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Motif ID: HIF1A.p2

Z-value: 1.816

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_38720881	2.033	NM_138435	FAM83F	family with sequence similarity 83, member F
chr10_-_88720908	1.811		LOC100133190	hypothetical LOC100133190
chr13_-_43259032	1.798	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr1_+_231816372	1.409	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr10_+_112247614	1.319	NM_004419	DUSP5	dual specificity phosphatase 5
chr1_+_13899272	1.260	NM_001135610	PRDM2	PR domain containing 2, with ZNF domain
chr3_-_180651874	1.231		GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_+_20341835	1.224	NM_001098520	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr11_+_12088639	1.206	NM_014632	MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2
chr11_+_20341806	1.172	NM_006410 NM_001098521	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr11_+_20341900	1.126	NM_001098522	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr3_-_180652024	1.124	NM_021629	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr4_+_321607	1.095		ZNF141	zinc finger protein 141
chr19_-_53516962	1.089		CCDC114	coiled-coil domain containing 114
chr4_+_321587	1.077	NM_003441	ZNF141	zinc finger protein 141
chr6_+_73388713	1.054		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr1_+_231816540	1.052		KCNK1	potassium channel, subfamily K, member 1
chr11_+_94141151	0.985	NM_130847	AMOTL1	angiomotin like 1
chr10_+_3099708	0.962	NM_002627	PFKP	phosphofructokinase, platelet
chr6_+_33697023	0.956	NM_002224	ITPR3	inositol 1,4,5-triphosphate receptor, type 3
chr5_+_49998677	0.945		PARP8	poly (ADP-ribose) polymerase family, member 8
chr10_-_43390014	0.933	NM_001099282 NM_001099283 NM_001099284	ZNF239	zinc finger protein 239
chr3_-_129024665	0.926	NM_001003794	MGLL	monoglyceride lipase
chr19_-_51608665	0.899	NM_032040	CCDC8	coiled-coil domain containing 8
chr1_+_148521852	0.894	NM_144697	C1orf51	chromosome 1 open reading frame 51
chr12_+_129922589	0.889		RAN	RAN, member RAS oncogene family
chr4_-_10068055	0.876	NM_053042	ZNF518B	zinc finger protein 518B
chrX_+_16714452	0.869	NM_001168683 NM_018360	TXLNG	taxilin gamma
chr3_-_129023850	0.857	NM_007283	MGLL	monoglyceride lipase
chr12_+_129922570	0.857		RAN	RAN, member RAS oncogene family
chr21_+_25856311	0.852		MIR155HG	MIR155 host gene (non-protein coding)
chr17_-_7996409	0.850	NM_002616	PER1	period homolog 1 (Drosophila)
chrX_-_47394808	0.847		ELK1	ELK1, member of ETS oncogene family
chr8_+_95722448	0.840		ESRP1	epithelial splicing regulatory protein 1
chr2_-_235070431	0.836	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr4_+_183302105	0.814		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr1_-_158161877	0.814		TAGLN2	transgelin 2
chr11_+_13646806	0.810		FAR1	fatty acyl CoA reductase 1
chrX_-_47394937	0.806	NM_001114123 NM_005229	ELK1	ELK1, member of ETS oncogene family
chr2_-_225615556	0.802	NM_014689	DOCK10	dedicator of cytokinesis 10
chr1_-_158161902	0.802	NM_003564	TAGLN2	transgelin 2
chrX_-_135161185	0.784	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr11_-_124871258	0.777	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_208046011	0.775	NM_006147	IRF6	interferon regulatory factor 6
chr19_-_19599973	0.772	NM_004720	LPAR2	lysophosphatidic acid receptor 2
chr11_+_13646727	0.770	NM_032228	FAR1	fatty acyl CoA reductase 1
chrX_-_13866366	0.767
chr19_-_63550712	0.763		A1BG	alpha-1-B glycoprotein
chr7_+_115637795	0.758	NM_015641	TES	testis derived transcript (3 LIM domains)
chr5_+_17270781	0.758		BASP1	brain abundant, membrane attached signal protein 1
chr1_+_12046020	0.750	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr9_-_109291575	0.748		KLF4	Kruppel-like factor 4 (gut)
