Motif ID: PRDM1.p3

Z-value: 3.159


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain



Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_16717887 8.062 BNC2
basonuclin 2
chr11_-_104344473 6.232 NM_001225
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr22_-_28972683 6.216 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr16_+_55580910 6.187 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr4_+_142777172 5.955 NM_000585
NM_172174
IL15

interleukin 15

chr6_-_112682401 5.454 LAMA4
laminin, alpha 4
chr6_-_112682459 5.239 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr17_+_6600080 5.089 XAF1
XIAP associated factor 1
chr3_-_115825742 4.895 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_32069183 4.551 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_-_189752575 4.531 NM_000393
COL5A2
collagen, type V, alpha 2
chr6_-_112682038 4.468 LAMA4
laminin, alpha 4
chr17_+_6599879 3.927 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr6_-_112682573 3.776 LAMA4
laminin, alpha 4
chr11_-_85107569 3.737 NM_206929
SYTL2
synaptotagmin-like 2
chr4_+_146623405 3.712 NM_001003688
SMAD1
SMAD family member 1
chr4_+_14985272 3.239 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr10_-_44200458 3.140 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr16_-_71650034 2.889 NM_001164766
ZFHX3
zinc finger homeobox 3
chr6_-_105691235 2.851 NM_007073
BVES
blood vessel epicardial substance
chr1_+_160868932 2.818 DDR2
discoidin domain receptor tyrosine kinase 2
chr3_+_8518539 2.810 LMCD1
LIM and cysteine-rich domains 1
chr17_-_45626364 2.752


chr8_-_23596346 2.726 NM_006167
NKX3-1
NK3 homeobox 1
chr1_-_111548440 2.615 DENND2D
DENN/MADD domain containing 2D
chr12_+_6431437 2.555 NM_018009
TAPBPL
TAP binding protein-like
chr16_+_49333513 2.503 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr3_+_8518508 2.502 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr16_+_49333461 2.499 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr21_-_34820916 2.438 NM_203418
RCAN1
regulator of calcineurin 1
chr10_+_63478974 2.424 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr8_-_145132551 2.400 PARP10
poly (ADP-ribose) polymerase family, member 10
chr17_+_3326045 2.342 NM_000049
ASPA
aspartoacylase
chr9_+_108665168 2.325 NM_021224
ZNF462
zinc finger protein 462
chr8_+_134272463 2.294 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr8_-_145132582 2.266 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr2_-_19421852 2.257 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr6_-_105691675 2.212 BVES
blood vessel epicardial substance
chr6_-_32919751 2.205 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr7_-_92301147 2.194 NM_001259
CDK6
cyclin-dependent kinase 6
chr8_-_79880095 2.188 NM_000880
IL7
interleukin 7
chr1_+_160868822 2.183 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr8_+_144711619 2.163 NM_024736
GSDMD
gasdermin D
chr4_+_187227302 2.134 NM_003265
TLR3
toll-like receptor 3
chr5_-_142795269 2.085 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr3_+_120495906 2.056 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr21_+_25856311 2.024 MIR155HG
MIR155 host gene (non-protein coding)
chr10_-_131652007 1.994 NM_001005463
EBF3
early B-cell factor 3
chr3_+_189354167 1.934 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_8518327 1.916 LOC100288428
hypothetical LOC100288428
chr2_+_205118801 1.852 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr14_-_68329407 1.847 NM_004926
ZFP36L1
zinc finger protein 36, C3H type-like 1
chr5_+_131774478 1.792 NM_001013717
C5orf56
chromosome 5 open reading frame 56
chr4_+_37569093 1.766 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_-_189354510 1.741 LOC339929
hypothetical LOC339929
chr3_-_49826221 1.720 UBA7
ubiquitin-like modifier activating enzyme 7
chr2_+_205118961 1.711 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr19_+_40931285 1.618 NM_019104
LIN37
lin-37 homolog (C. elegans)
chr9_+_136673464 1.607 NM_000093
COL5A1
collagen, type V, alpha 1
chr4_-_153523113 1.594 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr21_-_42219849 1.551 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr10_+_114126004 1.517 ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_+_97575071 1.516 SDC2
syndecan 2
chr15_-_40537002 1.505 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr10_+_114125955 1.502 ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_-_49826360 1.498 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr14_-_68332942 1.415 NM_207442
C14orf181
chromosome 14 open reading frame 181
chr10_+_114125927 1.375 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr22_-_34886727 1.344 NM_145640
APOL3
apolipoprotein L, 3
chr8_+_97575196 1.339 SDC2
syndecan 2
chr6_+_127481740 1.326 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chrX_+_102770547 1.275 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr8_+_97575052 1.271 NM_002998
SDC2
syndecan 2
chr19_-_23370066 1.261 NM_003430
ZNF91
zinc finger protein 91
chr15_+_68971835 1.240 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr2_+_230989114 1.231 NM_001080391
NM_003113
SP100

