Motif ID: ZEB1.p2

Z-value: 3.702


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31650069-0.767.1e-04Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_22363036 7.892 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_40431359 7.552 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr19_+_40431618 7.311 LSR
lipolysis stimulated lipoprotein receptor
chr8_+_120289735 7.222 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr22_+_38720881 7.151 NM_138435
FAM83F
family with sequence similarity 83, member F
chr11_+_32808045 6.124 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr17_-_37196463 5.947 NM_002230
NM_021991
JUP

junction plakoglobin

chr19_+_40431122 5.603 LSR
lipolysis stimulated lipoprotein receptor
chr4_-_35922288 5.389 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_40431678 5.114 LSR
lipolysis stimulated lipoprotein receptor
chr8_-_144887876 5.039 NM_198488
FAM83H
family with sequence similarity 83, member H
chr1_-_27159462 5.032 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr1_-_208046011 4.871 NM_006147
IRF6
interferon regulatory factor 6
chr2_-_166358792 4.468 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_-_10527772 4.451 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_43447262 4.447 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_-_166358951 4.413 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr11_-_64368616 4.302 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr2_-_166359016 4.290 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_-_60587414 4.277 NM_001190764
LOC388564
hypothetical protein LOC388564

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.36 1.40e-02 GO:0044093 positive regulation of molecular function
1.29 4.78e-02 GO:0008104 protein localization
1.27 1.70e-02 GO:0033036 macromolecule localization
1.15 2.23e-02 GO:0051179 localization
1.12 1.21e-03 GO:0044237 cellular metabolic process
1.11 5.49e-04 GO:0008152 metabolic process
1.11 1.41e-02 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.31 3.92e-03 GO:0005794 Golgi apparatus
1.26 6.20e-04 GO:0012505 endomembrane system
1.22 4.09e-04 GO:0031090 organelle membrane
1.20 6.73e-03 GO:0005829 cytosol
1.16 3.26e-17 GO:0005737 cytoplasm
1.16 1.38e-08 GO:0044444 cytoplasmic part
1.14 3.23e-06 GO:0044446 intracellular organelle part
1.14 1.56e-05 GO:0044422 organelle part
1.08 7.53e-09 GO:0005622 intracellular
1.08 2.75e-08 GO:0044424 intracellular part
1.06 2.91e-02 GO:0043226 organelle
1.06 2.93e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.37 3.07e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.25 1.13e-03 GO:0016740 transferase activity
1.24 7.58e-04 GO:0017076 purine nucleotide binding
1.24 1.03e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.23 1.01e-03 GO:0032553 ribonucleotide binding
1.23 1.01e-03 GO:0032555 purine ribonucleotide binding
1.23 1.76e-02 GO:0005524 ATP binding
1.23 1.84e-02 GO:0030554 adenyl nucleotide binding
1.23 2.05e-02 GO:0032559 adenyl ribonucleotide binding
1.20 1.83e-03 GO:0000166 nucleotide binding
1.11 1.99e-05 GO:0005515 protein binding
1.10 4.35e-02 GO:0003824 catalytic activity