Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.661


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZHX1chr8_-_1243556700.552.6e-02Click!
IRX5chr16_+_535226110.514.6e-02Click!
SIX2chr2_-_450900250.381.5e-01Click!
ZHX3chr20_-_39379533-0.224.1e-01Click!
ZHX2chr8_+_124032830-0.204.5e-01Click!
IRX4chr5_-_19357640.194.8e-01Click!
ADNPchr20_-_489808580.116.9e-01Click!
SIX5chr19_-_50964336-0.058.6e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_556968 2.545


chr9_-_205892 1.271 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr18_+_27210737 1.213 NM_001134453
NM_177986
DSG4

desmoglein 4

chr2_+_166137091 1.196 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr21_-_14840506 1.196 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_155818728 1.139 NM_015718
NOX3
NADPH oxidase 3
chr6_+_49575629 1.133 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr9_-_99740243 1.100 NM_197978
HEMGN
hemogen
chr17_-_64752550 1.044 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr17_-_36376663 1.035 NM_213656
KRT39
keratin 39
chr3_-_166278969 1.029 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr3_+_174598937 1.014 NM_014932
NLGN1
neuroligin 1
chr1_-_156923111 0.993 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_113842284 0.986 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr6_-_49820030 0.982 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr4_+_74520796 0.976 NM_001134
AFP
alpha-fetoprotein
chr17_-_10265991 0.961 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr14_+_67238355 0.960 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr7_-_91632525 0.959 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chr2_+_200031333 0.953


chr1_+_86707113 0.952 NM_001285
CLCA1
chloride channel accessory 1
chr2_+_102401580 0.907 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr2_-_131073329 0.903 NM_032545
NM_001079530
CFC1
CFC1B
cripto, FRL-1, cryptic family 1
cripto, FRL-1, cryptic family 1B
chr10_-_21847126 0.902


chr12_+_79362256 0.891 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr1_-_155936904 0.885 NM_052939
FCRL3
Fc receptor-like 3
chr4_-_163304567 0.877 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr15_+_46285789 0.875 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chrX_-_18600108 0.875 NM_000330
RS1
retinoschisin 1
chr16_-_73012740 0.872 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr15_-_96875133 0.861 NM_182562
FAM169B
family with sequence similarity 169, member B
chrX_+_99726445 0.858 NM_022144
TNMD
tenomodulin
chr17_+_25292748 0.841 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr11_-_16454493 0.816 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr10_+_44726635 0.802 NM_001123376
TMEM72
transmembrane protein 72
chr2_+_169465995 0.775 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr8_-_72431274 0.772 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr16_+_20370359 0.772 NM_001010845
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr6_-_25982418 0.761 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr6_+_12825818 0.746 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr7_-_25234582 0.741 NM_022150
NPVF
neuropeptide VF precursor
chr2_+_161981046 0.737 TBR1
T-box, brain, 1
chr6_-_89984214 0.736 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr3_-_197726587 0.729 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr5_+_139485703 0.728 NM_001007189
C5orf53
chromosome 5 open reading frame 53
chr7_+_106897737 0.717 NM_005295
GPR22
G protein-coupled receptor 22
chr9_+_101628829 0.713 NM_173200
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr1_+_557269 0.710


chr4_-_185376012 0.699 NM_153343
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr13_+_112349358 0.679 NM_207440
C13orf35
chromosome 13 open reading frame 35
chr12_-_16321885 0.667 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr3_-_184756101 0.664 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_+_158559936 0.663 NM_001135098
UPP2
uridine phosphorylase 2
chr5_-_22889192 0.661 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr6_-_29163027 0.648 NM_001005226
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr6_-_33016561 0.643 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_-_69033515 0.636 NM_182536
GKN2
gastrokine 2
chr11_-_62668268 0.636 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr2_-_144994038 0.633 ZEB2
zinc finger E-box binding homeobox 2
chr2_+_157822355 0.620 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_5279750 0.618 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr6_-_50097606 0.617 NM_001037497
NM_001037728
DEFB110

