Motif ID: MAZ.p2

Z-value: 2.954


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)



Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_26895108 4.774 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr5_+_139008209 4.491 NM_016463
CXXC5
CXXC finger protein 5
chr2_-_25328452 4.149 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_+_61841662 3.883 SLC2A4RG
SLC2A4 regulator
chrX_+_9392980 3.789 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr8_+_144706699 3.741 NM_001166237
GSDMD
gasdermin D
chr20_-_34635091 3.427


chr20_+_61841553 3.177 NM_020062
SLC2A4RG
SLC2A4 regulator
chr19_-_55524445 3.032 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr9_+_70509925 2.960 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_-_39652449 2.902 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr19_+_659766 2.764 NM_001040134
NM_002579
PALM

paralemmin

chr14_-_21064182 2.750 SALL2
sal-like 2 (Drosophila)
chr1_-_32574185 2.709 NM_023009
MARCKSL1
MARCKS-like 1
chrX_+_138060 2.579 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr15_+_38550451 2.578 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr16_+_49139694 2.494 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr12_+_56291484 2.467 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr5_+_139008667 2.462 CXXC5
CXXC finger protein 5
chr20_+_34635362 2.461 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr2_-_174537354 2.380 SP3
Sp3 transcription factor
chr17_-_53764867 2.367


