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Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.661

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_556968	2.545
chr9_-_205892	1.271	NM_152569	C9orf66	chromosome 9 open reading frame 66
chr18_+_27210737	1.213	NM_001134453 NM_177986	DSG4	desmoglein 4
chr2_+_166137091	1.196	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr21_-_14840506	1.196	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_155818728	1.139	NM_015718	NOX3	NADPH oxidase 3
chr6_+_49575629	1.133	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr9_-_99740243	1.100	NM_197978	HEMGN	hemogen
chr17_-_64752550	1.044	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr17_-_36376663	1.035	NM_213656	KRT39	keratin 39
chr3_-_166278969	1.029	NM_001041	SI	sucrase-isomaltase (alpha-glucosidase)
chr3_+_174598937	1.014	NM_014932	NLGN1	neuroligin 1
chr1_-_156923111	0.993	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_113842284	0.986	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr6_-_49820030	0.982	NM_001190986 NM_006061	CRISP3	cysteine-rich secretory protein 3
chr4_+_74520796	0.976	NM_001134	AFP	alpha-fetoprotein
chr17_-_10265991	0.961	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr14_+_67238355	0.960	NM_152443	RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr7_-_91632525	0.959	NM_001161528	LOC401387	leucine-rich repeat and death domain-containing protein
chr2_+_200031333	0.953
chr1_+_86707113	0.952	NM_001285	CLCA1	chloride channel accessory 1
chr2_+_102401580	0.907	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr2_-_131073329	0.903	NM_032545 NM_001079530	CFC1 CFC1B	cripto, FRL-1, cryptic family 1 cripto, FRL-1, cryptic family 1B
chr10_-_21847126	0.902
chr12_+_79362256	0.891	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr1_-_155936904	0.885	NM_052939	FCRL3	Fc receptor-like 3
chr4_-_163304567	0.877	NM_001128427 NM_001128428 NM_020116	FSTL5	follistatin-like 5
chr15_+_46285789	0.875	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chrX_-_18600108	0.875	NM_000330	RS1	retinoschisin 1
chr16_-_73012740	0.872	NM_001011880	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr15_-_96875133	0.861	NM_182562	FAM169B	family with sequence similarity 169, member B
chrX_+_99726445	0.858	NM_022144	TNMD	tenomodulin
chr17_+_25292748	0.841	NM_198529	EFCAB5	EF-hand calcium binding domain 5
chr11_-_16454493	0.816	NM_033326	SOX6	SRY (sex determining region Y)-box 6
chr10_+_44726635	0.802	NM_001123376	TMEM72	transmembrane protein 72
chr2_+_169465995	0.775	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr8_-_72431274	0.772	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr16_+_20370359	0.772	NM_001010845	ACSM2A	acyl-CoA synthetase medium-chain family member 2A
chr6_-_25982418	0.761	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr6_+_12825818	0.746	NM_030948	PHACTR1	phosphatase and actin regulator 1
chr7_-_25234582	0.741	NM_022150	NPVF	neuropeptide VF precursor
chr2_+_161981046	0.737		TBR1	T-box, brain, 1
chr6_-_89984214	0.736	NM_002042	GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1
chr3_-_197726587	0.729	NM_001077657	C3orf43	chromosome 3 open reading frame 43
chr5_+_139485703	0.728	NM_001007189	C5orf53	chromosome 5 open reading frame 53
chr7_+_106897737	0.717	NM_005295	GPR22	G protein-coupled receptor 22
chr9_+_101628829	0.713	NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr1_+_557269	0.710
chr4_-_185376012	0.699	NM_153343	ENPP6	ectonucleotide pyrophosphatase/phosphodiesterase 6
chr13_+_112349358	0.679	NM_207440	C13orf35	chromosome 13 open reading frame 35
chr12_-_16321885	0.667	NM_001170798	SLC15A5	solute carrier family 15, member 5
chr3_-_184756101	0.664	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr2_+_158559936	0.663	NM_001135098	UPP2	uridine phosphorylase 2
chr5_-_22889192	0.661		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr6_-_29163027	0.648	NM_001005226	OR2B3	olfactory receptor, family 2, subfamily B, member 3
chr6_-_33016561	0.643	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr2_-_69033515	0.636	NM_182536	GKN2	gastrokine 2
