96174865 4.079 NM_004418
DUSP2
dual specificity phosphatase 2
chr17_+_73638430 4.058 NM_152468
TMC8
transmembrane channel-like 8
chr6_+_31661934 4.050 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr21_-_38792173 4.000 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr11_-_60880799 3.838 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr17_+_37693090 3.833 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr4_-_105631915 3.758 NM_025212
CXXC4
CXXC finger protein 4
chr7_+_149778815 3.746 GIMAP8
GTPase, IMAP family member 8
chr6_-_159386007 3.735 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr1_-_25128951 3.715 RUNX3
runt-related transcription factor 3
chr7_+_139175420 3.682 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr12_-_56157898 3.649 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr3_-_122862447 3.606 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_-_56824371 3.590 DST
dystonin
chr11_+_5602782 3.546 NM_021616
TRIM34
tripartite motif containing 34
chr18_-_59137488 3.526 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr3_-_122862391 3.491 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_+_233633348 3.488 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr3_-_120761092 3.481 NM_005191
CD80
CD80 molecule
chrX_-_100527799 3.471 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr2_+_233633279 3.445 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr9_-_129580732 3.395 NM_170600
SH2D3C
SH2 domain containing 3C
chr1_-_154727014 3.381 MEF2D
myocyte enhancer factor 2D
chr12_+_48443232 3.338 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr7_+_149778869 3.334 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr4_+_91035025 3.329 NM_007351
MMRN1
multimerin 1
chr14_+_87541220 3.317 NM_003608
GPR65
G protein-coupled receptor 65
chr11_+_120966280 3.314 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_25164061 3.309 NM_001031680
RUNX3
runt-related transcription factor 3
chr12_+_25096472 3.279 NM_006152
LRMP
lymphoid-restricted membrane protein
chr13_+_110653407 3.240 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_207995999 3.193 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr17_+_7180571 3.176 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_-_181826086 3.156 NCF2
neutrophil cytosolic factor 2
chrX_-_70248022 3.139 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr15_+_79376295 3.101 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr7_+_150013716 3.071 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr8_+_11388918 3.064 NM_001715
BLK
B lymphoid tyrosine kinase
chr5_+_168996852 2.991 DOCK2
dedicator of cytokinesis 2
chr17_+_44642587 2.974 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_-_181826633 2.959 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr10_+_70517863 2.958 SRGN
serglycin
chr11_-_66961709 2.950 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr6_-_25044156 2.949 FAM65B
family with sequence similarity 65, member B
chr10_+_70517823 2.944 NM_002727
SRGN
serglycin
chr19_+_14554895 2.925 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr12_+_25096755 2.910 LRMP
lymphoid-restricted membrane protein
chr7_+_149779011 2.908 GIMAP8
GTPase, IMAP family member 8
chr5_-_71838875 2.894 NM_152625
ZNF366
zinc finger protein 366
chr6_+_31690957 2.893 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr13_-_32678142 2.888 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr22_+_35586950 2.876 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr12_+_4253143 2.828 NM_001759
CCND2
cyclin D2
chr9_+_263025 2.821 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr1_-_158759606 2.792 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr5_-_176869148 2.774


chr3_+_195889845 2.750 FAM43A
family with sequence similarity 43, member A
chr12_+_91620749 2.750 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr19_+_10242516 2.739 NM_000201
ICAM1
intercellular adhesion molecule 1
chr6_+_31647854 2.694 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_-_120725210 2.680 LOC338799
hypothetical LOC338799
chr1_-_181826292 2.677 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr16_-_3567354 2.653 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr1_+_202000906 2.648 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr11_+_65164167 2.639 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr1_+_154390939 2.626 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_+_31455332 2.616 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr11_+_59979857 2.613 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr2_+_96355661 2.556 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr19_-_56567602 2.530 NM_005601
NKG7
natural killer cell group 7 sequence
chr11_-_60475558 2.529 NM_016582
SLC15A3
solute carrier family 15, member 3
chr5_-_138822475 2.513 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr6_-_27949266 2.500 NM_003546
HIST1H4L
histone cluster 1, H4l
chr1_+_27972269 2.496 NM_177424
STX12
syntaxin 12
chr5_-_169657192 2.495 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_176869463 2.482 NM_024872
DOK3
docking protein 3
chr6_+_31651319 2.447 NM_000594
TNF
tumor necrosis factor
chr5_-_169657395 2.447 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_+_126094067 2.445 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr5_-_169657312 2.439 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr18_-_59137948 2.423 BCL2
B-cell CLL/lymphoma 2
chr16_+_29581783 2.391 NM_001030288
SPN
sialophorin
chr5_-_176869440 2.390 DOK3
docking protein 3
chr4_-_25473528 2.390 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_+_9634368 2.383 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr17_+_73676219 2.363 NM_004710
SYNGR2
synaptogyrin 2
chr4_-_10295412 2.352 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr17_-_24491521 2.333 MYO18A
myosin XVIIIA
chr19_+_54530458 2.295 CD37
CD37 molecule
chr1_+_84540921 2.290 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr12_+_6930815 2.286 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_-_56159631 2.278 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr5_-_169657360 2.259 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_54530485 2.240 NM_001040031
NM_001774
CD37

