Motif ID: SMAD1..7,9.p2

Z-value: 1.013


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9



Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_11171213 1.478 NM_001098212
HRH1
histamine receptor H1
chr15_-_81744469 1.396 NM_001717
BNC1
basonuclin 1
chr11_-_65860450 1.322 NM_004292
RIN1
Ras and Rab interactor 1
chr5_-_151046638 1.292 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_151046680 1.217 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_-_6368324 1.082 NM_181864
ACOT7
acyl-CoA thioesterase 7
chr9_-_109291130 1.039 KLF4
Kruppel-like factor 4 (gut)
chr1_+_15145001 1.027 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr8_+_22493928 0.979 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr2_+_102169864 0.890 NM_003854
IL1RL2
interleukin 1 receptor-like 2
chrX_+_102749489 0.874 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr10_+_22765996 0.868 LOC100289455
hypothetical LOC100289455
chr9_-_109291575 0.815 KLF4
Kruppel-like factor 4 (gut)
chr14_+_51850754 0.811 NM_000956
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr13_-_32822759 0.798 STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_-_310925 0.739 IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr6_-_30151526 0.732 NM_170769
NM_025236
RNF39

ring finger protein 39

chr19_+_40299058 0.728 FXYD3
FXYD domain containing ion transport regulator 3
chr11_+_66580884 0.707 RHOD
ras homolog gene family, member D
chr3_+_114414064 0.680 NM_033254
BOC
Boc homolog (mouse)
chr15_+_92575767 0.680 MCTP2
multiple C2 domains, transmembrane 2
chr1_+_31659246 0.677 NM_001199039
NM_018565
SERINC2

serine incorporator 2

chr3_+_185762233 0.674 NM_004443
EPHB3
EPH receptor B3
chr8_+_123863169 0.644 ZHX2
zinc fingers and homeoboxes 2
chr4_+_191242540 0.628 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr11_-_310775 0.624 NM_021034
IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr21_+_38550739 0.613 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_45759691 0.611 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr8_+_123863075 0.602 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr6_-_10520264 0.595 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_79322549 0.593 NM_001010891
NM_001167741
MTX3

metaxin 3

chr17_-_35911340 0.593 NM_032865
TNS4
tensin 4
chr17_-_73867748 0.592 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr16_-_17472238 0.591 NM_022166
XYLT1
xylosyltransferase I
chr11_-_124871258 0.586 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr5_-_58370693 0.571 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr4_+_191229360 0.570 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr19_-_56204615 0.562 NM_012315
KLK9
kallikrein-related peptidase 9
chr4_+_72271218 0.547 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr17_+_12633504 0.540 NM_014859
ARHGAP44
Rho GTPase activating protein 44
chr5_-_16989290 0.536 MYO10
myosin X
chr5_+_149960820 0.532 NM_001166208
SYNPO
synaptopodin
chr17_+_67628749 0.530 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr12_+_56406296 0.526 LOC100130776
hypothetical LOC100130776
chr8_-_10550026 0.525 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr17_-_67628523 0.524 FLJ37644
hypothetical LOC400618
chr1_+_182622850 0.524 C1orf21
chromosome 1 open reading frame 21
chr2_-_218575922 0.520 TNS1
tensin 1
chrX_-_106846253 0.516 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr10_+_135343649 0.516 NM_012147
DUX2
double homeobox 2
chr4_+_191239247 0.513 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_+_2680092 0.513 NM_001141919
NM_001141920
NM_175569
XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chr1_-_197173159 0.513 LOC100131234
familial acute myelogenous leukemia related factor
chr21_+_38550533 0.510 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_134378630 0.508 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr12_-_102968044 0.507 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr5_+_49998677 0.505 PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_+_15964045 0.496 NM_001024216
FBLIM1
filamin binding LIM protein 1
chr15_+_78775008 0.493 FAM108C1
family with sequence similarity 108, member C1
chr10_+_135333667 0.489 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_148621694 0.487 EDNRA
endothelin receptor type A
chr1_-_143750988 0.482 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_50324815 0.478 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chr7_-_41709191 0.470 NM_002192
INHBA
inhibin, beta A
chr3_-_69674412 0.469 FRMD4B
FERM domain containing 4B
chr3_-_45162901 0.458 NM_022842
NM_178181
CDCP1