chr11_-_62668268	0.636	NM_001136506	SLC22A24	solute carrier family 22, member 24
chr2_-_144994038	0.633		ZEB2	zinc finger E-box binding homeobox 2
chr2_+_157822355	0.620	NM_014568	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_5279750	0.618	NM_033179	OR51B4	olfactory receptor, family 51, subfamily B, member 4
chr6_-_50097606	0.617	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chr6_+_29249289	0.616	NM_030905	OR2J2	olfactory receptor, family 2, subfamily J, member 2
chr3_+_153074118	0.612	NM_033050	SUCNR1	succinate receptor 1
chr18_+_50409387	0.612	NM_173629	C18orf26	chromosome 18 open reading frame 26
chr10_-_17211795	0.608	NM_001081	CUBN	cubilin (intrinsic factor-cobalamin receptor)
chr6_+_50894397	0.605	NM_003221	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr20_-_7869068	0.597	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr1_+_67404756	0.597	NM_144701	IL23R	interleukin 23 receptor
chr2_+_204509698	0.597	NM_012092	ICOS	inducible T-cell co-stimulator
chr14_-_20098929	0.590	NM_001001673 NM_001110356 NM_001110357 NM_001110358 NM_001110359 NM_001110360 NM_001110361	RNASE9	ribonuclease, RNase A family, 9 (non-active)
chr15_+_48434397	0.589		LOC100129387	hypothetical LOC100129387
chr2_+_166034402	0.588	NM_001172173	CSRNP3	cysteine-serine-rich nuclear protein 3
chr7_-_15568099	0.584	NM_001004320	AGMO	alkylglycerol monooxygenase
chr17_+_4638966	0.582	NM_001014985	GLTPD2	glycolipid transfer protein domain containing 2
chr5_-_131907071	0.581	NM_000879	IL5	interleukin 5 (colony-stimulating factor, eosinophil)
chr8_-_102872354	0.579		NCALD	neurocalcin delta
chr14_-_91268136	0.574	NM_024764	CATSPERB	cation channel, sperm-associated, beta
chr11_-_55661769	0.570	NM_001004064	OR8J3	olfactory receptor, family 8, subfamily J, member 3
chrX_-_55074125	0.569	NM_000032 NM_001037967 NM_001037968	ALAS2	aminolevulinate, delta-, synthase 2
chr1_-_114215768	0.566	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr1_+_152560179	0.565	NM_080429	AQP10	aquaporin 10
chr7_+_29840865	0.550	NM_001080529	WIPF3	WAS/WASL interacting protein family, member 3
chr5_-_22889487	0.545	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr9_-_94226380	0.544	NM_005014	OMD	osteomodulin
chr11_+_59564323	0.544	NM_173801	PLAC1L	placenta-specific 1-like
chr9_+_134843918	0.537	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr1_+_195503956	0.537	NM_001193640 NM_201253	CRB1	crumbs homolog 1 (Drosophila)
chr11_-_123685871	0.534	NM_001002917	OR8D1	olfactory receptor, family 8, subfamily D, member 1
chr16_+_68765428	0.531	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr2_+_161981138	0.530		TBR1	T-box, brain, 1
chr5_+_147672181	0.527	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr1_-_115039614	0.522	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr4_-_64957595	0.519	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr2_-_87102453	0.513	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr5_-_134290789	0.510
chr5_-_1935764	0.500	NM_016358	IRX4	iroquois homeobox 4
chr2_+_176677479	0.496
chr3_-_69254226	0.495	NM_198271	LMOD3	leiomodin 3 (fetal)
chr17_-_25685175	0.495	NM_206832	TMIGD1	transmembrane and immunoglobulin domain containing 1
chr5_+_60969392	0.494	NM_173667	FLJ37543	hypothetical protein FLJ37543
chr4_-_69116839	0.493	NM_001077	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17
chr6_-_27988152	0.491	NM_033057	OR2B2	olfactory receptor, family 2, subfamily B, member 2
chr8_-_108579270	0.484	NM_001146	ANGPT1	angiopoietin 1
chr17_-_64568641	0.482	NM_080283	ABCA9	ATP-binding cassette, sub-family A (ABC1), member 9
chr3_-_57209319	0.482	NM_003865	HESX1	HESX homeobox 1
chr2_-_208763017	0.480	NM_001099334	C2orf80	chromosome 2 open reading frame 80
chr5_+_152850276	0.479	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr2_+_161980865	0.475	NM_006593	TBR1	T-box, brain, 1
chr5_-_88235624	0.475	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr11_+_123600553	0.474	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr5_-_27074407	0.473	NM_016279	CDH9	cadherin 9, type 2 (T1-cadherin)
