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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: RREB1.p2

Z-value: 2.342

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_96924582	5.562	NM_001172667	FAM178B	family with sequence similarity 178, member B
chrX_+_151617900	4.337	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chrX_-_151688850	4.255	NM_005362	MAGEA3	melanoma antigen family A, 3
chr1_-_30977931	3.703		LAPTM5	lysosomal protein transmembrane 5
chrX_-_151653756	2.973	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chr11_-_74740298	2.894	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chrX_+_151653874	2.740	NM_001102576 NM_153478	CSAG1	chondrosarcoma associated gene 1
chrX_+_151633730	2.727	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr7_-_100331417	2.414	NM_000665 NM_015831	ACHE	acetylcholinesterase
chrX_-_152139267	2.347	NM_004988	MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr17_-_44058612	2.319	NM_024017	HOXB9	homeobox B9
chr14_+_28305922	2.311	NM_005249	FOXG1	forkhead box G1
chrX_-_151672985	2.307	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr4_-_109308893	2.204	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr22_-_21231421	1.924	NM_206955 NM_206956 NM_006115 NM_206953 NM_206954	PRAME	preferentially expressed antigen in melanoma
chr1_-_154318412	1.865	NM_001093725	MEX3A	mex-3 homolog A (C. elegans)
chr20_-_22512893	1.856		FOXA2	forkhead box A2
chr20_-_55533544	1.856	NM_080618	CTCFL	CCCTC-binding factor (zinc finger protein)-like
chr1_-_182273114	1.618		GLT25D2	glycosyltransferase 25 domain containing 2
chr12_+_54700955	1.612	NM_022465	IKZF4	IKAROS family zinc finger 4 (Eos)
chr19_+_659766	1.604	NM_001040134 NM_002579	PALM	paralemmin
chr13_-_113066366	1.574	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr22_+_19699441	1.537	NM_001159554 NM_005446	P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6
chr20_-_22513050	1.529	NM_021784	FOXA2	forkhead box A2
chr2_+_200031333	1.504
chr15_+_74416156	1.496	NM_145805	ISL2	ISL LIM homeobox 2
chr8_+_144706699	1.468	NM_001166237	GSDMD	gasdermin D
chr4_-_809879	1.451	NM_006651	CPLX1	complexin 1
chr19_-_8581559	1.444	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr19_+_60487345	1.438	NM_032430	BRSK1	BR serine/threonine kinase 1
chr15_+_74416129	1.425		ISL2	ISL LIM homeobox 2
chr21_-_43369492	1.422	NM_001178008 NM_001178009	CBS	cystathionine-beta-synthase
chr13_-_113066202	1.409		GRTP1	growth hormone regulated TBC protein 1
chr7_-_100077072	1.396	NM_003227	TFR2	transferrin receptor 2
chr20_+_48032918	1.389	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr21_-_43368963	1.387	NM_000071	CBS	cystathionine-beta-synthase
chr12_+_6807831	1.373	NM_014262	LEPREL2	leprecan-like 2
chr12_-_52980914	1.364		NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr1_-_1283770	1.363	NM_032348	MXRA8	matrix-remodelling associated 8
chr12_-_52980984	1.355	NM_001136023	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr5_+_176446425	1.334	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr20_-_62151216	1.326	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr7_+_150390566	1.316		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr9_-_122679387	1.284	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr19_+_14405216	1.280		PKN1	protein kinase N1
chr9_-_122679283	1.273		PHF19	PHD finger protein 19
chr11_+_46359821	1.265		MDK	midkine (neurite growth-promoting factor 2)
chr2_+_174907914	1.263	NM_001145250	SP9	Sp9 transcription factor homolog (mouse)
chr11_+_46359855	1.262		MDK	midkine (neurite growth-promoting factor 2)
chr7_-_150305933	1.245	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_+_14032655	1.235	NM_001165034	RNF182	ring finger protein 182
chr19_+_811615	1.227		CFD	complement factor D (adipsin)
chr16_+_86193993	1.199	NM_020655	JPH3	junctophilin 3
chr5_+_6501735	1.189	NM_001145161	UBE2QL1	ubiquitin-conjugating enzyme E2Q family-like 1
chr11_+_46359836	1.181		MDK	midkine (neurite growth-promoting factor 2)
chr12_+_56135353	1.136	NM_031479	INHBE	inhibin, beta E
chr6_-_29703725	1.130		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_60350122	1.111		TNNT1	troponin T type 1 (skeletal, slow)
chr19_+_60487578	1.093		BRSK1	BR serine/threonine kinase 1
