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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2B.p2

Z-value: 4.823

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_39664706	8.060	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr9_+_127549437	7.181	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr2_-_160972606	6.312		RBMS1	RNA binding motif, single stranded interacting protein 1
chr21_-_43671355	5.966	NM_173354	SIK1	salt-inducible kinase 1
chr4_+_89147821	5.545	NM_000297	PKD2	polycystic kidney disease 2 (autosomal dominant)
chr5_+_14196287	5.450	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr14_+_105012106	5.031	NM_001312	CRIP2	cysteine-rich protein 2
chr20_+_56701224	4.962	NM_024663	NPEPL1	aminopeptidase-like 1
chr10_+_11100111	4.805		CELF2	CUGBP, Elav-like family member 2
chr19_-_1518875	4.759	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr10_+_11100075	4.607		CELF2	CUGBP, Elav-like family member 2
chrX_+_9943793	4.605	NM_015691	WWC3	WWC family member 3
chr5_+_10617431	4.365	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr2_-_45090025	4.196	NM_016932	SIX2	SIX homeobox 2
chr2_-_127580975	4.018	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr1_-_95165089	3.968	NM_001839	CNN3	calponin 3, acidic
chr10_-_131652007	3.810	NM_001005463	EBF3	early B-cell factor 3
chr4_-_174327377	3.789
chr10_+_11099860	3.628	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr2_-_110769670	3.561	NM_001164463 NM_005054	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr6_-_165996031	3.542		LOC100132188	LP7097
chr3_-_38666122	3.505	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr2_+_241586927	3.491	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr14_-_29466562	3.490	NM_002742	PRKD1	protein kinase D1
chr4_+_14614462	3.437		CPEB2	cytoplasmic polyadenylation element binding protein 2
chr7_-_150576634	3.385		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr7_-_150576660	3.372	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_95165037	3.360		CNN3	calponin 3, acidic
chr2_-_239987629	3.352		HDAC4	histone deacetylase 4
chr3_+_23961739	3.279	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr22_+_36286350	3.246	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr3_-_130807865	3.239	NM_015103	PLXND1	plexin D1
chr19_+_16296632	3.164	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr18_-_24011349	3.147	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr13_-_109236897	3.119	NM_003749	IRS2	insulin receptor substrate 2
chr5_+_98132898	3.110	NM_001012761	RGMB	RGM domain family, member B
chr12_+_26003218	3.093	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr13_-_73606362	3.091		KLF12	Kruppel-like factor 12
chr7_+_55922623	3.079		ZNF713	zinc finger protein 713
chr4_+_3264509	3.052		RGS12	regulator of G-protein signaling 12
chr1_+_64012154	3.036	NM_001083592 NM_005012	ROR1	receptor tyrosine kinase-like orphan receptor 1
chr4_-_7991992	3.032	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr2_+_9264360	3.009		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr14_+_70178126	2.997	NM_015351	TTC9	tetratricopeptide repeat domain 9
chr2_+_5750229	2.939	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr22_-_48607449	2.918		BRD1	bromodomain containing 1
chr6_-_165995510	2.916	NM_001130690 NM_006661	PDE10A	phosphodiesterase 10A
chr15_+_29406335	2.876	NM_015995	KLF13	Kruppel-like factor 13
chr18_+_12648191	2.876
chr10_+_171410	2.868		ZMYND11	zinc finger, MYND-type containing 11
chr1_+_179148935	2.862	NM_020950	KIAA1614	KIAA1614
chr7_-_525336	2.843		PDGFA	platelet-derived growth factor alpha polypeptide
chr20_-_3944035	2.827	NM_007219 NM_001134337 NM_001134338	RNF24	ring finger protein 24