chr1_-_35957030	0.715		C1orf216	chromosome 1 open reading frame 216
chr3_-_185025989	0.710	NM_024871	MAP6D1	MAP6 domain containing 1
chr17_-_58877276	0.710	NM_001017916 NM_001915	CYB561	cytochrome b-561
chr11_+_69602055	0.706	NM_018043	ANO1	anoctamin 1, calcium activated chloride channel
chr5_+_110587546	0.700	NM_001744	CAMK4	calcium/calmodulin-dependent protein kinase IV
chr12_-_21701985	0.694	NM_001174097	LDHB	lactate dehydrogenase B
chrX_+_148430424	0.692	NM_001171907 NM_001171908 NM_178124	CXorf40A	chromosome X open reading frame 40A
chr5_-_159730196	0.690	NM_031908	C1QTNF2	C1q and tumor necrosis factor related protein 2
chr9_-_109291866	0.687	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr1_+_222870573	0.687		CNIH3	cornichon homolog 3 (Drosophila)
chr12_+_68923043	0.684	NM_014515	CNOT2	CCR4-NOT transcription complex, subunit 2
chr12_-_21702036	0.683		LDHB	lactate dehydrogenase B
chrX_+_135057202	0.682	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr12_-_21702021	0.679		LDHB	lactate dehydrogenase B
chrX_+_64804235	0.669	NM_002444	MSN	moesin
chr10_+_17312654	0.669		VIM	vimentin
chr12_-_75983329	0.660	NM_203394	E2F7	E2F transcription factor 7
chr15_+_46957556	0.657	NM_014335	EID1	EP300 interacting inhibitor of differentiation 1
chr1_-_35956979	0.651		C1orf216	chromosome 1 open reading frame 216
chr3_+_23219707	0.649	NM_152653	UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr7_+_2525922	0.647	NM_001040167 NM_001040168	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_38905053	0.644	NM_198578	LRRK2	leucine-rich repeat kinase 2
chr16_-_30504309	0.644	NM_152458	ZNF785	zinc finger protein 785
chr12_-_21702000	0.641		LDHB	lactate dehydrogenase B
chr5_+_3649167	0.640	NM_024337	IRX1	iroquois homeobox 1
chr6_+_56927665	0.640	NM_152731	BEND6	BEN domain containing 6
chr3_-_16530132	0.638	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr1_-_173428455	0.638	NM_001162895 NM_014656 NM_001162893 NM_001162894	KIAA0040	KIAA0040
chr6_+_56927882	0.632		BEND6	BEN domain containing 6
chrX_-_148430250	0.630		LOC100131434	hypothetical LOC100131434
chr17_-_44010543	0.627	NM_024015	HOXB4	homeobox B4
chrX_-_13866451	0.626		GPM6B	glycoprotein M6B
chr13_-_35818491	0.623		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr18_+_42167904	0.619		RNF165	ring finger protein 165
chr13_-_35818777	0.615	NM_001142295	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr3_-_16529996	0.612		RFTN1	raftlin, lipid raft linker 1
chr3_-_73756668	0.609	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr2_-_96174502	0.602		DUSP2	dual specificity phosphatase 2
chr9_-_21984414	0.597	NM_058195	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr3_+_23219490	0.594		UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr4_-_119493322	0.593	NM_003619	PRSS12	protease, serine, 12 (neurotrypsin, motopsin)
chr1_+_222870798	0.591	NM_152495	CNIH3	cornichon homolog 3 (Drosophila)
chr13_-_35818396	0.587		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr14_-_87529222	0.587		GALC	galactosylceramidase
chr8_+_26296439	0.586	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr7_-_72609957	0.585	NM_001197244 NM_001707	BCL7B	B-cell CLL/lymphoma 7B
chr2_+_190981257	0.581	NM_017694	MFSD6	major facilitator superfamily domain containing 6
chr12_-_21702046	0.576	NM_002300	LDHB	lactate dehydrogenase B
chr17_-_40263124	0.576	NM_005497	GJC1	gap junction protein, gamma 1, 45kDa
chr14_-_87529212	0.574		GALC	galactosylceramidase
chr1_-_180840016	0.574	NM_002928	RGS16	regulator of G-protein signaling 16
chr2_-_213724577	0.572	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr2_-_96174865	0.570	NM_004418	DUSP2	dual specificity phosphatase 2