CUB domain containing protein 1

chr16_+_82959626 0.457 NM_014861
ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
chr20_-_14266200 0.455 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr9_-_103289154 0.453 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr3_+_36396948 0.453 NM_003149
STAC
SH3 and cysteine rich domain
chr12_-_24606616 0.450 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr4_-_119493322 0.447 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr11_+_122258600 0.446 NM_024806
NM_199124
C11orf63

chromosome 11 open reading frame 63

chr8_+_123863224 0.443 ZHX2
zinc fingers and homeoboxes 2
chr19_+_702108 0.442 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr1_+_182622751 0.440 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr17_-_17421050 0.435 PEMT
phosphatidylethanolamine N-methyltransferase
chr9_-_21965131 0.435 NM_000077
NM_001195132
CDKN2A

cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)

chr3_-_45162847 0.432 CDCP1
CUB domain containing protein 1
chr2_-_207738858 0.430 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_-_51200347 0.425 NM_000424
KRT5
keratin 5
chr1_+_182622987 0.419 C1orf21
chromosome 1 open reading frame 21
chr11_-_60475558 0.414 NM_016582
SLC15A3
solute carrier family 15, member 3
chr1_+_44171578 0.412 NM_001136215
NM_057090
NM_057091
ARTN


artemin


chr17_+_56884560 0.410 TBX4
T-box 4
chr1_+_36409277 0.406 MAP7D1
MAP7 domain containing 1
chr12_+_45759634 0.405 FAM113B
family with sequence similarity 113, member B
chr10_+_135330357 0.404 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_148621567 0.403 EDNRA
endothelin receptor type A
chr5_-_146813343 0.403 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr11_+_93394025 0.400 NM_001098672
HEPHL1
hephaestin-like 1
chr8_-_145085616 0.394 NM_201384
PLEC
plectin
chr2_+_17923404 0.393 NM_002252
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr1_-_26553168 0.393 NM_001039775
AIM1L
absent in melanoma 1-like
chrX_+_110226030 0.390 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr18_+_40513889 0.390 NM_001130110
SETBP1
SET binding protein 1
chr12_-_102967828 0.390 GLT8D2
glycosyltransferase 8 domain containing 2
chr15_+_97010219 0.388 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr12_+_2032964 0.388 CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr9_-_21964825 0.387 NM_058197
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr3_-_45162783 0.386


chr13_-_39075304 0.382 LHFP
lipoma HMGIC fusion partner
chr4_+_191232653 0.381 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr1_-_10779291 0.372 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr17_+_74531873 0.372 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_72795567 0.371 NM_001113492
SEPT9
septin 9
chr1_-_93919789 0.371 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr19_-_50977586 0.371 DMPK
dystrophia myotonica-protein kinase
chr9_+_36026900 0.370 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr11_-_110888273 0.370 NM_017589
BTG4
B-cell translocation gene 4
chr8_-_145122884 0.370 NM_000445
PLEC
plectin
chr15_-_68971665 0.369 NM_020147
THAP10
THAP domain containing 10
chr9_+_90339835 0.366 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr14_+_64240902 0.366 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_+_39918302 0.366 NM_001114633
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr1_-_115682374 0.365 NM_002506
NGF
nerve growth factor (beta polypeptide)
chrX_-_62891730 0.363 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chrX_+_149280486 0.363 MAMLD1
mastermind-like domain containing 1
chr3_-_150858274 0.362 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr16_+_22732982 0.361 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr14_-_89155078 0.361 NM_001085471
FOXN3
forkhead box N3
chr6_+_106640881 0.359 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr17_-_68100537 0.358 LOC100499467
hypothetical LOC100499467
chr1_+_182622809 0.357 C1orf21
chromosome 1 open reading frame 21
chr22_+_44828338 0.357