chr7_-_19123787	2.817	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr18_-_12647911	2.814	NM_001128626 NM_020148	SPIRE1	spire homolog 1 (Drosophila)
chr2_-_239987557	2.800	NM_006037	HDAC4	histone deacetylase 4
chr6_-_90119169	2.799		UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr22_-_20419975	2.792	NM_013313	YPEL1	yippee-like 1 (Drosophila)
chr8_-_80842452	2.763	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr19_+_16296734	2.739		KLF2	Kruppel-like factor 2 (lung)
chr7_-_525556	2.732		PDGFA	platelet-derived growth factor alpha polypeptide
chr14_+_58174489	2.714	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr4_-_140696740	2.689	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr7_+_151792052	2.675		LOC100128822	hypothetical LOC100128822
chr7_-_19123765	2.662		TWIST1	twist homolog 1 (Drosophila)
chr5_+_34692239	2.657		RAI14	retinoic acid induced 14
chr12_+_63958949	2.648	NM_001193461	MSRB3	methionine sulfoxide reductase B3
chr4_-_141896920	2.630	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr2_+_241023908	2.625		GPC1	glypican 1
chr18_-_5533967	2.596	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr10_+_128583984	2.581	NM_001380	DOCK1	dedicator of cytokinesis 1
chr13_-_40138607	2.580	NM_002015	FOXO1	forkhead box O1
chrX_+_154264931	2.575	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr16_+_87765661	2.557	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr6_-_3697244	2.528	NM_183373	C6orf145	chromosome 6 open reading frame 145
chr5_-_57791544	2.524	NM_006622	PLK2	polo-like kinase 2
chr18_-_12647736	2.521		SPIRE1	spire homolog 1 (Drosophila)
chr13_-_20533629	2.513		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr17_-_53387493	2.500		CUEDC1	CUE domain containing 1
chr6_+_72055229	2.490		OGFRL1	opioid growth factor receptor-like 1
chr1_+_148388870	2.489		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr6_-_90119158	2.485		UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr21_+_45318861	2.471	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr5_+_53849251	2.467	NM_001145427 NM_001102575 NM_052870	SNX18	sorting nexin 18
chr6_+_72055197	2.458	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr6_+_3696224	2.455
chr17_+_78630793	2.445	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr21_+_45649719	2.444
chr5_+_34692352	2.431	NM_001145520	RAI14	retinoic acid induced 14
chr4_-_186693574	2.415	NM_001114107 NM_014476	PDLIM3	PDZ and LIM domain 3
chr18_+_18969724	2.411	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr5_-_72779585	2.407		FOXD1	forkhead box D1
chr17_-_8006979	2.386	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_10193267	2.376	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr12_-_104153920	2.367	NM_018171	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr7_+_37926687	2.365	NM_017549	EPDR1	ependymin related protein 1 (zebrafish)
chr11_-_77806500	2.364	NM_080491	GAB2	GRB2-associated binding protein 2
chr1_+_181259317	2.361
chr20_-_60151835	2.353	NM_002792	PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr21_+_45649429	2.334	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr4_+_151218862	2.314	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr18_+_32131628	2.310	NM_025135	FHOD3	formin homology 2 domain containing 3
chr11_-_14337167	2.310	NM_012250	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr16_-_45735333	2.303		NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr9_-_38059082	2.302		SHB	Src homology 2 domain containing adaptor protein B
chr7_+_90731671	2.297	NM_003505	FZD1	frizzled homolog 1 (Drosophila)
chr4_-_1692776	2.297	NM_001127266 NM_138385	TMEM129	transmembrane protein 129
chr10_-_126097444	2.279		OAT	ornithine aminotransferase
