Motif ID: NRF1.p2

Z-value: 4.697


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1



Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_2330594 3.237 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr6_-_39305203 3.061 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr13_-_78075683 2.897 NM_006237
POU4F1
POU class 4 homeobox 1
chr16_-_2330712 2.753 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_+_84385649 2.607 NM_021998
ZNF711
zinc finger protein 711
chr16_-_2330738 2.554 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_-_153360789 2.550 NM_006014
LAGE3
L antigen family, member 3
chr1_+_227473638 2.517 RAB4A
RAB4A, member RAS oncogene family
chr5_-_1647617 2.450 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr4_+_6726555 2.396 LOC93622
hypothetical LOC93622
chr6_-_31977747 2.362 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr12_-_52356123 2.328 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_+_165456572 2.325 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr22_-_30071761 2.301 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_60462152 2.278 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr1_-_247119516 2.272 NM_001136036
ZNF692
zinc finger protein 692
chr19_-_51097694 2.266 NM_001012643
MYPOP
Myb-related transcription factor, partner of profilin
chr1_+_148603208 2.132 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_-_52356375 2.129 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_31882558 2.126 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_+_27122796 2.125 NM_001145348
JMJD5
jumonji domain containing 5
chr11_-_65382313 2.056 NM_005507
CFL1
cofilin 1 (non-muscle)
chr6_+_30722794 2.055 NM_001109938
NM_001161376
NM_145029
C6orf136


chromosome 6 open reading frame 136


chr19_+_53559468 2.047 NM_012451
SYNGR4
synaptogyrin 4
chr7_-_149651594 2.033 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr19_-_6150536 2.025


chr7_+_149651481 2.019 LRRC61
leucine rich repeat containing 61
chr17_-_31281843 1.976 NM_001034836
NM_001163120
NM_001163121
NM_145654
RDM1



RAD52 motif 1



chr19_-_53558961 1.972 NM_018273
TMEM143
transmembrane protein 143
chr7_+_149651202 1.967 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr15_+_39739933 1.948 MGA
MAX gene associated
chr7_+_99865340 1.923 MEPCE
methylphosphate capping enzyme
chr4_-_1232742 1.873 CTBP1
C-terminal binding protein 1
chr1_+_227473458 1.867 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr15_+_39739864 1.857 NM_001080541
NM_001164273
MGA

MAX gene associated

chr19_+_1397268 1.853 APC2
adenomatosis polyposis coli 2
chr19_+_10392128 1.847 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_+_111515473 1.829 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr3_-_13436802 1.807 NM_024923
NUP210
nucleoporin 210kDa
chr22_-_37878394 1.798 NM_175709
CBX7
chromobox homolog 7
chr20_+_48781457 1.786 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr22_-_30072217 1.752 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr5_-_88215034 1.752 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr12_-_110935297 1.746 NM_001193453
NM_001193531
NM_138341
LOC728543
TMEM116


hypothetical protein LOC728543
transmembrane protein 116


chr17_-_24302597 1.744 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr19_+_60851207 1.730 CCDC106
coiled-coil domain containing 106
chr22_-_21193037 1.718 ZNF280B
zinc finger protein 280B
chr6_-_41148061 1.711 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr6_-_153346283 1.696 NM_001142522
FBXO5
F-box protein 5
chr4_+_6768800 1.692 CNO
cappuccino homolog (mouse)
chr5_+_137253023 1.682 NM_014386
PKD2L2
polycystic kidney disease 2-like 2
chr6_-_43651578 1.669 XPO5
exportin 5
chr4_+_6726699 1.666 LOC93622
hypothetical LOC93622
chr1_-_201124848 1.653 NM_002871
RABIF
RAB interacting factor
chr22_+_19078397 1.619 NM_003426
ZNF74
zinc finger protein 74
chr22_-_30071565 1.611 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr5_-_88214720 1.607 MEF2C
myocyte enhancer factor 2C
chr17_+_54652609 1.598 NM_001165993
NM_001165994
NM_182569
GDPD1