chr8_+_128817658 0.355 MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chr7_-_27108826 0.354 NM_006735
HOXA2
homeobox A2
chr11_+_66580861 0.352 NM_014578
RHOD
ras homolog gene family, member D
chr16_-_73830025 0.352 BCAR1
breast cancer anti-estrogen resistance 1
chr17_+_7199178 0.350 NM_198154
TMEM95
transmembrane protein 95
chr17_-_72093529 0.348 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr6_-_32929570 0.347 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr15_-_40236061 0.346 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr12_-_113328271 0.345 NM_181486
TBX5
T-box 5
chr17_-_72093739 0.344 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr22_+_38720881 0.341 NM_138435
FAM83F
family with sequence similarity 83, member F
chr14_+_92330383 0.341 NM_005113
GOLGA5
golgin A5
chr9_-_90456824 0.336 NM_001100111
LOC286238
hypothetical protein LOC286238
chrX_+_106956115 0.336 MID2
midline 2
chr4_+_148621518 0.335 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr16_+_55580910 0.335 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr8_-_70909754 0.335 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr7_+_1543644 0.335 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_199884152 0.332 NAV1
neuron navigator 1
chr12_+_55896844 0.332 NM_007224
NXPH4
neurexophilin 4
chrX_-_106846684 0.332 TSC22D3
TSC22 domain family, member 3
chr15_-_38420414 0.332 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr1_+_178466064 0.332 NM_033343
LHX4
LIM homeobox 4
chr17_-_72093476 0.331 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr17_+_74531820 0.330 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr8_-_57395207 0.330 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr9_-_37566248 0.329 NM_012166
FBXO10
F-box protein 10
chr8_-_120033240 0.329 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr7_-_141293185 0.329 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr6_+_139055244 0.329 FLJ46906
hypothetical LOC441172
chr2_+_30307900 0.329 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr19_-_60573552 0.328 NM_000641
IL11
interleukin 11
chr17_-_7996409 0.327 NM_002616
PER1
period homolog 1 (Drosophila)
chrX_-_62891667 0.325 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_+_129823667 0.323 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr15_+_75074793 0.322 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chrX_-_62891066 0.322 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr10_+_112247614 0.321 NM_004419
DUSP5
dual specificity phosphatase 5
chr8_-_72918697 0.320 MSC
musculin
chr15_+_75074483 0.317 NM_003978
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_+_16901455 0.316 NM_001144382
PLCL2
phospholipase C-like 2
chr10_-_98021144 0.316 NM_001114094
NM_013314
BLNK

B-cell linker

chr15_-_58706934 0.313 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr16_+_2071631 0.313 TSC2
tuberous sclerosis 2
chr4_+_191226073 0.310 NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr4_-_8211335 0.310 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr19_-_50977592 0.309 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr14_+_64240996 0.309 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr20_+_48241334 0.308 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr4_-_1192749 0.305 NM_001199021
LOC100130872
SPON2
hypothetical LOC100130872
spondin 2, extracellular matrix protein
chr11_-_119104463 0.305 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr6_-_128883125 0.303 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_-_158091760 0.303 NM_001134233
C1orf204
chromosome 1 open reading frame 204
chr5_+_72452131 0.302 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr3_+_89239363 0.301 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr21_+_33560540 0.301 NM_000628
IL10RB
interleukin 10 receptor, beta
chr10_-_73203202 0.299 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr18_-_45630154 0.298 MYO5B
myosin VB
chr14_-_49543987 0.297 NM_001012706
C14orf182
chromosome 14 open reading frame 182
chr1_+_204049053 0.296


chr6_-_32929390 0.295 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_88718167 0.293 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr2_+_17585462 0.292 VSNL1
visinin-like 1
chr14_+_20608179 0.292 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr7_+_75977680 0.291 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr9_-_112840801 0.290 LPAR1
lysophosphatidic acid receptor 1
chr1_-_32036858 0.290 SPOCD1
SPOC domain containing 1
chr6_-_25019173 0.288 NM_014722
FAM65B
family with sequence similarity 65, member B
chr22_-_41583248 0.288 NM_001142293
NM_014570
ARFGAP3