SP100 nuclear antigen

chr10_+_18469611 1.220 NM_201593
NM_201596
NM_201597
NM_001167945
NM_201571
NM_201572
CACNB2





calcium channel, voltage-dependent, beta 2 subunit





chr9_-_8723893 1.194 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr8_+_97575244 1.171 SDC2
syndecan 2
chr6_+_32919873 1.167


chr2_+_205118710 1.158 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr17_+_17339059 1.155


chr2_+_230989177 1.135 SP100
SP100 nuclear antigen
chr6_+_32929902 1.096 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr10_+_91051685 1.072 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr11_-_85108030 1.062 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr11_+_93501811 1.036 PANX1
pannexin 1
chr12_+_11694172 1.011 ETV6
ets variant 6
chr1_-_2486313 0.991 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr5_+_49998528 0.989 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chrX_-_62921937 0.966 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_+_102770303 0.954 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr9_+_18464138 0.949 ADAMTSL1
ADAMTS-like 1
chr9_+_111582317 0.941 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr11_-_40271086 0.928 LRRC4C
leucine rich repeat containing 4C
chr6_-_101018271 0.890 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr6_+_30018287 0.871 NM_002116
HLA-A
major histocompatibility complex, class I, A
chr3_-_11598829 0.860 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr2_-_230792844 0.852 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr14_+_23675233 0.832 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_152847256 0.822 ADAR
adenosine deaminase, RNA-specific
chr11_+_93501791 0.816 PANX1
pannexin 1
chr11_-_40272239 0.797 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr14_+_23675206 0.796 NM_006263
NM_176783
PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr11_-_786175 0.774 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_+_5602782 0.768 NM_021616
TRIM34
tripartite motif containing 34
chr9_+_96806235 0.767 C9orf3
chromosome 9 open reading frame 3
chr10_+_91082218 0.767 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr3_+_176059763 0.745 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr1_-_8406288 0.736 NM_001042682
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr1_+_2975590 0.733 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr2_+_230989150 0.729 SP100
SP100 nuclear antigen
chr9_+_119506428 0.718 TLR4
toll-like receptor 4
chr11_+_93501708 0.711 NM_015368
PANX1
pannexin 1
chr1_-_197173159 0.708 LOC100131234
familial acute myelogenous leukemia related factor
chr11_+_64946848 0.698


chr20_+_13924263 0.685 MACROD2
MACRO domain containing 2
chr20_-_5048443 0.680 NM_182649
PCNA
proliferating cell nuclear antigen
chr2_-_202216451 0.678 NM_001044385
ALS2CR4
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr4_-_48477021 0.671 FRYL
FRY-like
chr2_+_230900121 0.667 NM_138402
SP140L
SP140 nuclear body protein-like
chr12_-_54996098 0.663 NM_001190991
NM_014255
CNPY2

canopy 2 homolog (zebrafish)

chr7_+_134114957 0.658 CALD1
caldesmon 1
chr1_+_32438788 0.655 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr1_-_142536082 0.633


chr11_-_104411065 0.632 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr15_-_53996597 0.625 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_-_41641881 0.618 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr20_+_13924014 0.607 NM_080676
MACROD2
MACRO domain containing 2
chr7_+_134114701 0.605 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chrX_-_106248706 0.603 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr11_+_64946820 0.602 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_-_7998265 0.583 ERRFI1
ERBB receptor feedback inhibitor 1
chr6_-_32920167 0.571 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr6_+_127481496 0.563 RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr8_-_23768242 0.552 NM_003155
STC1
stanniocalcin 1
chr3_+_51951314 0.546 NM_001003931
NM_005485
PARP3

poly (ADP-ribose) polymerase family, member 3

chr1_-_152847301 0.541 NM_001111
NM_015840
NM_015841
ADAR


adenosine deaminase, RNA-specific


chr1_+_210848592 0.535 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr12_+_100795480 0.529 DRAM1
DNA-damage regulated autophagy modulator 1
chr10_+_69539255 0.524 NM_032578
MYPN
myopalladin
chr20_+_56904042 0.510 GNAS
GNAS complex locus
chr1_-_146398501 0.506 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr11_+_63060848 0.502 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr9_-_72926333 0.494 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr7_-_86686754 0.487 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr14_+_23982017 0.475


chr14_-_23981493 0.474 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr4_-_48477038 0.464 NM_015030
FRYL
FRY-like
chr8_-_42184350 0.463 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr13_+_30207690 0.462 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr12_-_54995923 0.461 CNPY2
canopy 2 homolog (zebrafish)
chr17_+_38412267 0.448 NM_005533
IFI35
interferon-induced protein 35
chr3_+_51952326 0.444 PARP3
poly (ADP-ribose) polymerase family, member 3
chr19_+_20138991 0.435 NM_052852
ZNF486
zinc finger protein 486
chr22_-_30018329 0.429 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr15_+_65245546 0.422 NM_001145104
SMAD3
SMAD family member 3
chr1_-_219982081 0.420 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr14_+_23771464 0.419 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr19_-_52427698 0.416 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr12_-_47605478 0.412 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr1_+_149638633 0.411 NM_002796
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr17_+_75851984 0.407


