Motif ID: HES1.p2

Z-value: 1.760


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)



Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_77094426 1.695 ACTG1
actin, gamma 1
chr5_+_75734759 1.612 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_-_50963942 1.556


chr9_-_125070613 1.474 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr20_-_62081434 1.421 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr19_+_34994701 1.394 NM_001238
CCNE1
cyclin E1
chr21_-_45786709 1.394 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr22_-_27405708 1.352 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr8_-_12657339 1.287 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr17_-_77094375 1.202 NM_001614
ACTG1
actin, gamma 1
chr20_-_62151216 1.159 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr15_+_39573363 1.067 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr1_-_45444812 1.060 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr17_+_37941476 1.059 NM_000263
NAGLU
N-acetylglucosaminidase, alpha
chr18_+_2836979 1.040 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr17_-_3814334 1.039 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr16_-_87244896 0.997 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr9_-_125070675 0.984 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr3_+_129690735 0.970


chr19_+_2240996 0.905


chr22_-_49311439 0.888 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr7_+_149651481 0.887 LRRC61
leucine rich repeat containing 61
chr7_-_149651594 0.886 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_+_149651202 0.884 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr7_-_23476156 0.875


chr1_+_9522107 0.869 NM_032315
SLC25A33
solute carrier family 25, member 33
chr22_+_40559070 0.869 SREBF2
sterol regulatory element binding transcription factor 2
chr3_-_127558747 0.862 NM_014079
KLF15
Kruppel-like factor 15
chr4_+_57469122 0.843 REST
RE1-silencing transcription factor
chr20_-_62081752 0.843 SAMD10
sterile alpha motif domain containing 10
chr1_+_226937732 0.833 RHOU
ras homolog gene family, member U
chr1_+_9522133 0.830 SLC25A33
solute carrier family 25, member 33
chr17_-_39757660 0.830 SLC25A39
solute carrier family 25, member 39
chr20_+_55399847 0.824 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr22_+_18091065 0.802 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr1_-_92124064 0.799 TGFBR3
transforming growth factor, beta receptor III
chr11_-_67153959 0.788 NM_181843
NUDT8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr6_+_111515341 0.783 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr19_-_1352474 0.781 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr20_-_61728866 0.781 GMEB2
glucocorticoid modulatory element binding protein 2
chr6_+_157722467 0.778 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr22_+_40559214 0.775 SREBF2
sterol regulatory element binding transcription factor 2
chr22_+_40559051 0.766 NM_004599
SREBF2
sterol regulatory element binding transcription factor 2
chr3_-_13436802 0.759 NM_024923
NUP210
nucleoporin 210kDa
chr16_+_65870641 0.758 PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr19_+_18391423 0.749


chr3_-_13436725 0.748 NUP210
nucleoporin 210kDa
chr12_+_6893751 0.747 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr10_+_92912676 0.744 PCGF5
polycomb group ring finger 5
chr17_+_37941790 0.736 NAGLU
N-acetylglucosaminidase, alpha
chr5_-_1547872 0.725 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr9_+_130491340 0.720 SET
SET nuclear oncogene
chr17_+_37941715 0.719 NAGLU
N-acetylglucosaminidase, alpha
chr18_+_586997 0.715 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr17_-_73636386 0.713 NM_001127198
TMC6
transmembrane channel-like 6
chr20_-_49592654 0.711 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr5_-_132194488 0.706 NM_001172700
SHROOM1
shroom family member 1
chr22_+_40559083 0.705 SREBF2
sterol regulatory element binding transcription factor 2
chr16_+_387176 0.696 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr17_-_73636362 0.687 TMC6
transmembrane channel-like 6
chr16_+_66153810 0.683 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr7_+_149696263 0.680 REPIN1
replication initiator 1
chr20_-_34635091 0.680


chr16_+_29725311 0.676 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr19_+_868285 0.675 NM_032551
KISS1R
KISS1 receptor
chr17_+_63799228 0.671 ARSG
arylsulfatase G
chr11_+_65414677 0.658 CCDC85B
coiled-coil domain containing 85B
chr6_-_43305156 0.654 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr22_-_17545872 0.651 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_10101081 0.645 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr19_-_8279157 0.645 NM_001165895
NM_016579
CD320

