Motif ID: PAX5.p2

Z-value: 2.918


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5



Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_61742111 8.083 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr13_-_43351825 5.530 NM_144974
CCDC122
coiled-coil domain containing 122
chr4_-_7991992 5.260 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr2_+_235525355 4.954 NM_014521
SH3BP4
SH3-domain binding protein 4
chr10_-_30064600 4.647 NM_003174
SVIL
supervillin
chr13_+_43351968 4.241 NM_153218
C13orf31
chromosome 13 open reading frame 31
chrX_+_43399101 4.134 MAOA
monoamine oxidase A
chr10_-_105604942 4.099 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr1_+_15957832 3.988 NM_017556
FBLIM1
filamin binding LIM protein 1
chr5_+_96023926 3.712 CAST
calpastatin
chr12_+_13044604 3.671 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr17_-_78199384 3.635 NM_019613
WDR45L
WDR45-like
chr3_-_133923992 3.597 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr21_+_32706615 3.470 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr13_-_105985313 3.338 NM_004093
EFNB2
ephrin-B2
chr1_-_223907283 3.325 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr4_-_177950658 3.273 NM_005429
VEGFC
vascular endothelial growth factor C
chr3_-_133923906 3.262 NM_153240
NPHP3
nephronophthisis 3 (adolescent)
chr3_+_133923758 3.231 NCRNA00119
non-protein coding RNA 119
chr2_+_238265617 3.166 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr12_-_13044467 3.103 NM_015987
HEBP1
heme binding protein 1
chr9_+_96807107 3.042 C9orf3
chromosome 9 open reading frame 3
chr7_+_55054416 2.999 EGFR
epidermal growth factor receptor
chr11_+_101485946 2.997 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr2_+_238265519 2.968 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr12_-_13044448 2.961 HEBP1
heme binding protein 1
chr12_-_13044314 2.924 HEBP1
heme binding protein 1
chr1_-_93919789 2.923 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr7_+_55054152 2.868 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr1_+_9275542 2.831 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr8_+_25097983 2.784 DOCK5
dedicator of cytokinesis 5
chr3_-_151171190 2.646 NM_002628
NM_053024
PFN2

profilin 2

chr14_-_52487386 2.625 FERMT2
fermitin family member 2
chr14_-_52487558 2.614 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr3_+_160964574 2.605 SCHIP1
schwannomin interacting protein 1
chr5_+_17270781 2.589 BASP1
brain abundant, membrane attached signal protein 1
chr2_+_159533329 2.552 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr1_+_9275518 2.523 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr8_-_13035102 2.496 NM_006094
DLC1
deleted in liver cancer 1
chr19_-_36531958 2.492 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr13_+_43845977 2.461 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr17_-_53387493 2.429 CUEDC1
CUE domain containing 1
chr8_-_13034873 2.353 DLC1
deleted in liver cancer 1
chr13_+_26029879 2.343 WASF3
WAS protein family, member 3
chr1_+_61980679 2.316 NM_176877
INADL
InaD-like (Drosophila)
chr2_-_36384 2.302 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr2_-_127694123 2.299 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_-_93568336 2.294 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr14_+_99329198 2.285 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr19_-_1518875 2.271 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr15_-_27901828 2.255 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr8_+_25098296 2.251 DOCK5
dedicator of cytokinesis 5
chr10_+_124124196 2.206 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_-_170428564 2.200 SH3RF1
SH3 domain containing ring finger 1
chr10_+_124124083 2.176 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_+_83130673 2.171 NM_001166392
TPBG
trophoblast glycoprotein
chr8_+_25098171 2.153 NM_024940
DOCK5
dedicator of cytokinesis 5
chr20_-_23566325 2.147 NM_000099
CST3
cystatin C
chrX_+_17665483 2.093 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr12_+_3056781 2.044 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr5_+_96023627 2.032 NM_001042440
CAST
calpastatin
chr12_-_105165805 2.031 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr4_-_170428681 2.025 SH3RF1
SH3 domain containing ring finger 1
chr4_-_158111995 2.021 NM_016205
PDGFC
platelet derived growth factor C
chr17_-_24068759 2.005 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr12_+_109046522 1.989 NM_001143779
NM_014055
NM_031473
IFT81


intraflagellar transport 81 homolog (Chlamydomonas)