CD37 molecule

chr3_+_120799411 2.239 NM_015900
PLA1A
phospholipase A1 member A
chr18_-_59138192 2.211 BCL2
B-cell CLL/lymphoma 2
chr19_+_54530512 2.205 CD37
CD37 molecule
chr12_+_6930778 2.202 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr16_-_30301357 2.197 SEPT1
septin 1
chr19_+_54530497 2.185 CD37
CD37 molecule
chr1_+_242281199 2.173 ZNF238
zinc finger protein 238
chr17_-_26672757 2.155 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr12_+_6930799 2.150 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr7_+_87401368 2.149 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr12_-_122486920 2.146 RILPL2
Rab interacting lysosomal protein-like 2
chr1_+_159943385 2.142 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr12_+_6930792 2.116 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_48443588 2.113 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr12_+_6930804 2.103 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_-_98470164 2.093 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr5_+_75734759 2.091 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_+_54530546 2.075 CD37
CD37 molecule
chr5_+_118719591 2.074 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_73145481 2.055 LIMK1
LIM domain kinase 1
chr10_+_26767268 2.055 NM_019043
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_26767288 2.049 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_+_218790364 2.034 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr15_+_38849450 2.030 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr10_+_35524835 2.030 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr2_-_213723298 2.025 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_-_53764867 2.022


chr6_-_33085329 2.022 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr9_+_126094388 2.019 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr12_+_6930734 2.015 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_9713472 1.999 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr1_+_242281175 1.998 NM_205768
ZNF238
zinc finger protein 238
chr12_-_122487172 1.993 NM_145058
RILPL2
Rab interacting lysosomal protein-like 2
chr1_+_149877955 1.992 SNX27
sorting nexin family member 27
chr6_-_33085290 1.988 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr3_+_120495906 1.986 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr12_+_55018925 1.981 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr16_-_49272741 1.979 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr1_+_165865953 1.964 NM_052862
RCSD1
RCSD domain containing 1
chr9_+_92629525 1.962 NM_001174167
SYK
spleen tyrosine kinase
chr17_-_5078773 1.954 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr16_+_29582065 1.954 SPN
sialophorin
chr2_-_197883739 1.934 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr10_-_53129315 1.927 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr16_+_29582069 1.926 NM_003123
SPN
sialophorin
chr12_+_6930694 1.922 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr12_+_45896511 1.920 FAM113B
family with sequence similarity 113, member B
chr16_-_30301634 1.890 NM_052838
SEPT1
septin 1
chr16_-_49272617 1.886 SNX20
sorting nexin 20
chr22_+_37747063 1.861 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr5_-_100266769 1.852 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr15_+_72620570 1.848 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr15_+_72861767 1.844 CSK
c-src tyrosine kinase
chr18_-_51219880 1.838 TCF4
transcription factor 4
chr2_-_197883569 1.835 ANKRD44
ankyrin repeat domain 44
chr22_+_29333069 1.822 NM_000355
NM_001184726
TCN2

transcobalamin II

chr8_-_6407882 1.817 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr9_+_115382990 1.816 RGS3
regulator of G-protein signaling 3
chr12_+_45896318 1.815 NM_138371
FAM113B
family with sequence similarity 113, member B
chr1_+_204797516 1.805 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr5_-_156468614 1.805 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chrX_-_44945025 1.801 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr19_-_59383944 1.780 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr7_-_23476497 1.774 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr14_+_74964261 1.769 NM_001135047
JDP2
Jun dimerization protein 2
chr17_+_69974361 1.763 CD300A
CD300a molecule
chr17_-_38087366 1.757 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr11_-_71458739 1.755 NUMA1
nuclear mitotic apparatus protein 1
chr12_-_46786107 1.732 SENP1
SUMO1/sentrin specific peptidase 1
chr13_+_107720475 1.728 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr6_+_336738 1.725 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chrX_-_74292800 1.720 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr7_+_149895390 1.711 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr11_-_58736897 1.706 NM_001039396
MPEG1
macrophage expressed 1
chr15_+_72861470 1.704 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr17_+_7402788 1.703 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr22_+_25398690 1.701 LOC388889
hypothetical LOC388889

