Motif ID: MZF1.p2

Z-value: 5.734


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_22513043 17.473 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr9_+_108665168 16.599 NM_021224
ZNF462
zinc finger protein 462
chr2_-_161058120 12.391 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_161058550 11.461 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_36531958 10.403 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr11_-_127897098 10.083 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_-_72521079 9.565


chr5_+_17270781 9.534 BASP1
brain abundant, membrane attached signal protein 1
chr7_-_27120015 8.926 HOXA3
homeobox A3
chr3_-_189354510 8.560 LOC339929
hypothetical LOC339929
chr2_-_216944911 8.333 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr10_-_105604942 8.285 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr3_-_121652183 8.240 NM_007085
FSTL1
follistatin-like 1
chr11_-_127897271 8.146 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr3_+_189354167 8.067 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_64504835 7.970 HMGA2
high mobility group AT-hook 2
chr6_-_10523203 7.885 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_-_126839000 7.698 CTBP2
C-terminal binding protein 2
chr22_-_28972683 7.620 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_75972473 7.499 COL12A1
collagen, type XII, alpha 1
chr4_-_158111916 7.384 PDGFC
platelet derived growth factor C
chr10_-_126839056 7.295 NM_001329
CTBP2
C-terminal binding protein 2
chr7_+_55054152 7.275 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr5_-_9599157 7.222 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chrX_+_73557809 7.138 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr4_-_158111995 7.096 NM_016205
PDGFC
platelet derived growth factor C
chr2_+_69093641 7.041 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr13_-_43259032 6.887 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr8_+_95722448 6.845 ESRP1
epithelial splicing regulatory protein 1
chr1_-_72520735 6.779 NM_173808
NEGR1
neuronal growth regulator 1
chr1_+_15957832 6.719 NM_017556
FBLIM1
filamin binding LIM protein 1
chr22_-_34566276 6.568 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr18_+_54682261 6.485 ZNF532
zinc finger protein 532
chr6_+_17501589 6.468 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr6_-_10523424 6.406 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_30361485 6.399 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr12_-_51912101 6.191 NM_000966
RARG
retinoic acid receptor, gamma
chr18_-_55515623 6.165 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr6_-_72187168 6.052 C6orf155
chromosome 6 open reading frame 155
chr10_+_73393998 6.026 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr18_-_55515552 5.986 CCBE1
collagen and calcium binding EGF domains 1
chr1_+_181259317 5.960


chr21_+_46226072 5.933 NM_001848
COL6A1
collagen, type VI, alpha 1
chr1_-_223907283 5.907 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chrX_+_100361588 5.894 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr3_+_23219707 5.727 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr1_+_162795328 5.715 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr2_-_56004366 5.549 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr13_-_39075200 5.511 LHFP
lipoma HMGIC fusion partner
chr5_-_92942680 5.471 FLJ42709
hypothetical LOC441094
chr21_-_27261276 5.457 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_-_24068759 5.419 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr22_-_34566210 5.406 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_-_14304036 5.405 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chrX_-_1291526 5.366 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr11_+_36354110 5.364 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr12_+_63958949 5.299 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr17_+_30594192 5.298 NM_144975
SLFN5
schlafen family member 5
chr4_+_81406765 5.295 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr20_+_51022352 5.244 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr4_+_30330963 5.228 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr22_-_34566367 5.219 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr20_+_17498507 5.218 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr6_-_10520592 5.176 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_18255753 5.156 FLJ35934