CD320 molecule

chr3_+_154035425 0.643 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr19_-_10474767 0.640 NM_203500
KEAP1
kelch-like ECH-associated protein 1
chr20_+_254205 0.639 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr17_-_77422526 0.638 ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr9_-_139316523 0.635 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr7_+_149696792 0.629 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr22_-_49311722 0.629 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr21_+_44109454 0.628 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_-_10475083 0.628 KEAP1
kelch-like ECH-associated protein 1
chr16_-_1369613 0.626 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr21_-_43368963 0.617 NM_000071
CBS
cystathionine-beta-synthase
chr9_-_85761451 0.612 C9orf64
chromosome 9 open reading frame 64
chr1_-_53566171 0.610 NM_001018054
NM_004631
NM_017522
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr10_-_95350949 0.600 NM_006744
RBP4
retinol binding protein 4, plasma
chr4_+_57468847 0.593 REST
RE1-silencing transcription factor
chr2_+_128175413 0.590 SFT2D3
SFT2 domain containing 3
chr1_+_165865953 0.584 NM_052862
RCSD1
RCSD domain containing 1
chr9_-_85761472 0.580 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr2_-_10506033 0.579 ODC1
ornithine decarboxylase 1
chr1_-_53566331 0.577 NM_033300
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_-_11042668 0.576 NM_003132
SRM
spermidine synthase
chr6_+_57145292 0.576 BAG2
BCL2-associated athanogene 2
chr20_+_34635362 0.575 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr17_+_43081837 0.571 KPNB1
karyopherin (importin) beta 1
chr10_-_60606195 0.571


chr20_-_61728774 0.570 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr1_-_210939727 0.568


chr6_+_34312906 0.565 HMGA1
high mobility group AT-hook 1
chr1_+_36046373 0.564 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr20_-_31737731 0.564 E2F1
E2F transcription factor 1
chr9_-_139084833 0.563 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr1_-_41480379 0.562 NM_001172218
NM_001172219
NM_001172220
NM_012236
SCMH1



sex comb on midleg homolog 1 (Drosophila)



chr4_+_1842833 0.559 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr20_+_34667624 0.555 C20orf24
chromosome 20 open reading frame 24
chr19_+_3310138 0.555 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr9_+_130491370 0.547 SET
SET nuclear oncogene
chr3_-_129690056 0.546 NM_001145661
GATA2
GATA binding protein 2
chr15_+_48261649 0.542 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr2_-_96351345 0.539


chr19_+_1055614 0.539 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr7_-_65084668 0.539 NM_000181
GUSB
glucuronidase, beta
chr2_+_10101822 0.536 NM_001177718
KLF11
Kruppel-like factor 11
chr2_+_242289983 0.535 NM_032329
ING5
inhibitor of growth family, member 5
chr19_-_2002222 0.534 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr6_-_35216981 0.532 NM_001093728
NM_018679
TCP11

t-complex 11 homolog (mouse)

chr22_+_40559053 0.528 SREBF2
sterol regulatory element binding transcription factor 2
chr6_+_34312667 0.528 HMGA1
high mobility group AT-hook 1
chr16_-_2330594 0.527 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr20_-_3102169 0.525 ProSAPiP1
ProSAPiP1 protein
chr6_-_125664913 0.524 NM_016063
HDDC2
HD domain containing 2
chr15_-_29950188 0.523 OTUD7A
OTU domain containing 7A
chr7_-_103417198 0.523 NM_005045
NM_173054
RELN

reelin

chr4_+_57468792 0.520 NM_005612
REST
RE1-silencing transcription factor
chr2_+_170298700 0.520 KLHL23
kelch-like 23 (Drosophila)
chr7_+_149696901 0.520 REPIN1
replication initiator 1
chr1_-_218168548 0.519 NM_018713
SLC30A10
solute carrier family 30, member 10
chr1_-_41480368 0.519 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr4_-_1232882 0.518 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chr17_-_77488258 0.517 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr3_+_128830656 0.516 NM_015720
PODXL2
podocalyxin-like 2
chr11_+_43920385 0.513 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr9_+_130491291 0.512 NM_003011
SET
SET nuclear oncogene
chr16_+_517834 0.511 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chr7_-_148212336 0.511 NM_004456
NM_152998
EZH2

enhancer of zeste homolog 2 (Drosophila)

chr2_+_203207912 0.510 FAM117B
family with sequence similarity 117, member B
chr9_-_138880530 0.508 NM_003792
NM_153200
EDF1