chr7_-_150576957	2.276		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr7_+_1536847	2.272	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr3_+_160964574	2.271		SCHIP1	schwannomin interacting protein 1
chr11_+_86189138	2.262	NM_007173	PRSS23	protease, serine, 23
chr2_-_112907577	2.253	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr12_-_105165805	2.245	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr7_+_39629665	2.240	NM_005402	RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr6_-_90119008	2.236		UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr3_+_61522922	2.234		PTPRG	protein tyrosine phosphatase, receptor type, G
chr13_-_100125103	2.217	NM_001079669 NM_032813	TMTC4	transmembrane and tetratricopeptide repeat containing 4
chr19_+_1358664	2.201		DAZAP1	DAZ associated protein 1
chr11_+_12355600	2.198	NM_018222	PARVA	parvin, alpha
chr7_+_39629724	2.188		RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr16_-_45735403	2.186	NM_018092	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr7_+_39629782	2.177		RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr1_+_26671488	2.170	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr10_-_131652364	2.169		EBF3	early B-cell factor 3
chr16_-_79395379	2.168	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr1_+_181258952	2.166	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr2_+_242289983	2.164	NM_032329	ING5	inhibitor of growth family, member 5
chr16_-_21439195	2.155		SLC7A5P2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr17_+_1574782	2.132	NM_001163809	WDR81	WD repeat domain 81
chr4_-_1692574	2.131		TMEM129	transmembrane protein 129
chr13_+_75108450	2.125		LMO7	LIM domain 7
chr9_+_96807107	2.121		C9orf3	chromosome 9 open reading frame 3
chr16_-_70315151	2.120		PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
chr2_+_9264327	2.119	NM_001135191 NM_003887	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr20_-_60151802	2.117		PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr1_-_85703321	2.112	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr11_+_12652427	2.106	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr11_-_109672401	2.105	NM_002906	RDX	radixin
chr5_+_53849396	2.104		SNX18	sorting nexin 18
chr7_+_37926943	2.103		EPDR1	ependymin related protein 1 (zebrafish)
chr10_-_15250616	2.091	NM_004808	NMT2	N-myristoyltransferase 2
chr7_+_154720416	2.087	NM_005542 NM_198336 NM_198337	INSIG1	insulin induced gene 1
chr10_+_116571485	2.075	NM_001135051 NM_020940	FAM160B1	family with sequence similarity 160, member B1
chr17_-_19711580	2.070	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chr4_+_1842947	2.069		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr4_+_108965167	2.067	NM_001136258	SGMS2	sphingomyelin synthase 2
chr2_-_37752272	2.044		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr1_-_232811846	2.043	NM_001077397 NM_182972	IRF2BP2	interferon regulatory factor 2 binding protein 2
chr21_+_36993302	2.041
chr1_+_148388719	2.037	NM_016274	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr2_+_105727836	2.036	NM_001004722 NM_003581	NCK2	NCK adaptor protein 2
chr16_+_66153810	2.029	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr10_+_104394185	2.028	NM_030912	TRIM8	tripartite motif containing 8
chr10_+_69314347	2.023	NM_012238	SIRT1	sirtuin 1
chr16_+_85158357	2.021	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr5_-_179431491	2.014		RNF130	ring finger protein 130
chr15_-_53667800	2.011		PYGO1	pygopus homolog 1 (Drosophila)
chr12_+_63958689	2.010	NM_001031679 NM_001193460 NM_198080	MSRB3	methionine sulfoxide reductase B3
chr1_-_6243621	2.009	NM_207370	GPR153	G protein-coupled receptor 153