glycerophosphodiester phosphodiesterase domain containing 1


chr6_-_31882704 1.590 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_247119908 1.577 NM_001193328
NM_017865
ZNF692

zinc finger protein 692

chr11_-_65382228 1.571 CFL1
cofilin 1 (non-muscle)
chr17_-_24302450 1.567 PHF12
PHD finger protein 12
chr10_+_21863099 1.565 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr4_-_1232882 1.558 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chrX_-_133758812 1.554 NM_001166599
NM_001166600
NM_001170757
FAM122B


family with sequence similarity 122B


chr19_+_10932792 1.523 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr22_-_30072329 1.513 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_7874426 1.501


chr11_-_65382226 1.490


chr7_+_154426064 1.472 LOC202781
hypothetical LOC202781
chr19_-_11127451 1.470 NM_182513
SPC24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_+_18655483 1.470 CRTC1
CREB regulated transcription coactivator 1
chr1_-_21868380 1.467 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr9_+_132990760 1.461 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_229181203 1.460 TTC13
tetratricopeptide repeat domain 13
chr11_-_65382182 1.457 CFL1
cofilin 1 (non-muscle)
chr21_+_44377974 1.455 C21orf33
chromosome 21 open reading frame 33
chr19_-_55124546 1.452 NM_012346
NM_153718
NM_153719
NM_001193357
NM_172374
NUP62



IL4I1
nucleoporin 62kDa



interleukin 4 induced 1
chr6_-_43651727 1.446 XPO5
exportin 5
chr6_+_69401660 1.442 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr11_+_77528472 1.436 LOC100289388
hypothetical LOC100289388
chr6_+_33044378 1.433 NM_005104
BRD2
bromodomain containing 2
chr3_+_49566901 1.426 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr11_+_63829616 1.418 NM_004451
ESRRA
estrogen-related receptor alpha
chr1_-_40121756 1.416 NM_017646
TRIT1
tRNA isopentenyltransferase 1
chr1_-_154574671 1.404 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr4_+_6768682 1.397 NM_018366
CNO
cappuccino homolog (mouse)
chr1_-_16436032 1.394 NM_030907
RSG1
REM2 and RAB-like small GTPase 1
chr6_-_43651745 1.389 NM_020750
XPO5
exportin 5
chr19_+_7874701 1.385 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_+_33044353 1.381


chr6_+_24775241 1.374 NM_001160094
NM_018473
ACOT13

acyl-CoA thioesterase 13

chr9_+_132990834 1.373 NUP214
nucleoporin 214kDa
chrX_+_48907183 1.370 NM_001099680
MAGIX
MAGI family member, X-linked
chr12_+_52960745 1.366 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr1_-_154574595 1.366 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr1_-_154574688 1.363 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr1_-_1525309 1.358 LOC643988
hypothetical LOC643988
chr10_+_21863272 1.354 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_-_77528267 1.353 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr12_+_56202874 1.325 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr12_+_31118091 1.317 DDX11
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
chr1_+_244954153 1.317 SCCPDH
saccharopine dehydrogenase (putative)
chr11_+_62380042 1.315 NM_001012662
NM_001012664
NM_002394
NM_001012661
NM_001012663
SLC3A2




solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2




chr22_-_21193504 1.312 NM_080764
ZNF280B
zinc finger protein 280B
chr19_-_13877908 1.304 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr11_-_77528308 1.301 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr22_-_19543012 1.300 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr1_-_229181219 1.299 TTC13
tetratricopeptide repeat domain 13
chr20_-_55533544 1.299 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr6_+_41148869 1.299 NFYA
nuclear transcription factor Y, alpha
chr11_-_77528335 1.296 NM_001007027
NM_024079
ALG8

asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)