chr1_+_117253882	0.560	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr13_-_35818603	0.559	NM_001142296 NM_015087	SPG20	spastic paraplegia 20 (Troyer syndrome)
chrX_+_64804259	0.559		MSN	moesin
chr4_-_122063118	0.558	NM_018699	PRDM5	PR domain containing 5
chr22_-_30016707	0.555		PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr1_-_84237316	0.553	NM_024686	TTLL7	tubulin tyrosine ligase-like family, member 7
chr1_-_8861278	0.552		ENO1	enolase 1, (alpha)
chrX_-_13866565	0.547	NM_001001994	GPM6B	glycoprotein M6B
chr3_-_52065130	0.546	NM_001947	DUSP7	dual specificity phosphatase 7
chr15_+_61356801	0.545	NM_001145646 NM_031301	APH1B	anterior pharynx defective 1 homolog B (C. elegans)
chr22_+_16020241	0.545		CECR4	cat eye syndrome chromosome region, candidate 4 (non-protein coding)
chr8_+_22479115	0.539	NM_001018003	SORBS3	sorbin and SH3 domain containing 3
chr2_-_144991386	0.538		ZEB2	zinc finger E-box binding homeobox 2
chr1_+_181025494	0.538		NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr8_+_49083522	0.537	NM_003350	UBE2V2	ubiquitin-conjugating enzyme E2 variant 2
chr12_+_52806103	0.535		LOC400043	hypothetical LOC400043
chr1_+_199975563	0.535	NM_001167738	NAV1	neuron navigator 1
chr7_-_72609804	0.534		BCL7B	B-cell CLL/lymphoma 7B
chr4_-_143987053	0.532	NM_001101669 NM_003866	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_-_148430357	0.532		LOC100131434	hypothetical LOC100131434
chr11_-_66092534	0.526	NM_003793	CTSF	cathepsin F
chr2_+_74502364	0.526	NM_032118	WDR54	WD repeat domain 54
chr17_-_8000362	0.517		PER1	period homolog 1 (Drosophila)
chr15_-_81744469	0.516	NM_001717	BNC1	basonuclin 1
chr6_-_121697305	0.513	NM_152730	C6orf170	chromosome 6 open reading frame 170
chr7_+_27102197	0.510
chr3_-_36961539	0.509	NM_014831	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1
chr5_+_176493488	0.507		NSD1	nuclear receptor binding SET domain protein 1
chr5_+_17270474	0.503	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr7_+_39739690	0.492		NCRNA00265	non-protein coding RNA 265
chr7_+_48041632	0.490	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr10_+_80740584	0.489		ZMIZ1	zinc finger, MIZ-type containing 1
chr7_+_154720547	0.487		INSIG1	insulin induced gene 1
chr14_+_104523660	0.486	NM_174891	C14orf79	chromosome 14 open reading frame 79
chr1_-_146398501	0.484		LOC100286793 FLJ39739	hypothetical LOC100286793 hypothetical FLJ39739
chr19_-_11352850	0.477		EPOR	erythropoietin receptor
chr8_-_9046460	0.477		PPP1R3B	protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr19_-_36531958	0.473	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr8_+_94998258	0.468	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr18_+_54682261	0.465		ZNF532	zinc finger protein 532
chr8_+_145718702	0.464
chr9_-_139316523	0.458	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr9_+_90193058	0.456	NM_006717	SPIN1	spindlin 1
chr3_+_114414064	0.456	NM_033254	BOC	Boc homolog (mouse)
chr16_+_88169612	0.454	NM_014427 NM_153636	CPNE7	copine VII
chr6_+_1336077	0.452
chr5_+_148717806	0.449		PCYOX1L	prenylcysteine oxidase 1 like
chr9_+_132874324	0.448	NM_006059	LAMC3	laminin, gamma 3
chr19_+_43502380	0.447		KCNK6	potassium channel, subfamily K, member 6
chr8_-_72918697	0.446		MSC	musculin
chr8_-_124123772	0.445	NM_001134671 NM_024295	DERL1	Der1-like domain family, member 1
chr7_+_55054416	0.442		EGFR	epidermal growth factor receptor
chr5_-_127447197	0.441		FLJ33630	hypothetical LOC644873
chr7_-_87687302	0.441	NM_003130	SRI	sorcin
chr1_+_182622987	0.441		C1orf21	chromosome 1 open reading frame 21
chr22_-_22511173	0.438	NM_001002862 NM_001135751 NM_198440	DERL3	Der1-like domain family, member 3
chr8_+_98725505	0.437	NM_178812	MTDH	metadherin