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.50 1.03e-15 GO:0002376 immune system process
1.17 4.35e-08 GO:0044260 cellular macromolecule metabolic process
1.96 2.76e-07 GO:0050867 positive regulation of cell activation
2.01 2.85e-07 GO:0051251 positive regulation of lymphocyte activation
1.28 3.90e-07 GO:0010467 gene expression
1.25 4.27e-07 GO:0090304 nucleic acid metabolic process
1.46 4.65e-07 GO:0006955 immune response
1.94 7.81e-07 GO:0002696 positive regulation of leukocyte activation
1.29 9.74e-07 GO:0016070 RNA metabolic process
1.22 1.58e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 4.78e-06 GO:0034645 cellular macromolecule biosynthetic process
1.37 8.16e-06 GO:0032774 RNA biosynthetic process
1.80 1.23e-05 GO:0051249 regulation of lymphocyte activation
1.27 1.25e-05 GO:0009059 macromolecule biosynthetic process
1.74 1.55e-05 GO:0050865 regulation of cell activation
1.43 1.71e-05 GO:0002682 regulation of immune system process
1.75 1.89e-05 GO:0002694 regulation of leukocyte activation
2.00 2.07e-05 GO:0050870 positive regulation of T cell activation
1.13 4.59e-05 GO:0043170 macromolecule metabolic process
1.06 6.31e-05 GO:0009987 cellular process
1.09 6.37e-05 GO:0065007 biological regulation
1.85 8.23e-05 GO:0050863 regulation of T cell activation
1.10 9.18e-05 GO:0050794 regulation of cellular process
1.52 1.31e-04 GO:0002684 positive regulation of immune system process
1.11 2.89e-04 GO:0044237 cellular metabolic process
1.47 3.05e-04 GO:0001775 cell activation
1.09 5.09e-04 GO:0050789 regulation of biological process
1.66 7.37e-04 GO:0045321 leukocyte activation
1.48 9.77e-04 GO:0050776 regulation of immune response
1.73 1.05e-03 GO:0046649 lymphocyte activation
1.13 2.19e-03 GO:0051716 cellular response to stimulus
1.73 2.29e-03 GO:0002764 immune response-regulating signaling pathway
2.26 2.95e-03 GO:0031294 lymphocyte costimulation
2.26 2.95e-03 GO:0031295 T cell costimulation
1.72 4.33e-03 GO:0002757 immune response-activating signal transduction
1.15 4.64e-03 GO:0007165 signal transduction
1.89 5.37e-03 GO:0042110 T cell activation
1.98 6.34e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.48 7.98e-03 GO:0016568 chromatin modification
1.31 9.52e-03 GO:0006351 transcription, DNA-dependent
1.36 1.11e-02 GO:0051276 chromosome organization
1.42 1.12e-02 GO:0006325 chromatin organization
1.17 1.27e-02 GO:0006950 response to stress
2.01 1.31e-02 GO:0019080 viral genome expression
2.01 1.31e-02 GO:0019083 viral transcription
1.13 1.32e-02 GO:0023052 signaling
1.91 1.69e-02 GO:0006414 translational elongation
1.17 2.17e-02 GO:0048522 positive regulation of cellular process
1.17 2.24e-02 GO:0044249 cellular biosynthetic process
1.51 2.68e-02 GO:0002520 immune system development
1.15 2.95e-02 GO:0048518 positive regulation of biological process
1.13 3.08e-02 GO:0031323 regulation of cellular metabolic process
1.09 3.21e-02 GO:0044238 primary metabolic process
1.63 3.43e-02 GO:0022411 cellular component disassembly
1.63 3.43e-02 GO:0071845 cellular component disassembly at cellular level
1.84 4.05e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 4.18e-07 GO:0005634 nucleus
1.06 1.28e-06 GO:0044424 intracellular part
1.06 1.29e-06 GO:0005622 intracellular
1.28 1.69e-05 GO:0005654 nucleoplasm
1.24 1.70e-05 GO:0031981 nuclear lumen
1.22 1.80e-05 GO:0044428 nuclear part
1.07 3.57e-05 GO:0043226 organelle
1.11 3.77e-05 GO:0044446 intracellular organelle part
1.07 3.86e-05 GO:0043229 intracellular organelle
1.11 4.30e-05 GO:0044422 organelle part
1.08 4.32e-05 GO:0043227 membrane-bounded organelle
1.08 5.21e-05 GO:0043231 intracellular membrane-bounded organelle
1.20 2.34e-04 GO:0005829 cytosol
1.18 3.93e-04 GO:0031974 membrane-enclosed lumen
1.18 5.73e-04 GO:0043233 organelle lumen
1.18 8.98e-04 GO:0070013 intracellular organelle lumen
1.40 1.30e-03 GO:0030529 ribonucleoprotein complex
1.13 2.52e-03 GO:0032991 macromolecular complex
1.56 8.08e-03 GO:0016604 nuclear body
2.92 1.42e-02 GO:0070603 SWI/SNF-type complex
1.85 2.00e-02 GO:0016585 chromatin remodeling complex
1.02 4.06e-02 GO:0005623 cell
1.02 4.83e-02 GO:0044464 cell part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 7.14e-12 GO:0005515 protein binding
1.20 8.58e-08 GO:0003676 nucleic acid binding
1.19 1.41e-04 GO:0003677 DNA binding
1.05 2.02e-04 GO:0005488 binding
1.34 2.11e-04 GO:0003723 RNA binding
1.39 9.14e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.43 1.25e-02 GO:0003712 transcription cofactor activity
1.42 1.44e-02 GO:0000988 protein binding transcription factor activity
1.42 1.44e-02 GO:0000989 transcription factor binding transcription factor activity
1.25 1.74e-02 GO:0001071 nucleic acid binding transcription factor activity
1.25 1.74e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 2.12e-02 GO:0030695 GTPase regulator activity