chr17_+_77582774	1.089	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_-_44010543	1.088	NM_024015	HOXB4	homeobox B4
chr16_+_29725311	1.085	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_139008667	1.067		CXXC5	CXXC finger protein 5
chr16_-_69030421	1.059	NM_006927	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr6_+_42857540	1.056		KIAA0240	KIAA0240
chr17_+_63252704	1.053		BPTF	bromodomain PHD finger transcription factor
chr2_-_220144511	1.049	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chrX_-_39841599	1.047	NM_001123385 NM_017745	BCOR	BCL6 corepressor
chr14_-_20563698	1.032		NDRG2	NDRG family member 2
chr9_+_129962292	1.026	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr2_-_119322228	1.018	NM_001426	EN1	engrailed homeobox 1
chr5_-_176833197	1.015		DBN1	drebrin 1
chr11_+_46359878	1.015	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr9_-_126945536	1.006	NM_001144877 NM_173690	SCAI	suppressor of cancer cell invasion
chr5_+_139008139	1.005		CXXC5	CXXC finger protein 5
chr17_-_73636362	1.005		TMC6	transmembrane channel-like 6
chr11_+_46359781	1.003	NM_002391	MDK	midkine (neurite growth-promoting factor 2)
chrX_-_153632355	1.001	NM_001081573 NM_080612	GAB3	GRB2-associated binding protein 3
chr17_+_1580504	0.999		WDR81	WD repeat domain 81
chr2_+_181553613	0.998		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_14405100	0.987	NM_002741	PKN1	protein kinase N1
chr17_-_77474597	0.982	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chrX_-_148476903	0.982	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr10_+_21863099	0.976	NM_001195627 NM_001195628 NM_001195630 NM_004641	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr21_-_46428728	0.969		C21orf56	chromosome 21 open reading frame 56
chr9_+_70509925	0.968	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_+_32229599	0.957	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr2_-_200030944	0.955	NM_001172509	SATB2	SATB homeobox 2
chr12_-_21818881	0.951	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr17_-_73636386	0.947	NM_001127198	TMC6	transmembrane channel-like 6
chr7_-_150411345	0.946	NM_031434	TMUB1	transmembrane and ubiquitin-like domain containing 1
chr21_-_46428768	0.936		C21orf56	chromosome 21 open reading frame 56
chr16_+_84202515	0.930	NM_001134473	KIAA0182	KIAA0182
chr14_-_20563722	0.928	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr3_+_20056527	0.925	NM_003884	KAT2B	K(lysine) acetyltransferase 2B
chr6_-_35572694	0.918	NM_003214	TEAD3	TEA domain family member 3
chr10_-_76538859	0.918	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr15_+_41597097	0.912	NM_002373	MAP1A	microtubule-associated protein 1A
chr2_-_130603264	0.904	NM_001099771	POTEF	POTE ankyrin domain family, member F
chr3_-_159306214	0.902
chr17_+_75366524	0.886	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr1_+_20385164	0.886	NM_152376	UBXN10	UBX domain protein 10
chrX_+_152561086	0.884	NM_001395	DUSP9	dual specificity phosphatase 9
chrX_+_119176494	0.882	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chrX_+_117513899	0.877	NM_144658	DOCK11	dedicator of cytokinesis 11
chr6_+_32229771	0.864		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr14_-_21064182	0.857		SALL2	sal-like 2 (Drosophila)
chr21_-_10120690	0.855	NM_001187 NM_182484 NM_181704 NM_182481 NM_182482	BAGE BAGE5 BAGE4 BAGE3 BAGE2	B melanoma antigen B melanoma antigen family, member 5 B melanoma antigen family, member 4 B melanoma antigen family, member 3 B melanoma antigen family, member 2
chr16_-_28515868	0.852	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_+_56202874	0.850	NM_052897	MBD6	methyl-CpG binding domain protein 6
chr3_+_20056857	0.848		KAT2B	K(lysine) acetyltransferase 2B
chr21_-_46428788	0.837	NM_001142854 NM_032261	C21orf56	chromosome 21 open reading frame 56
chr3_+_148593911	0.835
chr1_+_945331	0.830	NM_198576	AGRN	agrin
chr6_+_32230172	0.827		PPT2	palmitoyl-protein thioesterase 2
chr5_+_665454	0.827		CEP72	centrosomal protein 72kDa
chrX_-_11194015	0.825	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr3_-_71715431	0.822	NM_001012505 NM_032682	FOXP1	forkhead box P1
chr11_+_279113	0.814	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr2_-_144994349	0.814	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr5_+_665404	0.812	NM_018140	CEP72	centrosomal protein 72kDa
