Motif ID: SPZ1.p2

Z-value: 1.007


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79651545-0.165.5e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_26935883 1.129 NM_004949
NM_024422
DSC2

desmocollin 2

chr12_-_52980914 1.038 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr17_+_42641712 0.910 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr2_-_220144254 0.868 OBSL1
obscurin-like 1
chr8_-_144887876 0.800 NM_198488
FAM83H
family with sequence similarity 83, member H
chr19_+_40431678 0.750 LSR
lipolysis stimulated lipoprotein receptor
chr20_-_42457717 0.697


chr7_-_103417198 0.693 NM_005045
NM_173054
RELN

reelin

chr6_-_116488458 0.684 NM_002031
FRK
fyn-related kinase
chr9_+_70509925 0.683 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_+_32992131 0.677


chr1_-_11909042 0.674 NM_138346
KIAA2013
KIAA2013
chr16_+_65701284 0.670 NM_025187
C16orf70
chromosome 16 open reading frame 70
chr3_-_24511456 0.668 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr12_-_52980984 0.655 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chrX_+_105856531 0.638 NM_194463
RNF128
ring finger protein 128
chr16_-_66535457 0.635 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr16_+_65701428 0.629


chr3_-_24511180 0.614 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr2_+_119905812 0.607 NM_183240
TMEM37
transmembrane protein 37
chr20_-_30636535 0.600 LOC284804
hypothetical protein LOC284804
chr3_-_13436802 0.568 NM_024923
NUP210
nucleoporin 210kDa
chrX_-_128485121 0.568 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr6_-_138231006 0.544


chr1_-_21868380 0.535 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_-_54350457 0.524 NM_002152
HRC
histidine rich calcium binding protein
chr17_+_42641426 0.508 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr19_+_40223249 0.498 NM_002151
NM_182983
HPN

hepsin

chr6_-_13819463 0.485 RANBP9
RAN binding protein 9
chr19_+_45799060 0.477 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr1_-_20684858 0.473 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_7682355 0.460


chr1_-_9892852 0.459 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr17_+_33761234 0.444 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr7_+_94374862 0.442 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr1_+_159462456 0.437 NM_032174
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr1_+_199130571 0.433 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr20_-_22513050 0.426 NM_021784
FOXA2
forkhead box A2
chr17_+_72795567 0.422 NM_001113492
SEPT9
septin 9
chr16_+_84202515 0.422 NM_001134473
KIAA0182
KIAA0182
chr3_-_13436725 0.421 NUP210
nucleoporin 210kDa
chr14_-_20975241 0.409 NM_020920
CHD8
chromodomain helicase DNA binding protein 8
chr1_-_109627290 0.408 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chrX_-_132947290 0.406 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr4_-_187884721 0.405


chr19_+_40431618 0.403 LSR
lipolysis stimulated lipoprotein receptor
chrX_+_70232362 0.401 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr1_-_159459999 0.400 NM_001643
APOA2
apolipoprotein A-II
chr3_-_48445719 0.393 NM_002673
PLXNB1
plexin B1
chr3_-_187025438 0.392 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_-_31853027 0.390 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr14_-_22516271 0.387 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr7_+_77163665 0.385 NM_198467
RSBN1L
round spermatid basic protein 1-like
chr1_+_32979930 0.383 NM_020888
KIAA1522
KIAA1522
chr6_+_32090516 0.381 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr6_+_37245860 0.379 NM_002648
PIM1
pim-1 oncogene
chrX_-_132947141 0.378 GPC3
glypican 3
chr20_-_32877029 0.375 NM_014071
NCOA6
nuclear receptor coactivator 6
chr19_+_40431359 0.371 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr14_-_60260780 0.369 SIX4
SIX homeobox 4
chr1_+_27541086 0.369 SYTL1
synaptotagmin-like 1
chr9_-_106730157 0.361 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_-_109627266 0.355 PSRC1
proline/serine-rich coiled-coil 1
chr1_-_109627206 0.353 PSRC1
proline/serine-rich coiled-coil 1
chr19_-_17217022 0.353 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr17_-_1499849 0.351 NM_031430
RILP
Rab interacting lysosomal protein
chr7_+_101247601 0.345 NM_181552
CUX1
cut-like homeobox 1
chrX_-_128485062 0.340 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr17_+_31975611 0.339 GGNBP2
gametogenetin binding protein 2
chr16_-_66535923 0.339 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr13_-_33148899 0.338 STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_48017223 0.338 NM_001008223
C1QL4
complement component 1, q subcomponent-like 4
chr12_+_7174230 0.337 NM_014718
CLSTN3
calsyntenin 3
chr17_-_38081967 0.335 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr16_+_28741861 0.332 ATXN2L
ataxin 2-like
chr17_+_69939806 0.331 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_+_171280944 0.331 SP5
Sp5 transcription factor
chr11_+_12987455 0.330 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr11_-_116168316 0.327 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr6_+_43151922 0.326 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr17_+_44325127 0.325 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr3_-_187025501 0.324 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr7_-_100077072 0.322 NM_003227
TFR2
transferrin receptor 2
chr6_-_119712596 0.318 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr14_-_64416307 0.317 SPTB
spectrin, beta, erythrocytic
chr2_-_42873179 0.317 NM_012205
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr9_-_126573349 0.317 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr11_-_47164514 0.316 NM_001184974
NM_016223
PACSIN3