defensin, beta 110 locus

chr6_+_29249289 0.616 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr3_+_153074118 0.612 NM_033050
SUCNR1
succinate receptor 1
chr18_+_50409387 0.612 NM_173629
C18orf26
chromosome 18 open reading frame 26
chr10_-_17211795 0.608 NM_001081
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr6_+_50894397 0.605 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr20_-_7869068 0.597 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr1_+_67404756 0.597 NM_144701
IL23R
interleukin 23 receptor
chr2_+_204509698 0.597 NM_012092
ICOS
inducible T-cell co-stimulator
chr14_-_20098929 0.590 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr15_+_48434397 0.589 LOC100129387
hypothetical LOC100129387
chr2_+_166034402 0.588 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr7_-_15568099 0.584 NM_001004320
AGMO
alkylglycerol monooxygenase
chr17_+_4638966 0.582 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr5_-_131907071 0.581 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr8_-_102872354 0.579 NCALD
neurocalcin delta
chr14_-_91268136 0.574 NM_024764
CATSPERB
cation channel, sperm-associated, beta
chr11_-_55661769 0.570 NM_001004064
OR8J3
olfactory receptor, family 8, subfamily J, member 3
chrX_-_55074125 0.569 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr1_-_114215768 0.566 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr1_+_152560179 0.565 NM_080429
AQP10
aquaporin 10
chr7_+_29840865 0.550 NM_001080529
WIPF3
WAS/WASL interacting protein family, member 3
chr5_-_22889487 0.545 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr9_-_94226380 0.544 NM_005014
OMD
osteomodulin
chr11_+_59564323 0.544 NM_173801
PLAC1L
placenta-specific 1-like
chr9_+_134843918 0.537 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr1_+_195503956 0.537 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr11_-_123685871 0.534 NM_001002917
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr16_+_68765428 0.531 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr2_+_161981138 0.530 TBR1
T-box, brain, 1
chr5_+_147672181 0.527 NM_032566
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr1_-_115039614 0.522 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr4_-_64957595 0.519 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr2_-_87102453 0.513 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr5_-_134290789 0.510


chr5_-_1935764 0.500 NM_016358
IRX4
iroquois homeobox 4
chr2_+_176677479 0.496


chr3_-_69254226 0.495 NM_198271
LMOD3
leiomodin 3 (fetal)
chr17_-_25685175 0.495 NM_206832
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr5_+_60969392 0.494 NM_173667
FLJ37543
hypothetical protein FLJ37543
chr4_-_69116839 0.493 NM_001077
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr6_-_27988152 0.491 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr8_-_108579270 0.484 NM_001146
ANGPT1
angiopoietin 1
chr17_-_64568641 0.482 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_-_57209319 0.482 NM_003865
HESX1
HESX homeobox 1
chr2_-_208763017 0.480 NM_001099334
C2orf80
chromosome 2 open reading frame 80
chr5_+_152850276 0.479 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr2_+_161980865 0.475 NM_006593
TBR1
T-box, brain, 1
chr5_-_88235624 0.475 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_+_123600553 0.474 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr5_-_27074407 0.473 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr21_-_30460841 0.472 NM_012131
CLDN17
claudin 17
chr2_+_220087135 0.472 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr4_+_74825138 0.470 NM_000584
IL8
interleukin 8
chr1_-_246804680 0.470 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr3_-_147696411 0.469 NM_020359
PLSCR2
phospholipid scramblase 2
chr22_-_15682555 0.467 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr12_+_8557402 0.467 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr6_+_105511615 0.461 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chrX_+_90977115 0.461 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr20_-_604822 0.460 NM_033129
SCRT2
scratch homolog 2, zinc finger protein (Drosophila)
chr13_-_69580459 0.459 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr21_-_38955487 0.457 NM_001136154
NM_004449
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr10_+_68355797 0.456 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr12_+_56802 0.455 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr22_+_21065134 0.455 LOC100290481
immunoglobulin lambda light chain-like
chr11_+_113280727 0.450 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr5_-_95774444 0.446 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr16_-_20495126 0.445 NM_001105069
NM_182617
ACSM2B

acyl-CoA synthetase medium-chain family member 2B

chr4_+_88748704 0.442 NM_014208
DSPP
dentin sialophosphoprotein
chr13_-_34948758 0.441 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr19_+_15699833 0.440 NM_013939
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr6_+_29534109 0.440 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr3_-_36756355 0.439 NM_033403
DCLK3
doublecortin-like kinase 3
chr6_+_25862905 0.438 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr20_+_186376 0.436 NM_207469
DEFB132
defensin, beta 132
chr2_-_99238001 0.435 NM_175735
LYG2
lysozyme G-like 2
chr4_+_96980261 0.434 NM_005390
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2
chr4_+_78651929 0.432 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr2_+_185171337 0.431 NM_194250
ZNF804A
zinc finger protein 804A
chr17_-_30909219 0.430 NM_001129820
SLFN14
schlafen family member 14
chr6_+_112775224 0.429 NM_001013734
RFPL4B
ret finger protein-like 4B
chr1_-_120189301 0.429 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr1_+_100776280 0.428 NM_022049
GPR88
G protein-coupled receptor 88
chr1_+_226712430 0.426 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_-_245763763 0.425 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr1_+_196153122 0.423 NM_020204
LHX9
LIM homeobox 9
chr6_-_133008834 0.423 NM_138327
TAAR1
trace amine associated receptor 1
chr2_+_185171480 0.421 ZNF804A
zinc finger protein 804A
chr19_+_53450743 0.420


chr10_-_6144119 0.416 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr1_-_108588186 0.414 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chrX_+_37524250 0.414 CYBB
cytochrome b-245, beta polypeptide
chrX_-_133620103 0.412 NM_021796
PLAC1
placenta-specific 1
chr17_-_44006808 0.408 NM_002146
HOXB3
homeobox B3
chr1_-_191422346 0.406 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr20_+_30019465 0.405 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr1_-_214663360 0.404 NM_007123
NM_206933
USH2A