FLJ35934
chr6_-_10520264 5.154 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_95722575 5.137 ESRP1
epithelial splicing regulatory protein 1
chr17_+_58058783 5.114 MRC2
mannose receptor, C type 2
chr5_-_127901633 5.095 NM_001999
FBN2
fibrillin 2
chr8_+_95722516 5.073 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr12_-_47468985 5.062 NM_020983
ADCY6
adenylate cyclase 6
chr10_+_114699953 5.047 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_36436316 5.030 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_92944680 5.028 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr4_-_158111504 5.024 PDGFC
platelet derived growth factor C
chr5_-_73972055 4.947 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr12_-_105056577 4.931 NUAK1
NUAK family, SNF1-like kinase, 1
chr4_+_183302105 4.914 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr16_-_71650034 4.878 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_+_86189138 4.827 NM_007173
PRSS23
protease, serine, 23
chr7_-_27136876 4.809 NM_002141
HOXA4
homeobox A4
chr19_+_46416975 4.780 AXL
AXL receptor tyrosine kinase
chr4_-_11039600 4.758 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_-_126839546 4.753 NM_001083914
CTBP2
C-terminal binding protein 2
chr5_+_17270474 4.747 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr9_-_14303943 4.694 NFIB
nuclear factor I/B
chr19_-_242335 4.676 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr9_+_138341752 4.674 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr4_-_140696740 4.667 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_+_55054416 4.643 EGFR
epidermal growth factor receptor
chrX_+_154650590 4.633 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr9_-_14303899 4.580 NFIB
nuclear factor I/B
chr12_+_55201854 4.545 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr6_-_42527760 4.537 NM_033502
TRERF1
transcriptional regulating factor 1
chr5_+_82803248 4.521 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr19_-_242168 4.472 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr11_-_27677755 4.418 NM_170734
BDNF
brain-derived neurotrophic factor
chr12_+_63958689 4.394 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr9_-_4289574 4.387 GLIS3
GLIS family zinc finger 3
chr16_-_63713485 4.369 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr7_+_27102508 4.361


chr6_+_121798443 4.359 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_-_212791597 4.359 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_-_63713466 4.346 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_13240987 4.309 EMP1
epithelial membrane protein 1
chr16_-_63713382 4.298 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr17_-_24069299 4.277 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr14_+_85069217 4.254


chr19_+_12996745 4.227 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_+_77695334 4.192 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_+_181258952 4.148 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr19_+_46416938 4.136 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr17_-_69151821 4.132 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr10_+_71231693 4.125 COL13A1
collagen, type XIII, alpha 1
chr17_+_7728819 4.121 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr19_+_46416971 4.085 AXL
AXL receptor tyrosine kinase
chr6_+_116798791 4.084 NM_013352
DSE
dermatan sulfate epimerase
chr12_-_26169074 4.082 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_198975227 4.052 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr7_+_78920846 4.040 LOC100505881
hypothetical LOC100505881
chr4_+_30331289 4.034 PCDH7
protocadherin 7
chr9_+_111850770 4.033 AKAP2
A kinase (PRKA) anchor protein 2
chr13_+_113574925 4.030 NM_001143945
GAS6
growth arrest-specific 6
chr11_+_69165119 4.015 CCND1
cyclin D1
chr1_+_218768423 3.996 MARK1
MAP/microtubule affinity-regulating kinase 1
chr9_+_111850698 3.991 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr7_-_78920806 3.989 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_18003401 3.930 NM_005257
GATA6