chr4_+_1232942 1.294 C4orf42
chromosome 4 open reading frame 42
chrX_-_153360411 1.293 LAGE3
L antigen family, member 3
chr19_+_54583286 1.291 NM_144688
CCDC155
coiled-coil domain containing 155
chr22_-_19543069 1.290 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr15_-_75711785 1.287 LINGO1
leucine rich repeat and Ig domain containing 1
chr19_+_10932583 1.285 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr11_-_77528318 1.281 ALG8
asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)
chr7_-_5536704 1.278 NM_001101
ACTB
actin, beta
chr9_+_130491291 1.274 NM_003011
SET
SET nuclear oncogene
chr18_-_5286013 1.273 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr1_-_154574716 1.271 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr6_+_135544214 1.266 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr7_+_99865189 1.266 NM_019606
MEPCE
methylphosphate capping enzyme
chr1_+_229181417 1.258 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr9_+_70509925 1.246 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_+_43651899 1.241 POLH
polymerase (DNA directed), eta
chr6_-_24774797 1.238 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chrX_-_153016173 1.233 MECP2
LOC728653
methyl CpG binding protein 2 (Rett syndrome)
hypothetical protein LOC728653
chr6_+_111515341 1.232 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr16_+_23754997 1.230 PRKCB
protein kinase C, beta
chr17_+_33706642 1.223 MRPL45
mitochondrial ribosomal protein L45
chr22_-_19686351 1.222 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr1_-_154574723 1.217 NM_001008800
NM_005998
CCT3

chaperonin containing TCP1, subunit 3 (gamma)

chr1_+_210275541 1.216 NM_016448
DTL
denticleless homolog (Drosophila)
chr19_+_7874774 1.213 MAP2K7
mitogen-activated protein kinase kinase 7
chr22_+_19543248 1.213 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr9_-_125070675 1.212 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr19_+_47416338 1.196 ZNF526
zinc finger protein 526
chr13_+_113287048 1.195 NM_007111
TFDP1
transcription factor Dp-1
chr22_+_22530040 1.194 NM_001024939
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr6_-_24775106 1.190 TDP2
tyrosyl-DNA phosphodiesterase 2
chr2_+_130655970 1.190 NM_025029
MZT2B
mitotic spindle organizing protein 2B
chr1_-_229181229 1.190 TTC13
tetratricopeptide repeat domain 13
chr11_-_62379788 1.185 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr6_-_35996915 1.183 NM_003137
SRPK1
SRSF protein kinase 1
chr16_+_87397686 1.182 NM_030928
CDT1
chromatin licensing and DNA replication factor 1
chr16_+_170334 1.180 NM_005331
HBQ1
hemoglobin, theta 1
chr16_+_27122307 1.172 NM_024773
JMJD5
jumonji domain containing 5
chr6_+_31815703 1.172 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6ORF26
MSH5



MSH5-C6orf26 read-through transcript
mutS homolog 5 (E. coli)



chr7_-_156125876 1.172 C7orf13
chromosome 7 open reading frame 13
chr6_-_35996794 1.170 SRPK1
SRSF protein kinase 1
chr20_-_57051231 1.167 NM_016045
SLMO2
slowmo homolog 2 (Drosophila)
chr19_+_55124211 1.165 NM_001193646
ATF5
activating transcription factor 5
chr19_+_18655487 1.160 CRTC1
CREB regulated transcription coactivator 1
chr1_-_1699723 1.160 NM_023018
NADK
NAD kinase
chr16_+_84204424 1.156 NM_014615
KIAA0182
KIAA0182
chr10_+_133995629 1.154 NM_001143757
LRRC27
leucine rich repeat containing 27
chr3_+_49701965 1.148 RNF123
ring finger protein 123
chr3_-_47492421 1.146 NM_012235
SCAP
SREBF chaperone
chr6_+_34312667 1.145 HMGA1
high mobility group AT-hook 1
chr12_+_110935534 1.145 NM_001034025
NM_006817
ERP29

endoplasmic reticulum protein 29

chr22_-_19543099 1.144 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr2_-_130655616 1.140 NM_001171083
NM_017751
NM_017951
SMPD4


sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)


chr15_-_41409979 1.135 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr7_+_156126157 1.130 NM_030936
NM_001184996
RNF32

ring finger protein 32

chr1_+_91739241 1.128 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr6_+_135544170 1.127 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr3_+_49701978 1.126 NM_022064
RNF123
ring finger protein 123
chr19_+_7874765 1.126 MAP2K7
mitogen-activated protein kinase kinase 7
chr16_+_29735208 1.125 C16orf53
chromosome 16 open reading frame 53
chr6_-_135417647 1.120 NM_001145158
NM_001145207
NM_006620
HBS1L


