Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 3.440


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX3chr5_+_1706688920.371.6e-01Click!
TLX1chr10_+_1028810500.263.3e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_11585264 9.460 NM_001128221
 VGLL4
vestigial like 4 (Drosophila)
chr14_+_85066207 9.090 NM_013231
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr15_-_38420414 8.835 NM_207380
 C15orf52
chromosome 15 open reading frame 52
chr14_+_85066265 8.828 FLRT2
fibronectin leucine rich transmembrane protein 2
chr21_+_32706615 7.996 NM_058187
 C21orf63
chromosome 21 open reading frame 63
chr12_-_50871953 7.778 NM_001081492
NM_182507
 KRT80

keratin 80

chr7_-_27153892 7.302 NM_024014
 HOXA6
homeobox A6
chr7_+_22733626 7.098 IL6
interleukin 6 (interferon, beta 2)
chr1_-_151804929 6.692 NM_005978
 S100A2
S100 calcium binding protein A2
chr15_-_38417564 6.691 C15orf52
chromosome 15 open reading frame 52
chr7_+_115952279 6.440 NM_001172895
 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_115952325 6.125 CAV1
caveolin 1, caveolae protein, 22kDa
chr9_-_25668855 6.005 NM_001004125
 TUSC1
tumor suppressor candidate 1
chr5_+_150000394 5.884 NM_001109974
NM_007286
 SYNPO

synaptopodin

chr7_+_22733290 5.701 NM_000600
 IL6
interleukin 6 (interferon, beta 2)
chr5_+_38481392 5.652 NM_182801
 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr7_+_115952074 5.634 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa
chr12_+_64504408 5.208 NM_003483
NM_003484
 HMGA2

high mobility group AT-hook 2

chr1_-_171441234 5.197 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_13178327 5.091



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.47 2.58e-02 GO:0005887 integral to plasma membrane
1.46 3.24e-02 GO:0031226 intrinsic to plasma membrane
1.34 2.34e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.46 4.25e-02 GO:0008083 growth factor activity