protein kinase C and casein kinase substrate in neurons 3

chr20_-_50241581 0.315 ZFP64
zinc finger protein 64 homolog (mouse)
chr16_+_49139694 0.311 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr17_-_46298671 0.307 TOB1
transducer of ERBB2, 1
chr11_-_57039721 0.306 NM_003627
SLC43A1
solute carrier family 43, member 1
chrX_-_106033202 0.305 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr16_-_15644465 0.303 NM_001184998
NM_001184999
NM_014647
KIAA0430


KIAA0430


chr22_-_17546234 0.302 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr9_+_115957537 0.301 COL27A1
collagen, type XXVII, alpha 1
chr2_+_219780192 0.299 ZFAND2B
zinc finger, AN1-type domain 2B
chr12_+_56621581 0.299 XRCC6BP1
XRCC6 binding protein 1
chr16_-_4262696 0.296 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr17_-_36469869 0.296 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr17_-_40858775 0.295 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr1_+_166172679 0.295 DCAF6
DDB1 and CUL4 associated factor 6
chr8_+_76482661 0.294 HNF4G
hepatocyte nuclear factor 4, gamma
chr6_+_30959839 0.294 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_24302597 0.290 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr19_-_6671585 0.286 NM_000064
C3
complement component 3
chr14_+_34521854 0.286 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr2_+_219779737 0.286 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr22_+_38720881 0.281 NM_138435
FAM83F
family with sequence similarity 83, member F
chr17_+_35147697 0.281 NM_005310
GRB7
growth factor receptor-bound protein 7
chr6_+_150112537 0.280 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_-_77163475 0.280


chr14_+_34521945 0.276 SRP54
signal recognition particle 54kDa
chr12_+_52665196 0.274 NM_017409
HOXC10
homeobox C10
chr11_+_117812282 0.274 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr1_-_42573210 0.270 NM_001198851
FOXJ3
forkhead box J3
chr6_+_150112511 0.268 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_-_24302450 0.267 PHF12
PHD finger protein 12
chr4_-_22126437 0.265 NM_145290
GPR125
G protein-coupled receptor 125
chr2_-_220144427 0.264 OBSL1
obscurin-like 1
chr1_+_227473458 0.263 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr14_-_22974707 0.263 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr16_+_2954217 0.262 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr3_-_95175282 0.262 PROS1
protein S (alpha)
chr16_+_29819647 0.262 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr3_-_159306214 0.262


chr19_-_56585603 0.262 NM_001193623
LOC147646
hypothetical protein LOC147646
chr16_+_29597965 0.261 QPRT
quinolinate phosphoribosyltransferase
chr3_+_9933763 0.261 NM_032732
NM_153460
NM_153461
IL17RC


