Motif ID: LMO2.p2

Z-value: 3.572


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)



Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_6923215 4.157 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr14_+_30413393 4.028 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr13_+_77170470 3.503 NM_001040153
SLAIN1
SLAIN motif family, member 1
chr1_+_90060131 3.469 LRRC8D
leucine rich repeat containing 8 family, member D
chr1_-_23729871 3.370 E2F2
E2F transcription factor 2
chr1_+_90059992 3.358 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chr5_+_168996852 3.065 DOCK2
dedicator of cytokinesis 2
chr11_+_817584 3.038 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr3_-_13436802 2.988 NM_024923
NUP210
nucleoporin 210kDa
chr5_+_168996816 2.968 NM_004946
DOCK2
dedicator of cytokinesis 2
chr17_-_18890963 2.911 NM_006613
GRAP
GRB2-related adaptor protein
chr16_-_87570716 2.901 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr17_+_73676219 2.881 NM_004710
SYNGR2
synaptogyrin 2
chr9_-_139084833 2.826 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr11_-_33847507 2.814 LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_92724181 2.811 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr1_+_12149637 2.781 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr6_+_11646472 2.709 NM_001100829
TMEM170B
transmembrane protein 170B
chr1_-_27113018 2.697 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr7_+_149696901 2.663 REPIN1
replication initiator 1
chr1_+_12149662 2.654 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr19_+_14405216 2.579 PKN1
protein kinase N1
chr1_-_1840564 2.561 NM_178545
TMEM52
transmembrane protein 52
chr16_-_30301357 2.553 SEPT1
septin 1
chr22_+_23153529 2.491 NM_000675
ADORA2A
adenosine A2a receptor
chr20_+_60744268 2.478 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr22_-_49317408 2.466 ODF3B
outer dense fiber of sperm tails 3B
chr1_+_89762984 2.442 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr9_-_96441409 2.428 FBP1
fructose-1,6-bisphosphatase 1
chr20_+_60744231 2.411 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr1_+_89763030 2.383 LRRC8B
leucine rich repeat containing 8 family, member B
chr1_-_3556420 2.367 NM_017818
WDR8
WD repeat domain 8
chr10_-_98470164 2.327 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr10_+_94598204 2.320 NM_019053
EXOC6
exocyst complex component 6
chr17_-_71747867 2.317 NM_052916
RNF157
ring finger protein 157
chr20_+_36867708 2.316 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr19_+_5082230 2.312 KDM4B
lysine (K)-specific demethylase 4B
chr2_+_222997529 2.310 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr17_-_44058612 2.300 NM_024017
HOXB9
homeobox B9
chr2_-_25328452 2.280 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr22_-_36212160 2.263 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr6_+_36206239 2.261 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr1_+_90059183 2.259 LRRC8D
leucine rich repeat containing 8 family, member D
chr12_-_61614930 2.247 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_6723801 2.232


chr5_+_156625629 2.201 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr5_-_176868483 2.187 DOK3
docking protein 3
chr10_-_103337872 2.144 POLL
polymerase (DNA directed), lambda
chr16_+_631902 2.129 FAM195A
family with sequence similarity 195, member A
chr10_+_92970302 2.105 NM_032373
PCGF5
polycomb group ring finger 5
chr2_+_222997456 2.097 SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_-_61615124 2.040 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_-_45444812 2.033 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr2_+_113648020 2.028 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr7_+_44754978 2.026 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr11_+_63864263 2.021 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr4_+_129951877 1.988 PHF17
PHD finger protein 17
chr1_-_23730298 1.978 NM_004091
E2F2
E2F transcription factor 2
chr14_-_22358752 1.959 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr3_-_13436725 1.934 NUP210
nucleoporin 210kDa
chr15_-_50375143 1.932 NM_018728
MYO5C
myosin VC
chr2_+_113648036 1.922 PSD4
pleckstrin and Sec7 domain containing 4
chr7_-_8268292 1.885 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr16_-_88613287 1.865 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr17_-_34015631 1.860 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr9_-_96441567 1.846 FBP1
fructose-1,6-bisphosphatase 1
chr11_-_124137260 1.846 NM_138961
ESAM
endothelial cell adhesion molecule
chr20_+_42463279 1.846 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr16_+_631828 1.828 NM_138418
FAM195A
family with sequence similarity 195, member A
chr6_-_3172775 1.818 NM_178012
TUBB2B
tubulin, beta 2B
chr9_+_70509925 1.797 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_+_18971506 1.788 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr20_-_23014828 1.784 NM_012072
CD93
CD93 molecule
chr22_-_22511173 1.768 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr15_-_46257745 1.765 NM_016132
MYEF2
myelin expression factor 2
chrX_-_118711144 1.740 SEPT6
septin 6
chr15_-_46257611 1.725 MYEF2
myelin expression factor 2
chrX_-_118711183 1.720 SEPT6
septin 6
chr17_-_16197433 1.720 NM_181716
CENPV
centromere protein V
chr4_+_39874921 1.719 NM_004310
RHOH
ras homolog gene family, member H
chr9_-_125070613 1.719 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr10_-_103337968 1.709 NM_001174084
NM_001174085
NM_013274
POLL


