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• Mean activities

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• Activity deltas table
• Regulatory interactions
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Motif ID: MAFB.p2

Z-value: 3.251

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_-_109291575	4.800		KLF4	Kruppel-like factor 4 (gut)
chr4_-_141293572	4.447		MAML3	mastermind-like 3 (Drosophila)
chr15_-_37999519	4.198
chr6_+_45498262	4.160		RUNX2	runt-related transcription factor 2
chr6_+_45498354	3.770		RUNX2	runt-related transcription factor 2
chr2_-_161058120	3.643		RBMS1	RNA binding motif, single stranded interacting protein 1
chr4_-_140696740	3.568	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr15_-_37999717	3.276		GPR176	G protein-coupled receptor 176
chr7_-_27149750	3.050	NM_019102	HOXA5	homeobox A5
chr1_+_66772393	3.022	NM_032291	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr18_-_21185968	3.007		ZNF521	zinc finger protein 521
chr4_-_141294682	2.922	NM_018717	MAML3	mastermind-like 3 (Drosophila)
chr5_+_60663842	2.881	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr8_+_37672427	2.847	NM_025069	ZNF703	zinc finger protein 703
chr7_-_127458231	2.809	NM_022143	LRRC4	leucine rich repeat containing 4
chr3_-_64186151	2.778	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr13_-_76358370	2.769		KCTD12	potassium channel tetramerisation domain containing 12
chr9_-_128924782	2.751		ANGPTL2	angiopoietin-like 2
chr9_-_128924819	2.748	NM_012098	ANGPTL2	angiopoietin-like 2
chr9_-_128924706	2.742		ANGPTL2	angiopoietin-like 2
chr16_+_81218142	2.709		CDH13	cadherin 13, H-cadherin (heart)
chr18_-_21186107	2.668	NM_015461	ZNF521	zinc finger protein 521
chr16_+_81218074	2.647	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr2_-_227371698	2.559	NM_005544	IRS1	insulin receptor substrate 1
chr15_-_46724360	2.499		FBN1	fibrillin 1
chr2_-_192767494	2.493		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_+_26239755	2.459	NM_005086	SSPN	sarcospan (Kras oncogene-associated gene)
chr9_-_25668230	2.366		TUSC1	tumor suppressor candidate 1
chr1_+_64012154	2.364	NM_001083592 NM_005012	ROR1	receptor tyrosine kinase-like orphan receptor 1
chr9_-_109291866	2.331	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr5_+_92946348	2.323		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr3_+_112273352	2.308		PVRL3	poliovirus receptor-related 3
chr11_-_35503720	2.280	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr20_+_19903778	2.256		RIN2	Ras and Rab interactor 2
chr8_+_32525269	2.252	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr7_+_33911636	2.248	NM_133468	BMPER	BMP binding endothelial regulator
chr6_-_132314004	2.203	NM_001901	CTGF	connective tissue growth factor
chr8_+_60194328	2.187
chr7_-_27190882	2.169		HOXA11	homeobox A11
chr8_+_106400322	2.126	NM_012082	ZFPM2	zinc finger protein, multitype 2
chr18_-_24010944	2.087		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_146813343	2.075	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr5_+_66160359	2.048	NM_015183	MAST4	microtubule associated serine/threonine kinase family member 4
chr12_-_26166485	2.042		BHLHE41	basic helix-loop-helix family, member e41
chr9_-_34448477	2.021	NM_001184940 NM_001184941 NM_001184942 NM_001184943 NM_001184944 NM_001184945 NM_147202	C9orf25	chromosome 9 open reading frame 25
chr2_+_109112428	2.018	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr3_-_188945921	1.995		BCL6	B-cell CLL/lymphoma 6
chr9_-_16717887	1.975		BNC2	basonuclin 2
chr15_+_72006015	1.913		LOXL1	lysyl oxidase-like 1
