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Motif ID: HOXA9_MEIS1.p2

Z-value: 1.511

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_29597965	3.179		QPRT	quinolinate phosphoribosyltransferase
chr18_+_9875722	2.965	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chr1_+_196874839	2.468		PTPRC	protein tyrosine phosphatase, receptor type, C
chr15_+_42815851	2.080	NM_080745 NM_182985	TRIM69	tripartite motif containing 69
chr16_+_29597829	1.931	NM_014298	QPRT	quinolinate phosphoribosyltransferase
chr4_-_40211324	1.818		RBM47	RNA binding motif protein 47
chr9_-_99740243	1.490	NM_197978	HEMGN	hemogen
chr2_+_68445821	1.392	NM_002664	PLEK	pleckstrin
chr6_-_25044156	1.355		FAM65B	family with sequence similarity 65, member B
chr1_+_144152864	1.311		TXNIP	thioredoxin interacting protein
chr1_+_196874867	1.286		PTPRC	protein tyrosine phosphatase, receptor type, C
chrX_-_130792297	1.233		LOC286467	hypothetical LOC286467
chr1_+_196874759	1.165	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr4_+_123311207	1.079	NM_015312	KIAA1109	KIAA1109
chr7_+_72883128	1.047	NM_001305	CLDN4	claudin 4
chr19_+_61624	1.015	NM_001005240	OR4F4 OR4F17	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 17
chr3_-_173723754	1.003	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr1_-_611896	1.002	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr12_-_107551783	0.989	NM_003006	SELPLG	selectin P ligand
chr10_+_70517823	0.954	NM_002727	SRGN	serglycin
chr1_+_58899	0.868	NM_001005484	OR4F4 OR4F5	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 5
chr1_+_357502	0.862	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr6_+_29382381	0.859	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr15_+_64481270	0.845		MAP2K1	mitogen-activated protein kinase kinase 1
chr7_+_143457083	0.824	NM_001001659	OR2A14	olfactory receptor, family 2, subfamily A, member 14
chr1_-_157313179	0.823	NM_004833	AIM2	absent in melanoma 2
chr8_-_107023	0.822	NM_001005504	OR4F21	olfactory receptor, family 4, subfamily F, member 21
chr12_-_101115677	0.817	NM_002674	PMCH	pro-melanin-concentrating hormone
chr2_+_169631777	0.817	NM_199204	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr1_-_200397300	0.808		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr12_-_49708279	0.802	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_-_148854503	0.792
chr2_+_68445936	0.782		PLEK	pleckstrin
chr4_+_39084936	0.758		KLB	klotho beta
chr15_-_100280784	0.733	NM_001004195	OR4F4 OR4F17	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 17
chr1_-_167822248	0.729		F5	coagulation factor V (proaccelerin, labile factor)
chr22_-_25205376	0.720	NM_152841	HPS4	Hermansky-Pudlak syndrome 4
chr15_-_56093477	0.716	NM_170697	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr11_-_62145952	0.704	NM_012200	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr1_-_153477511	0.689		GBA	glucosidase, beta, acid
chr12_-_107551694	0.658		SELPLG	selectin P ligand
chr4_+_39084867	0.655	NM_175737	KLB	klotho beta
chr20_-_44575599	0.643	NM_018102 NM_199441	ZNF334	zinc finger protein 334
chr11_+_63627816	0.639	NM_013280	FLRT1	fibronectin leucine rich transmembrane protein 1
chr3_+_123279439	0.632	NM_006889	CD86	CD86 molecule
chr17_-_35464414	0.602	NM_001079518 NM_014815	MED24	mediator complex subunit 24
chr17_+_53587492	0.594	NM_012374	OR4D1	olfactory receptor, family 4, subfamily D, member 1
chr12_-_9159780	0.593		A2M	alpha-2-macroglobulin
chr14_-_93926679	0.586	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_49712483	0.574	NM_000324	RHAG	Rh-associated glycoprotein
chr18_+_2645885	0.564	NM_015295	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1
chr13_+_51334117	0.536	NM_031290	CCDC70	coiled-coil domain containing 70
chr11_-_4675524	0.531	NM_030774	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr2_-_165133239	0.511		GRB14	growth factor receptor-bound protein 14