endothelial differentiation-related factor 1

chr5_+_133478252 0.507 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr16_+_65870481 0.506 NM_001129728
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr22_+_18484810 0.506 NM_002882
RANBP1
RAN binding protein 1
chr4_-_2233606 0.506 MXD4
MAX dimerization protein 4
chr21_+_44109529 0.505 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_-_11138760 0.504 NM_022068
FAM38B
family with sequence similarity 38, member B
chr22_-_37481857 0.503 NM_015374
SUN2
Sad1 and UNC84 domain containing 2
chr1_+_53698070 0.501 DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr17_+_75366524 0.500 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr11_+_279113 0.500 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr7_+_93977267 0.499 CASD1
CAS1 domain containing 1
chr1_-_32574185 0.496 NM_023009
MARCKSL1
MARCKS-like 1
chr11_-_67645246 0.496 CHKA
choline kinase alpha
chr19_+_10402334 0.494 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_935316 0.492 NM_024100
WDR18
WD repeat domain 18
chr9_-_125732005 0.490 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr16_+_1979959 0.489 NM_004209
SYNGR3
synaptogyrin 3
chr17_+_43374021 0.487 PNPO
pyridoxamine 5'-phosphate oxidase
chr22_-_37481925 0.482 SUN2
Sad1 and UNC84 domain containing 2
chr17_+_50698169 0.480 HLF
hepatic leukemia factor
chr7_-_150408785 0.478 FASTK
Fas-activated serine/threonine kinase
chr7_-_960897 0.477 ADAP1
ArfGAP with dual PH domains 1
chr1_-_1700088 0.477 NM_001198993
NADK
NAD kinase
chr10_+_92970302 0.476 NM_032373
PCGF5
polycomb group ring finger 5
chr1_+_153317887 0.475 NM_004952
EFNA3
ephrin-A3
chrX_-_18282698 0.473 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr20_+_48032918 0.473 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr19_-_10474266 0.472 NM_012289
KEAP1
kelch-like ECH-associated protein 1
chr7_-_148212310 0.471 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_+_99865189 0.467 NM_019606
MEPCE
methylphosphate capping enzyme
chr22_-_18807805 0.467 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr16_-_87300233 0.466 NM_001171815
RNF166
ring finger protein 166
chr7_-_148212312 0.465 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr20_-_61317891 0.464 NM_017798
YTHDF1
YTH domain family, member 1
chr16_-_1761710 0.461 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr3_+_38470782 0.461 NM_001106
ACVR2B
activin A receptor, type IIB
chr7_+_106472243 0.460 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr11_-_74740298 0.459 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr19_-_6453224 0.459 NM_006087
TUBB4
tubulin, beta 4
chr20_+_34667566 0.458 NM_018840
NM_199483
C20orf24

chromosome 20 open reading frame 24

chr5_-_132194122 0.454


chr4_-_1232742 0.454 CTBP1
C-terminal binding protein 1
chr6_-_119712596 0.454 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr2_-_6923215 0.453 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr8_+_144171271 0.452 LY6E
lymphocyte antigen 6 complex, locus E
chr6_+_37245860 0.452 NM_002648
PIM1
pim-1 oncogene
chr4_+_1842947 0.451 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_+_92970487 0.451 PCGF5
polycomb group ring finger 5
chr22_-_19686351 0.450 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr10_+_120779217 0.449 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr7_+_732831 0.449 NM_017802
HEATR2
HEAT repeat containing 2
chr16_+_65870891 0.449 NM_001129729
NM_001129731
PLEKHG4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

chr22_+_20101661 0.447 NM_015094
HIC2
hypermethylated in cancer 2
chr6_-_36518643 0.447 NM_152990
PXT1
peroxisomal, testis specific 1
chr6_+_36518521 0.447 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr8_+_144171275 0.447 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr6_-_143874463 0.446 NM_032020
FUCA2
fucosidase, alpha-L- 2, plasma
chr5_-_43075904 0.446 NM_001014279
C5orf39
chromosome 5 open reading frame 39
chr16_+_2465109 0.445 NM_020705
TBC1D24
TBC1 domain family, member 24
chr20_-_31725915 0.444 NM_031231
NM_031232
NECAB3