chr1_+_199884152	1.912		NAV1	neuron navigator 1
chr10_+_52504239	1.910	NM_006258	PRKG1	protein kinase, cGMP-dependent, type I
chr5_+_129268352	1.897	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr6_-_75972286	1.887	NM_004370 NM_080645	COL12A1	collagen, type XII, alpha 1
chr2_-_161058550	1.877	NM_002897 NM_016836	RBMS1	RNA binding motif, single stranded interacting protein 1
chr3_+_106568243	1.877		ALCAM	activated leukocyte cell adhesion molecule
chr7_+_27190688	1.864
chr5_-_72779585	1.853		FOXD1	forkhead box D1
chr2_-_68400516	1.850	NM_001111101 NM_015463	CNRIP1	cannabinoid receptor interacting protein 1
chrX_-_34585287	1.843	NM_031442	TMEM47	transmembrane protein 47
chr19_-_45888259	1.835	NM_004756	NUMBL	numb homolog (Drosophila)-like
chr10_+_59942874	1.831	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr5_+_42459568	1.817	NM_000163	GHR	growth hormone receptor
chr11_-_88864061	1.817	NM_001143836 NM_016931	NOX4	NADPH oxidase 4
chr20_-_22978141	1.815	NM_000361	THBD	thrombomodulin
chr14_+_85066265	1.812		FLRT2	fibronectin leucine rich transmembrane protein 2
chr12_+_62524778	1.792	NM_020762	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1
chr1_+_182622987	1.792		C1orf21	chromosome 1 open reading frame 21
chr1_-_72521079	1.790
chr16_+_85158357	1.785	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr15_+_41597097	1.772	NM_002373	MAP1A	microtubule-associated protein 1A
chr3_-_87122936	1.769	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr4_-_111763655	1.762	NM_000325	PITX2	paired-like homeodomain 2
chr8_-_108579270	1.758	NM_001146	ANGPT1	angiopoietin 1
chr4_-_111763356	1.756		PITX2	paired-like homeodomain 2
chr3_-_87122958	1.752		VGLL3	vestigial like 3 (Drosophila)
chr15_-_53667800	1.736		PYGO1	pygopus homolog 1 (Drosophila)
chr13_-_25523164	1.731	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr11_-_10272256	1.705	NM_030962	SBF2	SET binding factor 2
chr14_+_85066207	1.704	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr11_+_19691397	1.688	NM_145117 NM_182964	NAV2	neuron navigator 2
chr14_-_26136799	1.687	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr17_+_1905104	1.685	NM_006497	HIC1	hypermethylated in cancer 1
chr14_+_32478209	1.684	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr11_+_94141151	1.678	NM_130847	AMOTL1	angiomotin like 1
chr16_+_1524162	1.661	NM_024600	TMEM204	transmembrane protein 204
chr1_-_158091296	1.656		C1orf204	chromosome 1 open reading frame 204
chr3_-_16530132	1.646	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr12_-_74711474	1.645		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr4_-_122063118	1.641	NM_018699	PRDM5	PR domain containing 5
chr6_-_78229838	1.635	NM_000863	HTR1B	5-hydroxytryptamine (serotonin) receptor 1B
chr6_-_91063301	1.602	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr13_+_100902942	1.600	NM_004791	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr9_-_109291130	1.592		KLF4	Kruppel-like factor 4 (gut)
chr8_-_13178327	1.589
chr10_-_60792666	1.584	NM_001143773	FAM13C	family with sequence similarity 13, member C
chr2_-_156897286	1.579	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr3_-_189354510	1.577		LOC339929	hypothetical LOC339929
chr17_+_56832492	1.573		TBX2	T-box 2
chr5_-_146869811	1.568	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr7_-_78920806	1.564	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_79835970	1.561	NM_002072	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide
chr19_-_1518875	1.555	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr19_-_19793512	1.548	NM_001099269 NM_001145404	ZNF506	zinc finger protein 506