polymerase (DNA directed), lambda


chr22_+_35586950 1.669 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_+_95355415 1.667 NM_152487
TMEM56
transmembrane protein 56
chr5_-_94646033 1.665 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_190753833 1.664 NM_001042519
NM_032321
C2orf88

chromosome 2 open reading frame 88

chr9_+_139292094 1.664 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr2_+_171280944 1.662 SP5
Sp5 transcription factor
chr14_+_104337923 1.662 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr19_-_7607852 1.659


chr19_-_60587414 1.657 NM_001190764
LOC388564
hypothetical protein LOC388564
chr15_+_48261649 1.647 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr9_-_96441654 1.640 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr10_+_70257568 1.636 NM_001130162
STOX1
storkhead box 1
chr16_+_23754997 1.635 PRKCB
protein kinase C, beta
chr6_+_31647854 1.628 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_51690564 1.618 CHD9
chromodomain helicase DNA binding protein 9
chr10_+_92970487 1.616 PCGF5
polycomb group ring finger 5
chr10_+_70257299 1.602 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr19_+_60851207 1.592 CCDC106
coiled-coil domain containing 106
chrX_-_118711088 1.575 SEPT6
septin 6
chr3_+_39826032 1.570 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr7_-_8268206 1.562 NM_022307
ICA1
islet cell autoantigen 1, 69kDa
chr17_-_8809656 1.556 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr7_-_960534 1.556 ADAP1
ArfGAP with dual PH domains 1
chr5_+_95093267 1.551


chr16_-_1369613 1.549 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr2_+_170298487 1.545


chr7_+_50314801 1.544 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr16_-_55875953 1.540 PLLP
plasmolipin
chr11_-_33847834 1.537 LMO2
LIM domain only 2 (rhombotin-like 1)
chr20_+_42463419 1.534 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_-_44060729 1.528 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr19_-_1441403 1.526 NM_017573
PCSK4
proprotein convertase subtilisin/kexin type 4
chrX_-_118711350 1.526 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr17_-_4831388 1.525 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr22_-_20314274 1.511 NM_001017964
YDJC
YdjC homolog (bacterial)
chr9_-_125070675 1.506 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr20_+_42463350 1.506 HNF4A
hepatocyte nuclear factor 4, alpha
chr4_-_647424 1.503