chr15_+_71763773 1.975 CD276
CD276 molecule
chr11_+_12355600 1.962 NM_018222
PARVA
parvin, alpha
chr1_-_20684858 1.958 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr13_+_43351419 1.955 NM_001128303
C13orf31
chromosome 13 open reading frame 31
chr6_+_3696224 1.931


chr16_-_66827449 1.920 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr15_+_71763830 1.912 CD276
CD276 molecule
chr8_+_22513043 1.912 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr8_-_18915443 1.910 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_181259317 1.894


chr15_+_37660568 1.843 NM_003246
THBS1
thrombospondin 1
chr5_+_52320660 1.834 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr21_+_46226072 1.825 NM_001848
COL6A1
collagen, type VI, alpha 1
chr12_+_26003218 1.820 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr19_+_50041424 1.805 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_-_199704773 1.804 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr15_+_71763742 1.800 CD276
CD276 molecule
chr6_+_3697328 1.800


chr18_+_7557313 1.778 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr7_-_117300763 1.769 NM_033427
CTTNBP2
cortactin binding protein 2
chr6_-_138470160 1.769 NM_022121
PERP
PERP, TP53 apoptosis effector
chr6_-_56816403 1.768 DST
dystonin
chr6_+_139055244 1.764 FLJ46906
hypothetical LOC441172
chr1_-_22136263 1.763 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr19_+_15079141 1.748 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr7_-_107883929 1.730 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr6_-_3697244 1.727 NM_183373
C6orf145
chromosome 6 open reading frame 145
chr5_+_76047536 1.724 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr7_+_115926855 1.692 CAV2
caveolin 2
chr9_+_111850770 1.685 AKAP2
A kinase (PRKA) anchor protein 2
chr2_-_235070431 1.679 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr14_-_102593384 1.678 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr18_-_63334902 1.670 NM_032160
DSEL
dermatan sulfate epimerase-like
chr3_-_151171576 1.662 PFN2
profilin 2
chr3_+_151171755 1.658 LOC646903
hypothetical LOC646903
chr6_+_142664490 1.633 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr4_-_102487649 1.630 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr20_+_59260847 1.628 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr10_-_15250616 1.624 NM_004808
NMT2
N-myristoyltransferase 2
chr7_-_72771853 1.615 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr17_-_72218535 1.609 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr11_-_11987115 1.595 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr17_-_21395483 1.590 NM_001113434
C17orf51
chromosome 17 open reading frame 51
chr4_-_114902285 1.585 NM_001221
NM_172114
NM_172115
NM_172127
NM_172128
NM_172129
CAMK2D





calcium/calmodulin-dependent protein kinase II delta





chr20_-_49818306 1.583 NM_006045
ATP9A
ATPase, class II, type 9A
chr15_+_71763674 1.579 NM_001024736
NM_025240
CD276

CD276 molecule

chr20_-_17610704 1.577 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr2_+_241023908 1.564 GPC1
glypican 1
chr19_+_59062982 1.562 MYADM
myeloid-associated differentiation marker
chr5_+_96024434 1.559 CAST
calpastatin
chr9_-_83494198 1.558 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_-_128149112 1.554 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr17_-_75624048 1.546 NM_019020
TBC1D16
TBC1 domain family, member 16
chr4_-_158111504 1.534 PDGFC
platelet derived growth factor C
chr20_-_49818268 1.524 ATP9A
ATPase, class II, type 9A
chr2_+_241023703 1.524 NM_002081
GPC1
glypican 1
chrX_+_18353623 1.522 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr11_-_11987198 1.522 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr4_+_72271218 1.517 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr10_+_134972902 1.508