chr20_-_60151753	2.004		PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_96566190	1.996	NM_212481	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr2_+_65070030	1.993		SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_+_98084531	1.991	NM_002523	NPTX2	neuronal pentraxin II
chr7_+_882704	1.990	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr6_+_72055235	1.988		OGFRL1	opioid growth factor receptor-like 1
chr7_-_104816487	1.986
chr12_-_78608154	1.984		PAWR	PRKC, apoptosis, WT1, regulator
chr10_-_43464272	1.982	NM_006973	ZNF32	zinc finger protein 32
chr2_+_176702667	1.979	NM_019558	HOXD8	homeobox D8
chr12_-_41163680	1.974	NM_001144881	PRICKLE1	prickle homolog 1 (Drosophila)
chr1_-_5974997	1.973		NPHP4	nephronophthisis 4
chr12_+_50271283	1.972	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr16_+_415630	1.959	NM_014700	RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr8_+_32525269	1.952	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr10_+_23768203	1.950	NM_001145373	OTUD1	OTU domain containing 1
chr2_-_1727220	1.949		PXDN	peroxidasin homolog (Drosophila)
chr12_+_66328760	1.946	NM_003583 NM_006482	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr11_-_118739838	1.946		USP2	ubiquitin specific peptidase 2
chr1_-_200380321	1.944		ARL8A	ADP-ribosylation factor-like 8A
chr14_+_99329198	1.927	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr7_+_30140868	1.919	NM_152793	C7orf41	chromosome 7 open reading frame 41
chr19_-_2187648	1.918		PLEKHJ1	pleckstrin homology domain containing, family J member 1
chr4_-_177950658	1.900	NM_005429	VEGFC	vascular endothelial growth factor C
chr19_+_1358531	1.892	NM_018959 NM_170711	DAZAP1	DAZ associated protein 1
chr17_+_27838041	1.891	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr9_-_122516399	1.890	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr1_+_148389039	1.890		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr20_+_39199263	1.885		PLCG1	phospholipase C, gamma 1
chr10_+_44816278	1.885	NM_006963	ZNF22	zinc finger protein 22 (KOX 15)
chr11_+_72696963	1.880		ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr14_+_76297536	1.878
chr6_-_90119329	1.876	NM_016021	UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr10_+_99463468	1.858		MARVELD1	MARVEL domain containing 1
chr14_+_54102518	1.855		LOC644925	hypothetical LOC644925
chr16_-_87378872	1.853	NM_001142864	FAM38A	family with sequence similarity 38, member A
chr9_-_133605037	1.849		RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1
chr15_-_23235152	1.846	NM_130839	UBE3A	ubiquitin protein ligase E3A
chr1_+_9275542	1.843		SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr8_-_124622434	1.842	NM_058229	FBXO32	F-box protein 32

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	4.85e-26	GO:0009987	cellular process
1.17	4.53e-25	GO:0044237	cellular metabolic process
1.22	1.85e-23	GO:0044260	cellular macromolecule metabolic process
1.13	3.33e-17	GO:0008152	metabolic process
1.17	5.15e-17	GO:0043170	macromolecule metabolic process
1.14	1.81e-16	GO:0044238	primary metabolic process
1.26	5.64e-13	GO:0048523	negative regulation of cellular process
1.12	6.77e-12	GO:0050794	regulation of cellular process
1.23	9.12e-12	GO:0048519	negative regulation of biological process
1.21	2.30e-11	GO:0071841	cellular component organization or biogenesis at cellular level
1.21	3.54e-11	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	4.02e-11	GO:0016043	cellular component organization
1.21	4.02e-11	GO:0071842	cellular component organization at cellular level
1.18	4.81e-11	GO:0071840	cellular component organization or biogenesis
1.18	3.65e-10	GO:0034641	cellular nitrogen compound metabolic process
