Motif ID: TEAD1.p2

Z-value: 5.678


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_126524270.802.0e-04Click!
TEAD4chr12_+_29387030.629.7e-03Click!
TEAD2chr19_-_545574500.391.4e-01Click!
TEAD3chr6_-_355726940.371.6e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_212791597 30.637 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_212791467 29.769 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr6_-_132314004 22.506 NM_001901
CTGF
connective tissue growth factor
chr3_-_135575925 21.352 NM_016201
AMOTL2
angiomotin like 2
chr4_+_184257337 21.031 NM_024949
WWC2
WW and C2 domain containing 2
chr15_+_37660568 18.769 NM_003246
THBS1
thrombospondin 1
chr19_+_39664706 17.689 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr6_-_128883125 16.104 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr10_+_123862430 15.160 TACC2
transforming, acidic coiled-coil containing protein 2
chr11_-_6298284 14.986 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr2_-_160972606 14.324 RBMS1
RNA binding motif, single stranded interacting protein 1
chr5_-_39460687 14.097 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_38505331 13.774 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr11_-_8788765 12.626 NM_213618
ST5
suppression of tumorigenicity 5
chr6_-_75972286 12.277 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr1_+_85819004 11.713 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_148422799 11.475 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr16_-_30983909 11.088 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr11_-_8789457 11.041 NM_139157
ST5
suppression of tumorigenicity 5
chr15_+_73728402 10.647 NM_153271
SNX33
sorting nexin 33

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.71 2.06e-02 GO:0007517 muscle organ development
2.40 7.01e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.40 1.93e-02 GO:0061061 muscle structure development
2.32 3.76e-02 GO:0001944 vasculature development
1.94 7.44e-04 GO:0007155 cell adhesion
1.94 7.44e-04 GO:0022610 biological adhesion
1.70 3.16e-02 GO:0048468 cell development
1.60 5.82e-03 GO:0009966 regulation of signal transduction
1.55 1.86e-02 GO:0009653 anatomical structure morphogenesis
1.49 2.14e-02 GO:0007166 cell surface receptor linked signaling pathway
1.46 4.13e-02 GO:0048513 organ development
1.41 2.95e-03 GO:0048731 system development
1.41 3.32e-02 GO:0042221 response to chemical stimulus
1.35 1.68e-02 GO:0048856 anatomical structure development
1.30 3.85e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
13.83 2.38e-02 GO:0001527 microfibril
5.04 8.43e-06 GO:0005604 basement membrane
4.22 1.25e-06 GO:0044420 extracellular matrix part
2.52 8.42e-05 GO:0005578 proteinaceous extracellular matrix
2.47 1.55e-05 GO:0031012 extracellular matrix
1.93 3.42e-07 GO:0044421 extracellular region part
1.76 2.67e-03 GO:0005615 extracellular space
1.57 6.43e-06 GO:0005576 extracellular region
1.29 1.51e-03 GO:0071944 cell periphery
1.28 4.60e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.49 1.65e-03 GO:0019838 growth factor binding
2.96 4.46e-02 GO:0008201 heparin binding
2.66 4.55e-02 GO:0005539 glycosaminoglycan binding
2.36 8.02e-04 GO:0003779 actin binding
1.75 2.69e-02 GO:0005509 calcium ion binding
1.18 1.07e-02 GO:0005515 protein binding