Usher syndrome 2A (autosomal recessive, mild)

chr3_+_35697432 0.401 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chrX_-_106033202 0.400 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr2_+_225973845 0.398 NM_020864
KIAA1486
KIAA1486
chr4_+_71142893 0.396 NM_005212
CSN3
casein kappa
chr6_+_54281161 0.394 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr4_-_44348414 0.394 NM_182592
YIPF7
Yip1 domain family, member 7
chr1_+_196874839 0.393 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_+_34599163 0.392 NM_012153
EHF
ets homologous factor
chr3_-_196792059 0.391 APOD
apolipoprotein D
chr1_+_115373937 0.386 NM_000549
TSHB
thyroid stimulating hormone, beta
chr12_+_52680143 0.385 NM_006897
HOXC9
homeobox C9
chr11_+_64114857 0.383 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr2_+_158666627 0.383 NM_173355
UPP2
uridine phosphorylase 2
chr2_-_200030412 0.382 SATB2
SATB homeobox 2
chr5_+_169713458 0.381 NM_001034838
KCNIP1
Kv channel interacting protein 1
chr1_+_196874759 0.376 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr4_-_176970407 0.375 GPM6A
glycoprotein M6A
chr6_-_2696152 0.375 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr1_-_224195495 0.373 NM_001172425
NM_003240
LEFTY2

left-right determination factor 2

chr12_-_10497195 0.371 NM_002259
NM_007328
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr18_-_13905534 0.371 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr19_-_60941551 0.370 NM_176820
NLRP9
NLR family, pyrin domain containing 9
chr15_+_56217686 0.370 NM_020980
AQP9
aquaporin 9
chr17_-_70367479 0.369 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr15_-_48434340 0.369 FLJ10038
hypothetical protein FLJ10038
chr4_+_46728051 0.367 NM_000812
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr1_+_108794426 0.364 NM_001143987
NM_001143988
NBPF4
NBPF6

neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6

chr6_+_154402135 0.363 NM_000914
NM_001008503
NM_001008504
NM_001008505
NM_001145282
NM_001145283
NM_001145285
NM_001145286
NM_001145284
OPRM1








opioid receptor, mu 1








chr7_-_83116414 0.360 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr5_+_140583098 0.360 NM_018934
PCDHB14
protocadherin beta 14
chr3_+_46370228 0.357 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr6_-_2580296 0.357 NM_152554
C6orf195
chromosome 6 open reading frame 195
chrX_-_65176564 0.357 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr11_-_89181390 0.355 NM_020358
TRIM49
tripartite motif containing 49
chr7_+_129693938 0.355 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chrX_-_142551587 0.352 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr20_+_58064360 0.352 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr1_+_109057078 0.351 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr6_+_55300225 0.351 NM_207410
GFRAL
GDNF family receptor alpha like
chr18_+_27152049 0.349 NM_001942
DSG1
desmoglein 1
chr2_-_113526910 0.349 NM_014438
NM_173178
IL1F8

interleukin 1 family, member 8 (eta)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.73 4.27e-32 GO:0007600 sensory perception
3.46 1.96e-29 GO:0007608 sensory perception of smell
3.29 3.34e-29 GO:0007606 sensory perception of chemical stimulus
2.17 5.44e-27 GO:0050877 neurological system process
1.96 7.30e-24 GO:0003008 system process
1.39 1.51e-17 GO:0032501 multicellular organismal process
1.25 7.31e-09 GO:0050896 response to stimulus
1.56 4.16e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.42 2.29e-15 GO:0005886 plasma membrane
1.41 4.28e-15 GO:0071944 cell periphery
1.31 9.99e-13 GO:0031224 intrinsic to membrane
1.31 4.73e-12 GO:0016021 integral to membrane
1.24 8.86e-10 GO:0044425 membrane part
1.50 5.55e-09 GO:0005576 extracellular region
1.53 4.24e-04 GO:0044421 extracellular region part
1.14 5.57e-04 GO:0016020 membrane
1.57 1.56e-03 GO:0005615 extracellular space
1.29 9.85e-03 GO:0044459 plasma membrane part
1.97 3.68e-02 GO:0045177 apical part of cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.60 2.00e-31 GO:0004984 olfactory receptor activity
2.17 3.24e-26 GO:0004888 transmembrane receptor activity
2.48 1.61e-25 GO:0004930 G-protein coupled receptor activity
1.94 5.07e-24 GO:0004872 receptor activity
1.72 1.80e-18 GO:0004871 signal transducer activity
1.72 1.80e-18 GO:0060089 molecular transducer activity
5.78 3.96e-03 GO:0004890 GABA-A receptor activity
4.99 1.70e-02 GO:0016917 GABA receptor activity
4.36 2.47e-02 GO:0015020 glucuronosyltransferase activity
2.92 2.50e-02 GO:0005254 chloride channel activity
2.74 3.65e-02 GO:0005253 anion channel activity