1.17	3.75e-10	GO:0031323	regulation of cellular metabolic process
1.18	3.95e-10	GO:0006807	nitrogen compound metabolic process
1.22	1.17e-09	GO:0090304	nucleic acid metabolic process
1.10	1.96e-09	GO:0050789	regulation of biological process
1.21	2.35e-09	GO:0048522	positive regulation of cellular process
1.20	3.23e-09	GO:0044267	cellular protein metabolic process
1.15	4.29e-09	GO:0019222	regulation of metabolic process
1.09	5.29e-09	GO:0065007	biological regulation
1.27	6.27e-09	GO:0009653	anatomical structure morphogenesis
1.25	1.27e-08	GO:0016070	RNA metabolic process
1.41	1.58e-08	GO:0007167	enzyme linked receptor protein signaling pathway
1.23	1.87e-08	GO:0043412	macromolecule modification
1.17	1.93e-08	GO:0060255	regulation of macromolecule metabolic process
1.16	2.04e-08	GO:0080090	regulation of primary metabolic process
1.33	3.18e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.23	3.20e-08	GO:0006464	protein modification process
1.18	4.87e-08	GO:0048518	positive regulation of biological process
1.31	1.27e-07	GO:0007049	cell cycle
1.34	2.29e-07	GO:0048699	generation of neurons
1.15	2.71e-07	GO:0032502	developmental process
1.15	4.98e-07	GO:0007275	multicellular organismal development
1.40	5.36e-07	GO:0010629	negative regulation of gene expression
1.43	7.06e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.31	9.64e-07	GO:0022008	neurogenesis
1.30	9.86e-07	GO:0009892	negative regulation of metabolic process
1.18	1.07e-06	GO:0044249	cellular biosynthetic process
1.36	1.21e-06	GO:0009790	embryo development
1.18	1.79e-06	GO:0010468	regulation of gene expression
1.24	1.90e-06	GO:0007399	nervous system development
1.23	2.07e-06	GO:0006996	organelle organization
1.31	2.25e-06	GO:0031324	negative regulation of cellular metabolic process
1.32	2.73e-06	GO:0022402	cell cycle process
1.32	3.77e-06	GO:0051128	regulation of cellular component organization
1.35	4.64e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.35	4.71e-06	GO:0009890	negative regulation of biosynthetic process
1.22	4.82e-06	GO:0034645	cellular macromolecule biosynthetic process
1.22	5.83e-06	GO:0009059	macromolecule biosynthetic process
1.20	7.64e-06	GO:0010467	gene expression
1.17	1.06e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.19	1.12e-05	GO:0030154	cell differentiation
1.21	1.47e-05	GO:0023051	regulation of signaling
1.36	1.49e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.38	1.56e-05	GO:0051253	negative regulation of RNA metabolic process
1.38	1.63e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.40	1.81e-05	GO:0000904	cell morphogenesis involved in differentiation
1.18	1.88e-05	GO:0048869	cellular developmental process
1.29	1.94e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.36	2.18e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	2.33e-05	GO:0009058	biosynthetic process
1.15	2.93e-05	GO:0019538	protein metabolic process
1.35	3.16e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.14	3.23e-05	GO:0048856	anatomical structure development
1.22	3.68e-05	GO:0009966	regulation of signal transduction
1.28	4.14e-05	GO:0048468	cell development
1.15	4.71e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.15	6.47e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	7.21e-05	GO:0032989	cellular component morphogenesis
1.34	8.95e-05	GO:0000902	cell morphogenesis
1.33	1.13e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.33	1.22e-04	GO:0030030	cell projection organization
1.40	1.51e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.17	1.69e-04	GO:0051252	regulation of RNA metabolic process
1.15	1.83e-04	GO:0031326	regulation of cellular biosynthetic process
1.40	1.98e-04	GO:0007409	axonogenesis