chr7_-_733401	0.803	NM_001164760	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr5_+_139008091	0.799		CXXC5	CXXC finger protein 5
chr19_+_17723285	0.793	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr11_-_32413486	0.789		WT1	Wilms tumor 1
chr2_+_181553333	0.778	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr7_+_733182	0.772		HEATR2	HEAT repeat containing 2
chr19_+_540849	0.770	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr19_-_55763091	0.761	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr5_-_134397740	0.760	NM_002653	PITX1	paired-like homeodomain 1
chr1_-_200397300	0.756		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr10_-_75085754	0.753	NM_001114133	SYNPO2L	synaptopodin 2-like
chr19_+_12805747	0.751		MAST1	microtubule associated serine/threonine kinase 1
chr19_-_60350118	0.751		TNNT1	troponin T type 1 (skeletal, slow)
chr16_+_66022520	0.742	NM_000196	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2
chr14_+_104267270	0.742	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr5_+_76181581	0.741	NM_130772	S100Z	S100 calcium binding protein Z
chr19_-_7896974	0.741	NM_206833	CTXN1	cortexin 1
chrX_-_119095544	0.740	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chr2_+_42128521	0.740	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr2_-_144994038	0.739		ZEB2	zinc finger E-box binding homeobox 2
chr12_+_56291484	0.739	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_149214063	0.738	NM_022075 NM_181746	LASS2	LAG1 homolog, ceramide synthase 2
chr2_+_181553783	0.737		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_40213431	0.734	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr7_-_148211533	0.733		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr6_+_4721825	0.732		CDYL	chromodomain protein, Y-like
chrX_+_148671394	0.730	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr9_+_138760432	0.720		LOC100128593	hypothetical LOC100128593
chr15_-_80125403	0.716	NM_032246	MEX3B	mex-3 homolog B (C. elegans)
chr1_-_2115950	0.715	NM_182533	C1orf86	chromosome 1 open reading frame 86
chr19_+_10261646	0.709	NM_003259	ICAM5	intercellular adhesion molecule 5, telencephalin
chr14_-_20562962	0.706	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr6_-_29703913	0.704	NM_021903	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr14_-_90352513	0.702	NM_001010854	TTC7B	tetratricopeptide repeat domain 7B
chr2_-_144991556	0.700		ZEB2	zinc finger E-box binding homeobox 2
chr7_-_150306169	0.699		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_-_187025438	0.698		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr12_-_47679176	0.697	NM_015086	DDN	dendrin
chrX_-_153534951	0.686	NM_020994 NM_172377	CTAG2	cancer/testis antigen 2
chr3_-_185578621	0.685	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr16_+_84204424	0.685	NM_014615	KIAA0182	KIAA0182
chr17_-_39700960	0.678	NM_000342	SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr7_+_64136078	0.676		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr10_+_21863272	0.674		MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_60352369	0.673	NM_001126132 NM_001126133 NM_003283	TNNT1	troponin T type 1 (skeletal, slow)
chr11_+_359723	0.672	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr14_-_90352395	0.671
chr7_+_128219307	0.667	NM_022742	CCDC136	coiled-coil domain containing 136
chr19_-_43498386	0.666	NM_001039672 NM_001039673 NM_001145463	YIF1B	Yip1 interacting factor homolog B (S. cerevisiae)
chr1_-_38243716	0.661		FHL3	four and a half LIM domains 3
chr16_+_2807228	0.658		PRSS21	protease, serine, 21 (testisin)
chr19_+_61344501	0.653		ZNF444	zinc finger protein 444
chr10_+_22649977	0.650	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr1_-_21850874	0.649	NM_001145658	RAP1GAP	RAP1 GTPase activating protein
chr12_+_46133	0.647	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr8_-_125252884	0.646		C8orf78	chromosome 8 open reading frame 78
chr17_-_71352090	0.646		UNC13D	unc-13 homolog D (C. elegans)
chr8_-_145671947	0.644		FOXH1	forkhead box H1
chr6_+_143423723	0.639		AIG1	androgen-induced 1
chr8_+_41804946	0.635
chr3_-_187025501	0.634	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr5_+_139008209	0.633	NM_016463	CXXC5	CXXC finger protein 5