HBS1-like (S. cerevisiae)


chr1_-_19409328 1.120 NM_020765
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr22_+_19543350 1.119 SNAP29
synaptosomal-associated protein, 29kDa
chr8_+_144522389 1.118 NM_052924
RHPN1
rhophilin, Rho GTPase binding protein 1
chr9_+_133368092 1.116 NM_001077365
NM_001077366
NM_001136113
NM_001136114
NM_007171
POMT1




protein-O-mannosyltransferase 1




chr19_+_10932719 1.114 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr3_-_47492320 1.111 SCAP
SREBF chaperone
chr1_+_229181462 1.102 ARV1
ARV1 homolog (S. cerevisiae)
chr20_+_56989717 1.102 TH1L
TH1-like (Drosophila)
chr5_-_178983241 1.101 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr9_-_125070613 1.100 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr17_+_77478858 1.098 LOC92659
hypothetical LOC92659
chr19_-_55124491 1.098 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr1_+_32251988 1.095 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr18_+_3237527 1.093 NM_006471
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr21_+_33066281 1.092 C21orf49
chromosome 21 open reading frame 49
chr16_+_87164311 1.092 ZC3H18
zinc finger CCCH-type containing 18
chr19_-_55124764 1.091 NM_016553
NUP62
nucleoporin 62kDa
chr12_+_49728350 1.089 NM_001024668
NM_015416
LETMD1

LETM1 domain containing 1

chr5_+_162820094 1.089 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr19_+_7874762 1.088 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_48815853 1.087 NM_182498
ZNF428
zinc finger protein 428
chr15_+_41410163 1.085 NM_001012969
NM_001159280
ADAL

adenosine deaminase-like

chr19_+_7874820 1.085 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_31728418 1.084 BAG6
BCL2-associated athanogene 6
chr3_+_49702018 1.079 RNF123
ring finger protein 123
chr1_-_232681471 1.076 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chr3_+_43707362 1.071 NM_016006
ABHD5
abhydrolase domain containing 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 4.89e-32 GO:0044260 cellular macromolecule metabolic process
1.32 1.80e-24 GO:0044237 cellular metabolic process
1.65 2.26e-24 GO:0090304 nucleic acid metabolic process
1.37 8.87e-23 GO:0043170 macromolecule metabolic process
1.55 9.59e-23 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 2.93e-19 GO:0010467 gene expression
1.46 1.76e-18 GO:0034641 cellular nitrogen compound metabolic process
1.66 3.28e-18 GO:0016070 RNA metabolic process
1.44 6.43e-18 GO:0006807 nitrogen compound metabolic process
1.24 3.82e-16 GO:0008152 metabolic process
2.08 9.08e-16 GO:0006396 RNA processing
1.26 1.68e-15 GO:0044238 primary metabolic process
2.03 6.22e-14 GO:0051276 chromosome organization
1.43 5.25e-12 GO:0044267 cellular protein metabolic process
1.55 1.52e-11 GO:0006996 organelle organization
1.95 7.22e-10 GO:0016071 mRNA metabolic process
1.50 8.62e-10 GO:0034645 cellular macromolecule biosynthetic process
1.37 1.39e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.49 2.16e-09 GO:0009059 macromolecule biosynthetic process
1.79 5.87e-09 GO:0022403 cell cycle phase
1.96 1.16e-08 GO:0006325 chromatin organization
2.06 1.78e-08 GO:0006397 mRNA processing
1.35 5.77e-08 GO:0071842 cellular component organization at cellular level
1.95 8.39e-08 GO:0000279 M phase
1.40 4.03e-07 GO:0043412 macromolecule modification
1.35 4.55e-07 GO:0044249 cellular biosynthetic process
2.46 5.30e-07 GO:0051169 nuclear transport
1.77 1.04e-06 GO:0000278 mitotic cell cycle
2.45 1.05e-06 GO:0006913 nucleocytoplasmic transport
1.76 1.17e-06 GO:0006259 DNA metabolic process
2.33 1.68e-06 GO:0000375 RNA splicing, via transesterification reactions
1.95 2.91e-06 GO:0016568 chromatin modification
1.29 3.12e-06 GO:0019538 protein metabolic process
3.39 3.63e-06 GO:0006405 RNA export from nucleus
1.61 4.95e-06 GO:0022402 cell cycle process
2.31 5.03e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.31 5.03e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
1.09 5.10e-06 GO:0009987 cellular process
2.03 5.61e-06 GO:0008380 RNA splicing
1.53 9.56e-06 GO:0007049 cell cycle
1.31 9.94e-06 GO:0009058 biosynthetic process
2.08 1.05e-05 GO:0034660 ncRNA metabolic process
3.02 1.42e-05 GO:0051168 nuclear export
1.37 2.15e-05 GO:0006464 protein modification process
3.39 2.85e-05 GO:0006406 mRNA export from nucleus
1.98 3.29e-05 GO:0000087 M phase of mitotic cell cycle
1.24 7.09e-05 GO:0071840 cellular component organization or biogenesis
1.94 8.19e-05 GO:0006412 translation
1.95 1.27e-04 GO:0000280 nuclear division
1.95 1.27e-04 GO:0007067 mitosis
2.49 1.38e-04 GO:0006403 RNA localization
1.70 1.43e-04 GO:0006974 response to DNA damage stimulus
2.59 1.53e-04 GO:0051028 mRNA transport
2.51 1.70e-04 GO:0050657 nucleic acid transport
2.51 1.70e-04 GO:0050658 RNA transport
2.51 1.70e-04 GO:0051236 establishment of RNA localization
1.92 2.08e-04 GO:0048285 organelle fission
1.52 3.65e-04 GO:0033554 cellular response to stress
1.82 8.03e-04 GO:0006281 DNA repair
2.11 8.42e-04 GO:0034470 ncRNA processing
1.90 1.04e-03 GO:0032446 protein modification by small protein conjugation
1.22 1.29e-03 GO:0016043 cellular component organization
1.80 1.67e-03 GO:0070647 protein modification by small protein conjugation or removal
1.91 2.06e-03 GO:0016567 protein ubiquitination
1.50 2.11e-03 GO:0046907 intracellular transport
2.22 3.70e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.60 5.54e-03 GO:0044265 cellular macromolecule catabolic process
1.80 6.82e-03 GO:0006366 transcription from RNA polymerase II promoter
2.16 1.01e-02 GO:0006333 chromatin assembly or disassembly
1.53 1.02e-02 GO:0009057 macromolecule catabolic process
1.42 1.07e-02 GO:0032774 RNA biosynthetic process
1.91 2.26e-02 GO:0071843 cellular component biogenesis at cellular level
2.56 2.32e-02 GO:0031123 RNA 3'-end processing
1.92 2.76e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.34 2.88e-02 GO:0051641 cellular localization
2.04 3.24e-02 GO:0071103 DNA conformation change
1.98 3.46e-02 GO:0043687 post-translational protein modification
2.67 4.15e-02 GO:0031124 mRNA 3'-end processing
1.55 4.39e-02 GO:0034621 cellular macromolecular complex subunit organization
1.66 4.71e-02 GO:0051301 cell division
2.32 4.91e-02 GO:0016072 rRNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 1.70e-42 GO:0043231 intracellular membrane-bounded organelle
1.29 3.55e-42 GO:0043227 membrane-bounded organelle
1.25 5.32e-38 GO:0043226 organelle
1.25 5.64e-38 GO:0043229 intracellular organelle
1.19 7.97e-37 GO:0005622 intracellular
1.19 4.88e-36 GO:0044424 intracellular part
1.41 1.50e-35 GO:0005634 nucleus
1.65 1.04e-25 GO:0044428 nuclear part
1.63 7.72e-25 GO:0070013 intracellular organelle lumen
1.34 1.18e-24 GO:0044446 intracellular organelle part
1.60 1.63e-23 GO:0043233 organelle lumen
1.60 2.11e-23 GO:0031974 membrane-enclosed lumen
1.33 4.70e-23 GO:0044422 organelle part
1.67 2.89e-22 GO:0031981 nuclear lumen
1.71 4.01e-17 GO:0005654 nucleoplasm
2.00 8.03e-13 GO:0005694 chromosome
2.09 1.32e-12 GO:0044427 chromosomal part
1.33 1.09e-11 GO:0032991 macromolecular complex
2.44 1.55e-10 GO:0000785 chromatin
1.94 1.82e-10 GO:0030529 ribonucleoprotein complex
1.15 7.23e-09 GO:0005737 cytoplasm
1.31 1.28e-07 GO:0043228 non-membrane-bounded organelle
1.31 1.28e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.18 2.73e-07 GO:0044444 cytoplasmic part
1.43 5.43e-06 GO:0005739 mitochondrion
1.31 3.45e-05 GO:0005829 cytosol
1.53 1.53e-04 GO:0044451 nucleoplasm part
1.22 7.79e-04 GO:0043234 protein complex
1.04 2.27e-03 GO:0044464 cell part
1.04 2.36e-03 GO:0005623 cell
1.49 2.50e-03 GO:0044429 mitochondrial part
1.82 2.52e-03 GO:0005759 mitochondrial matrix
1.98 5.05e-03 GO:0044454 nuclear chromosome part
1.54 8.42e-03 GO:0005730 nucleolus
1.83 1.14e-02 GO:0000228 nuclear chromosome
2.43 1.15e-02 GO:0031461 cullin-RING ubiquitin ligase complex
2.04 1.62e-02 GO:0005681 spliceosomal complex
2.00 2.07e-02 GO:0000793 condensed chromosome
1.61 3.05e-02 GO:0005815 microtubule organizing center
1.84 3.28e-02 GO:0005840 ribosome
1.96 4.23e-02 GO:0000151 ubiquitin ligase complex
1.74 4.48e-02 GO:0005813 centrosome
2.35 4.50e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
3.52 4.99e-02 GO:0005680 anaphase-promoting complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 3.88e-18 GO:0003676 nucleic acid binding
1.86 1.10e-14 GO:0003723 RNA binding
1.19 5.37e-11 GO:0005515 protein binding
1.34 4.53e-07 GO:0000166 nucleotide binding
1.33 1.18e-06 GO:0003677 DNA binding
1.08 1.10e-05 GO:0005488 binding
1.16 2.38e-04 GO:0003824 catalytic activity
1.76 3.10e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.97 3.23e-03 GO:0003682 chromatin binding
1.80 3.35e-03 GO:0016881 acid-amino acid ligase activity
1.60 4.03e-03 GO:0016874 ligase activity
1.84 5.01e-03 GO:0019787 small conjugating protein ligase activity
1.28 6.58e-03 GO:0016740 transferase activity
1.64 7.46e-03 GO:0003712 transcription cofactor activity
1.63 8.25e-03 GO:0000988 protein binding transcription factor activity
1.63 8.25e-03 GO:0000989 transcription factor binding transcription factor activity
1.30 1.03e-02 GO:0005524 ATP binding
1.29 1.11e-02 GO:0030554 adenyl nucleotide binding
1.26 1.16e-02 GO:0035639 purine ribonucleoside triphosphate binding
2.52 1.29e-02 GO:0042393 histone binding
1.26 1.32e-02 GO:0017076 purine nucleotide binding
1.29 1.49e-02 GO:0032559 adenyl ribonucleotide binding
1.26 1.60e-02 GO:0032553 ribonucleotide binding
1.26 1.60e-02 GO:0032555 purine ribonucleotide binding
1.81 1.94e-02 GO:0004842 ubiquitin-protein ligase activity
1.76 4.59e-02 GO:0003713 transcription coactivator activity