chr16_+_29725311 2.332 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr22_-_17545872 2.291 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr5_+_139008139 2.287 CXXC5
CXXC finger protein 5
chr4_-_6253152 2.258 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr6_+_37245860 2.229 NM_002648
PIM1
pim-1 oncogene
chr17_-_39652391 2.194 UBTF
upstream binding transcription factor, RNA polymerase I
chr12_+_93066370 2.178 NM_005761
PLXNC1
plexin C1
chr5_-_134397740 2.170 NM_002653
PITX1
paired-like homeodomain 1
chr20_-_30534848 2.141 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr19_+_14405216 2.135 PKN1
protein kinase N1
chr20_-_61755145 2.129 NM_015894
STMN3
stathmin-like 3
chr5_+_139008091 2.036 CXXC5
CXXC finger protein 5
chr22_+_38183480 1.991 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_3679168 1.987 NM_001163724
LOC388588
hypothetical protein LOC388588
chr17_-_39632845 1.946 ATXN7L3
ataxin 7-like 3
chr20_-_62071584 1.934 NM_020713
ZNF512B
zinc finger protein 512B
chr7_+_137795719 1.917 TRIM24
tripartite motif containing 24
chr6_+_7052798 1.881 NM_001168344
RREB1
ras responsive element binding protein 1
chr7_+_68702516 1.870 AUTS2
autism susceptibility candidate 2
chr2_-_74634569 1.862 NM_032603
LOXL3
lysyl oxidase-like 3
chr2_+_42128521 1.856 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr16_+_29724926 1.855 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_-_135021502 1.849 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr10_+_31648103 1.781 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr2_+_232281470 1.757 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr6_+_169866714 1.753 LOC729088
hypothetical LOC729088
chr7_-_158073121 1.734 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr14_+_102659464 1.734 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr2_+_232281491 1.714 PTMA
prothymosin, alpha
chr1_-_233879617 1.708 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr16_-_30042030 1.694 MAPK3
mitogen-activated protein kinase 3
chr20_-_62181588 1.693 NM_001039467
RGS19
regulator of G-protein signaling 19
chr6_+_7052985 1.690 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr2_-_61551403 1.680 USP34
ubiquitin specific peptidase 34
chr3_+_20056527 1.666 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr2_+_220117009 1.661 TMEM198
transmembrane protein 198
chr16_-_960796 1.656 LMF1
lipase maturation factor 1
chr20_+_44083667 1.655 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_+_74635019 1.645 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr18_-_28606839 1.644 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr20_-_22512893 1.642 FOXA2
forkhead box A2
chr17_+_35751796 1.634 NM_001024809
RARA
retinoic acid receptor, alpha
chr4_+_57469122 1.634 REST
RE1-silencing transcription factor
chr12_+_56202874 1.626 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr19_+_10574055 1.624 NM_001145056
SLC44A2
solute carrier family 44, member 2
chr10_+_76256305 1.622 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr11_+_47958835 1.615 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr16_-_371823 1.611 NM_021259
TMEM8A
transmembrane protein 8A
chr12_-_61614930 1.595 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_14062230 1.595 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr9_-_125732005 1.590 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr17_-_60986905 1.589 AXIN2
axin 2
chr20_-_62181231 1.584 NM_005873
RGS19
regulator of G-protein signaling 19
chr10_+_94439658 1.558 NM_002729
HHEX
hematopoietically expressed homeobox
chr6_-_32265489 1.552 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr19_+_3310138 1.549 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr1_+_153241665 1.544 NM_015872
ZBTB7B
zinc finger and BTB domain containing 7B
chr9_-_139564656 1.540 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr2_+_220116986 1.540 NM_001005209
TMEM198
transmembrane protein 198
chr6_+_11646472 1.539 NM_001100829
TMEM170B
transmembrane protein 170B
chr16_-_30041767 1.537 MAPK3
mitogen-activated protein kinase 3
chr17_-_77094426 1.537 ACTG1
actin, gamma 1
chr15_-_63457378 1.536 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr1_+_153241858 1.535 ZBTB7B
zinc finger and BTB domain containing 7B
chr17_+_34114924 1.531 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr15_-_20637731 1.529 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr17_-_77094375 1.525 NM_001614
ACTG1
actin, gamma 1
chr19_+_47480445 1.523 NM_015125
CIC
capicua homolog (Drosophila)
chr22_-_17546276 1.522 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_-_38081967 1.509 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr16_-_960982 1.505 NM_022773
LMF1
lipase maturation factor 1
chr5_-_134397470 1.505 PITX1
paired-like homeodomain 1
chr14_+_104261578 1.503 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr11_+_279113 1.502 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr15_-_80125514 1.498 MEX3B
mex-3 homolog B (C. elegans)
chr2_-_174537021 1.497 NM_001017371
SP3
Sp3 transcription factor
chr17_+_73676219 1.497 NM_004710
SYNGR2
synaptogyrin 2
chr6_-_32268267 1.492 GPSM3
G-protein signaling modulator 3
chr16_-_51138306 1.489 NM_001080430
TOX3
TOX high mobility group box family member 3
chr7_-_86942910 1.484 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr4_-_1232742 1.476 CTBP1
C-terminal binding protein 1
chr19_+_34994701 1.457 NM_001238
CCNE1
cyclin E1
chr16_+_51722285 1.454 CHD9
chromodomain helicase DNA binding protein 9
chr14_+_104337923 1.450 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr12_+_6808025 1.449 LEPREL2
leprecan-like 2
chr16_+_2503676 1.448 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr5_+_176446425 1.440 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr2_-_200030944 1.432 NM_001172509
SATB2
SATB homeobox 2
chr20_+_60918836 1.430 NM_001853
COL9A3
collagen, type IX, alpha 3
chr17_+_45008473 1.403 NXPH3
neurexophilin 3
chr6_-_144427340 1.399 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr1_-_1233109 1.387 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr17_-_73636362 1.386 TMC6
transmembrane channel-like 6
chr7_-_102044374 1.384 RASA4
RAS p21 protein activator 4
chr11_+_117812282 1.379 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr10_+_124885556 1.373 NM_001105574
HMX3
H6 family homeobox 3
chr19_+_59061422 1.369 NM_001020820
MYADM
myeloid-associated differentiation marker
chr11_+_46358909 1.367 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr15_-_80125403 1.361 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr7_+_137795387 1.359 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr10_+_22649977 1.359 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr16_-_30042083 1.352 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr19_-_1763198 1.347 NM_001178002
NM_138813
ATP8B3