chr21_-_30460841	0.472	NM_012131	CLDN17	claudin 17
chr2_+_220087135	0.472	NM_018674 NM_182847	ACCN4	amiloride-sensitive cation channel 4, pituitary
chr4_+_74825138	0.470	NM_000584	IL8	interleukin 8
chr1_-_246804680	0.470	NM_001001821	OR2T34	olfactory receptor, family 2, subfamily T, member 34
chr3_-_147696411	0.469	NM_020359	PLSCR2	phospholipid scramblase 2
chr22_-_15682555	0.467	NM_175878	XKR3	XK, Kell blood group complex subunit-related family, member 3
chr12_+_8557402	0.467	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr6_+_105511615	0.461	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chrX_+_90977115	0.461	NM_001168360 NM_001168361 NM_001168362 NM_001168363	PCDH11X	protocadherin 11 X-linked
chr20_-_604822	0.460	NM_033129	SCRT2	scratch homolog 2, zinc finger protein (Drosophila)
chr13_-_69580459	0.459	NM_020866	KLHL1	kelch-like 1 (Drosophila)
chr21_-_38955487	0.457	NM_001136154 NM_004449	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr10_+_68355797	0.456	NM_178011	LRRTM3	leucine rich repeat transmembrane neuronal 3
chr12_+_56802	0.455	NM_015232	IQSEC3	IQ motif and Sec7 domain 3
chr22_+_21065134	0.455		LOC100290481	immunoglobulin lambda light chain-like
chr11_+_113280727	0.450	NM_006028	HTR3B	5-hydroxytryptamine (serotonin) receptor 3B
chr5_-_95774444	0.446	NM_001177876	PCSK1	proprotein convertase subtilisin/kexin type 1
chr16_-_20495126	0.445	NM_001105069 NM_182617	ACSM2B	acyl-CoA synthetase medium-chain family member 2B
chr4_+_88748704	0.442	NM_014208	DSPP	dentin sialophosphoprotein
chr13_-_34948758	0.441	NM_005584	MAB21L1	mab-21-like 1 (C. elegans)
chr19_+_15699833	0.440	NM_013939	OR10H2	olfactory receptor, family 10, subfamily H, member 2
chr6_+_29534109	0.440	NM_030883	OR2H1	olfactory receptor, family 2, subfamily H, member 1
chr3_-_36756355	0.439	NM_033403	DCLK3	doublecortin-like kinase 3
chr6_+_25862905	0.438	NM_005495	SLC17A4	solute carrier family 17 (sodium phosphate), member 4
chr20_+_186376	0.436	NM_207469	DEFB132	defensin, beta 132
chr2_-_99238001	0.435	NM_175735	LYG2	lysozyme G-like 2
chr4_+_96980261	0.434	NM_005390	PDHA2	pyruvate dehydrogenase (lipoamide) alpha 2
chr4_+_78651929	0.432	NM_006419	CXCL13	chemokine (C-X-C motif) ligand 13
chr2_+_185171337	0.431	NM_194250	ZNF804A	zinc finger protein 804A
chr17_-_30909219	0.430	NM_001129820	SLFN14	schlafen family member 14
chr6_+_112775224	0.429	NM_001013734	RFPL4B	ret finger protein-like 4B
chr1_-_120189301	0.429	NM_001047980	NBPF7	neuroblastoma breakpoint family, member 7
chr1_+_100776280	0.428	NM_022049	GPR88	G protein-coupled receptor 88
chr1_+_226712430	0.426	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr1_-_245763763	0.425	NM_198074	OR2C3	olfactory receptor, family 2, subfamily C, member 3
chr1_+_196153122	0.423	NM_020204	LHX9	LIM homeobox 9
chr6_-_133008834	0.423	NM_138327	TAAR1	trace amine associated receptor 1
chr2_+_185171480	0.421		ZNF804A	zinc finger protein 804A
chr19_+_53450743	0.420
chr10_-_6144119	0.416	NM_000417	IL2RA	interleukin 2 receptor, alpha
chr1_-_108588186	0.414	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chrX_+_37524250	0.414		CYBB	cytochrome b-245, beta polypeptide
chrX_-_133620103	0.412	NM_021796	PLAC1	placenta-specific 1
chr17_-_44006808	0.408	NM_002146	HOXB3	homeobox B3
chr1_-_191422346	0.406	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr20_+_30019465	0.405	NM_001011718	XKR7	XK, Kell blood group complex subunit-related family, member 7
chr1_-_214663360	0.404	NM_007123 NM_206933	USH2A	Usher syndrome 2A (autosomal recessive, mild)
chr3_+_35697432	0.401	NM_198399	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chrX_-_106033202	0.400	NM_001171706 NM_138382	RIPPLY1	ripply1 homolog (zebrafish)
chr2_+_225973845	0.398	NM_020864	KIAA1486	KIAA1486
chr4_+_71142893	0.396	NM_005212	CSN3	casein kappa
chr6_+_54281161	0.394	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr4_-_44348414	0.394	NM_182592	YIPF7	Yip1 domain family, member 7
chr1_+_196874839	0.393		PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_+_34599163	0.392	NM_012153	EHF	ets homologous factor
chr3_-_196792059	0.391		APOD	apolipoprotein D