1.27	2.21e-04	GO:0006351	transcription, DNA-dependent
1.39	2.33e-04	GO:0048812	neuron projection morphogenesis
1.15	2.54e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.28	2.58e-04	GO:0033554	cellular response to stress
1.14	2.61e-04	GO:0048731	system development
1.36	3.07e-04	GO:0032990	cell part morphogenesis
1.23	3.53e-04	GO:0044248	cellular catabolic process
1.34	3.83e-04	GO:0048666	neuron development
1.36	3.88e-04	GO:0048858	cell projection morphogenesis
1.36	5.05e-04	GO:0031175	neuron projection development
1.30	5.14e-04	GO:0030182	neuron differentiation
1.14	5.65e-04	GO:0009889	regulation of biosynthetic process
1.53	5.82e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.26	6.79e-04	GO:0008219	cell death
1.23	6.92e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.21	7.97e-04	GO:0051641	cellular localization
1.26	8.26e-04	GO:0016265	death
1.27	9.46e-04	GO:0046907	intracellular transport
1.36	1.05e-03	GO:0072358	cardiovascular system development
1.36	1.05e-03	GO:0072359	circulatory system development
1.32	1.12e-03	GO:0000278	mitotic cell cycle
1.52	1.16e-03	GO:0045786	negative regulation of cell cycle
1.29	1.17e-03	GO:0022403	cell cycle phase
1.40	1.60e-03	GO:0043009	chordate embryonic development
1.45	1.65e-03	GO:0032446	protein modification by small protein conjugation
1.20	1.69e-03	GO:0033036	macromolecule localization
1.23	1.71e-03	GO:0008104	protein localization
2.60	2.09e-03	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
1.23	2.13e-03	GO:0032268	regulation of cellular protein metabolic process
1.28	2.16e-03	GO:0012501	programmed cell death
1.21	2.17e-03	GO:0031325	positive regulation of cellular metabolic process
1.30	2.20e-03	GO:0051726	regulation of cell cycle
1.39	2.22e-03	GO:0009792	embryo development ending in birth or egg hatching
1.15	2.40e-03	GO:0006355	regulation of transcription, DNA-dependent
1.46	2.64e-03	GO:0016567	protein ubiquitination
1.39	2.82e-03	GO:0048598	embryonic morphogenesis
1.10	3.22e-03	GO:0051716	cellular response to stimulus
1.23	3.23e-03	GO:0032774	RNA biosynthetic process
1.24	3.32e-03	GO:0050793	regulation of developmental process
1.19	3.83e-03	GO:0009056	catabolic process
1.38	3.97e-03	GO:0016568	chromatin modification
1.20	4.07e-03	GO:0009893	positive regulation of metabolic process
1.32	5.24e-03	GO:0044265	cellular macromolecule catabolic process
1.27	5.46e-03	GO:0006915	apoptosis
1.24	5.63e-03	GO:0045184	establishment of protein localization
1.40	6.47e-03	GO:0060284	regulation of cell development
1.24	7.63e-03	GO:0015031	protein transport
1.61	7.79e-03	GO:0008286	insulin receptor signaling pathway
1.38	8.11e-03	GO:0051301	cell division
1.27	9.15e-03	GO:0045595	regulation of cell differentiation
1.21	1.20e-02	GO:0051649	establishment of localization in cell
1.37	1.21e-02	GO:0044419	interspecies interaction between organisms
1.21	1.27e-02	GO:0051246	regulation of protein metabolic process
1.25	1.30e-02	GO:2000026	regulation of multicellular organismal development
1.28	1.37e-02	GO:0009057	macromolecule catabolic process
1.35	1.40e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.32	1.65e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.62	1.82e-02	GO:0007050	cell cycle arrest
1.25	2.28e-02	GO:0016192	vesicle-mediated transport
1.40	2.85e-02	GO:0010608	posttranscriptional regulation of gene expression
1.24	2.93e-02	GO:0031399	regulation of protein modification process
1.20	3.04e-02	GO:0010646	regulation of cell communication
1.39	3.13e-02	GO:0001944	vasculature development
1.77	3.15e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.36	3.68e-02	GO:0007411	axon guidance
1.40	4.15e-02	GO:0001568	blood vessel development
1.31	4.58e-02	GO:0060548	negative regulation of cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	5.49e-65	GO:0005622	intracellular