interleukin 17 receptor C


chr5_+_75734759 0.260 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_55808696 0.259 LRP1
low density lipoprotein receptor-related protein 1
chr10_+_88506320 0.259 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr22_+_38903825 0.259 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_-_91394881 0.259 PANK1
pantothenate kinase 1
chr6_-_159340737 0.258 RSPH3
radial spoke 3 homolog (Chlamydomonas)
chrX_+_48529905 0.258 NM_002049
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr2_-_220144511 0.258 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr11_-_70641267 0.258 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr7_+_128219307 0.257 NM_022742
CCDC136
coiled-coil domain containing 136
chr19_+_50100843 0.257 NM_000041
APOE
apolipoprotein E
chr12_+_106236281 0.256 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr9_-_79835970 0.256 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr4_+_144477432 0.255 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr5_+_137829077 0.255 NM_001964
EGR1
early growth response 1
chr1_+_90060131 0.255 LRRC8D
leucine rich repeat containing 8 family, member D
chr2_-_36384 0.254 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr16_-_49742008 0.254 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr14_-_37133927 0.254 FOXA1
forkhead box A1
chr11_+_123600553 0.253 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr2_-_38683119 0.252 HNRPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_-_151855413 0.251 NM_020672
S100A14
S100 calcium binding protein A14
chr10_+_17726129 0.250 NM_003473
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr17_-_35017691 0.250 NM_006160
NEUROD2
neurogenic differentiation 2
chr6_-_159340784 0.249 RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr1_-_150070849 0.248 NM_005060
RORC
RAR-related orphan receptor C
chr3_+_125786195 0.247 NM_007064
KALRN
kalirin, RhoGEF kinase
chr11_-_32413486 0.247 WT1
Wilms tumor 1
chr14_-_23686269 0.246 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_+_28785087 0.246 SH2B1
SH2B adaptor protein 1
chr10_-_21854616 0.245 NM_207371
C10orf140
chromosome 10 open reading frame 140
chr17_-_39556483 0.245 HDAC5
histone deacetylase 5
chr1_+_3679168 0.245 NM_001163724
LOC388588
hypothetical protein LOC388588
chr17_+_44429748 0.244 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr13_+_92677012 0.244 NM_005708
GPC6
glypican 6
chr1_+_57093030 0.243 NM_000562
C8A
complement component 8, alpha polypeptide
chr12_+_55808514 0.243 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr16_+_29597829 0.240 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr17_-_35017650 0.238 NEUROD2
neurogenic differentiation 2
chr3_-_159306532 0.237 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr12_+_54700955 0.237 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr12_+_120726317 0.237 SETD1B
SET domain containing 1B
chr11_+_45900731 0.236 GYLTL1B
glycosyltransferase-like 1B
chr7_+_137795719 0.235 TRIM24
tripartite motif containing 24
chr20_-_22512893 0.234 FOXA2
forkhead box A2
chr6_+_150112549 0.231 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr5_-_134397470 0.231 PITX1
paired-like homeodomain 1
chr17_-_75385371 0.231 NM_020649
CBX8
chromobox homolog 8
chr17_-_62671738 0.231 HELZ
helicase with zinc finger
chr16_+_15644624 0.230 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr7_-_100647585 0.230 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_-_166172901 0.229 NM_001143674
BRP44
brain protein 44
chr1_-_143706300 0.229 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr13_-_49597776 0.229 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr18_+_3439972 0.228 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr1_-_227544836 0.227 C1orf96
chromosome 1 open reading frame 96
chr16_+_28741908 0.226 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr14_-_60260211 0.225 NM_017420
SIX4
SIX homeobox 4
chr20_-_33335919 0.225 NM_181468
EIF6
eukaryotic translation initiation factor 6
chr1_-_227545310 0.223 NM_145257
C1orf96
chromosome 1 open reading frame 96
chr16_+_29582069 0.223 NM_003123
SPN
sialophorin
chr12_+_48303607 0.221 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_10540328 0.221 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr14_-_20636337 0.220 ZNF219
zinc finger protein 219
chr11_+_46679140 0.219 NM_001184751
ZNF408
zinc finger protein 408
chr1_+_201862548 0.218 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr11_-_27450808 0.218 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr6_+_41863386 0.218 TOMM6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr18_+_30812205 0.217 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_-_70563489 0.217 LMBRD1
LMBR1 domain containing 1
chr16_+_30667120 0.217 NM_000294
NM_001172432
PHKG2