ATPase, aminophospholipid transporter, class I, type 8B, member 3

chr19_-_2672337 1.347 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr19_-_44034797 1.345 NM_001005335
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr15_+_39739933 1.345 MGA
MAX gene associated
chrX_-_2428579 1.342 NM_001171135
ZBED1
zinc finger, BED-type containing 1
chr9_-_131845277 1.340 NM_015033
FNBP1
formin binding protein 1
chr22_-_17546296 1.337 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_+_149707338 1.336 NM_173680
ZNF775
zinc finger protein 775
chr14_-_23090606 1.335 NM_033400
ZFHX2
zinc finger homeobox 2
chr14_-_76564374 1.334 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr19_-_2653662 1.329 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr2_+_218972963 1.328 NM_182642
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_+_16259812 1.325 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr14_-_90953883 1.324 NM_001080414
CCDC88C
coiled-coil domain containing 88C
chr19_+_1200882 1.320 MIDN
midnolin
chr2_+_218972721 1.315 NM_021198
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr12_-_120502483 1.312 NM_001005366
KDM2B
lysine (K)-specific demethylase 2B
chr10_+_111757675 1.305 NM_001121
NM_016824
ADD3

adducin 3 (gamma)

chr17_-_1336073 1.304 MYO1C
myosin IC
chr2_-_10506033 1.304 ODC1
ornithine decarboxylase 1
chr1_+_148389039 1.301 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr11_+_47236072 1.300 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr7_+_149696901 1.293 REPIN1
replication initiator 1
chr2_+_119905812 1.293 NM_183240
TMEM37
transmembrane protein 37
chr7_-_151764004 1.289 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr20_-_30535045 1.286 C20orf112
chromosome 20 open reading frame 112
chr15_+_39739864 1.286 NM_001080541
NM_001164273
MGA

MAX gene associated

chrX_+_128942435 1.285


chr16_-_1369613 1.285 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr5_-_175896829 1.278 NM_014901
RNF44
ring finger protein 44
chr12_+_54700955 1.275 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chrX_+_118776572 1.274 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr4_-_105635499 1.273 CXXC4
CXXC finger protein 4
chr15_+_38520594 1.270 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr19_+_8180179 1.268 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr2_+_242322645 1.268 NM_152783
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chrX_+_152643516 1.268 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr12_-_47679176 1.268 NM_015086
DDN
dendrin
chr7_-_102044419 1.265 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr17_+_72880831 1.259 NM_001113493
SEPT9
septin 9
chr6_+_163755658 1.257 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr9_+_130491370 1.254 SET
SET nuclear oncogene
chr19_+_54786723 1.253 NM_020719
PRR12
proline rich 12
chr17_+_44429748 1.249 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr2_-_61551350 1.245 NM_014709
USP34
ubiquitin specific peptidase 34
chr17_+_50698169 1.243 HLF
hepatic leukemia factor
chr17_-_45582872 1.239 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr14_+_20608179 1.235 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr9_-_131845077 1.235 FNBP1
formin binding protein 1
chr22_-_17546234 1.234 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr8_-_71478560 1.233 NM_006540
NCOA2
nuclear receptor coactivator 2
chr6_+_33486750 1.231 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr17_-_39651189 1.223 NM_014233
UBTF
upstream binding transcription factor, RNA polymerase I
chr1_+_945331 1.219 NM_198576
AGRN
agrin
chr2_-_96899326 1.217 SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr6_+_97479216 1.215 NM_052904
KLHL32
kelch-like 32 (Drosophila)
chr16_+_1979959 1.212 NM_004209
SYNGR3
synaptogyrin 3
chr14_-_20562962 1.207 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr22_+_27931685 1.203 NM_133455
EMID1
EMI domain containing 1
chr21_+_37661063 1.196 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr2_-_171725150 1.195 TLK1
tousled-like kinase 1
chr12_+_49443903 1.192 NM_005171
ATF1
activating transcription factor 1
chr19_-_44060729 1.190 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr3_-_10522221 1.188 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr2_-_96899396 1.185 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr7_-_100325209 1.184 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr1_-_11663762 1.179 NM_006341
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr2_+_200031333 1.178