chrX_+_66683075	1.542		AR	androgen receptor
chr10_-_60792225	1.528	NM_001001971 NM_001166698 NM_198215	FAM13C	family with sequence similarity 13, member C
chr17_+_56832255	1.526		TBX2	T-box 2
chr12_+_26239535	1.526	NM_001135823	SSPN	sarcospan (Kras oncogene-associated gene)
chr2_+_238200922	1.525	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr2_+_23461802	1.523	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chrX_+_51503219	1.516	NM_018094	GSPT2	G1 to S phase transition 2
chr5_-_146869613	1.511		DPYSL3	dihydropyrimidinase-like 3
chr10_+_72102563	1.510	NM_080722 NM_139155	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr10_+_111755715	1.503	NM_019903	ADD3	adducin 3 (gamma)
chr11_+_110916629	1.495		LAYN	layilin
chr4_+_108965167	1.490	NM_001136258	SGMS2	sphingomyelin synthase 2
chr1_-_72520735	1.490	NM_173808	NEGR1	neuronal growth regulator 1
chr2_-_160972606	1.481		RBMS1	RNA binding motif, single stranded interacting protein 1
chr5_-_58370693	1.480	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr11_+_101290930	1.468	NM_020802	KIAA1377	KIAA1377
chr5_+_40715799	1.467		PTGER4	prostaglandin E receptor 4 (subtype EP4)
chr2_-_236741352	1.465	NM_001485	GBX2	gastrulation brain homeobox 2
chr8_-_89408832	1.460	NM_005941	MMP16	matrix metallopeptidase 16 (membrane-inserted)
chr12_+_56406296	1.458		LOC100130776	hypothetical LOC100130776
chr3_+_112273464	1.456	NM_015480	PVRL3	poliovirus receptor-related 3
chr3_-_185025989	1.451	NM_024871	MAP6D1	MAP6 domain containing 1
chr5_+_40715778	1.448	NM_000958	PTGER4	prostaglandin E receptor 4 (subtype EP4)
chr7_-_41709191	1.417	NM_002192	INHBA	inhibin, beta A
chr15_-_50608296	1.406	NM_000259 NM_001142495	MYO5A	myosin VA (heavy chain 12, myoxin)
chr7_+_115926679	1.396	NM_001233 NM_198212	CAV2	caveolin 2
chr7_+_116099648	1.395	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr9_-_83493415	1.387	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr17_+_56831951	1.387	NM_005994	TBX2	T-box 2
chr9_-_112381593	1.380	NM_153366	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr3_-_114947681	1.379	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_+_131285747	1.368	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr1_-_203447314	1.364	NM_015375 NM_199462	DSTYK	dual serine/threonine and tyrosine protein kinase
chr12_-_29827952	1.353	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr2_+_85213884	1.350	NM_031283	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
chr7_-_19123765	1.344		TWIST1	twist homolog 1 (Drosophila)
chrX_+_149282097	1.338	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr15_-_23659329	1.338	NM_024490	ATP10A	ATPase, class V, type 10A
chr1_-_143643324	1.332	NM_001002811	PDE4DIP	phosphodiesterase 4D interacting protein
chr1_-_85816520	1.323	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr3_+_49002285	1.319	NM_177938 NM_177939	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr7_-_19123787	1.313	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr12_+_95112385	1.310		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr19_+_43572679	1.307	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr3_+_49002774	1.305		P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr12_-_106011715	1.301	NM_004075	CRY1	cryptochrome 1 (photolyase-like)
chr12_+_52665196	1.297	NM_017409	HOXC10	homeobox C10
chr20_+_52525538	1.288	NM_018431	DOK5	docking protein 5
chr3_+_189354167	1.279	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr5_-_107034484	1.279	NM_001962	EFNA5	ephrin-A5
chrX_-_83329562	1.278	NM_014496	RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr11_-_85108030	1.278	NM_001162952 NM_206930	SYTL2	synaptotagmin-like 2
chr2_+_56265260	1.278
chr20_+_6696744	1.277	NM_001200	BMP2	bone morphogenetic protein 2
chr9_-_109290107	1.259		KLF4	Kruppel-like factor 4 (gut)
chr20_-_55718351	1.259	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr13_-_107317460	1.255	NM_001080396	FAM155A	family with sequence similarity 155, member A
chr2_-_210744158	1.252	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr18_+_54681657	1.247		ZNF532	zinc finger protein 532
chr11_-_129803515	1.247		ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr15_-_81037554	1.244	NM_001079533 NM_001079534 NM_001079535	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr14_-_102593384	1.243	NM_006035	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr14_+_37748345	1.233		SSTR1	somatostatin receptor 1
chr5_-_112658200	1.232		MCC	mutated in colorectal cancers
chr13_-_43259032	1.229	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr9_+_129893948	1.227	NM_001006642	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr17_+_56888588	1.221	NM_018488	TBX4	T-box 4
chr8_-_13178399	1.217		DLC1	deleted in liver cancer 1
chr8_+_104222052	1.217	NM_001024372 NM_024812	BAALC	brain and acute leukemia, cytoplasmic
chr15_+_97009194	1.204		IGF1R	insulin-like growth factor 1 receptor
chr4_-_138673014	1.204		PCDH18	protocadherin 18
chr7_+_28415495	1.188		LOC401317	hypothetical LOC401317
chr15_-_80125514	1.188		MEX3B	mex-3 homolog B (C. elegans)
chr19_-_36531958	1.184	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr2_+_12774264	1.181	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr8_-_11096257	1.178	NM_173683	XKR6	XK, Kell blood group complex subunit-related family, member 6
chr5_+_17270474	1.177	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr19_-_50977592	1.175	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr5_-_37875538	1.174	NM_000514	GDNF	glial cell derived neurotrophic factor
chr12_-_93568336	1.168	NM_020698	TMCC3	transmembrane and coiled-coil domain family 3
chr2_-_183610992	1.166		NCKAP1	NCK-associated protein 1
chr16_-_62573	1.165	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr15_-_32875040	1.164	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr10_-_105604942	1.164	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr1_+_64709063	1.162	NM_020925	CACHD1	cache domain containing 1
chr6_+_71434192	1.162	NM_001044305 NM_021940	SMAP1	small ArfGAP 1
chr22_-_34754343	1.160	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_78920846	1.153		LOC100505881	hypothetical LOC100505881
chr12_-_94708477	1.141		NTN4	netrin 4
chr15_+_45796802	1.141		SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_+_52026058	1.140	NM_005450	NOG	noggin
chr6_+_1556543	1.136		FOXC1	forkhead box C1
chr13_+_113546841	1.134	NM_000820	GAS6	growth arrest-specific 6
chr1_-_33669190	1.133		PHC2	polyhomeotic homolog 2 (Drosophila)
chr5_+_17270781	1.131		BASP1	brain abundant, membrane attached signal protein 1
chr2_+_36436316	1.129		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr10_-_106088151	1.129		ITPRIP	inositol 1,4,5-triphosphate receptor interacting protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	5.96e-19	GO:0050794	regulation of cellular process
1.17	8.51e-17	GO:0050789	regulation of biological process
1.38	1.60e-15	GO:0048523	negative regulation of cellular process
1.15	4.40e-15	GO:0065007	biological regulation
1.26	2.49e-14	GO:0032502	developmental process