N-terminal EF-hand calcium binding protein 3

chr16_-_4604895 0.444 NM_145253
FAM100A
family with sequence similarity 100, member A
chr6_+_36518778 0.443 KCTD20
potassium channel tetramerisation domain containing 20
chr16_-_4341266 0.438 NM_016069
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 4.23e-16 GO:0044237 cellular metabolic process
1.18 1.63e-12 GO:0008152 metabolic process
1.34 2.15e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 2.86e-11 GO:0044238 primary metabolic process
1.25 3.00e-11 GO:0044260 cellular macromolecule metabolic process
1.31 5.72e-11 GO:0034641 cellular nitrogen compound metabolic process
1.36 7.52e-11 GO:0009058 biosynthetic process
1.30 1.06e-10 GO:0006807 nitrogen compound metabolic process
1.36 1.39e-10 GO:0044249 cellular biosynthetic process
1.10 4.13e-10 GO:0009987 cellular process
1.94 1.01e-08 GO:0016568 chromatin modification
1.71 1.27e-08 GO:0051276 chromosome organization
1.82 1.63e-08 GO:0006325 chromatin organization
1.31 5.09e-08 GO:0010468 regulation of gene expression
1.33 2.55e-07 GO:0090304 nucleic acid metabolic process
1.25 4.82e-07 GO:0060255 regulation of macromolecule metabolic process
1.19 8.63e-07 GO:0043170 macromolecule metabolic process
1.50 9.30e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 1.05e-06 GO:0019222 regulation of metabolic process
1.30 2.27e-06 GO:0051252 regulation of RNA metabolic process
1.23 3.05e-06 GO:0031323 regulation of cellular metabolic process
1.23 3.49e-06 GO:0080090 regulation of primary metabolic process
1.29 4.08e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.33 9.73e-06 GO:0006464 protein modification process
1.32 1.00e-05 GO:0043412 macromolecule modification
1.34 1.18e-05 GO:0016070 RNA metabolic process
1.26 1.54e-05 GO:0009889 regulation of biosynthetic process
1.26 1.69e-05 GO:0031326 regulation of cellular biosynthetic process
1.35 1.75e-05 GO:0006996 organelle organization
1.27 2.62e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.59 2.80e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 3.59e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.25 4.59e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 5.89e-05 GO:0050789 regulation of biological process
1.33 6.32e-05 GO:0034645 cellular macromolecule biosynthetic process
1.24 8.10e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.13 9.80e-05 GO:0050794 regulation of cellular process
1.28 1.03e-04 GO:0006355 regulation of transcription, DNA-dependent
1.32 1.03e-04 GO:0009059 macromolecule biosynthetic process
1.60 1.17e-04 GO:0051253 negative regulation of RNA metabolic process
2.05 1.23e-04 GO:0016569 covalent chromatin modification
1.56 1.34e-04 GO:0010629 negative regulation of gene expression
2.05 1.65e-04 GO:0016570 histone modification
1.11 3.33e-04 GO:0065007 biological regulation
1.53 3.34e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.58 3.97e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.43 5.05e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.24 7.26e-04 GO:0044267 cellular protein metabolic process
1.43 9.46e-04 GO:0006351 transcription, DNA-dependent
1.40 1.07e-03 GO:0009892 negative regulation of metabolic process
1.28 1.37e-03 GO:0010467 gene expression
1.48 1.67e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.49 1.82e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 2.17e-03 GO:0009890 negative regulation of biosynthetic process
1.37 3.38e-03 GO:0007049 cell cycle
1.38 3.92e-03 GO:0032774 RNA biosynthetic process
1.79 9.11e-03 GO:0032868 response to insulin stimulus
1.64 1.01e-02 GO:0043434 response to peptide hormone stimulus
1.22 1.03e-02 GO:0048519 negative regulation of biological process
1.38 1.27e-02 GO:0031324 negative regulation of cellular metabolic process
1.18 1.38e-02 GO:0016043 cellular component organization
1.55 1.59e-02 GO:0032583 regulation of gene-specific transcription
1.17 1.74e-02 GO:0071840 cellular component organization or biogenesis
1.56 2.91e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.60 3.62e-02 GO:0070647 protein modification by small protein conjugation or removal