chr6_+_7053183 1.176 RREB1
ras responsive element binding protein 1
chr2_+_171280182 1.175


chr22_+_20101661 1.175 NM_015094
HIC2
hypermethylated in cancer 2
chr17_+_26839143 1.172 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr17_-_71747867 1.171 NM_052916
RNF157
ring finger protein 157
chr16_-_30301357 1.170 SEPT1
septin 1
chr3_-_10522267 1.169 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr16_-_88295595 1.169 NM_152339
SPATA2L
spermatogenesis associated 2-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 3.68e-20 GO:0009987 cellular process
1.12 1.64e-16 GO:0044237 cellular metabolic process
1.14 3.08e-13 GO:0044260 cellular macromolecule metabolic process
1.10 3.51e-13 GO:0008152 metabolic process
1.11 3.69e-13 GO:0044238 primary metabolic process
1.33 1.34e-12 GO:0010605 negative regulation of macromolecule metabolic process
1.31 3.30e-12 GO:0009892 negative regulation of metabolic process
1.40 6.38e-12 GO:0010629 negative regulation of gene expression
1.19 8.53e-12 GO:0048519 negative regulation of biological process
1.09 2.71e-11 GO:0050794 regulation of cellular process
1.20 3.86e-11 GO:0048523 negative regulation of cellular process
1.17 4.84e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.09 1.77e-10 GO:0050789 regulation of biological process
1.30 1.24e-09 GO:0031324 negative regulation of cellular metabolic process
1.11 3.36e-09 GO:0043170 macromolecule metabolic process
1.36 3.57e-09 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 4.13e-09 GO:0045892 negative regulation of transcription, DNA-dependent
1.35 4.75e-09 GO:0051172 negative regulation of nitrogen compound metabolic process
1.14 4.91e-09 GO:0034641 cellular nitrogen compound metabolic process
1.14 5.14e-09 GO:0006807 nitrogen compound metabolic process
1.28 5.82e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.08 6.11e-09 GO:0065007 biological regulation
1.35 8.65e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.44 1.36e-08 GO:0016568 chromatin modification
1.34 1.37e-08 GO:0010558 negative regulation of macromolecule biosynthetic process
1.37 1.52e-08 GO:0051253 negative regulation of RNA metabolic process
1.17 1.64e-08 GO:0090304 nucleic acid metabolic process
1.14 2.06e-08 GO:0060255 regulation of macromolecule metabolic process
1.31 1.02e-07 GO:0009890 negative regulation of biosynthetic process
1.13 1.17e-07 GO:0031323 regulation of cellular metabolic process
1.13 1.35e-07 GO:0080090 regulation of primary metabolic process
1.41 1.51e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.21 1.52e-07 GO:0007399 nervous system development
1.27 3.00e-07 GO:0048699 generation of neurons
1.19 3.66e-07 GO:0016070 RNA metabolic process
1.30 4.49e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.11 4.90e-07 GO:0019222 regulation of metabolic process
1.19 6.27e-07 GO:0009059 macromolecule biosynthetic process
1.13 8.09e-07 GO:0016043 cellular component organization
1.19 1.16e-06 GO:0034645 cellular macromolecule biosynthetic process
1.25 1.42e-06 GO:0022008 neurogenesis
1.15 3.25e-06 GO:0044249 cellular biosynthetic process
1.14 4.89e-06 GO:0009058 biosynthetic process
1.12 4.99e-06 GO:0071840 cellular component organization or biogenesis
1.28 6.73e-06 GO:0030182 neuron differentiation
1.14 7.49e-06 GO:0071842 cellular component organization at cellular level
1.18 9.05e-06 GO:0023051 regulation of signaling
1.14 1.85e-05 GO:0010468 regulation of gene expression
1.16 2.32e-05 GO:0043412 macromolecule modification