chr1_-_219982016 0.400 DUSP10
dual specificity phosphatase 10
chr12_-_54996044 0.398 CNPY2
canopy 2 homolog (zebrafish)
chr1_+_210848763 0.395 ATF3
activating transcription factor 3
chr2_-_191587128 0.393 STAT1
signal transducer and activator of transcription 1, 91kDa
chr4_+_86918882 0.392 ARHGAP24
Rho GTPase activating protein 24
chr12_+_120055013 0.392 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr8_-_143805371 0.379 LOC100288181
hypothetical LOC100288181
chr13_+_30207668 0.376 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr9_+_119506446 0.373 TLR4
toll-like receptor 4
chr1_-_219982049 0.369 DUSP10
dual specificity phosphatase 10
chr20_+_18396030 0.366 NM_006466
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chrX_-_100999204 0.364 NM_032946
NXF5
nuclear RNA export factor 5
chrX_-_106248674 0.361 RBM41
RNA binding motif protein 41
chr11_-_92570693 0.358 NM_152313
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr12_+_100795213 0.353 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr7_+_134483305 0.343 NM_018295
TMEM140
transmembrane protein 140
chr5_+_161209969 0.329 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_-_25044156 0.327 FAM65B
family with sequence similarity 65, member B
chr11_-_4371463 0.322 NM_003141
TRIM21
tripartite motif containing 21
chr10_+_123744131 0.321 TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_142535878 0.321 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr1_+_210848726 0.319 ATF3
activating transcription factor 3
chr13_-_109600709 0.316 COL4A1
collagen, type IV, alpha 1
chr11_-_56137553 0.314 NM_001004740
OR5M1
olfactory receptor, family 5, subfamily M, member 1
chr7_-_11643113 0.314 THSD7A
thrombospondin, type I, domain containing 7A
chr2_-_224611568 0.302 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr9_+_122890394 0.302 NM_007018
CEP110
centrosomal protein 110kDa
chr8_-_93144366 0.299 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_78000890 0.295 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr14_-_23771401 0.282 NM_006156
NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr12_+_53809731 0.281 NM_001005243
OR9K2
olfactory receptor, family 9, subfamily K, member 2
chr3_+_115099007 0.274 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr19_+_54669629 0.269 FLT3LG
fms-related tyrosine kinase 3 ligand
chr9_-_34700062 0.269 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr7_+_89681069 0.263 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr21_+_42807052 0.262 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr15_-_78050515 0.260 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
12.43 1.34e-06 GO:0060337 type I interferon-mediated signaling pathway
12.43 1.34e-06 GO:0071357 cellular response to type I interferon
12.24 1.60e-06 GO:0034340 response to type I interferon
5.72 7.97e-05 GO:0019221 cytokine-mediated signaling pathway
4.05 1.64e-04 GO:0045087 innate immune response
2.95 2.45e-04 GO:0006955 immune response
2.43 2.88e-04 GO:0002376 immune system process
5.16 3.09e-04 GO:0071345 cellular response to cytokine stimulus
5.92 4.09e-04 GO:0009615 response to virus
2.69 7.18e-04 GO:0051704 multi-organism process
2.74 1.16e-03 GO:0006952 defense response
2.53 1.68e-03 GO:0009892 negative regulation of metabolic process
2.88 1.73e-03 GO:0002682 regulation of immune system process
2.60 2.18e-03 GO:0031324 negative regulation of cellular metabolic process
2.57 2.79e-03 GO:0010605 negative regulation of macromolecule metabolic process
3.51 3.02e-03 GO:0051707 response to other organism
2.89 4.21e-03 GO:0071310 cellular response to organic substance
3.18 4.26e-03 GO:0009607 response to biotic stimulus
10.22 6.12e-03 GO:0032479 regulation of type I interferon production
1.79 1.11e-02 GO:0048522 positive regulation of cellular process
3.72 1.79e-02 GO:0034097 response to cytokine stimulus
7.10 2.07e-02 GO:0043900 regulation of multi-organism process
3.82 2.55e-02 GO:0001817 regulation of cytokine production
6.84 2.73e-02 GO:0045637 regulation of myeloid cell differentiation
2.46 2.99e-02 GO:0006508 proteolysis
3.35 3.35e-02 GO:0044419 interspecies interaction between organisms
20.02 4.45e-02 GO:0032728 positive regulation of interferon-beta production

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
6.68 4.75e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
21.56 5.66e-03 GO:0001530 lipopolysaccharide binding
4.17 1.59e-02 GO:0005126 cytokine receptor binding
2.60 2.22e-02 GO:0008233 peptidase activity
2.56 4.04e-02 GO:0070011 peptidase activity, acting on L-amino acid peptides
13.35 4.33e-02 GO:0004298 threonine-type endopeptidase activity
13.35 4.33e-02 GO:0070003 threonine-type peptidase activity