1.43	3.25e-13	GO:0009653	anatomical structure morphogenesis
1.67	7.90e-13	GO:0007167	enzyme linked receptor protein signaling pathway
1.25	8.62e-13	GO:0023052	signaling
1.33	8.65e-13	GO:0048519	negative regulation of biological process
1.26	1.03e-12	GO:0007275	multicellular organismal development
1.09	1.35e-12	GO:0009987	cellular process
1.27	3.32e-12	GO:0048856	anatomical structure development
1.31	4.31e-12	GO:0048522	positive regulation of cellular process
1.28	8.97e-12	GO:0048731	system development
1.72	1.94e-11	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.25	2.16e-11	GO:0007165	signal transduction
1.75	2.65e-11	GO:0072358	cardiovascular system development
1.75	2.65e-11	GO:0072359	circulatory system development
1.96	2.94e-11	GO:0001944	vasculature development
1.33	4.89e-11	GO:0048869	cellular developmental process
1.33	7.28e-11	GO:0030154	cell differentiation
1.28	1.25e-10	GO:0048518	positive regulation of biological process
1.49	1.20e-09	GO:0022008	neurogenesis
1.39	5.39e-09	GO:0051239	regulation of multicellular organismal process
1.36	1.12e-08	GO:0007399	nervous system development
1.48	1.47e-08	GO:0048699	generation of neurons
1.32	1.95e-08	GO:0007166	cell surface receptor linked signaling pathway
1.45	4.44e-08	GO:0048468	cell development
1.86	7.07e-08	GO:0001568	blood vessel development
1.19	1.02e-07	GO:0051716	cellular response to stimulus
1.32	1.26e-07	GO:0023051	regulation of signaling
1.21	1.38e-07	GO:0080090	regulation of primary metabolic process
1.21	2.12e-07	GO:0060255	regulation of macromolecule metabolic process
1.41	2.64e-07	GO:0042981	regulation of apoptosis
1.40	2.76e-07	GO:0043067	regulation of programmed cell death
1.20	5.28e-07	GO:0031323	regulation of cellular metabolic process
1.39	7.01e-07	GO:0010941	regulation of cell death
1.58	1.10e-06	GO:0000904	cell morphogenesis involved in differentiation
1.49	1.15e-06	GO:0030182	neuron differentiation
1.15	1.16e-06	GO:0032501	multicellular organismal process
1.89	1.23e-06	GO:0048514	blood vessel morphogenesis
1.49	1.30e-06	GO:0045595	regulation of cell differentiation
1.28	1.80e-06	GO:0006464	protein modification process
1.62	1.92e-06	GO:0007409	axonogenesis
1.17	2.95e-06	GO:0044260	cellular macromolecule metabolic process
1.32	3.52e-06	GO:0009966	regulation of signal transduction
1.72	4.35e-06	GO:0022603	regulation of anatomical structure morphogenesis
1.41	4.43e-06	GO:0050793	regulation of developmental process
1.52	4.62e-06	GO:0048666	neuron development
1.49	4.78e-06	GO:0030030	cell projection organization
1.18	4.97e-06	GO:0019222	regulation of metabolic process
1.56	6.02e-06	GO:0031175	neuron projection development
1.59	7.21e-06	GO:0048812	neuron projection morphogenesis
1.37	7.30e-06	GO:0010646	regulation of cell communication
1.59	7.37e-06	GO:0048667	cell morphogenesis involved in neuron differentiation
1.49	7.72e-06	GO:0032989	cellular component morphogenesis
1.38	8.58e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.49	1.28e-05	GO:0000902	cell morphogenesis
1.53	2.85e-05	GO:0048858	cell projection morphogenesis
1.35	2.95e-05	GO:0051246	regulation of protein metabolic process
1.22	2.95e-05	GO:0044267	cellular protein metabolic process
1.42	3.56e-05	GO:2000026	regulation of multicellular organismal development
1.56	4.25e-05	GO:0010648	negative regulation of cell communication
1.33	5.17e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.51	5.53e-05	GO:0032990	cell part morphogenesis
1.25	5.98e-05	GO:0043412	macromolecule modification
1.31	1.06e-04	GO:0009893	positive regulation of metabolic process
1.62	1.13e-04	GO:0007411	axon guidance