chr16_+_387176	0.631	NM_005009	NME4	non-metastatic cells 4, protein expressed in
chr15_-_20637731	0.625	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr11_+_2279932	0.619		TSPAN32	tetraspanin 32
chr16_+_2742606	0.618		SRRM2	serine/arginine repetitive matrix 2
chr10_+_21863579	0.617	NM_001195626	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr20_-_49592444	0.617		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr5_-_138746840	0.617		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr10_+_22650145	0.616		BMI1	BMI1 polycomb ring finger oncogene
chrX_+_128501862	0.616	NM_000276 NM_001587	OCRL	oculocerebrorenal syndrome of Lowe
chr2_+_233443237	0.616	NM_206895	C2orf82	chromosome 2 open reading frame 82
chr3_+_23822353	0.615	NM_003341 NM_182666	UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr4_-_174686918	0.615		HAND2	heart and neural crest derivatives expressed 2
chr2_-_220144427	0.613		OBSL1	obscurin-like 1
chr1_+_110012166	0.611	NM_000848 NM_001142368	GSTM2	glutathione S-transferase mu 2 (muscle)
chr16_+_665680	0.610		RHBDL1	rhomboid, veinlet-like 1 (Drosophila)
chr7_+_100792841	0.608	NM_133457	EMID2	EMI domain containing 2
chr6_-_68655708	0.608

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.89	3.92e-11	GO:0016568	chromatin modification
1.12	2.10e-08	GO:0065007	biological regulation
1.22	3.43e-08	GO:0031323	regulation of cellular metabolic process
1.46	4.59e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.26	8.78e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21	1.40e-07	GO:0080090	regulation of primary metabolic process
1.25	1.91e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.19	4.94e-07	GO:0019222	regulation of metabolic process
1.56	5.01e-07	GO:0051276	chromosome organization
1.62	1.51e-06	GO:0006325	chromatin organization
1.19	1.61e-06	GO:0032502	developmental process
1.12	3.12e-06	GO:0050789	regulation of biological process
1.20	3.34e-06	GO:0007275	multicellular organismal development
1.27	3.48e-06	GO:0048523	negative regulation of cellular process
1.07	3.79e-06	GO:0009987	cellular process
1.26	4.89e-06	GO:0051252	regulation of RNA metabolic process
1.20	6.76e-06	GO:0060255	regulation of macromolecule metabolic process
1.23	1.64e-05	GO:0010468	regulation of gene expression
1.12	1.80e-05	GO:0050794	regulation of cellular process
1.22	2.45e-05	GO:0031326	regulation of cellular biosynthetic process
1.24	2.64e-05	GO:0048519	negative regulation of biological process
1.22	3.27e-05	GO:0009889	regulation of biosynthetic process
1.20	4.20e-05	GO:0048856	anatomical structure development
1.92	4.25e-05	GO:0016569	covalent chromatin modification
1.30	6.28e-05	GO:0007399	nervous system development
1.90	1.24e-04	GO:0016570	histone modification
1.22	1.54e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	1.96e-04	GO:0048731	system development
1.23	3.53e-04	GO:0006355	regulation of transcription, DNA-dependent
1.35	5.65e-04	GO:0009892	negative regulation of metabolic process
1.42	5.78e-04	GO:0009890	negative regulation of biosynthetic process
1.27	5.83e-04	GO:0006996	organelle organization
1.43	6.19e-04	GO:0010628	positive regulation of gene expression
1.21	6.31e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.51	6.35e-04	GO:0019226	transmission of nerve impulse
1.51	6.35e-04	GO:0035637	multicellular organismal signaling
1.43	8.16e-04	GO:0051254	positive regulation of RNA metabolic process
1.36	8.44e-04	GO:0031324	negative regulation of cellular metabolic process
1.42	8.88e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.31	1.16e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.47	1.36e-03	GO:0051253	negative regulation of RNA metabolic process
1.44	1.72e-03	GO:0010629	negative regulation of gene expression
1.52	1.77e-03	GO:0007268	synaptic transmission
1.19	1.79e-03	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47	1.83e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.38	2.54e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	2.70e-03	GO:0009653	anatomical structure morphogenesis
1.11	2.78e-03	GO:0044237	cellular metabolic process
1.23	2.86e-03	GO:0048513	organ development
1.47	2.88e-03	GO:0007417	central nervous system development
1.14	3.39e-03	GO:0044260	cellular macromolecule metabolic process