1.24 2.43e-05 GO:0006351 transcription, DNA-dependent
1.16 2.95e-05 GO:0006464 protein modification process
1.13 3.80e-05 GO:0044267 cellular protein metabolic process
1.13 4.43e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.13 4.55e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.32 5.35e-05 GO:0006325 chromatin organization
1.50 6.73e-05 GO:0016569 covalent chromatin modification
1.10 6.81e-05 GO:0032502 developmental process
1.23 7.66e-05 GO:0048468 cell development
1.16 9.56e-05 GO:0010467 gene expression
1.21 9.72e-05 GO:0007049 cell cycle
1.50 9.75e-05 GO:0016570 histone modification
1.13 1.13e-04 GO:0048522 positive regulation of cellular process
1.28 1.23e-04 GO:0048666 neuron development
1.20 1.26e-04 GO:0051246 regulation of protein metabolic process
1.12 1.44e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 1.44e-04 GO:0009966 regulation of signal transduction
1.30 1.87e-04 GO:0031175 neuron projection development
1.11 2.18e-04 GO:0007275 multicellular organismal development
1.21 2.84e-04 GO:0032268 regulation of cellular protein metabolic process
1.14 4.24e-04 GO:0048869 cellular developmental process
1.13 4.63e-04 GO:0051252 regulation of RNA metabolic process
1.29 5.74e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.43 5.82e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.25 6.15e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.29 6.34e-04 GO:0048858 cell projection morphogenesis
1.12 7.36e-04 GO:0048518 positive regulation of biological process
1.25 8.59e-04 GO:0030030 cell projection organization
1.28 1.01e-03 GO:0032990 cell part morphogenesis
1.77 1.03e-03 GO:0018393 internal peptidyl-lysine acetylation
1.13 1.14e-03 GO:0030154 cell differentiation
1.34 1.18e-03 GO:0007411 axon guidance
1.75 1.30e-03 GO:0006475 internal protein amino acid acetylation
1.12 1.38e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 1.55e-03 GO:0007264 small GTPase mediated signal transduction
1.76 1.84e-03 GO:0016573 histone acetylation
1.33 2.10e-03 GO:0070647 protein modification by small protein conjugation or removal
1.29 2.26e-03 GO:0048812 neuron projection morphogenesis
1.74 2.29e-03 GO:0018394 peptidyl-lysine acetylation
1.10 2.47e-03 GO:0048856 anatomical structure development
1.19 2.67e-03 GO:0032774 RNA biosynthetic process
1.29 3.12e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.21 4.52e-03 GO:0031399 regulation of protein modification process
1.24 4.81e-03 GO:0051276 chromosome organization
1.11 5.27e-03 GO:0048731 system development
1.29 5.98e-03 GO:0007409 axonogenesis
1.11 6.56e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.22 6.99e-03 GO:0045595 regulation of cell differentiation
1.24 7.98e-03 GO:0000902 cell morphogenesis
1.23 8.27e-03 GO:0032989 cellular component morphogenesis
1.66 9.33e-03 GO:0006338 chromatin remodeling
1.36 9.55e-03 GO:0016567 protein ubiquitination
1.22 1.07e-02 GO:0009790 embryo development
1.19 1.14e-02 GO:0050793 regulation of developmental process
1.12 1.47e-02 GO:0006355 regulation of transcription, DNA-dependent
1.25 1.89e-02 GO:0000904 cell morphogenesis involved in differentiation
1.48 2.31e-02 GO:0051789 response to protein stimulus
1.29 2.46e-02 GO:0009792 embryo development ending in birth or egg hatching
1.29 2.51e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.17 2.77e-02 GO:0010646 regulation of cell communication
1.33 2.92e-02 GO:0032446 protein modification by small protein conjugation