chr1_+_938709	0.510	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr12_+_7348194	0.508	NM_001080454	ACSM4	acyl-CoA synthetase medium-chain family member 4
chr6_-_32665409	0.501	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr7_+_104468614	0.500		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr15_-_23204887	0.493	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr12_-_107551744	0.492		SELPLG	selectin P ligand
chr6_+_35308605	0.487		SCUBE3	signal peptide, CUB domain, EGF-like 3
chr1_-_167822334	0.484	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr7_+_115650240	0.466	NM_152829	TES	testis derived transcript (3 LIM domains)
chr14_+_77939845	0.464	NM_004796	NRXN3	neurexin 3
chrX_-_131181141	0.460		RAP2C	RAP2C, member of RAS oncogene family
chr7_+_128365482	0.457	NM_032643	IRF5	interferon regulatory factor 5
chr20_+_5935897	0.453	NM_001127458	CRLS1	cardiolipin synthase 1
chr1_+_67404756	0.433	NM_144701	IL23R	interleukin 23 receptor
chr18_+_70317548	0.417		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr10_+_70517863	0.414		SRGN	serglycin
chrX_-_105169370	0.406	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr4_-_83566802	0.404		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr1_-_245237925	0.401		ZNF695	zinc finger protein 695
chr12_-_51629874	0.383		KRT8	keratin 8
chr1_-_245237977	0.382	NM_020394	ZNF695	zinc finger protein 695
chr2_-_135498716	0.379	NM_001018046 NM_025052	YSK4	YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
chrX_-_77469635	0.378	NM_006639	CYSLTR1	cysteinyl leukotriene receptor 1
chr3_-_139960874	0.375	NM_006219	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide
chr6_+_31782618	0.369	NM_001003693	LY6G6F	lymphocyte antigen 6 complex, locus G6F
chr12_-_9159742	0.365		A2M	alpha-2-macroglobulin
chr14_+_19473606	0.356	NM_001004063	OR4K1	olfactory receptor, family 4, subfamily K, member 1
chr6_-_25940247	0.355	NM_005074	SLC17A1	solute carrier family 17 (sodium phosphate), member 1
chr1_+_13903936	0.343	NM_012231 NM_015866	PRDM2	PR domain containing 2, with ZNF domain
chr1_-_153477673	0.337	NM_001171812 NM_000157	GBA	glucosidase, beta, acid
chr6_+_28032997	0.328	NM_012367	OR2B6	olfactory receptor, family 2, subfamily B, member 6
chr11_+_5862076	0.319	NM_001005165	OR52E4	olfactory receptor, family 52, subfamily E, member 4
chr19_+_44681443	0.316		DLL3	delta-like 3 (Drosophila)
chr17_-_36444626	0.315	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr2_-_74634569	0.309	NM_032603	LOXL3	lysyl oxidase-like 3
chr12_+_61645361	0.309		RPL14	ribosomal protein L14
chr17_-_39094787	0.291	NM_001040002	MEOX1	mesenchyme homeobox 1
chr7_-_84589182	0.291	NM_152754	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr3_+_112743729	0.291		CD96	CD96 molecule
chr19_+_10689725	0.283	NM_001005360 NM_001005361 NM_001005362 NM_001190716 NM_004945	DNM2	dynamin 2
chr12_-_85756766	0.281	NM_013244	MGAT4C	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_93172119	0.278
chr22_+_21393107	0.274		IGLJ3	immunoglobulin lambda joining 3
chr19_+_44681374	0.273	NM_016941 NM_203486	DLL3	delta-like 3 (Drosophila)
chr15_+_36776090	0.271	NM_207444	C15orf53	chromosome 15 open reading frame 53
chr1_-_167865973	0.267	NM_003005	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
chrX_+_123062143	0.263		STAG2	stromal antigen 2
chr11_-_5964790	0.262	NM_001005173	OR52L1	olfactory receptor, family 52, subfamily L, member 1
chr17_-_26665194	0.260		EVI2B	ecotropic viral integration site 2B
chr4_+_71713324	0.258	NM_031889	ENAM	enamelin
chr16_-_24850163	0.257		ARHGAP17	Rho GTPase activating protein 17
chrX_-_30505804	0.254	NM_025159	CXorf21	chromosome X open reading frame 21
chr3_+_82117978	0.252
chr5_-_142795269	0.251	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_176671897	0.249	NM_001142935 NM_031300	MXD3	MAX dimerization protein 3
chr8_-_13018123	0.249	NM_001164271	DLC1	deleted in liver cancer 1
chr10_+_98730977	0.244	NM_015652	C10orf12	chromosome 10 open reading frame 12
chr6_-_159386007	0.244	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr2_-_207291364	0.244	NM_001093730	DYTN	dystrotelin
chr7_+_90177082	0.237		CDK14	cyclin-dependent kinase 14
chr10_+_129237602	0.236	NM_001030013	NPS	neuropeptide S
chr6_+_70633168	0.235	NM_001858	COL19A1	collagen, type XIX, alpha 1
chr21_-_33107813	0.231	NM_001162495 NM_001162496 NM_019596	C21orf62	chromosome 21 open reading frame 62
chr2_+_61243132	0.229	NM_001143959	C2orf74	chromosome 2 open reading frame 74
chr4_+_159351092	0.226		TMEM144	transmembrane protein 144
chr11_-_116168316	0.225	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr17_+_16061190	0.220	NM_004278	PIGL	phosphatidylinositol glycan anchor biosynthesis, class L
chr17_+_38247493	0.219		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr5_-_22889192	0.217		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr5_+_128328685	0.214		SLC27A6	solute carrier family 27 (fatty acid transporter), member 6
chr21_+_44941514	0.213	NM_198699	KRTAP10-12	keratin associated protein 10-12
chr18_+_70318001	0.212		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr6_-_28327980	0.211	NM_019110	ZKSCAN4	zinc finger with KRAB and SCAN domains 4
chr2_-_2313894	0.208	NM_015025	MYT1L	myelin transcription factor 1-like
chr15_-_74091817	0.207	NM_138573	NRG4	neuregulin 4
chr6_-_43054865	0.207		PEX6	peroxisomal biogenesis factor 6
chr5_+_180726874	0.206	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr1_-_109651140	0.206	NM_001010985	MYBPHL	myosin binding protein H-like
chr7_+_44612645	0.204	NM_001003941 NM_001165036 NM_002541	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr10_-_76488277	0.202	NM_001003892	DUPD1	dual specificity phosphatase and pro isomerase domain containing 1
chr6_+_32254108	0.200	NM_006913	RNF5	ring finger protein 5
chr18_-_59137948	0.193		BCL2	B-cell CLL/lymphoma 2
chr21_-_46849413	0.191	NM_006272	S100B	S100 calcium binding protein B
chr9_+_129951552	0.190	NM_005564	LCN2	lipocalin 2
chr12_+_63084317	0.190	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr1_-_246525502	0.190	NM_001004692	OR2T12	olfactory receptor, family 2, subfamily T, member 12
chr2_-_6924092	0.187		CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr18_-_29882555	0.187	NM_001198549	NOL4	nucleolar protein 4
chr5_-_179040580	0.186	NM_001164444	CBY3	chibby homolog 3 (Drosophila)
chr21_+_39745649	0.185	NM_007341	SH3BGR	SH3 domain binding glutamic acid-rich protein
chr10_+_35524835	0.185	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr3_+_153468518	0.184	NM_021038 NM_207292	MBNL1	muscleblind-like (Drosophila)
chr6_+_64414389	0.183	NM_015153	PHF3	PHD finger protein 3
chr9_+_92629525	0.182	NM_001174167	SYK	spleen tyrosine kinase
chr3_+_112743615	0.182	NM_005816 NM_198196	CD96	CD96 molecule
chr9_+_95886558	0.181	NM_152422	PTPDC1	protein tyrosine phosphatase domain containing 1
chr8_-_27997306	0.180	NM_001010906	C8orf80	chromosome 8 open reading frame 80
chr9_+_102987137	0.179	NM_017753	LPPR1	lipid phosphate phosphatase-related protein type 1
chr1_-_245237952	0.178		ZNF695	zinc finger protein 695
chr1_+_57093030	0.176	NM_000562	C8A	complement component 8, alpha polypeptide
chr6_-_166716353	0.173		BRP44L	brain protein 44-like
chr5_+_141326620	0.168	NM_183399	RNF14	ring finger protein 14
chr10_-_46039941	0.167	NM_001042357 NM_001042389	PTPN20B PTPN20A	protein tyrosine phosphatase, non-receptor type 20B protein tyrosine phosphatase, non-receptor type 20A
chr3_-_52544061	0.166	NM_022908	NT5DC2	5'-nucleotidase domain containing 2
chr22_+_29696662	0.158
chr11_+_56862395	0.157	NM_002559	P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3
chr12_-_9159789	0.155	NM_000014	A2M	alpha-2-macroglobulin
chr7_+_26644014	0.154	NM_001145531	C7orf71	chromosome 7 open reading frame 71