chr10_-_126839000 1.502 CTBP2
C-terminal binding protein 2
chrX_-_106846253 1.501 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr9_+_90193058 1.500 NM_006717
SPIN1
spindlin 1
chr19_+_39664706 1.493 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr11_+_109468734 1.482 ZC3H12C
zinc finger CCCH-type containing 12C
chr9_+_111850698 1.481 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr5_+_135392482 1.481 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr5_+_17270474 1.470 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr20_-_43410437 1.469 NM_002999
SDC4
syndecan 4
chr17_-_43470134 1.468 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr4_-_102487506 1.464 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_-_725522 1.462 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr7_+_1536847 1.461 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr13_-_20533629 1.450 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr4_+_3264509 1.447 RGS12
regulator of G-protein signaling 12
chr5_-_77980097 1.447 NM_005779
LHFPL2
lipoma HMGIC fusion partner-like 2
chr9_-_129370954 1.447 FAM129B
family with sequence similarity 129, member B
chr10_-_126839056 1.444 NM_001329
CTBP2
C-terminal binding protein 2
chr13_+_26029799 1.435 NM_006646
WASF3
WAS protein family, member 3
chr14_+_102128741 1.429 RCOR1
REST corepressor 1
chr17_+_40565492 1.427 NM_001135704
ACBD4
acyl-CoA binding domain containing 4
chr1_-_6468600 1.426 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_+_17389752 1.415 NM_001143942
RBM24
RNA binding motif protein 24
chr3_+_49211936 1.415 NM_001135197
CCDC36
coiled-coil domain containing 36
chr16_-_11588525 1.408 LITAF
lipopolysaccharide-induced TNF factor
chr10_-_71575953 1.408 TYSND1
trypsin domain containing 1
chr2_+_238265791 1.406 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr7_+_89678935 1.396 NM_152999
NM_001040665
STEAP2

six transmembrane epithelial antigen of the prostate 2

chr2_+_54536780 1.393 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr20_-_38751289 1.391 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr8_+_136538739 1.390 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr3_+_127118130 1.387 LOC100125556
family with sequence similarity 86, member A pseudogene
chr22_-_26527469 1.383 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr6_-_80713589 1.370 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr3_-_126257425 1.370 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr9_-_129371171 1.363 NM_022833
FAM129B
family with sequence similarity 129, member B
chr15_+_97009194 1.361 IGF1R
insulin-like growth factor 1 receptor
chr21_+_41461962 1.356 BACE2
beta-site APP-cleaving enzyme 2
chr4_-_170428768 1.353 NM_020870
SH3RF1
SH3 domain containing ring finger 1
chr5_+_175725050 1.348 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr4_-_122063118 1.347 NM_018699
PRDM5
PR domain containing 5
chr5_+_96023479 1.346 NM_001190442
CAST
calpastatin
chr21_+_45649429 1.345 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr14_+_104402626 1.340 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr7_+_44110470 1.339 NM_001129
AEBP1
AE binding protein 1
chr5_-_112658456 1.327 NM_002387
MCC
mutated in colorectal cancers
chr12_-_74711642 1.327 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_-_16989290 1.324 MYO10
myosin X
chr9_+_136673534 1.317 COL5A1
collagen, type V, alpha 1
chr7_-_117300702 1.305 CTTNBP2
cortactin binding protein 2
chr18_+_12298242 1.304 NM_032525
TUBB6
tubulin, beta 6
chr4_-_187881977 1.299 NM_005245
FAT1
FAT tumor suppressor homolog 1 (Drosophila)
chr5_+_14196287 1.289 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr14_+_54102518 1.285 LOC644925
hypothetical LOC644925
chr3_-_121652183 1.280 NM_007085
FSTL1
follistatin-like 1
chr8_+_8123513 1.279 FLJ10661
family with sequence similarity 86, member A pseudogene
chr6_-_10527772 1.276 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_16989371 1.275 NM_012334
MYO10
myosin X
chr6_-_150227063 1.266 NM_032832
LRP11
low density lipoprotein receptor-related protein 11
chr6_+_19945578 1.262 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_-_16710551 1.259 NM_030797
FAM49A
family with sequence similarity 49, member A
chr2_-_101134146 1.258 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr18_+_12298189 1.253 TUBB6
tubulin, beta 6
chr5_-_171814026 1.251 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr11_+_8059267 1.251 NM_177972
TUB
tubby homolog (mouse)
chr11_+_7997366 1.245 TUB
tubby homolog (mouse)
chr15_-_53667800 1.244 PYGO1
pygopus homolog 1 (Drosophila)
chr19_+_61798434 1.243 NM_021216
ZNF71
zinc finger protein 71
chr16_-_17472238 1.242 NM_022166
XYLT1
xylosyltransferase I
chr3_-_38046034 1.242 NM_006225
PLCD1
phospholipase C, delta 1
chr15_-_88159061 1.238 NM_001150
ANPEP
alanyl (membrane) aminopeptidase
chr15_+_61122139 1.237 TPM1
tropomyosin 1 (alpha)
chr1_-_65204414 1.235 NM_002227
JAK1
Janus kinase 1
chr3_-_49289285 1.227 NM_198562
C3orf62
chromosome 3 open reading frame 62

