Motif ID: SPZ1.p2

Z-value: 1.007


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79651545-0.165.5e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_26935883 1.129 NM_004949
NM_024422
 DSC2

desmocollin 2

chr12_-_52980914 1.038 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr17_+_42641712 0.910 NM_002476
 MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr2_-_220144254 0.868 OBSL1
obscurin-like 1
chr8_-_144887876 0.800 NM_198488
 FAM83H
family with sequence similarity 83, member H
chr19_+_40431678 0.750 LSR
lipolysis stimulated lipoprotein receptor
chr20_-_42457717 0.697


chr7_-_103417198 0.693 NM_005045
NM_173054
 RELN

reelin

chr6_-_116488458 0.684 NM_002031
 FRK
fyn-related kinase
chr9_+_70509925 0.683 NM_003558
 PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_+_32992131 0.677


chr1_-_11909042 0.674 NM_138346
 KIAA2013
KIAA2013
chr16_+_65701284 0.670 NM_025187
 C16orf70
chromosome 16 open reading frame 70
chr3_-_24511456 0.668 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr12_-_52980984 0.655 NM_001136023
 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chrX_+_105856531 0.638 NM_194463
 RNF128
ring finger protein 128
chr16_-_66535457 0.635 NM_000229
 LCAT
lecithin-cholesterol acyltransferase
chr16_+_65701428 0.629


chr3_-_24511180 0.614 NM_001128176
NM_000461
NM_001128177
 THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr2_+_119905812 0.607 NM_183240
 TMEM37
transmembrane protein 37

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
1.43 1.90e-03 GO:0051253 negative regulation of RNA metabolic process
1.43 2.21e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.39 8.41e-03 GO:0048666 neuron development
1.38 1.28e-03 GO:0030182 neuron differentiation
1.38 6.30e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.38 6.48e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.37 1.07e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.29e-04 GO:0022008 neurogenesis
1.36 1.83e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.35 1.52e-04 GO:0048468 cell development
1.35 6.56e-04 GO:0048699 generation of neurons
1.35 1.26e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.38e-02 GO:0010628 positive regulation of gene expression
1.35 4.42e-02 GO:0010629 negative regulation of gene expression
1.34 5.01e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 2.30e-02 GO:0009890 negative regulation of biosynthetic process
1.34 3.62e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.33 6.18e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.33 3.91e-02 GO:0051254 positive regulation of RNA metabolic process
1.32 3.82e-07 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.13 2.12e-02 GO:0034708 methyltransferase complex
2.13 2.12e-02 GO:0035097 histone methyltransferase complex
1.50 3.30e-02 GO:0000785 chromatin
1.38 5.49e-04 GO:0030054 cell junction
1.38 3.39e-02 GO:0043005 neuron projection
1.26 3.96e-04 GO:0005654 nucleoplasm
1.20 1.95e-04 GO:0070013 intracellular organelle lumen
1.20 2.84e-03 GO:0031981 nuclear lumen
1.19 2.43e-04 GO:0031974 membrane-enclosed lumen
1.19 2.76e-04 GO:0043233 organelle lumen
1.18 3.18e-03 GO:0044428 nuclear part
1.15 2.36e-04 GO:0032991 macromolecular complex
1.15 1.15e-03 GO:0043234 protein complex
1.12 4.72e-06 GO:0044422 organelle part
1.12 1.62e-05 GO:0044446 intracellular organelle part
1.10 8.78e-04 GO:0005634 nucleus
1.09 8.19e-09 GO:0043226 organelle
1.09 1.93e-08 GO:0043229 intracellular organelle
1.09 3.69e-07 GO:0043227 membrane-bounded organelle
1.09 4.60e-07 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.59 3.19e-02 GO:0003682 chromatin binding
1.32 3.45e-03 GO:0019899 enzyme binding
1.30 4.05e-02 GO:0043565 sequence-specific DNA binding
1.29 3.06e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.29 1.82e-02 GO:0016301 kinase activity
1.27 5.10e-03 GO:0001071 nucleic acid binding transcription factor activity
1.27 5.10e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.25 2.42e-02 GO:0030528 transcription regulator activity
1.14 1.77e-12 GO:0005515 protein binding
1.05 2.97e-04 GO:0005488 binding