GATA binding protein 6
chr12_+_74071145 3.920 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr22_+_29974368 3.909 LIMK2
LIM domain kinase 2
chr19_+_43572679 3.902 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr9_-_109291866 3.864 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_-_20684858 3.838 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_127458231 3.836 NM_022143
LRRC4
leucine rich repeat containing 4
chr4_-_115120251 3.831 NM_024590
ARSJ
arylsulfatase family, member J
chr10_-_35143900 3.825 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr13_+_72531098 3.808 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr9_-_4290028 3.803 NM_001042413
GLIS3
GLIS family zinc finger 3
chr22_-_26527469 3.795 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr8_+_123863224 3.778 ZHX2
zinc fingers and homeoboxes 2
chr1_-_85816520 3.760 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_+_69165065 3.747 CCND1
cyclin D1
chr4_-_86106567 3.735 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_199884152 3.710 NAV1
neuron navigator 1
chr12_-_94708641 3.710 NM_021229
NTN4
netrin 4
chr8_-_127639647 3.707 FAM84B
family with sequence similarity 84, member B
chr7_+_28415495 3.704 LOC401317
hypothetical LOC401317
chr19_+_46417117 3.687 AXL
AXL receptor tyrosine kinase
chr9_-_109291575 3.667 KLF4
Kruppel-like factor 4 (gut)
chr2_+_36436873 3.666 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_69165018 3.657 NM_053056
CCND1
cyclin D1
chr4_-_102487506 3.650 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_68470585 3.636 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr14_-_52487558 3.629 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr9_-_20612433 3.627 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_-_56178882 3.553 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr4_+_145786622 3.551 NM_022475
HHIP
hedgehog interacting protein
chr3_-_55496370 3.540 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr11_+_35596310 3.532 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr20_+_1823825 3.531 NM_001040023
SIRPA
signal-regulatory protein alpha
chr17_+_52026058 3.510 NM_005450
NOG
noggin
chr12_+_74071116 3.509 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr18_-_22382497 3.494 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr15_+_66658626 3.486 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr19_+_46417099 3.486 AXL
AXL receptor tyrosine kinase
chr2_+_5750229 3.478 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr20_+_1823534 3.471 SIRPA
signal-regulatory protein alpha
chr6_-_75972286 3.462 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr12_+_52618815 3.458 NM_017410
HOXC13
homeobox C13
chr20_+_1824006 3.456 SIRPA
signal-regulatory protein alpha
chr13_-_109236897 3.446 NM_003749
IRS2
insulin receptor substrate 2
chr12_-_94708477 3.440 NTN4
netrin 4
chr16_-_52877868 3.403 NM_024336
IRX3
iroquois homeobox 3
chr19_+_12996830 3.376 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_-_51406359 3.363 TCF4
transcription factor 4
chr8_-_11096257 3.343 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr12_-_93568336 3.334 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr7_+_114349376 3.323 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr12_+_13240983 3.309 EMP1
epithelial membrane protein 1
chr12_-_105165805 3.302 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr8_+_37672427 3.269 NM_025069
ZNF703
zinc finger protein 703
chr7_-_19123765 3.269 TWIST1
twist homolog 1 (Drosophila)
chr9_+_117955890 3.269 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_+_70952729 3.243 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr7_+_28692122 3.236 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_-_170441493 3.236 NM_005618
DLL1
delta-like 1 (Drosophila)
chr9_-_4289915 3.230 GLIS3
GLIS family zinc finger 3
chr10_+_71231649 3.227 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr2_+_85834111 3.197 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr2_-_207738858 3.187 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_143750988 3.186 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr18_+_44319365 3.172 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr20_+_1822943 3.165 SIRPA
signal-regulatory protein alpha