chr8_-_102034370	0.153	NM_001135699	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_+_58459131	0.153	NM_153331	KCTD6	potassium channel tetramerisation domain containing 6
chr21_-_44836811	0.150	NM_198688	KRTAP10-6	keratin associated protein 10-6
chr11_-_16387001	0.150	NM_001145811	SOX6	SRY (sex determining region Y)-box 6
chr17_+_17548888	0.148
chr19_+_44681425	0.147		DLL3	delta-like 3 (Drosophila)
chr9_-_124280025	0.146	NM_001004451	OR1J1	olfactory receptor, family 1, subfamily J, member 1
chr7_-_143560850	0.146	NM_001005287 NM_001001802	OR2A1 OR2A42	olfactory receptor, family 2, subfamily A, member 1 olfactory receptor, family 2, subfamily A, member 42
chr9_+_95886625	0.145		PTPDC1	protein tyrosine phosphatase domain containing 1
chrX_+_64625339	0.144	NM_001010888	ZC3H12B	zinc finger CCCH-type containing 12B
chrX_-_110541029	0.144	NM_000555	DCX	doublecortin
chr5_+_161208475	0.142	NM_001127646	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_+_32021899	0.141		CFB	complement factor B
chr20_-_62071584	0.138	NM_020713	ZNF512B	zinc finger protein 512B
chr10_-_50402148	0.137	NM_170753	PGBD3	piggyBac transposable element derived 3
chr12_-_119826433	0.136	NM_139015	SPPL3	signal peptide peptidase 3
chr14_+_19735334	0.135	NM_001005503	OR11G2	olfactory receptor, family 11, subfamily G, member 2
chr17_+_35471971	0.135	NM_001190919	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr12_-_21439637	0.135	NM_134431	SLCO1A2	solute carrier organic anion transporter family, member 1A2
chr6_-_11219932	0.132	NM_207582	ERVFRDE1	HERV-FRD provirus ancestral Env polyprotein
chr18_-_3001944	0.132	NM_014646	LPIN2	lipin 2
chr6_+_26705110	0.132	NM_013375	ABT1	activator of basal transcription 1
chr15_+_97990705	0.132	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr19_+_9222605	0.130	NM_001079935	OR7E24	olfactory receptor, family 7, subfamily E, member 24
chr5_-_169749215	0.130	NM_004137	KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr14_+_19598043	0.127	NM_001004717	OR4L1	olfactory receptor, family 4, subfamily L, member 1
chr12_-_119961143	0.127	NM_003733 NM_198213	OASL	2'-5'-oligoadenylate synthetase-like
chr1_-_9052207	0.127		SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr7_+_143646150	0.127	NM_001005287 NM_001001802	OR2A1 OR2A42	olfactory receptor, family 2, subfamily A, member 1 olfactory receptor, family 2, subfamily A, member 42
chr6_-_27988152	0.127	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr1_+_227506751	0.123	NM_006542	SPHAR	S-phase response (cyclin related)
chr4_-_68511738	0.123	NM_001114387 NM_182606	TMPRSS11A	transmembrane protease, serine 11A
chr17_+_63338500	0.121		BPTF	bromodomain PHD finger transcription factor
chr1_+_144374513	0.121		RNF115	ring finger protein 115
chr1_+_151498802	0.119	NM_000427	LOR	loricrin
chr4_+_95595419	0.118		PDLIM5	PDZ and LIM domain 5
chr11_+_62813947	0.116	NM_001039752	SLC22A10	solute carrier family 22, member 10
chr1_-_150564302	0.116	NM_002016	FLG	filaggrin

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.06	5.29e-12	GO:0007608	sensory perception of smell
4.66	2.45e-11	GO:0007606	sensory perception of chemical stimulus
3.07	1.98e-07	GO:0007600	sensory perception
2.22	2.65e-06	GO:0003008	system process
2.39	3.24e-06	GO:0050877	neurological system process
1.40	1.37e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.49	7.93e-04	GO:0005886	plasma membrane
6.54	1.46e-03	GO:0045095	keratin filament
1.47	1.51e-03	GO:0071944	cell periphery
1.36	5.95e-03	GO:0016021	integral to membrane
1.34	1.49e-02	GO:0031224	intrinsic to membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
5.30	3.08e-13	GO:0004984	olfactory receptor activity
2.74	5.13e-06	GO:0004930	G-protein coupled receptor activity
2.20	8.90e-05	GO:0004888	transmembrane receptor activity
1.98	1.39e-04	GO:0004872	receptor activity
1.74	3.00e-03	GO:0004871	signal transducer activity
1.74	3.00e-03	GO:0060089	molecular transducer activity