Motif ID: TLX2.p2

Z-value: 1.228


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_74595073-0.514.5e-02Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_14266200 1.182 NM_013281
NM_198391
 FLRT3

fibronectin leucine rich transmembrane protein 3

chrX_-_73429101 1.054 MIR374AHG
mir-374a-545 cluster host gene (non-protein coding)
chr4_-_38534802 0.982 NM_006068
 TLR6
toll-like receptor 6
chr13_-_40491491 0.976 NM_172373
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_55269974 0.906


chr13_-_40491405 0.906 ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_-_62379788 0.829 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr3_+_69216747 0.812 NM_006407
 ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr12_+_14429499 0.777 ATF7IP
activating transcription factor 7 interacting protein
chr6_+_26548678 0.772 NM_006994
NM_197974
 BTN3A3

butyrophilin, subfamily 3, member A3

chr3_-_15814678 0.768 NM_001195098
 ANKRD28
ankyrin repeat domain 28
chr1_-_114925734 0.752 NM_005872
 BCAS2
breast carcinoma amplified sequence 2
chr10_-_46593923 0.742 NM_001040084
NM_001098845
 ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr9_-_124715392 0.734 NM_006626
 ZBTB6
zinc finger and BTB domain containing 6
chr22_-_35914200 0.732 NM_031910
NM_182486
 C1QTNF6

C1q and tumor necrosis factor related protein 6

chr10_+_86174665 0.720 FAM190B
family with sequence similarity 190, member B
chr4_-_35922288 0.693 NM_015230
 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_47216925 0.679 NM_001630
 ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr1_-_154837855 0.670 NM_015590
NM_182679
 GPATCH4

G patch domain containing 4

chr18_+_54013575 0.666 NM_001144970
 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.98 2.13e-03 GO:0019080 viral genome expression
2.98 2.13e-03 GO:0019083 viral transcription
2.76 1.57e-02 GO:0006415 translational termination
2.71 5.68e-03 GO:0006414 translational elongation
2.61 2.87e-02 GO:0043241 protein complex disassembly
2.61 2.87e-02 GO:0043624 cellular protein complex disassembly
2.50 2.74e-03 GO:0019058 viral infectious cycle
1.60 3.31e-02 GO:0071822 protein complex subunit organization
1.36 3.72e-03 GO:0010467 gene expression
1.20 1.47e-02 GO:0044260 cellular macromolecule metabolic process
1.15 3.20e-02 GO:0044238 primary metabolic process
1.10 1.01e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
5.89 6.38e-03 GO:0042613 MHC class II protein complex
3.90 2.12e-03 GO:0022625 cytosolic large ribosomal subunit
3.21 1.37e-03 GO:0015934 large ribosomal subunit
2.93 2.22e-03 GO:0022626 cytosolic ribosome
2.24 3.80e-03 GO:0044445 cytosolic part
2.24 4.43e-02 GO:0005765 lysosomal membrane
2.20 9.71e-04 GO:0005840 ribosome
1.56 4.19e-02 GO:0030529 ribonucleoprotein complex
1.37 1.93e-05 GO:0005829 cytosol
1.31 3.05e-05 GO:0043228 non-membrane-bounded organelle
1.31 3.05e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.27 9.05e-03 GO:0031974 membrane-enclosed lumen
1.27 1.13e-02 GO:0070013 intracellular organelle lumen
1.26 1.33e-02 GO:0043233 organelle lumen
1.21 1.89e-06 GO:0044446 intracellular organelle part
1.20 8.30e-06 GO:0044422 organelle part
1.20 2.33e-02 GO:0032991 macromolecular complex
1.17 1.53e-08 GO:0005737 cytoplasm
1.17 3.67e-04 GO:0044444 cytoplasmic part
1.11 8.19e-05 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.37 1.15e-03 GO:0003735 structural constituent of ribosome
1.15 8.93e-05 GO:0005515 protein binding