chr15_+_97010219 3.122 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr13_-_39075355 3.111 NM_005780
LHFP
lipoma HMGIC fusion partner
chrX_+_66680593 3.111 NM_000044
AR
androgen receptor
chr13_-_39075304 3.108 LHFP
lipoma HMGIC fusion partner
chr8_-_75396016 3.092 NM_020647
JPH1
junctophilin 1
chr2_+_28469864 3.074 FOSL2
FOS-like antigen 2
chrX_-_62891730 3.066 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.20e-22 GO:0009653 anatomical structure morphogenesis
1.08 6.38e-19 GO:0009987 cellular process
1.12 1.60e-18 GO:0065007 biological regulation
1.20 1.02e-17 GO:0032502 developmental process
1.13 1.29e-17 GO:0050794 regulation of cellular process
1.21 3.15e-17 GO:0007275 multicellular organismal development
1.12 5.36e-17 GO:0050789 regulation of biological process
1.26 5.75e-17 GO:0048522 positive regulation of cellular process
1.24 8.72e-17 GO:0048731 system development
1.22 1.75e-16 GO:0048856 anatomical structure development
1.33 5.94e-16 GO:0007399 nervous system development
1.24 7.25e-16 GO:0048518 positive regulation of biological process
1.42 1.54e-14 GO:0022008 neurogenesis
1.57 1.61e-14 GO:0000904 cell morphogenesis involved in differentiation
1.50 1.61e-14 GO:0032989 cellular component morphogenesis
1.27 2.13e-14 GO:0030154 cell differentiation
1.26 8.25e-14 GO:0048869 cellular developmental process
1.46 2.42e-13 GO:0030182 neuron differentiation
1.40 2.88e-13 GO:0048468 cell development
1.50 3.42e-13 GO:0000902 cell morphogenesis
1.40 1.69e-12 GO:0048699 generation of neurons
1.52 8.64e-12 GO:0031175 neuron projection development
1.17 1.32e-11 GO:0031323 regulation of cellular metabolic process
1.23 2.23e-11 GO:0048523 negative regulation of cellular process
1.47 2.66e-11 GO:0048666 neuron development
1.54 3.12e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.22 4.21e-11 GO:0048519 negative regulation of biological process
1.53 7.21e-11 GO:0048812 neuron projection morphogenesis
1.17 1.10e-10 GO:0080090 regulation of primary metabolic process
1.43 1.92e-10 GO:0030030 cell projection organization
1.53 3.06e-10 GO:0007409 axonogenesis
1.48 6.74e-10 GO:0048858 cell projection morphogenesis
1.17 7.10e-10 GO:0060255 regulation of macromolecule metabolic process
1.47 1.11e-09 GO:0032990 cell part morphogenesis
1.35 1.28e-09 GO:0050793 regulation of developmental process
1.13 2.26e-09 GO:0043170 macromolecule metabolic process
1.32 8.70e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.36 1.12e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.35 1.55e-08 GO:0051128 regulation of cellular component organization
1.15 1.72e-08 GO:0023052 signaling
1.19 1.99e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 3.01e-08 GO:0009790 embryo development
1.14 3.27e-08 GO:0019222 regulation of metabolic process
1.39 4.23e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 5.84e-08 GO:0044260 cellular macromolecule metabolic process
1.28 7.35e-08 GO:0031325 positive regulation of cellular metabolic process
1.35 7.41e-08 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 9.27e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.50 1.28e-07 GO:0043009 chordate embryonic development
1.37 1.31e-07 GO:0051254 positive regulation of RNA metabolic process
1.10 1.32e-07 GO:0044238 primary metabolic process
1.17 1.79e-07 GO:0031326 regulation of cellular biosynthetic process
1.17 1.82e-07 GO:0009889 regulation of biosynthetic process
1.49 2.18e-07 GO:0009792 embryo development ending in birth or egg hatching
1.26 2.24e-07 GO:0009893 positive regulation of metabolic process
1.38 2.62e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.21 4.69e-07 GO:0048513 organ development
1.17 4.93e-07 GO:0010468 regulation of gene expression
1.32 5.69e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.27 5.99e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.22 7.40e-07 GO:0023051 regulation of signaling
1.35 8.74e-07 GO:0010628 positive regulation of gene expression
1.31 1.01e-06 GO:0009891 positive regulation of biosynthetic process
1.33 1.11e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.42 1.11e-06 GO:0072358 cardiovascular system development
1.42 1.11e-06 GO:0072359 circulatory system development
1.33 1.11e-06 GO:2000026 regulation of multicellular organismal development