chrX_+_152562013 1.500 DUSP9
dual specificity phosphatase 9
chr16_+_66022520 1.498 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr16_+_66022551 1.497 HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr15_+_86983038 1.497 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_131797455 1.497 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr1_+_42619014 1.493 NM_173642
RIMKLA
ribosomal modification protein rimK-like family member A
chr11_-_684842 1.487 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr7_+_1092968 1.485 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr19_-_1352474 1.465 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr7_+_149696792 1.460 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr20_+_42463387 1.457 HNF4A
hepatocyte nuclear factor 4, alpha
chr3_-_129690056 1.439 NM_001145661
GATA2
GATA binding protein 2
chr20_-_62081434 1.421 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr19_+_18145631 1.417 IFI30
interferon, gamma-inducible protein 30
chr19_+_7608010 1.416 STXBP2
syntaxin binding protein 2
chr19_-_6621078 1.410 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr14_+_71468902 1.395 RGS6
regulator of G-protein signaling 6
chr19_+_7608020 1.386 STXBP2
syntaxin binding protein 2
chr2_+_176761552 1.384 NM_024501
HOXD1
homeobox D1
chr1_+_109827975 1.382 NM_153340
ATXN7L2
ataxin 7-like 2
chr19_-_14177980 1.378 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr16_-_2330594 1.377 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_+_6723705 1.371 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr16_-_55876099 1.366 PLLP
plasmolipin
chr2_+_219453487 1.364 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr19_+_18145619 1.362 IFI30
interferon, gamma-inducible protein 30
chr19_-_53914768 1.359 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr19_+_7607976 1.358 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr20_+_48032918 1.352 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr19_-_1441340 1.351 PCSK4
proprotein convertase subtilisin/kexin type 4
chr19_+_10392128 1.338 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr15_+_81567327 1.334 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr16_-_2330738 1.333 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_-_11550765 1.333 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr8_+_143805595 1.333 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr22_-_20314366 1.315 YDJC
YdjC homolog (bacterial)
chr9_+_115265827 1.312 NM_017790
RGS3
regulator of G-protein signaling 3
chr6_+_31648071 1.311 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr17_+_40655060 1.299 NM_005892
FMNL1
formin-like 1
chr8_+_11599119 1.298 NM_002052
GATA4
GATA binding protein 4
chr20_-_62081752 1.287 SAMD10
sterile alpha motif domain containing 10
chr15_-_99847109 1.284 PCSK6
proprotein convertase subtilisin/kexin type 6
chr16_-_55876075 1.282 NM_015993
PLLP
plasmolipin
chr4_-_2390050 1.279 NM_001172656
NM_001172657
NM_001172658
NM_020972
ZFYVE28



zinc finger, FYVE domain containing 28



chr10_+_82158186 1.277 NM_032333
C10orf58
chromosome 10 open reading frame 58
chr2_+_170298700 1.276 KLHL23
kelch-like 23 (Drosophila)
chr15_+_62230962 1.273 NM_024798
SNX22
sorting nexin 22
chr17_-_36594652 1.269 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr5_+_75734759 1.268 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr1_-_218168404 1.267


chr9_+_139437624 1.267 NM_006647
NOXA1
NADPH oxidase activator 1
chr22_-_49311722 1.266 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr16_-_1816529 1.264 HAGH
hydroxyacylglutathione hydrolase
chr1_-_111548440 1.255 DENND2D
DENN/MADD domain containing 2D
chr17_-_70480385 1.252 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr6_+_44295219 1.251 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr11_+_64635870 1.250 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chr8_+_104452877 1.245 CTHRC1
collagen triple helix repeat containing 1
chr4_+_6962438 1.245 TBC1D14
TBC1 domain family, member 14
chr4_-_42353640 1.245 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr18_-_6404900 1.240 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr17_+_58908152 1.238 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr22_+_20068039 1.237 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_-_1701313 1.228 NM_001198994
NADK
NAD kinase
chr17_-_70480345 1.226


chr17_-_3814334 1.221 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr14_-_105392671 1.213


chr16_+_56616782 1.213 NM_002428
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr20_+_62158882 1.199 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr5_+_126140949 1.198 LMNB1
lamin B1
chr22_+_16973399 1.189 NM_001193414
NM_018943
TUBA8

tubulin, alpha 8

chr1_-_24112345 1.185 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr7_-_3049872 1.184 NM_032415
CARD11
caspase recruitment domain family, member 11
chr16_+_23754860 1.178 PRKCB
protein kinase C, beta
chr1_-_92124064 1.172 TGFBR3
transforming growth factor, beta receptor III
chrX_+_115481774 1.171 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_+_1062137 1.171 LOC254099
hypothetical protein LOC254099
chr5_-_138753443 1.170 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr3_+_16901455 1.168 NM_001144382
PLCL2
phospholipase C-like 2
chr19_-_11550576 1.168 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 8.07e-03 GO:0071310 cellular response to organic substance
1.25 1.27e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 1.13e-05 GO:0005737 cytoplasm
1.06 6.96e-04 GO:0044424 intracellular part
1.05 4.82e-03 GO:0005622 intracellular
1.09 4.40e-02 GO:0044444 cytoplasmic part

Nothing significant found in function category.