phosphorylase kinase, gamma 2 (testis)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 3.82e-07 GO:0007399 nervous system development
1.07 2.71e-06 GO:0009987 cellular process
1.36 1.29e-04 GO:0022008 neurogenesis
1.35 1.52e-04 GO:0048468 cell development
1.35 6.56e-04 GO:0048699 generation of neurons
1.10 7.88e-04 GO:0050794 regulation of cellular process
1.13 1.00e-03 GO:0044260 cellular macromolecule metabolic process
1.38 1.28e-03 GO:0030182 neuron differentiation
1.09 1.33e-03 GO:0065007 biological regulation
1.43 1.90e-03 GO:0051253 negative regulation of RNA metabolic process
1.43 2.21e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.09 2.34e-03 GO:0050789 regulation of biological process
1.10 3.59e-03 GO:0044237 cellular metabolic process
1.30 4.67e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.34 5.01e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 6.18e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.11 6.19e-03 GO:0043170 macromolecule metabolic process
1.14 6.20e-03 GO:0023052 signaling
1.38 6.30e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.38 6.48e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.39 8.41e-03 GO:0048666 neuron development
1.27 9.13e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.37 1.07e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 1.07e-02 GO:0048731 system development
1.15 1.09e-02 GO:0048856 anatomical structure development
1.25 1.17e-02 GO:0009893 positive regulation of metabolic process
1.35 1.26e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.38e-02 GO:0010628 positive regulation of gene expression
1.36 1.83e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 1.90e-02 GO:0009653 anatomical structure morphogenesis
1.18 1.95e-02 GO:0048523 negative regulation of cellular process
1.34 2.30e-02 GO:0009890 negative regulation of biosynthetic process
1.25 2.39e-02 GO:0031325 positive regulation of cellular metabolic process
1.13 2.45e-02 GO:0032502 developmental process
1.09 2.46e-02 GO:0044238 primary metabolic process
1.14 2.52e-02 GO:0007275 multicellular organismal development
1.29 2.74e-02 GO:0006351 transcription, DNA-dependent
1.13 2.92e-02 GO:0031323 regulation of cellular metabolic process
1.08 3.55e-02 GO:0008152 metabolic process
1.34 3.62e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.33 3.91e-02 GO:0051254 positive regulation of RNA metabolic process
1.18 4.37e-02 GO:0030154 cell differentiation
1.35 4.42e-02 GO:0010629 negative regulation of gene expression
1.14 4.98e-02 GO:0034641 cellular nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 3.68e-10 GO:0044424 intracellular part
1.07 2.10e-09 GO:0005622 intracellular
1.09 8.19e-09 GO:0043226 organelle
1.09 1.93e-08 GO:0043229 intracellular organelle
1.09 3.69e-07 GO:0043227 membrane-bounded organelle
1.09 4.60e-07 GO:0043231 intracellular membrane-bounded organelle
1.12 4.72e-06 GO:0044422 organelle part
1.09 8.01e-06 GO:0005737 cytoplasm
1.12 1.62e-05 GO:0044446 intracellular organelle part
1.20 1.95e-04 GO:0070013 intracellular organelle lumen
1.15 2.36e-04 GO:0032991 macromolecular complex
1.19 2.43e-04 GO:0031974 membrane-enclosed lumen
1.19 2.76e-04 GO:0043233 organelle lumen
1.26 3.96e-04 GO:0005654 nucleoplasm
1.38 5.49e-04 GO:0030054 cell junction
1.10 8.78e-04 GO:0005634 nucleus
1.15 1.15e-03 GO:0043234 protein complex
1.09 1.88e-03 GO:0044444 cytoplasmic part
1.20 2.84e-03 GO:0031981 nuclear lumen
1.18 3.18e-03 GO:0044428 nuclear part
1.03 1.12e-02 GO:0044464 cell part
1.03 1.18e-02 GO:0005623 cell
2.13 2.12e-02 GO:0034708 methyltransferase complex
2.13 2.12e-02 GO:0035097 histone methyltransferase complex
1.50 3.30e-02 GO:0000785 chromatin
1.38 3.39e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.77e-12 GO:0005515 protein binding
1.05 2.97e-04 GO:0005488 binding
1.29 3.06e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.32 3.45e-03 GO:0019899 enzyme binding
1.27 5.10e-03 GO:0001071 nucleic acid binding transcription factor activity
1.27 5.10e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 1.82e-02 GO:0016301 kinase activity
1.25 2.42e-02 GO:0030528 transcription regulator activity
1.59 3.19e-02 GO:0003682 chromatin binding
1.30 4.05e-02 GO:0043565 sequence-specific DNA binding