1.35	1.16e-04	GO:0032268	regulation of cellular protein metabolic process
1.56	1.23e-04	GO:0009968	negative regulation of signal transduction
1.54	1.26e-04	GO:0023057	negative regulation of signaling
1.39	1.38e-04	GO:0051128	regulation of cellular component organization
1.43	1.68e-04	GO:0042325	regulation of phosphorylation
1.29	1.92e-04	GO:0035556	intracellular signal transduction
1.88	1.98e-04	GO:0001525	angiogenesis
1.42	2.14e-04	GO:0009790	embryo development
1.40	2.22e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.51	2.23e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.63	2.31e-04	GO:0032870	cellular response to hormone stimulus
1.41	2.44e-04	GO:0019220	regulation of phosphate metabolic process
1.41	2.44e-04	GO:0051174	regulation of phosphorus metabolic process
1.74	2.69e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.62	2.82e-04	GO:0060284	regulation of cell development
1.37	2.85e-04	GO:0040011	locomotion
1.21	2.89e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.31	3.63e-04	GO:0031325	positive regulation of cellular metabolic process
1.19	4.85e-04	GO:0009889	regulation of biosynthetic process
1.33	5.53e-04	GO:0006793	phosphorus metabolic process
1.33	5.53e-04	GO:0006796	phosphate metabolic process
1.20	6.98e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.40	7.49e-04	GO:0010628	positive regulation of gene expression
1.47	7.83e-04	GO:0043068	positive regulation of programmed cell death
1.19	8.20e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.46	8.48e-04	GO:0010942	positive regulation of cell death
1.47	8.71e-04	GO:0043065	positive regulation of apoptosis
1.58	8.75e-04	GO:0071495	cellular response to endogenous stimulus
1.43	9.65e-04	GO:0042060	wound healing
1.19	9.72e-04	GO:0031326	regulation of cellular biosynthetic process
1.42	1.03e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.90	1.21e-03	GO:0008286	insulin receptor signaling pathway
1.41	1.24e-03	GO:0001932	regulation of protein phosphorylation
1.32	1.25e-03	GO:0007154	cell communication
1.19	1.27e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58	1.33e-03	GO:0001501	skeletal system development
1.13	1.37e-03	GO:0043170	macromolecule metabolic process
1.37	1.53e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	1.80e-03	GO:0032879	regulation of localization
1.32	1.95e-03	GO:0042127	regulation of cell proliferation
1.50	2.11e-03	GO:0016477	cell migration
1.39	2.40e-03	GO:0051254	positive regulation of RNA metabolic process
1.35	2.86e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.37	2.92e-03	GO:0006915	apoptosis
1.34	2.95e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.35	3.31e-03	GO:0031399	regulation of protein modification process
1.34	3.37e-03	GO:0009891	positive regulation of biosynthetic process
1.48	3.54e-03	GO:0008285	negative regulation of cell proliferation
1.36	3.79e-03	GO:0012501	programmed cell death
1.44	4.64e-03	GO:0048585	negative regulation of response to stimulus
1.65	5.92e-03	GO:0071375	cellular response to peptide hormone stimulus
1.62	5.97e-03	GO:0000165	MAPKKK cascade
1.73	6.12e-03	GO:0032869	cellular response to insulin stimulus
1.32	6.40e-03	GO:0008219	cell death
1.32	6.44e-03	GO:0016265	death
1.21	7.69e-03	GO:0048583	regulation of response to stimulus
1.18	7.82e-03	GO:0010468	regulation of gene expression
1.57	7.95e-03	GO:0051270	regulation of cellular component movement
1.35	8.35e-03	GO:0006468	protein phosphorylation
1.49	8.82e-03	GO:0007264	small GTPase mediated signal transduction
1.16	1.02e-02	GO:0019538	protein metabolic process
1.62	1.10e-02	GO:0030168	platelet activation
