Motif ID: CDX1,2,4.p2

Z-value: 0.936


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
CDX1 1044 caudal type homeobox 1
CDX2 1045 caudal type homeobox 2
CDX4 1046 caudal type homeobox 4



Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_98757634 1.183 NM_004951
GPR183
G protein-coupled receptor 183
chr11_+_63060848 1.081 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr4_+_71806538 1.053 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr1_+_158975662 0.986 NM_021181
SLAMF7
SLAM family member 7
chr7_-_112513379 0.952 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr2_-_162808123 0.823 NM_004460
FAP
fibroblast activation protein, alpha
chr1_+_160868822 0.792 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr3_-_115585178 0.785 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chrX_-_33139349 0.756 NM_004006
DMD
dystrophin
chr5_+_53787187 0.714 NM_006308
HSPB3
heat shock 27kDa protein 3
chr7_-_13992351 0.710 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr1_+_194887630 0.654 NM_000186
NM_001014975
CFH

complement factor H

chr8_+_67201684 0.649 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr15_+_46957556 0.647 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr12_+_74160779 0.626 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr6_-_137536412 0.619 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr17_-_5078773 0.593 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr10_-_75085754 0.580 NM_001114133
SYNPO2L
synaptopodin 2-like
chr7_+_93862137 0.566 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr8_+_107807415 0.559 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr12_+_47584159 0.553 NM_033124
CCDC65
coiled-coil domain containing 65
chr3_-_171070314 0.552 NM_024727
LRRC31
leucine rich repeat containing 31
chr4_+_120167950 0.552 SYNPO2
synaptopodin 2
chr4_-_38460983 0.530 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr10_-_98021144 0.520 NM_001114094
NM_013314
BLNK

B-cell linker

chr19_+_14352920 0.513 CD97
CD97 molecule
chr4_+_120168002 0.508 SYNPO2
synaptopodin 2
chr22_-_43272567 0.492 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr1_-_245120900 0.490 AHCTF1
AT hook containing transcription factor 1
chr10_-_95231933 0.485 NM_013451
NM_133337
MYOF

myoferlin

chr2_+_161701711 0.480 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr5_+_40877053 0.479 NM_032587
CARD6
caspase recruitment domain family, member 6
chr19_-_44518516 0.475 NM_004877
GMFG
glia maturation factor, gamma
chr19_-_23733411 0.466 NM_138286
ZNF681
zinc finger protein 681
chr7_+_120416103 0.466 C7orf58
chromosome 7 open reading frame 58
chr5_-_64813459 0.462 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr9_+_78305368 0.449 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr5_-_124108672 0.439 NM_020747
ZNF608
zinc finger protein 608
chr7_-_92615593 0.435 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr1_+_160868932 0.427 DDR2
discoidin domain receptor tyrosine kinase 2
chr2_-_45648608 0.426 SRBD1
S1 RNA binding domain 1
chr12_+_53178834 0.420 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr12_-_51887266 0.419 NM_000889
ITGB7
integrin, beta 7
chr4_+_120167770 0.418 SYNPO2
synaptopodin 2
chr4_+_120167721 0.416 SYNPO2
synaptopodin 2
chr1_+_100957883 0.410 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr6_-_117853710 0.407 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr11_+_113671744 0.407 NM_006169
NNMT
nicotinamide N-methyltransferase
chr7_+_151284396 0.402 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr3_-_143230124 0.402 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr10_+_91051685 0.402 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr5_-_98290117 0.400 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr2_-_179623030 0.395 NM_173648
CCDC141
coiled-coil domain containing 141
chr12_-_51887318 0.392 ITGB7