1.25 1.42e-06 GO:0051239 regulation of multicellular organismal process
1.24 1.64e-06 GO:0009966 regulation of signal transduction
1.34 2.07e-06 GO:0045595 regulation of cell differentiation
1.13 2.15e-06 GO:0051716 cellular response to stimulus
1.14 2.24e-06 GO:0007165 signal transduction
1.30 2.45e-06 GO:0031324 negative regulation of cellular metabolic process
1.16 2.53e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 3.14e-06 GO:0009887 organ morphogenesis
1.16 3.41e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.08 5.14e-06 GO:0008152 metabolic process
1.54 6.08e-06 GO:0001568 blood vessel development
1.27 6.92e-06 GO:0009892 negative regulation of metabolic process
1.17 1.12e-05 GO:0051252 regulation of RNA metabolic process
1.38 1.16e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 1.19e-05 GO:0071840 cellular component organization or biogenesis
1.13 2.17e-05 GO:0016043 cellular component organization
1.28 2.31e-05 GO:0009888 tissue development
1.28 2.44e-05 GO:0006351 transcription, DNA-dependent
1.49 3.31e-05 GO:0001944 vasculature development
1.26 3.79e-05 GO:0032879 regulation of localization
1.09 4.00e-05 GO:0044237 cellular metabolic process
1.48 4.06e-05 GO:0048729 tissue morphogenesis
1.15 4.62e-05 GO:0071842 cellular component organization at cellular level
1.45 5.12e-05 GO:0007411 axon guidance
1.27 5.23e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.15 8.04e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.38 8.67e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.18 1.09e-04 GO:0048583 regulation of response to stimulus
1.42 1.17e-04 GO:0048598 embryonic morphogenesis
1.32 1.25e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 1.27e-04 GO:0051094 positive regulation of developmental process
1.30 1.49e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.37 1.60e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.30 1.61e-04 GO:0009890 negative regulation of biosynthetic process
1.55 1.90e-04 GO:0001701 in utero embryonic development
1.29 1.97e-04 GO:0006468 protein phosphorylation
1.16 2.33e-04 GO:0006355 regulation of transcription, DNA-dependent
1.31 2.44e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 3.09e-04 GO:0035295 tube development
1.42 3.12e-04 GO:0007389 pattern specification process
1.50 4.19e-04 GO:0051129 negative regulation of cellular component organization
1.13 5.09e-04 GO:0019538 protein metabolic process
1.17 5.10e-04 GO:0006464 protein modification process
1.17 8.40e-04 GO:0010467 gene expression
1.25 1.33e-03 GO:0008219 cell death
1.42 1.54e-03 GO:0051130 positive regulation of cellular component organization
1.23 1.64e-03 GO:0032774 RNA biosynthetic process
1.30 1.98e-03 GO:0010629 negative regulation of gene expression
1.41 2.11e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.24 2.41e-03 GO:0016265 death
1.22 2.84e-03 GO:0032268 regulation of cellular protein metabolic process
1.13 3.07e-03 GO:0009058 biosynthetic process
1.13 3.09e-03 GO:0044267 cellular protein metabolic process
1.22 3.44e-03 GO:0006793 phosphorus metabolic process
1.22 3.44e-03 GO:0006796 phosphate metabolic process
1.58 4.01e-03 GO:0001655 urogenital system development
1.14 4.23e-03 GO:0044249 cellular biosynthetic process
1.39 4.24e-03 GO:0001501 skeletal system development
1.61 4.30e-03 GO:0060537 muscle tissue development
1.47 4.42e-03 GO:0002009 morphogenesis of an epithelium
1.26 4.49e-03 GO:0006915 apoptosis
1.16 5.11e-03 GO:0007166 cell surface receptor linked signaling pathway
1.45 5.79e-03 GO:0003002 regionalization
1.14 7.35e-03 GO:0042221 response to chemical stimulus
1.21 8.17e-03 GO:0009605 response to external stimulus
1.56 8.42e-03 GO:0045165 cell fate commitment
1.71 8.47e-03 GO:0030326 embryonic limb morphogenesis
1.71 8.47e-03 GO:0035113 embryonic appendage morphogenesis
1.36 8.49e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.83 8.86e-03 GO:0042326 negative regulation of phosphorylation
1.37 9.25e-03 GO:0045597 positive regulation of cell differentiation
1.41 1.04e-02 GO:0010608 posttranscriptional regulation of gene expression
1.16 1.04e-02 GO:0016070 RNA metabolic process
1.29 1.10e-02 GO:0051253 negative regulation of RNA metabolic process
1.61 1.10e-02 GO:0014706 striated muscle tissue development
1.29 1.12e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 1.15e-02 GO:0051246 regulation of protein metabolic process
1.23 1.17e-02 GO:0016310 phosphorylation
1.37 1.39e-02 GO:0051093 negative regulation of developmental process
1.25 1.41e-02 GO:0012501 programmed cell death
1.27 1.42e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.78 1.44e-02 GO:2000027 regulation of organ morphogenesis
1.14 1.47e-02 GO:0065008 regulation of biological quality
1.45 1.47e-02 GO:0048514 blood vessel morphogenesis
1.40 1.48e-02 GO:0061061 muscle structure development
1.27 1.58e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 1.59e-02 GO:0009059 macromolecule biosynthetic process
1.16 1.73e-02 GO:0034645 cellular macromolecule biosynthetic process
1.67 1.85e-02 GO:0003007 heart morphogenesis
1.63 1.87e-02 GO:0072001 renal system development
1.10 2.16e-02 GO:0051179 localization
1.33 2.31e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.31 2.34e-02 GO:0032583 regulation of gene-specific transcription
1.25 2.39e-02 GO:0042325 regulation of phosphorylation
1.26 2.59e-02 GO:0001932 regulation of protein phosphorylation
1.77 2.60e-02 GO:0010563 negative regulation of phosphorus metabolic process
1.77 2.60e-02 GO:0045936 negative regulation of phosphate metabolic process
1.57 2.89e-02 GO:0048705 skeletal system morphogenesis
1.40 3.05e-02 GO:0045596 negative regulation of cell differentiation
1.71 3.37e-02 GO:0048706 embryonic skeletal system development
1.14 3.47e-02 GO:0043412 macromolecule modification
1.24 3.50e-02 GO:0019220 regulation of phosphate metabolic process
1.24 3.50e-02 GO:0051174 regulation of phosphorus metabolic process
1.57 3.50e-02 GO:0010639 negative regulation of organelle organization
1.41 4.45e-02 GO:0048568 embryonic organ development
1.19 4.64e-02 GO:0010941 regulation of cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 5.08e-12 GO:0044424 intracellular part
1.06 2.47e-10 GO:0005622 intracellular
1.11 9.03e-09 GO:0005634 nucleus
1.08 1.56e-08 GO:0005737 cytoplasm
1.06 3.15e-08 GO:0043226 organelle
1.07 4.20e-08 GO:0043227 membrane-bounded organelle
1.07 5.05e-08 GO:0043231 intracellular membrane-bounded organelle
1.06 6.62e-08 GO:0043229 intracellular organelle
1.36 4.48e-07 GO:0030054 cell junction
1.03 9.42e-07 GO:0044464 cell part
1.03 1.04e-06 GO:0005623 cell
1.52 1.12e-05 GO:0016323 basolateral plasma membrane
1.16 1.78e-05 GO:0005829 cytosol
1.73 4.75e-05 GO:0030055 cell-substrate junction
1.60 1.04e-04 GO:0005912 adherens junction
1.74 1.06e-04 GO:0005925 focal adhesion
1.13 1.27e-04 GO:0043234 protein complex
1.72 1.54e-04 GO:0005924 cell-substrate adherens junction
1.16 2.43e-04 GO:0031981 nuclear lumen
1.53 5.87e-04 GO:0070161 anchoring junction
1.14 7.70e-04 GO:0044428 nuclear part
1.13 2.17e-03 GO:0043233 organelle lumen
1.32 2.28e-03 GO:0045202 synapse
1.10 2.63e-03 GO:0032991 macromolecular complex
1.17 6.35e-03 GO:0005654 nucleoplasm
1.12 7.52e-03 GO:0070013 intracellular organelle lumen
1.12 7.80e-03 GO:0031974 membrane-enclosed lumen
1.30 8.74e-03 GO:0043005 neuron projection
1.21 2.25e-02 GO:0044451 nucleoplasm part
1.43 2.31e-02 GO:0030424 axon
1.30 3.05e-02 GO:0048471 perinuclear region of cytoplasm
1.11 3.93e-02 GO:0044459 plasma membrane part
1.06 4.52e-02 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.91e-19 GO:0005515 protein binding
1.43 4.65e-12 GO:0043565 sequence-specific DNA binding
1.06 7.10e-11 GO:0005488 binding
1.33 1.54e-10 GO:0001071 nucleic acid binding transcription factor activity
1.33 1.54e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 3.28e-09 GO:0030528 transcription regulator activity
1.53 1.77e-04 GO:0010843 promoter binding
1.34 4.40e-04 GO:0019904 protein domain specific binding
1.50 5.33e-04 GO:0000975 regulatory region DNA binding
1.50 5.33e-04 GO:0001067 regulatory region nucleic acid binding
1.50 5.33e-04 GO:0044212 transcription regulatory region DNA binding
1.30 6.07e-04 GO:0008092 cytoskeletal protein binding
1.38 2.79e-03 GO:0008134 transcription factor binding
1.23 8.07e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 1.04e-02 GO:0019899 enzyme binding
1.22 1.63e-02 GO:0016301 kinase activity
1.92 1.89e-02 GO:0008013 beta-catenin binding
1.32 3.95e-02 GO:0003779 actin binding
1.23 4.65e-02 GO:0004672 protein kinase activity