1.42	3.39e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.42	3.81e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.48	4.03e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.34	4.04e-03	GO:0048468	cell development
1.40	4.24e-03	GO:0045595	regulation of cell differentiation
1.52	4.25e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.21	4.26e-03	GO:0065008	regulation of biological quality
1.28	4.31e-03	GO:0009893	positive regulation of metabolic process
1.18	5.08e-03	GO:0048518	positive regulation of biological process
1.33	5.32e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.41	5.63e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.36	6.09e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.40	6.15e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.41	6.56e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	7.39e-03	GO:0051128	regulation of cellular component organization
1.28	7.79e-03	GO:0031325	positive regulation of cellular metabolic process
1.38	7.84e-03	GO:0030182	neuron differentiation
1.61	9.59e-03	GO:0061061	muscle structure development
1.10	1.27e-02	GO:0044238	primary metabolic process
1.67	1.33e-02	GO:0071375	cellular response to peptide hormone stimulus
1.33	1.36e-02	GO:0048699	generation of neurons
1.51	1.84e-02	GO:0007420	brain development
1.16	1.87e-02	GO:0034641	cellular nitrogen compound metabolic process
1.15	1.94e-02	GO:0016043	cellular component organization
1.39	2.53e-02	GO:0009887	organ morphogenesis
1.31	2.84e-02	GO:0022008	neurogenesis
1.18	2.97e-02	GO:0048522	positive regulation of cellular process
1.11	3.11e-02	GO:0043170	macromolecule metabolic process
1.14	3.25e-02	GO:0071840	cellular component organization or biogenesis
1.17	3.62e-02	GO:0071842	cellular component organization at cellular level
1.09	3.94e-02	GO:0008152	metabolic process
1.35	4.09e-02	GO:0009790	embryo development
1.28	4.63e-02	GO:0007154	cell communication
1.58	4.64e-02	GO:0045596	negative regulation of cell differentiation
1.15	4.78e-02	GO:0006807	nitrogen compound metabolic process
1.48	4.93e-02	GO:0048598	embryonic morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	3.16e-09	GO:0005634	nucleus
1.08	1.65e-08	GO:0044424	intracellular part
1.07	3.45e-08	GO:0005622	intracellular
1.08	2.26e-06	GO:0043226	organelle
1.27	2.43e-06	GO:0031981	nuclear lumen
1.08	3.41e-06	GO:0043229	intracellular organelle
1.25	3.77e-06	GO:0044428	nuclear part
1.23	1.45e-05	GO:0043233	organelle lumen
1.09	1.46e-05	GO:0043227	membrane-bounded organelle
1.09	1.88e-05	GO:0043231	intracellular membrane-bounded organelle
1.22	3.34e-05	GO:0031974	membrane-enclosed lumen
1.22	8.29e-05	GO:0070013	intracellular organelle lumen
1.18	8.46e-05	GO:0043234	protein complex
1.28	3.35e-04	GO:0005654	nucleoplasm
1.36	1.13e-03	GO:0044451	nucleoplasm part
2.04	2.89e-03	GO:0016585	chromatin remodeling complex
1.14	3.92e-03	GO:0032991	macromolecular complex
1.10	9.36e-03	GO:0044422	organelle part
2.54	9.38e-03	GO:0000118	histone deacetylase complex
1.07	1.40e-02	GO:0005737	cytoplasm
3.30	1.51e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.18	1.66e-02	GO:0005829	cytosol
1.09	2.88e-02	GO:0044446	intracellular organelle part
3.54	3.04e-02	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
3.13	3.33e-02	GO:0031519	PcG protein complex
3.71	4.08e-02	GO:0042627	chylomicron
1.99	4.64e-02	GO:0042383	sarcolemma

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.17	1.15e-15	GO:0005515	protein binding
1.56	4.26e-09	GO:0043565	sequence-specific DNA binding
1.43	2.64e-08	GO:0030528	transcription regulator activity
1.07	3.94e-08	GO:0005488	binding
1.37	1.91e-05	GO:0001071	nucleic acid binding transcription factor activity
1.37	1.91e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.62	2.61e-04	GO:0016564	transcription repressor activity
1.74	1.11e-03	GO:0010843	promoter binding
1.16	1.42e-03	GO:0003676	nucleic acid binding
1.19	2.20e-03	GO:0003677	DNA binding
1.72	2.63e-03	GO:0003682	chromatin binding
1.69	2.66e-03	GO:0000975	regulatory region DNA binding
1.69	2.66e-03	GO:0001067	regulatory region nucleic acid binding
1.69	2.66e-03	GO:0044212	transcription regulatory region DNA binding
2.17	4.57e-03	GO:0042393	histone binding
3.15	1.28e-02	GO:0035064	methylated histone residue binding