integrin, beta 7
chr5_+_35892747 0.390 NM_002185
IL7R
interleukin 7 receptor
chr1_+_148747110 0.390 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr19_-_19793512 0.384 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr5_-_135318420 0.383 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr6_+_150304813 0.383 NM_025217
ULBP2
UL16 binding protein 2
chr8_+_38763911 0.383 TACC1
transforming, acidic coiled-coil containing protein 1
chr8_+_38763878 0.382 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr22_+_36008511 0.382 CYTH4
cytohesin 4
chr9_-_94338072 0.380 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr6_+_158990982 0.378 NM_001009991
SYTL3
synaptotagmin-like 3
chr1_-_197173159 0.377 LOC100131234
familial acute myelogenous leukemia related factor
chr11_+_46255737 0.376 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr11_+_6904167 0.372 NM_013250
ZNF215
zinc finger protein 215
chr9_+_102380156 0.371 NM_001018116
MURC
muscle-related coiled-coil protein
chr2_+_189547377 0.371 COL3A1
collagen, type III, alpha 1
chr3_+_150028130 0.369 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr4_-_177427252 0.367 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr19_+_14554895 0.366 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr9_+_5500544 0.358 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr1_+_84536636 0.356 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr6_+_149109841 0.354 NM_005715
UST
uronyl-2-sulfotransferase
chr6_+_29963328 0.351 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr3_-_106903734 0.336 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr4_-_153523113 0.331 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr7_-_112545847 0.330 LOC401397
hypothetical LOC401397
chr17_-_35975227 0.330 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_-_177378801 0.329 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr8_-_13416554 0.328 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr19_-_55539769 0.326 NAPSB
napsin B aspartic peptidase pseudogene
chr7_-_107930170 0.325 PNPLA8
patatin-like phospholipase domain containing 8
chr14_-_20098929 0.322 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_-_112545840 0.319 LOC401397
hypothetical LOC401397
chr3_-_15814678 0.315 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr1_+_242283129 0.309 NM_006352
ZNF238
zinc finger protein 238
chr4_+_47181987 0.306 NM_020453
ATP10D
ATPase, class V, type 10D
chr5_-_94442941 0.303 MCTP1
multiple C2 domains, transmembrane 1
chr1_-_24112345 0.302 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr1_-_77457664 0.301 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr14_+_87541220 0.300 NM_003608
GPR65
G protein-coupled receptor 65
chr14_-_93665678 0.299 NM_032036
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr5_+_140772691 0.298 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr19_-_58016696 0.297 NM_006969
ZNF28
zinc finger protein 28
chr9_+_126094067 0.296 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr17_-_31219943 0.296 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr15_-_78050515 0.295 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_-_67366807 0.294 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr12_+_45896318 0.288 NM_138371
FAM113B
family with sequence similarity 113, member B
chr17_-_3546047 0.286 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr10_+_111755715 0.285 NM_019903
ADD3
adducin 3 (gamma)
chr19_+_12036513 0.283 NM_001136501
ZNF844
zinc finger protein 844
chr5_-_156705250 0.281 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr19_-_56946911 0.280 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr9_+_74956614 0.278 ANXA1
annexin A1
chr6_+_116939500 0.277 NM_153711
FAM26E
family with sequence similarity 26, member E
chr21_+_29439768 0.273 C21orf7
chromosome 21 open reading frame 7
chr5_-_119768430 0.273