chr1_+_115373937	0.386	NM_000549	TSHB	thyroid stimulating hormone, beta
chr12_+_52680143	0.385	NM_006897	HOXC9	homeobox C9
chr11_+_64114857	0.383	NM_144585 NM_153378	SLC22A12	solute carrier family 22 (organic anion/urate transporter), member 12
chr2_+_158666627	0.383	NM_173355	UPP2	uridine phosphorylase 2
chr2_-_200030412	0.382		SATB2	SATB homeobox 2
chr5_+_169713458	0.381	NM_001034838	KCNIP1	Kv channel interacting protein 1
chr1_+_196874759	0.376	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr4_-_176970407	0.375		GPM6A	glycoprotein M6A
chr6_-_2696152	0.375	NM_001012418	MYLK4	myosin light chain kinase family, member 4
chr1_-_224195495	0.373	NM_001172425 NM_003240	LEFTY2	left-right determination factor 2
chr12_-_10497195	0.371	NM_002259 NM_007328	KLRC1	killer cell lectin-like receptor subfamily C, member 1
chr18_-_13905534	0.371	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr19_-_60941551	0.370	NM_176820	NLRP9	NLR family, pyrin domain containing 9
chr15_+_56217686	0.370	NM_020980	AQP9	aquaporin 9
chr17_-_70367479	0.369	NM_000835	GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr15_-_48434340	0.369		FLJ10038	hypothetical protein FLJ10038
chr4_+_46728051	0.367	NM_000812	GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1
chr1_+_108794426	0.364	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr6_+_154402135	0.363	NM_000914 NM_001008503 NM_001008504 NM_001008505 NM_001145282 NM_001145283 NM_001145285 NM_001145286 NM_001145284	OPRM1	opioid receptor, mu 1
chr7_-_83116414	0.360	NM_012431	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr5_+_140583098	0.360	NM_018934	PCDHB14	protocadherin beta 14
chr3_+_46370228	0.357	NM_001123041 NM_001123396	CCR2	chemokine (C-C motif) receptor 2
chr6_-_2580296	0.357	NM_152554	C6orf195	chromosome 6 open reading frame 195
chrX_-_65176564	0.357	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr11_-_89181390	0.355	NM_020358	TRIM49	tripartite motif containing 49
chr7_+_129693938	0.355	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chrX_-_142551587	0.352	NM_001184749	SLITRK4	SLIT and NTRK-like family, member 4
chr20_+_58064360	0.352	NM_173644	C20orf197	chromosome 20 open reading frame 197
chr1_+_109057078	0.351	NM_001144937	FNDC7	fibronectin type III domain containing 7
chr6_+_55300225	0.351	NM_207410	GFRAL	GDNF family receptor alpha like
chr18_+_27152049	0.349	NM_001942	DSG1	desmoglein 1
chr2_-_113526910	0.349	NM_014438 NM_173178	IL1F8	interleukin 1 family, member 8 (eta)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.73	4.27e-32	GO:0007600	sensory perception
3.46	1.96e-29	GO:0007608	sensory perception of smell
3.29	3.34e-29	GO:0007606	sensory perception of chemical stimulus
2.17	5.44e-27	GO:0050877	neurological system process
1.96	7.30e-24	GO:0003008	system process
1.39	1.51e-17	GO:0032501	multicellular organismal process
1.25	7.31e-09	GO:0050896	response to stimulus
1.56	4.16e-02	GO:0006955	immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.42	2.29e-15	GO:0005886	plasma membrane
1.41	4.28e-15	GO:0071944	cell periphery
1.31	9.99e-13	GO:0031224	intrinsic to membrane
1.31	4.73e-12	GO:0016021	integral to membrane
1.24	8.86e-10	GO:0044425	membrane part
1.50	5.55e-09	GO:0005576	extracellular region
1.53	4.24e-04	GO:0044421	extracellular region part
1.14	5.57e-04	GO:0016020	membrane
1.57	1.56e-03	GO:0005615	extracellular space
1.29	9.85e-03	GO:0044459	plasma membrane part
1.97	3.68e-02	GO:0045177	apical part of cell

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.60	2.00e-31	GO:0004984	olfactory receptor activity
2.17	3.24e-26	GO:0004888	transmembrane receptor activity
2.48	1.61e-25	GO:0004930	G-protein coupled receptor activity
1.94	5.07e-24	GO:0004872	receptor activity
1.72	1.80e-18	GO:0004871	signal transducer activity
1.72	1.80e-18	GO:0060089	molecular transducer activity
5.78	3.96e-03	GO:0004890	GABA-A receptor activity
4.99	1.70e-02	GO:0016917	GABA receptor activity
4.36	2.47e-02	GO:0015020	glucuronosyltransferase activity
2.92	2.50e-02	GO:0005254	chloride channel activity
2.74	3.65e-02	GO:0005253	anion channel activity