ADP-ribosylation factor GTPase activating protein 3

chr3_+_11153778 0.288 NM_001098213
HRH1
histamine receptor H1
chr14_+_63750611 0.287 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chrX_+_48915127 0.287 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr22_+_29848923 0.287 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_-_39180036 0.287 NM_017821
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr22_+_31527678 0.287 TIMP3
TIMP metallopeptidase inhibitor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 2.38e-06 GO:0007165 signal transduction
1.77 1.91e-05 GO:0048812 neuron projection morphogenesis
1.23 1.94e-05 GO:0023052 signaling
1.79 2.05e-05 GO:0007409 axonogenesis
1.72 3.17e-05 GO:0031175 neuron projection development
1.77 3.20e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.41 3.59e-05 GO:0035556 intracellular signal transduction
1.70 4.06e-05 GO:0032990 cell part morphogenesis
1.70 4.91e-05 GO:0048858 cell projection morphogenesis
1.61 6.89e-05 GO:0030030 cell projection organization
1.62 1.90e-04 GO:0048666 neuron development
1.82 2.72e-04 GO:0007411 axon guidance
1.64 3.52e-04 GO:0006935 chemotaxis
1.64 3.52e-04 GO:0042330 taxis
1.36 3.54e-04 GO:0009653 anatomical structure morphogenesis
1.25 4.43e-04 GO:0048731 system development
1.47 4.56e-04 GO:0022008 neurogenesis
1.22 7.88e-04 GO:0048856 anatomical structure development
1.64 8.29e-04 GO:0000904 cell morphogenesis involved in differentiation
1.53 1.01e-03 GO:0030182 neuron differentiation
1.37 1.05e-03 GO:0051239 regulation of multicellular organismal process
1.46 1.35e-03 GO:0048699 generation of neurons
1.56 1.70e-03 GO:0000902 cell morphogenesis
1.54 1.86e-03 GO:0032989 cellular component morphogenesis
1.28 2.21e-03 GO:0048869 cellular developmental process
1.11 2.98e-03 GO:0065007 biological regulation
1.28 3.10e-03 GO:0030154 cell differentiation
1.12 3.62e-03 GO:0050794 regulation of cellular process
1.25 3.88e-03 GO:0048519 negative regulation of biological process
1.33 4.83e-03 GO:0007399 nervous system development
1.42 6.29e-03 GO:0048468 cell development
1.17 6.44e-03 GO:0051716 cellular response to stimulus
1.19 6.57e-03 GO:0007275 multicellular organismal development
1.40 7.06e-03 GO:0009605 response to external stimulus
1.43 8.48e-03 GO:0040011 locomotion
1.25 1.13e-02 GO:0048523 negative regulation of cellular process
1.11 1.51e-02 GO:0050789 regulation of biological process
2.20 2.27e-02 GO:0035023 regulation of Rho protein signal transduction
6.35 2.33e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
3.23 2.70e-02 GO:0021675 nerve development
1.52 3.67e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.42 4.13e-02 GO:2000026 regulation of multicellular organismal development
1.39 4.40e-02 GO:0009888 tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.29 1.67e-06 GO:0070161 anchoring junction
2.29 9.02e-06 GO:0005912 adherens junction
2.35 8.84e-04 GO:0005925 focal adhesion
2.30 9.76e-04 GO:0005924 cell-substrate adherens junction
2.22 2.45e-03 GO:0030055 cell-substrate junction
1.15 8.81e-03 GO:0071944 cell periphery
1.15 1.08e-02 GO:0005886 plasma membrane
1.26 2.20e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.57 4.30e-04 GO:0008092 cytoskeletal protein binding
1.50 2.81e-02 GO:0030695 GTPase regulator activity
1.59 5.00e-02 GO:0003779 actin binding