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.01e-36 GO:0044424 intracellular part
1.16 1.04e-34 GO:0005622 intracellular
1.21 1.01e-29 GO:0043231 intracellular membrane-bounded organelle
1.21 1.25e-29 GO:0043227 membrane-bounded organelle
1.19 4.69e-28 GO:0043229 intracellular organelle
1.18 5.92e-28 GO:0043226 organelle
1.28 9.50e-23 GO:0005634 nucleus
1.44 7.41e-16 GO:0044428 nuclear part
1.22 1.54e-13 GO:0044446 intracellular organelle part
1.45 2.34e-13 GO:0031981 nuclear lumen
1.40 3.39e-13 GO:0070013 intracellular organelle lumen
1.39 3.67e-13 GO:0031974 membrane-enclosed lumen
1.15 6.06e-13 GO:0005737 cytoplasm
1.38 1.24e-12 GO:0043233 organelle lumen
1.21 2.30e-12 GO:0044422 organelle part
1.52 4.29e-12 GO:0005654 nucleoplasm
1.18 2.83e-10 GO:0044444 cytoplasmic part
1.05 6.74e-08 GO:0044464 cell part
1.05 7.15e-08 GO:0005623 cell
1.28 2.36e-05 GO:0005829 cytosol
1.49 2.49e-05 GO:0044451 nucleoplasm part
1.49 9.69e-04 GO:0005694 chromosome
1.30 1.49e-03 GO:0005739 mitochondrion
1.70 5.42e-03 GO:0000785 chromatin
1.15 1.80e-02 GO:0032991 macromolecular complex
3.64 2.01e-02 GO:0031519 PcG protein complex
1.43 2.79e-02 GO:0030529 ribonucleoprotein complex
1.45 2.84e-02 GO:0044427 chromosomal part
1.19 4.36e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.93e-15 GO:0005488 binding
1.32 1.71e-13 GO:0003676 nucleic acid binding
1.35 3.36e-10 GO:0003677 DNA binding
1.16 4.88e-10 GO:0005515 protein binding
1.38 2.17e-08 GO:0016740 transferase activity
1.18 7.26e-08 GO:0003824 catalytic activity
1.47 4.09e-07 GO:0030528 transcription regulator activity
1.82 6.31e-06 GO:0016564 transcription repressor activity
1.34 7.38e-06 GO:0032559 adenyl ribonucleotide binding
1.27 7.42e-06 GO:0000166 nucleotide binding
1.34 8.90e-06 GO:0030554 adenyl nucleotide binding
1.33 2.47e-05 GO:0005524 ATP binding
1.74 2.24e-04 GO:0008134 transcription factor binding
1.27 2.50e-04 GO:0032553 ribonucleotide binding
1.27 2.50e-04 GO:0032555 purine ribonucleotide binding
1.27 3.23e-04 GO:0017076 purine nucleotide binding
1.27 4.67e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.57 5.10e-04 GO:0016874 ligase activity
1.39 6.36e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.37 6.79e-04 GO:0001071 nucleic acid binding transcription factor activity
1.37 6.79e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.50 8.55e-04 GO:0042393 histone binding
1.66 1.22e-03 GO:0016563 transcription activator activity
1.16 1.48e-03 GO:0043167 ion binding
1.16 1.67e-03 GO:0043169 cation binding
1.16 2.18e-03 GO:0046872 metal ion binding
1.40 2.33e-03 GO:0016301 kinase activity
1.71 2.45e-03 GO:0016881 acid-amino acid ligase activity
1.67 2.52e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.23 3.30e-03 GO:0008270 zinc ion binding
1.41 4.05e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.38 4.83e-03 GO:0003723 RNA binding
1.82 5.16e-03 GO:0003682 chromatin binding
1.39 5.69e-03 GO:0019899 enzyme binding
1.52 6.54e-03 GO:0019904 protein domain specific binding
4.72 8.99e-03 GO:0042974 retinoic acid receptor binding
1.20 1.10e-02 GO:0046914 transition metal ion binding
5.03 1.36e-02 GO:0046965 retinoid X receptor binding
1.51 3.08e-02 GO:0003712 transcription cofactor activity
1.51 3.43e-02 GO:0000988 protein binding transcription factor activity
1.51 3.43e-02 GO:0000989 transcription factor binding transcription factor activity
1.78 4.68e-02 GO:0000287 magnesium ion binding
1.64 4.85e-02 GO:0019787 small conjugating protein ligase activity