Motif ID: TFEB.p2

Z-value: 1.899


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41811323-0.702.7e-03Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_27162688 6.642 NM_006896
 HOXA7
homeobox A7
chr5_+_34692124 6.034 NM_001145522
NM_015577
 RAI14

retinoic acid induced 14

chr5_+_34692239 4.999 RAI14
retinoic acid induced 14
chr5_+_34692352 4.893 NM_001145520
 RAI14
retinoic acid induced 14
chr15_-_71712711 4.571 NM_001161363
NM_001161364
NM_012428
NM_017455
 NPTN



neuroplastin



chr3_-_172109119 4.205 NM_020390
 EIF5A2
eukaryotic translation initiation factor 5A2
chr3_-_172109075 3.742 EIF5A2
eukaryotic translation initiation factor 5A2
chr13_-_20533703 3.735 NM_014572
 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr13_+_112999462 3.593 NM_005561
 LAMP1
lysosomal-associated membrane protein 1
chr6_+_87921980 3.509 NM_015021
 ZNF292
zinc finger protein 292
chr11_+_120399966 3.494 NM_001130047
NM_152715
 TBCEL

tubulin folding cofactor E-like

chr13_-_109236897 3.460 NM_003749
 IRS2
insulin receptor substrate 2
chr13_-_20533629 3.338 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr12_+_52653176 3.204 NM_014212
 HOXC11
homeobox C11
chr11_-_8849485 3.147 ST5
suppression of tumorigenicity 5
chr3_+_33293915 3.136 NM_012157
NM_001171713
 FBXL2

F-box and leucine-rich repeat protein 2

chr1_+_148521852 3.123 NM_144697
 C1orf51
chromosome 1 open reading frame 51
chr2_+_85834111 3.113 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr16_+_28893525 3.052 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
 SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr13_+_112999538 3.028 LAMP1
lysosomal-associated membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
7.14 1.19e-03 GO:0015682 ferric iron transport
7.14 1.19e-03 GO:0033572 transferrin transport
4.43 2.43e-02 GO:0048704 embryonic skeletal system morphogenesis
3.80 3.10e-02 GO:0048706 embryonic skeletal system development
1.95 4.80e-02 GO:0034613 cellular protein localization
1.77 3.17e-02 GO:0046907 intracellular transport
1.74 2.61e-02 GO:0015031 protein transport
1.73 3.61e-03 GO:0008104 protein localization
1.71 4.53e-02 GO:0045184 establishment of protein localization
1.61 1.26e-02 GO:0033036 macromolecule localization
1.59 3.00e-02 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
7.50 7.16e-03 GO:0033176 proton-transporting V-type ATPase complex
4.02 1.17e-02 GO:0031902 late endosome membrane
3.43 4.19e-05 GO:0005774 vacuolar membrane
3.41 2.53e-05 GO:0044437 vacuolar part
3.35 2.12e-03 GO:0005765 lysosomal membrane
3.19 1.04e-09 GO:0005773 vacuole
3.11 1.03e-02 GO:0005770 late endosome
2.98 4.23e-03 GO:0005769 early endosome
2.94 2.21e-06 GO:0000323 lytic vacuole
2.94 2.21e-06 GO:0005764 lysosome
2.42 5.12e-03 GO:0010008 endosome membrane
2.40 5.95e-03 GO:0044440 endosomal part
2.19 3.28e-04 GO:0005768 endosome
1.40 1.61e-02 GO:0044428 nuclear part
1.24 1.79e-03 GO:0044422 organelle part
1.24 2.80e-03 GO:0044446 intracellular organelle part
1.22 1.24e-02 GO:0005634 nucleus
1.21 1.31e-06 GO:0043227 membrane-bounded organelle
1.21 1.68e-06 GO:0043231 intracellular membrane-bounded organelle
1.21 5.79e-03 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
5.71 2.33e-02 GO:0019829 cation-transporting ATPase activity
1.72 4.93e-02 GO:0043565 sequence-specific DNA binding
1.19 5.81e-03 GO:0005515 protein binding