Motif ID: TCF4_dimer.p2

Z-value: 3.927


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_514063590.601.4e-02Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_49996353 11.938 NM_003068
 SNAI2
snail homolog 2 (Drosophila)
chr17_+_36493927 9.042 NM_033061
 KRTAP4-7
keratin associated protein 4-7
chr16_-_30983909 7.996 NM_001172669
NM_001172670
 ZNF668

zinc finger protein 668

chr15_+_72006015 7.094 LOXL1
lysyl oxidase-like 1
chr3_-_87122936 6.972 NM_016206
 VGLL3
vestigial like 3 (Drosophila)
chr1_+_46151845 6.966 MAST2
microtubule associated serine/threonine kinase 2
chr9_-_35679799 6.478 TPM2
tropomyosin 2 (beta)
chr9_-_35679902 6.084 NM_003289
NM_213674
 TPM2

tropomyosin 2 (beta)

chr11_-_6298284 6.003 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr1_+_181259317 6.001


chr15_-_46725087 5.980 NM_000138
 FBN1
fibrillin 1
chr8_-_41641881 5.978 NM_001142445
NM_020478
NM_020480
 ANK1


ankyrin 1, erythrocytic


chr2_-_175337386 5.927 NM_000079
NM_001039523
 CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr2_+_33213111 5.884 NM_000627
NM_001166264
NM_001166265
NM_001166266
 LTBP1



latent transforming growth factor beta binding protein 1



chr1_-_143643064 5.848 PDE4DIP
phosphodiesterase 4D interacting protein
chr22_-_20235372 5.455 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr1_+_221955876 5.387 NM_001146068
 CAPN2
calpain 2, (m/II) large subunit
chr2_+_219991342 5.375 NM_001927
 DES
desmin
chr2_+_85834111 5.311 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr11_-_47427263 5.099 NM_005055
NM_032645
 RAPSN

receptor-associated protein of the synapse


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
1.90 3.99e-02 GO:0050770 regulation of axonogenesis
1.65 3.56e-04 GO:0007517 muscle organ development
1.56 2.80e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.54 3.98e-04 GO:0061061 muscle structure development
1.51 1.93e-04 GO:0007411 axon guidance
1.45 1.97e-04 GO:0007409 axonogenesis
1.44 3.12e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.44 1.11e-02 GO:0060284 regulation of cell development
1.42 6.81e-04 GO:0048812 neuron projection morphogenesis
1.41 2.73e-05 GO:0048666 neuron development
1.40 6.25e-04 GO:0000904 cell morphogenesis involved in differentiation
1.39 1.26e-03 GO:0031175 neuron projection development
1.37 7.78e-08 GO:0022008 neurogenesis
1.37 2.05e-05 GO:0030182 neuron differentiation
1.36 2.10e-07 GO:0048468 cell development
1.36 1.20e-06 GO:0048699 generation of neurons
1.30 1.73e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 2.14e-02 GO:0032989 cellular component morphogenesis
1.29 5.70e-03 GO:2000026 regulation of multicellular organismal development
1.29 4.10e-02 GO:0030030 cell projection organization

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.99 3.13e-02 GO:0031674 I band
1.92 2.37e-06 GO:0030016 myofibril
1.91 5.69e-06 GO:0044449 contractile fiber part
1.91 4.91e-05 GO:0030017 sarcomere
1.90 1.96e-06 GO:0043292 contractile fiber
1.36 1.08e-02 GO:0031012 extracellular matrix
1.26 4.37e-02 GO:0030054 cell junction
1.16 1.89e-03 GO:0044459 plasma membrane part
1.10 3.37e-03 GO:0071944 cell periphery
1.10 4.53e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.07 4.42e-03 GO:0005515 protein binding