Motif ID: TBX4,5.p2

Z-value: 1.516


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBX4chr17_+_56884560-0.361.7e-01Click!
TBX5chr12_-_113330574-0.322.2e-01Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_4621924 2.123 NM_003963
 TM4SF5
transmembrane 4 L six family member 5
chr1_-_205161821 2.112 NM_001193338
NM_001142473
NM_005449
 FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_6958282 1.734 NM_080914
 ASGR2
asialoglycoprotein receptor 2
chr19_-_43800374 1.651 NM_001042600
NM_007181
 MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr17_+_53769562 1.552 LOC100506779
hypothetical LOC100506779
chr19_-_10074332 1.420 NM_031917
 ANGPTL6
angiopoietin-like 6
chr17_+_22823151 1.413 NM_014238
 KSR1
kinase suppressor of ras 1
chr10_+_114125003 1.361 NM_203380
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_+_31731647 1.337 NM_019101
 APOM
apolipoprotein M
chr6_+_31651319 1.284 NM_000594
 TNF
tumor necrosis factor
chr4_-_105631915 1.274 NM_025212
 CXXC4
CXXC finger protein 4
chr3_-_49701085 1.261 NM_020998
 MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_+_18312365 1.255 NM_017712
 FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr14_+_94148466 1.218 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chrX_+_46825179 1.177 RGN
regucalcin (senescence marker protein-30)
chr6_-_25044156 1.170 FAM65B
family with sequence similarity 65, member B
chr22_-_28992787 1.164 NM_020530
 OSM
oncostatin M
chr3_+_187813553 1.155 AHSG
alpha-2-HS-glycoprotein
chr2_+_171280046 1.116 NM_001003845
 SP5
Sp5 transcription factor
chr11_-_118405288 1.112 NM_001164280
 SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.81 2.20e-03 GO:0006695 cholesterol biosynthetic process
3.62 1.12e-03 GO:0016126 sterol biosynthetic process
1.59 2.65e-02 GO:0006066 alcohol metabolic process
1.45 3.09e-02 GO:0006955 immune response
1.12 1.27e-03 GO:0065007 biological regulation
1.12 8.50e-03 GO:0050789 regulation of biological process
1.11 4.30e-02 GO:0050794 regulation of cellular process
1.08 2.74e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.53 3.26e-04 GO:0005789 endoplasmic reticulum membrane
1.52 3.95e-04 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.50 2.33e-04 GO:0044432 endoplasmic reticulum part
1.40 5.11e-04 GO:0005783 endoplasmic reticulum
1.29 5.84e-03 GO:0012505 endomembrane system
1.23 1.17e-02 GO:0031090 organelle membrane
1.12 1.16e-05 GO:0005737 cytoplasm
1.12 8.82e-03 GO:0044444 cytoplasmic part
1.12 1.62e-02 GO:0044446 intracellular organelle part
1.12 1.93e-02 GO:0044422 organelle part
1.07 4.54e-02 GO:0043226 organelle
1.06 5.38e-03 GO:0005622 intracellular
1.06 1.68e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.41 3.07e-02 GO:0019899 enzyme binding
1.14 2.42e-06 GO:0005515 protein binding