1.14	2.24e-63	GO:0044424	intracellular part
1.14	7.81e-44	GO:0043226	organelle
1.17	1.62e-43	GO:0005737	cytoplasm
1.14	1.82e-43	GO:0043229	intracellular organelle
1.16	8.50e-42	GO:0043227	membrane-bounded organelle
1.16	2.14e-41	GO:0043231	intracellular membrane-bounded organelle
1.20	4.70e-31	GO:0005634	nucleus
1.18	9.24e-27	GO:0044444	cytoplasmic part
1.17	1.46e-22	GO:0044446	intracellular organelle part
1.17	3.13e-22	GO:0044422	organelle part
1.30	1.55e-20	GO:0044428	nuclear part
1.29	3.57e-17	GO:0005829	cytosol
1.29	9.76e-16	GO:0031981	nuclear lumen
1.25	2.85e-14	GO:0070013	intracellular organelle lumen
1.24	1.12e-13	GO:0043233	organelle lumen
1.24	1.54e-13	GO:0031974	membrane-enclosed lumen
1.30	1.37e-11	GO:0005654	nucleoplasm
1.04	1.78e-11	GO:0044464	cell part
1.04	2.00e-11	GO:0005623	cell
1.19	2.19e-07	GO:0031090	organelle membrane
1.22	1.03e-06	GO:0012505	endomembrane system
1.72	1.51e-06	GO:0005912	adherens junction
1.32	1.79e-06	GO:0044451	nucleoplasm part
1.63	2.58e-05	GO:0070161	anchoring junction
1.14	4.29e-05	GO:0043228	non-membrane-bounded organelle
1.14	4.29e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.25	5.59e-05	GO:0005794	Golgi apparatus
1.73	1.63e-04	GO:0030055	cell-substrate junction
1.11	2.55e-04	GO:0032991	macromolecular complex
1.55	2.97e-04	GO:0031252	cell leading edge
1.93	3.38e-04	GO:0031256	leading edge membrane
1.71	5.52e-04	GO:0005924	cell-substrate adherens junction
1.12	8.51e-04	GO:0043234	protein complex
1.70	1.19e-03	GO:0005925	focal adhesion
1.27	3.94e-03	GO:0044431	Golgi apparatus part
1.99	7.21e-03	GO:0017053	transcriptional repressor complex
1.34	9.80e-03	GO:0005815	microtubule organizing center
1.29	1.07e-02	GO:0000139	Golgi membrane
1.39	1.76e-02	GO:0005635	nuclear envelope
1.27	1.83e-02	GO:0005730	nucleolus
1.40	2.65e-02	GO:0016604	nuclear body
1.92	2.72e-02	GO:0030173	integral to Golgi membrane
1.86	4.55e-02	GO:0031228	intrinsic to Golgi membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.17	9.58e-33	GO:0005515	protein binding
1.08	1.18e-24	GO:0005488	binding
1.31	1.74e-08	GO:0030528	transcription regulator activity
1.54	2.63e-07	GO:0008134	transcription factor binding
1.14	2.98e-06	GO:0003676	nucleic acid binding
1.26	1.29e-05	GO:0001071	nucleic acid binding transcription factor activity
1.26	1.29e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.16	3.29e-05	GO:0000166	nucleotide binding
1.40	1.63e-04	GO:0000988	protein binding transcription factor activity
1.40	1.63e-04	GO:0000989	transcription factor binding transcription factor activity
1.44	2.00e-04	GO:0016564	transcription repressor activity
1.39	2.31e-04	GO:0003712	transcription cofactor activity
1.27	2.76e-04	GO:0019899	enzyme binding
1.16	1.24e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.59	1.31e-03	GO:0003714	transcription corepressor activity
1.27	1.51e-03	GO:0043565	sequence-specific DNA binding
1.16	1.55e-03	GO:0017076	purine nucleotide binding
1.14	1.64e-03	GO:0003677	DNA binding
1.33	2.10e-03	GO:0019904	protein domain specific binding
1.15	2.24e-03	GO:0032553	ribonucleotide binding
1.15	2.24e-03	GO:0032555	purine ribonucleotide binding
1.40	2.87e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.17	5.01e-03	GO:0030554	adenyl nucleotide binding
1.08	5.61e-03	GO:0003824	catalytic activity
2.01	6.71e-03	GO:0046332	SMAD binding
1.16	6.80e-03	GO:0032559	adenyl ribonucleotide binding
1.40	6.97e-03	GO:0016881	acid-amino acid ligase activity
1.17	7.08e-03	GO:0005524	ATP binding
1.41	1.50e-02	GO:0019787	small conjugating protein ligase activity
1.35	1.88e-02	GO:0016563	transcription activator activity
1.28	3.06e-02	GO:0016874	ligase activity