chr3_-_81893308	0.437		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr18_+_40513889	0.437	NM_001130110	SETBP1	SET binding protein 1
chr5_+_176493233	0.435	NM_022455	NSD1	nuclear receptor binding SET domain protein 1
chr1_-_68071635	0.435	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr16_-_79395379	0.434	NM_152342	CDYL2	chromodomain protein, Y-like 2
chrX_+_101267315	0.434	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr5_+_148717762	0.433	NM_024028	PCYOX1L	prenylcysteine oxidase 1 like
chr9_-_21984379	0.432		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_-_84961749	0.428	NM_001080824	C2orf89	chromosome 2 open reading frame 89
chr7_+_44802691	0.423	NM_021130	PPIA	peptidylprolyl isomerase A (cyclophilin A)
chr9_+_111582317	0.422	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr1_-_143232344	0.419		LOC728855	hypothetical LOC728855
chr8_-_124123707	0.418		DERL1	Der1-like domain family, member 1
chr1_-_158161898	0.418		TAGLN2	transgelin 2
chr6_-_116799548	0.417		LOC100287467	hypothetical LOC100287467
chrX_+_11686198	0.417	NM_078628 NM_078629	MSL3	male-specific lethal 3 homolog (Drosophila)
chr20_-_57015698	0.417	NM_001336	CTSZ	cathepsin Z
chr1_-_8861374	0.415		ENO1	enolase 1, (alpha)
chr3_-_109292444	0.414	NM_001777 NM_198793	CD47	CD47 molecule
chr9_+_81376666	0.412	NM_007005	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr22_+_48971067	0.410		TRABD	TraB domain containing
chr11_+_65357972	0.409	NM_152760	SNX32	sorting nexin 32
chr8_-_116750277	0.408	NM_014112	TRPS1	trichorhinophalangeal syndrome I
chr1_+_207915617	0.408		G0S2	G0/G1switch 2
chr1_-_143232464	0.408
chrX_+_64804318	0.408		MSN	moesin
chr11_+_32069183	0.407		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr14_-_87529600	0.405	NM_000153 NM_001037525	GALC	galactosylceramidase
chr13_-_98536640	0.405	NM_001130049 NM_015296	DOCK9	dedicator of cytokinesis 9
chr8_-_124123721	0.404		DERL1	Der1-like domain family, member 1
chr6_-_97391779	0.403	NM_001143957 NM_030784	GPR63	G protein-coupled receptor 63
chr5_+_148941228	0.403	NM_001001669	ARHGEF37	Rho guanine nucleotide exchange factor (GEF) 37
chr7_-_27102049	0.402	NM_005522 NM_153620	HOXA1	homeobox A1
chr7_-_87687276	0.400		SRI	sorcin
chr2_-_217267742	0.398		IGFBP5	insulin-like growth factor binding protein 5
chr8_-_101804114	0.396		PABPC1	poly(A) binding protein, cytoplasmic 1
chr1_-_35957314	0.396	NM_152374	C1orf216	chromosome 1 open reading frame 216
chr2_+_222997456	0.396		SGPP2	sphingosine-1-phosphate phosphatase 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.45	1.35e-04	GO:0006913	nucleocytoplasmic transport
2.42	1.91e-04	GO:0051169	nuclear transport
1.22	5.35e-04	GO:0044260	cellular macromolecule metabolic process
1.15	1.32e-02	GO:0044237	cellular metabolic process
1.58	2.37e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.30	4.54e-02	GO:0043412	macromolecule modification

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	2.12e-14	GO:0044424	intracellular part
1.13	1.86e-13	GO:0005622	intracellular
1.15	7.47e-08	GO:0043231	intracellular membrane-bounded organelle
1.15	1.00e-07	GO:0043227	membrane-bounded organelle
1.13	4.03e-07	GO:0043226	organelle
1.13	6.43e-07	GO:0043229	intracellular organelle
1.21	9.77e-07	GO:0005634	nucleus
1.14	4.84e-06	GO:0005737	cytoplasm
2.15	4.90e-05	GO:0005635	nuclear envelope
1.05	1.91e-04	GO:0044464	cell part
1.05	1.98e-04	GO:0005623	cell
1.15	1.14e-03	GO:0044444	cytoplasmic part
1.30	2.16e-03	GO:0005829	cytosol
1.28	6.07e-03	GO:0044428	nuclear part
2.16	1.35e-02	GO:0031965	nuclear membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	3.23e-03	GO:0005515	protein binding
1.07	4.83e-03	GO:0005488	binding
1.29	3.67e-02	GO:0016740	transferase activity
1.25	3.88e-02	GO:0000166	nucleotide binding
1.20	4.09e-02	GO:0003676	nucleic acid binding