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.17 5.68e-26 GO:0050794 regulation of cellular process
1.15 2.15e-23 GO:0050789 regulation of biological process
1.14 4.19e-23 GO:0065007 biological regulation
1.09 4.83e-19 GO:0009987 cellular process
1.31 5.82e-18 GO:0048523 negative regulation of cellular process
1.35 2.69e-14 GO:0009966 regulation of signal transduction
1.21 5.87e-14 GO:0007165 signal transduction
1.20 1.36e-13 GO:0023052 signaling
1.26 1.63e-13 GO:0048519 negative regulation of biological process
1.31 4.09e-13 GO:0023051 regulation of signaling
1.18 3.09e-12 GO:0051716 cellular response to stimulus
1.21 4.44e-10 GO:0048518 positive regulation of biological process
1.22 8.10e-10 GO:0048522 positive regulation of cellular process
1.24 1.82e-08 GO:0048583 regulation of response to stimulus
1.17 3.93e-08 GO:0016043 cellular component organization
1.27 4.61e-08 GO:0009653 anatomical structure morphogenesis
1.24 5.61e-08 GO:0006464 protein modification process
1.41 6.68e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.11 7.59e-08 GO:0044237 cellular metabolic process
1.32 8.92e-08 GO:0010646 regulation of cell communication
1.43 1.26e-07 GO:0000902 cell morphogenesis
1.14 1.97e-07 GO:0044260 cellular macromolecule metabolic process
1.27 2.46e-07 GO:0035556 intracellular signal transduction
1.15 8.12e-07 GO:0071840 cellular component organization or biogenesis
1.39 9.08e-07 GO:0032989 cellular component morphogenesis
1.49 9.19e-07 GO:0009968 negative regulation of signal transduction
1.22 1.00e-06 GO:0043412 macromolecule modification
1.32 1.05e-06 GO:0022008 neurogenesis
1.26 1.34e-06 GO:0033036 macromolecule localization
1.39 1.60e-06 GO:0030030 cell projection organization
1.14 1.72e-06 GO:0019222 regulation of metabolic process
1.31 1.88e-06 GO:0032879 regulation of localization
1.25 2.00e-06 GO:0007399 nervous system development
1.36 2.60e-06 GO:0012501 programmed cell death
1.15 2.70e-06 GO:0060255 regulation of macromolecule metabolic process
1.32 3.30e-06 GO:0008219 cell death
1.49 3.42e-06 GO:0007264 small GTPase mediated signal transduction
1.15 3.90e-06 GO:0031323 regulation of cellular metabolic process
1.42 4.03e-06 GO:0032990 cell part morphogenesis
1.32 4.10e-06 GO:0016265 death
1.42 4.80e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.15 5.30e-06 GO:0080090 regulation of primary metabolic process
1.42 5.34e-06 GO:0048858 cell projection morphogenesis
1.28 5.59e-06 GO:0008104 protein localization
1.42 7.06e-06 GO:0000904 cell morphogenesis involved in differentiation
1.35 8.27e-06 GO:0006915 apoptosis
1.34 1.09e-05 GO:0016192 vesicle-mediated transport
1.81 1.21e-05 GO:0006470 protein dephosphorylation
1.11 1.31e-05 GO:0043170 macromolecule metabolic process
1.32 1.78e-05 GO:0051128 regulation of cellular component organization
1.43 1.86e-05 GO:0010648 negative regulation of cell communication
1.16 3.88e-05 GO:0071842 cellular component organization at cellular level
1.19 3.93e-05 GO:0048869 cellular developmental process
1.40 4.27e-05 GO:0031175 neuron projection development
1.42 4.27e-05 GO:0048812 neuron projection morphogenesis
1.17 4.88e-05 GO:0044267 cellular protein metabolic process
1.42 4.92e-05 GO:0023057 negative regulation of signaling
1.08 5.20e-05 GO:0008152 metabolic process
1.13 5.77e-05 GO:0032502 developmental process
1.30 5.87e-05 GO:0048699 generation of neurons
1.50 6.14e-05 GO:0060284 regulation of cell development
1.73 6.70e-05 GO:0016311 dephosphorylation
1.43 7.58e-05 GO:0007409 axonogenesis
1.09 9.17e-05 GO:0044238 primary metabolic process
1.28 1.52e-04 GO:0048468 cell development
