Motif ID: STAT2,4,6.p2

Z-value: 1.905


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT2chr12_-_550401830.448.7e-02Click!
STAT4chr2_-_191724169-0.322.2e-01Click!
STAT6chr12_-_557913880.273.1e-01Click!


Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_188945921 4.300 BCL6
B-cell CLL/lymphoma 6
chr3_-_188946168 2.980 NM_001706
 BCL6
B-cell CLL/lymphoma 6
chr17_-_73867748 2.086 NM_003955
 SOCS3
suppressor of cytokine signaling 3
chr9_-_116920232 1.958 NM_002160
 TNC
tenascin C
chr12_-_92488767 1.935


chr12_+_92488932 1.802 SOCS2
suppressor of cytokine signaling 2
chr19_-_49552638 1.722 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr8_+_103889733 1.639 FLJ45248
FLJ45248 protein
chr12_+_51730101 1.543 NM_170754
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr20_+_2743613 1.519 NM_080739
 C20orf141
chromosome 20 open reading frame 141
chrX_+_105932536 1.504 NM_017752
NM_198881
 TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr7_-_5429702 1.468 NM_001080495
 TNRC18
trinucleotide repeat containing 18
chr12_-_51200347 1.462 NM_000424
 KRT5
keratin 5
chr3_+_189353502 1.441 LPP
LIM domain containing preferred translocation partner in lipoma
chr5_+_38882017 1.414 OSMR
oncostatin M receptor
chr6_-_35572694 1.410 NM_003214
 TEAD3
TEA domain family member 3
chr18_+_59295123 1.309 NM_002639
 SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_+_72827227 1.260 SEPT9
septin 9
chr19_+_49248003 1.208 NM_013361
 ZNF223
zinc finger protein 223
chr17_+_72827185 1.175 NM_006640
 SEPT9
septin 9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.38 1.19e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
2.10 2.57e-02 GO:0034329 cell junction assembly
2.05 2.10e-02 GO:0034330 cell junction organization
1.22 1.64e-02 GO:0071842 cellular component organization at cellular level
1.20 4.63e-02 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.17 1.45e-02 GO:0005925 focal adhesion
2.06 3.22e-02 GO:0030055 cell-substrate junction
2.06 3.92e-02 GO:0005924 cell-substrate adherens junction
2.04 2.12e-03 GO:0005912 adherens junction
1.88 1.31e-02 GO:0070161 anchoring junction
1.12 9.71e-03 GO:0005634 nucleus
1.11 3.17e-05 GO:0005737 cytoplasm
1.10 9.04e-05 GO:0043231 intracellular membrane-bounded organelle
1.10 9.51e-05 GO:0043227 membrane-bounded organelle
1.09 1.44e-04 GO:0043229 intracellular organelle
1.09 1.49e-04 GO:0043226 organelle
1.08 5.94e-07 GO:0044424 intracellular part
1.08 3.64e-06 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.12 2.10e-04 GO:0005515 protein binding