chr8_-_7207899 0.273 NM_001164457
ZNF705G
zinc finger protein 705G
chr2_-_217267742 0.271 IGFBP5
insulin-like growth factor binding protein 5
chr21_-_35174742 0.270 RUNX1
runt-related transcription factor 1
chr9_+_74956601 0.270 ANXA1
annexin A1
chr12_+_9713472 0.268 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr6_-_131333173 0.268 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr10_-_48426868 0.267 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr2_-_189752575 0.265 NM_000393
COL5A2
collagen, type V, alpha 2
chr4_+_169250281 0.265 NM_007193
ANXA10
annexin A10
chr1_-_168310232 0.265 NM_014970
KIFAP3
kinesin-associated protein 3
chr22_+_36008465 0.265 CYTH4
cytohesin 4
chr1_+_69998445 0.263 NM_020794
LRRC7
leucine rich repeat containing 7
chr11_+_113672407 0.262 NNMT
nicotinamide N-methyltransferase
chr19_-_62912347 0.260 NM_001085384
ZNF154
zinc finger protein 154
chr2_+_201182187 0.260 AOX1
aldehyde oxidase 1
chr1_+_190811479 0.259 NM_002922
RGS1
regulator of G-protein signaling 1
chrX_-_62487693 0.259 NM_001012968
SPIN4
spindlin family, member 4
chr5_+_132460779 0.258 HSPA4
heat shock 70kDa protein 4
chr4_-_122905731 0.256 NM_152399
TMEM155
transmembrane protein 155
chr10_+_70517823 0.255 NM_002727
SRGN
serglycin
chr17_+_3326045 0.252 NM_000049
ASPA
aspartoacylase
chr10_+_70517863 0.251 SRGN
serglycin
chr3_-_152449591 0.251 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr7_+_120416680 0.251 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr14_-_93665668 0.250 IFI27L2
interferon, alpha-inducible protein 27-like 2
chr5_+_162862808 0.248 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr1_-_195302973 0.248 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr2_-_175170674 0.248 WIPF1
WAS/WASL interacting protein family, member 1
chr7_+_134114912 0.247 CALD1
caldesmon 1
chr2_+_38009405 0.246 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr1_-_23393808 0.246 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr8_-_82522175 0.246 NM_002677
PMP2
peripheral myelin protein 2
chr16_+_27346079 0.244 NM_021798
IL21R
interleukin 21 receptor
chr12_-_101115677 0.243 NM_002674
PMCH
pro-melanin-concentrating hormone
chr18_+_148480 0.242 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chr20_+_31717964 0.242 NM_001024675
C20orf134
chromosome 20 open reading frame 134
chr8_+_70541631 0.241 SULF1
sulfatase 1
chr19_+_9347991 0.241 NM_001172651
ZNF177
zinc finger protein 177
chr9_+_74956494 0.241 NM_000700
ANXA1
annexin A1
chr5_+_121493113 0.241 NM_207317
ZNF474
zinc finger protein 474
chr3_+_158637273 0.240 NM_002852
PTX3
pentraxin 3, long
chr6_-_33085329 0.239 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chrX_+_100241453 0.238 NM_006733
CENPI
centromere protein I
chr14_-_57963620 0.238 TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr6_+_26070957 0.237 NM_006355
TRIM38
tripartite motif containing 38
chr22_+_21384862 0.237 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr16_+_79829794 0.236 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr21_-_30791298 0.236 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr4_-_130233855 0.236 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr12_-_90029672 0.236 NM_002345
LUM
lumican
chr5_-_75954807 0.235 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr14_+_57964462 0.235 NM_014749
KIAA0586
KIAA0586
chr17_-_3546108 0.234 P2RX5-TAX1BP3
P2RX5
P2RX5-TAX1BP3 read-through transcript
purinergic receptor P2X, ligand-gated ion channel, 5
chr4_-_186693574 0.234 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr15_-_68781662 0.233 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_27066749 0.231 NM_004264
MED21
mediator complex subunit 21
chr8_-_42742729 0.230 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr12_+_26096757 0.228 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr8_+_42671718 0.228 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr19_+_40895669 0.228 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr5_+_159368690 0.227 TTC1
tetratricopeptide repeat domain 1
chr1_-_143232526 0.226 FAM91A2
family with sequence similarity 91, member A2
chr4_+_154397975 0.226 TRIM2
tripartite motif containing 2
chr3_-_113701073 0.225 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr19_+_17253453 0.225 NM_152363
ANKLE1
ankyrin repeat and LEM domain containing 1
chr9_-_8723893 0.224 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr13_-_19008884 0.223 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr11_-_62668268 0.223 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr2_-_225519974 0.223 DOCK10
dedicator of cytokinesis 10
chr10_-_921694 0.222 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr1_-_27825178 0.222 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr10_+_80569464 0.222 ZMIZ1
zinc finger, MIZ-type containing 1
chr7_+_134114957 0.222 CALD1
caldesmon 1
chr11_-_76800525 0.222 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr13_-_32678142 0.221 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_134800533 0.221 LOC154092
hypothetical LOC154092
chr7_-_87687276 0.221 SRI
sorcin
chr15_-_43458247 0.219 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_177353707 0.219 NM_144644
SPATA4
spermatogenesis associated 4
chr4_+_41235077 0.218 LIMCH1
LIM and calponin homology domains 1
chr2_+_157822355 0.217 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_+_69314060 0.215 NM_198512
DGAT2L6
diacylglycerol O-acyltransferase 2-like 6
chr1_-_205210567 0.214 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr2_-_63518589 0.214 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr4_+_86918870 0.213 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr7_-_87687302 0.212 NM_003130
SRI
sorcin
chr11_-_121492010 0.212 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr5_+_118434966 0.209 NM_005509
DMXL1
Dmx-like 1
chr21_-_14840506 0.209 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_-_1701313 0.207 NM_001198994
NADK
NAD kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.98 5.75e-07 GO:0007606 sensory perception of chemical stimulus
2.01 1.63e-06 GO:0007608 sensory perception of smell
1.47 3.77e-04 GO:0002376 immune system process
1.57 3.01e-03 GO:0006955 immune response
1.51 8.41e-03 GO:0007600 sensory perception
1.14 1.77e-02 GO:0050896 response to stimulus
1.48 3.79e-02 GO:0006952 defense response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 9.81e-03 GO:0005886 plasma membrane
1.17 1.01e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.08 8.27e-08 GO:0004984 olfactory receptor activity
1.53 5.29e-04 GO:0004930 G-protein coupled receptor activity
1.34 1.39e-03 GO:0004872 receptor activity
1.40 1.41e-03 GO:0004888 transmembrane receptor activity
1.29 3.00e-03 GO:0004871 signal transducer activity
1.29 3.00e-03 GO:0060089 molecular transducer activity