1.14 1.56e-04 GO:0048856 anatomical structure development
1.38 1.62e-04 GO:0048585 negative regulation of response to stimulus
1.18 1.76e-04 GO:0030154 cell differentiation
1.26 2.01e-04 GO:0006793 phosphorus metabolic process
1.26 2.01e-04 GO:0006796 phosphate metabolic process
1.15 2.17e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.23 2.62e-04 GO:0051641 cellular localization
1.49 2.70e-04 GO:0051270 regulation of cellular component movement
1.40 2.97e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.13 3.43e-04 GO:0051179 localization
1.55 5.29e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.72 6.20e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.25 7.34e-04 GO:0043067 regulation of programmed cell death
1.13 7.70e-04 GO:0007275 multicellular organismal development
1.24 8.27e-04 GO:0010941 regulation of cell death
1.29 8.52e-04 GO:2000026 regulation of multicellular organismal development
1.71 9.39e-04 GO:0022604 regulation of cell morphogenesis
1.14 9.76e-04 GO:0048731 system development
1.33 1.29e-03 GO:0048666 neuron development
1.49 1.37e-03 GO:0030334 regulation of cell migration
1.18 1.47e-03 GO:0007166 cell surface receptor linked signaling pathway
1.46 1.54e-03 GO:0040012 regulation of locomotion
1.49 1.55e-03 GO:2000145 regulation of cell motility
1.26 1.56e-03 GO:0031324 negative regulation of cellular metabolic process
1.24 1.62e-03 GO:0042981 regulation of apoptosis
1.23 1.74e-03 GO:0051246 regulation of protein metabolic process
1.30 1.83e-03 GO:0045595 regulation of cell differentiation
1.79 2.32e-03 GO:0006643 membrane lipid metabolic process
1.26 2.41e-03 GO:0015031 protein transport
1.26 2.42e-03 GO:0045184 establishment of protein localization
1.13 2.53e-03 GO:0019538 protein metabolic process
1.25 2.83e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.24 3.78e-03 GO:0009892 negative regulation of metabolic process
1.81 3.89e-03 GO:0006665 sphingolipid metabolic process
1.46 4.04e-03 GO:0035295 tube development
1.23 6.00e-03 GO:0032268 regulation of cellular protein metabolic process
1.23 6.37e-03 GO:0007049 cell cycle
1.26 6.45e-03 GO:0046907 intracellular transport
1.28 6.73e-03 GO:0030182 neuron differentiation
1.24 7.68e-03 GO:0050793 regulation of developmental process
1.22 8.09e-03 GO:0051649 establishment of localization in cell
1.15 9.29e-03 GO:0065008 regulation of biological quality
1.31 1.03e-02 GO:0051253 negative regulation of RNA metabolic process
1.37 1.30e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.33 1.58e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.18 1.68e-02 GO:0065009 regulation of molecular function
1.27 1.69e-02 GO:0009890 negative regulation of biosynthetic process
1.19 1.70e-02 GO:0051239 regulation of multicellular organismal process
1.33 1.83e-02 GO:0060548 negative regulation of cell death
1.25 1.86e-02 GO:0031399 regulation of protein modification process
1.13 1.86e-02 GO:0010468 regulation of gene expression
1.31 1.88e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.46 1.90e-02 GO:0001558 regulation of cell growth
1.28 1.93e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.58 2.02e-02 GO:0034330 cell junction organization
1.28 2.13e-02 GO:0001932 regulation of protein phosphorylation
1.40 2.40e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.38 2.86e-02 GO:0007411 axon guidance
1.33 3.09e-02 GO:0043066 negative regulation of apoptosis
1.34 3.16e-02 GO:0008285 negative regulation of cell proliferation
1.54 3.34e-02 GO:0051272 positive regulation of cellular component movement
1.19 3.42e-02 GO:0009893 positive regulation of metabolic process
1.82 3.62e-02 GO:0050770 regulation of axonogenesis