1.34	1.22e-02	GO:0007267	cell-cell signaling
1.56	1.27e-02	GO:0040012	regulation of locomotion
1.44	1.43e-02	GO:0048870	cell motility
1.44	1.43e-02	GO:0051674	localization of cell
1.43	1.57e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.56	1.74e-02	GO:0061061	muscle structure development
1.15	1.84e-02	GO:0016043	cellular component organization
1.57	2.05e-02	GO:0030334	regulation of cell migration
1.49	2.20e-02	GO:0006917	induction of apoptosis
1.18	2.31e-02	GO:0051252	regulation of RNA metabolic process
1.82	2.39e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.87	2.41e-02	GO:0035023	regulation of Rho protein signal transduction
1.48	2.56e-02	GO:0012502	induction of programmed cell death
2.85	2.57e-02	GO:0030199	collagen fibril organization
1.30	2.57e-02	GO:0031324	negative regulation of cellular metabolic process
1.38	2.75e-02	GO:0006928	cellular component movement
1.39	2.99e-02	GO:0070727	cellular macromolecule localization
1.34	3.00e-02	GO:0009890	negative regulation of biosynthetic process
1.20	3.04e-02	GO:0048513	organ development
1.29	3.11e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.16	3.12e-02	GO:0071842	cellular component organization at cellular level
1.81	3.12e-02	GO:0022604	regulation of cell morphogenesis
1.39	3.32e-02	GO:0034613	cellular protein localization
1.55	3.53e-02	GO:2000145	regulation of cell motility
1.40	3.64e-02	GO:0043549	regulation of kinase activity
1.34	3.98e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.28	4.06e-02	GO:0009892	negative regulation of metabolic process
1.18	4.82e-02	GO:0006355	regulation of transcription, DNA-dependent
1.29	4.88e-02	GO:0009888	tissue development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.07	7.96e-08	GO:0005622	intracellular
1.07	2.70e-07	GO:0044424	intracellular part
1.43	7.33e-05	GO:0030054	cell junction
1.52	8.41e-05	GO:0043005	neuron projection
1.08	1.23e-04	GO:0005737	cytoplasm
1.50	2.48e-04	GO:0045202	synapse
1.16	5.80e-04	GO:0043234	protein complex
1.76	5.97e-04	GO:0070161	anchoring junction
1.79	7.06e-04	GO:0005912	adherens junction
1.19	7.34e-04	GO:0044459	plasma membrane part
1.61	1.21e-02	GO:0030425	dendrite
2.06	1.38e-02	GO:0030427	site of polarized growth
1.28	1.46e-02	GO:0042995	cell projection
2.05	2.02e-02	GO:0030426	growth cone
1.60	2.71e-02	GO:0031252	cell leading edge
1.19	3.01e-02	GO:0005856	cytoskeleton
1.38	3.80e-02	GO:0044463	cell projection part
1.09	3.90e-02	GO:0005634	nucleus
1.16	4.91e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	6.91e-21	GO:0005515	protein binding
1.09	3.60e-14	GO:0005488	binding
1.49	1.22e-07	GO:0043565	sequence-specific DNA binding
1.38	1.41e-06	GO:0001071	nucleic acid binding transcription factor activity
1.38	1.41e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.36	4.70e-06	GO:0030528	transcription regulator activity
1.36	4.42e-04	GO:0019899	enzyme binding
1.93	8.27e-04	GO:0051020	GTPase binding
1.77	1.30e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.58	1.80e-03	GO:0032403	protein complex binding
2.07	2.51e-03	GO:0019199	transmembrane receptor protein kinase activity
1.99	3.29e-03	GO:0017016	Ras GTPase binding
1.18	3.93e-03	GO:0000166	nucleotide binding
1.93	3.96e-03	GO:0031267	small GTPase binding
1.38	7.71e-03	GO:0008092	cytoskeletal protein binding
1.94	9.16e-03	GO:0005088	Ras guanyl-nucleotide exchange factor activity
2.05	1.15e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.40	1.21e-02	GO:0030695	GTPase regulator activity
1.38	2.07e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.39	2.49e-02	GO:0019904	protein domain specific binding