1.10 3.20e-02 GO:0009889 regulation of biosynthetic process
1.10 3.28e-02 GO:0031326 regulation of cellular biosynthetic process
1.19 3.48e-02 GO:0051128 regulation of cellular component organization
1.26 3.60e-02 GO:0032583 regulation of gene-specific transcription
1.30 4.00e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.28 4.23e-02 GO:0043009 chordate embryonic development
1.13 4.73e-02 GO:0006996 organelle organization
1.57 4.75e-02 GO:0018205 peptidyl-lysine modification
1.61 4.78e-02 GO:0006473 protein acetylation
1.28 4.88e-02 GO:0018193 peptidyl-amino acid modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 1.06e-46 GO:0005622 intracellular
1.10 3.35e-44 GO:0044424 intracellular part
1.10 4.13e-30 GO:0043226 organelle
1.10 9.86e-30 GO:0043229 intracellular organelle
1.11 1.22e-29 GO:0043227 membrane-bounded organelle
1.11 3.97e-29 GO:0043231 intracellular membrane-bounded organelle
1.11 3.59e-27 GO:0005737 cytoplasm
1.14 6.85e-23 GO:0005634 nucleus
1.23 3.67e-17 GO:0044428 nuclear part
1.22 1.43e-16 GO:0070013 intracellular organelle lumen
1.21 5.86e-16 GO:0043233 organelle lumen
1.24 1.49e-15 GO:0031981 nuclear lumen
1.21 3.12e-15 GO:0031974 membrane-enclosed lumen
1.11 1.69e-14 GO:0044444 cytoplasmic part
1.21 1.71e-13 GO:0005829 cytosol
1.11 6.90e-13 GO:0044446 intracellular organelle part
1.11 1.07e-12 GO:0044422 organelle part
1.26 2.38e-12 GO:0005654 nucleoplasm
1.03 1.49e-08 GO:0005623 cell
1.03 1.80e-08 GO:0044464 cell part
1.28 2.52e-07 GO:0044451 nucleoplasm part
1.11 3.53e-05 GO:0043234 protein complex
1.10 6.32e-05 GO:0032991 macromolecular complex
1.27 8.87e-05 GO:0005694 chromosome
1.11 1.65e-04 GO:0043228 non-membrane-bounded organelle
1.11 1.65e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.63 2.32e-04 GO:0016585 chromatin remodeling complex
1.70 1.21e-03 GO:0000123 histone acetyltransferase complex
1.89 1.84e-03 GO:0000118 histone deacetylase complex
1.21 3.10e-03 GO:0015630 microtubule cytoskeleton
1.26 7.76e-03 GO:0043005 neuron projection
1.39 1.06e-02 GO:0043025 neuronal cell body
1.23 1.74e-02 GO:0044427 chromosomal part
1.36 2.84e-02 GO:0044297 cell body
1.34 3.70e-02 GO:0030425 dendrite
1.32 4.38e-02 GO:0000228 nuclear chromosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 3.09e-31 GO:0005515 protein binding
1.07 5.39e-24 GO:0005488 binding
1.30 3.67e-09 GO:0019899 enzyme binding
1.13 3.61e-08 GO:0003676 nucleic acid binding
1.24 7.57e-08 GO:0030528 transcription regulator activity
1.41 3.37e-06 GO:0008134 transcription factor binding
1.14 3.83e-06 GO:0003677 DNA binding
1.27 4.21e-06 GO:0043565 sequence-specific DNA binding
1.33 5.27e-06 GO:0019904 protein domain specific binding
1.21 4.57e-05 GO:0001071 nucleic acid binding transcription factor activity
1.21 4.57e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 1.36e-04 GO:0000988 protein binding transcription factor activity
1.33 1.36e-04 GO:0000989 transcription factor binding transcription factor activity
1.36 1.40e-04 GO:0016564 transcription repressor activity
1.32 1.83e-04 GO:0003712 transcription cofactor activity
1.43 6.32e-04 GO:0003682 chromatin binding
1.12 1.13e-03 GO:0000166 nucleotide binding
1.08 1.58e-02 GO:0043169 cation binding
1.08 1.64e-02 GO:0046872 metal ion binding
1.07 2.17e-02 GO:0043167 ion binding
1.18 2.22e-02 GO:0003723 RNA binding
1.11 2.45e-02 GO:0008270 zinc ion binding
1.18 2.95e-02 GO:0042802 identical protein binding
1.32 3.24e-02 GO:0019900 kinase binding