1.20 3.83e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.33 3.88e-02 GO:0043069 negative regulation of programmed cell death
1.26 4.22e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.43 4.33e-02 GO:0050767 regulation of neurogenesis
1.30 4.33e-02 GO:0009967 positive regulation of signal transduction
1.25 4.69e-02 GO:0051049 regulation of transport
1.12 4.75e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.19 4.82e-02 GO:0031325 positive regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 7.26e-29 GO:0005622 intracellular
1.14 1.01e-27 GO:0005737 cytoplasm
1.10 5.42e-27 GO:0044424 intracellular part
1.15 2.27e-17 GO:0044444 cytoplasmic part
1.11 9.81e-17 GO:0043227 membrane-bounded organelle
1.10 3.36e-16 GO:0043231 intracellular membrane-bounded organelle
1.09 9.83e-16 GO:0043226 organelle
1.09 1.74e-15 GO:0043229 intracellular organelle
1.98 3.51e-12 GO:0005912 adherens junction
1.24 2.08e-11 GO:0005829 cytosol
1.87 2.23e-10 GO:0070161 anchoring junction
1.03 6.03e-10 GO:0005623 cell
1.03 7.77e-10 GO:0044464 cell part
1.33 2.34e-09 GO:0005794 Golgi apparatus
1.25 1.26e-08 GO:0012505 endomembrane system
1.12 1.61e-08 GO:0005634 nucleus
2.03 1.66e-08 GO:0005925 focal adhesion
1.98 2.36e-08 GO:0030055 cell-substrate junction
1.99 2.75e-08 GO:0005924 cell-substrate adherens junction
1.19 7.42e-07 GO:0031090 organelle membrane
1.67 2.55e-06 GO:0031252 cell leading edge
1.10 6.88e-06 GO:0044422 organelle part
1.10 1.38e-05 GO:0044446 intracellular organelle part
1.35 1.69e-05 GO:0044431 Golgi apparatus part
1.34 2.11e-05 GO:0030054 cell junction
1.37 6.92e-05 GO:0000139 Golgi membrane
1.29 3.49e-04 GO:0015630 microtubule cytoskeleton
1.48 7.27e-04 GO:0016323 basolateral plasma membrane
1.76 1.44e-03 GO:0001726 ruffle
1.14 2.52e-03 GO:0044459 plasma membrane part
1.73 3.96e-03 GO:0016327 apicolateral plasma membrane
1.39 4.38e-03 GO:0015629 actin cytoskeleton
1.66 6.42e-03 GO:0019898 extrinsic to membrane
1.72 7.97e-03 GO:0043296 apical junction complex
1.16 9.53e-03 GO:0005856 cytoskeleton
1.45 1.40e-02 GO:0005911 cell-cell junction
1.21 1.54e-02 GO:0042995 cell projection
1.29 2.16e-02 GO:0005768 endosome
1.32 3.78e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 3.81e-22 GO:0005515 protein binding
1.07 1.98e-16 GO:0005488 binding
1.46 4.04e-07 GO:0019904 protein domain specific binding
1.29 3.47e-06 GO:0030234 enzyme regulator activity
1.18 4.19e-06 GO:0000166 nucleotide binding
1.70 7.83e-06 GO:0004721 phosphoprotein phosphatase activity
1.38 3.60e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.37 1.38e-04 GO:0030695 GTPase regulator activity
1.17 3.04e-04 GO:0017076 purine nucleotide binding
1.17 3.56e-04 GO:0032553 ribonucleotide binding
1.17 3.56e-04 GO:0032555 purine ribonucleotide binding
1.41 4.93e-04 GO:0042578 phosphoric ester hydrolase activity
1.49 5.65e-04 GO:0016791 phosphatase activity
1.17 6.25e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.27 8.69e-04 GO:0019899 enzyme binding
1.23 1.15e-03 GO:0030528 transcription regulator activity
1.35 1.45e-03 GO:0004674 protein serine/threonine kinase activity
1.24 1.52e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.73 2.39e-03 GO:0004725 protein tyrosine phosphatase activity
1.31 2.52e-03 GO:0008092 cytoskeletal protein binding
3.14 4.83e-03 GO:0030275 LRR domain binding
1.23 1.39e-02 GO:0016301 kinase activity
1.63 1.59e-02 GO:0017124 SH3 domain binding
1.24 1.63e-02 GO:0042802 identical protein binding
1.57 3.38e-02 GO:0035091 phosphatidylinositol binding
1.35 3.97e-02 GO:0016563 transcription activator activity
1.23 4.88e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor