Mean activities

Top 10 and bottom 10 mean activities.

 Mean activities

Mean activities sorted by motif Z-value.

 Mean activities

Sorted mean activities for every motif.
Motif nameMean activityZ-ValueAssociated genesLogo
STAT5{A,B}.p2 0.495 0.521 STAT5B
STAT5A (MGF)
CREB1.p2 0.251 0.616 CREB1
NFIL3.p2 0.245 0.222 NFIL3 (E4BP4, NFIL3A, NF-IL3A)
RXRG_dimer.p3 0.232 0.219 NR1H2 (NER, NER-I, RIP15, LXR-b)
RXRA (NR2B1)
PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
PPARA (hPPAR, NR1C1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
ZNF143.p2 0.209 0.960 ZNF143 (SBF, pHZ-1, STAF)
RORA.p2 0.183 0.115 RORA (RZRA, ROR1, ROR2, ROR3, NR1F1)
TEAD1.p2 0.172 0.268 TEAD1 (TEF-1)
TEAD2 (ETF, TEF4, TEF-4, TEAD-2)
TEAD3 (TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3)
TEAD4 (TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B)
ELK1,4_GABP{A,B1}.p3 0.171 0.878 GABPA (E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A)
GABPB1 (E4TF1-47, GABPB)
ELK4 (SAP1)
ELK1
NRF1.p2 0.160 1.064 NRF1 (EWG, ALPHA-PAL)
FOX{D1,D2}.p2 0.150 0.267 FOXD2 (FREAC9)
FOXD1 (FREAC4)
CTCF.p2 0.143 0.288 CTCF
EHF.p2 0.140 0.553 EHF
GFI1.p2 0.138 0.472 GFI1
IRF1,2,7.p3 0.130 0.242 IRF1 (MAR, IRF-1)
IRF2 (IRF-2, DKFZp686F0244)
IRF7 (IRF7A, IRF-7H)
PRDM1.p3 0.130 0.122 PRDM1 (PRDI-BF1)
PAX2.p2 0.125 0.440 PAX2
FOS_FOS{B,L1}_JUN{B,D}.p2 0.122 0.233 FOS (c-fos, AP-1)
JUNB
FOSL1 (fra-1)
JUND (AP-1)
FOSB (G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818)
NKX2-2,8.p2 0.115 0.177 NKX2-2 (NKX2.2)
NKX2-8 (NKX2.8, Nkx2-9)
MYBL2.p2 0.114 0.144 MYBL2 (BMYB, B-MYB)
SOX{8,9,10}.p2 0.110 0.263 SOX9 (SRA1)
SOX8
SOX10 (DOM, WS4, WS2E)
FOXN1.p2 0.106 0.213 FOXN1 (FKHL20)
E2F1..5.p2 0.105 0.274 E2F4 (E2F-4)
E2F5
E2F2 (E2F-2)
E2F1 (RBP3)
E2F3
NKX6-1,2.p2 0.097 0.152 NKX6-1 (Nkx6.1)
NKX6-2 (NKX6B, GTX, NKX6.1)
NFY{A,B,C}.p2 0.093 0.425 NFYC (CBF-C)
NFYB (CBF-A, HAP3)
NFYA (HAP2, CBF-B)
ATF4.p2 0.086 0.192 ATF4 (TAXREB67, CREB-2)
TLX2.p2 0.085 0.223 TLX2 (Enx, Tlx2, NCX)
MYB.p2 0.079 0.260 MYB (c-myb)
FOXD3.p2 0.071 0.281 FOXD3 (Genesis, HFH2)
EWSR1-FLI1.p2 0.065 0.085 FLI1 (EWSR2, SIC-1)
EWSR1 (EWS, K984G1.4)
POU3F1..4.p2 0.063 0.065 POU3F1 (OCT6, SCIP)
POU3F3 (BRN1, OTF8)
POU3F2 (POUF3, BRN2, OCT7)
POU3F4 (BRN4, OTF9)
HBP1_HMGB_SSRP1_UBTF.p2 0.062 0.169 HMGB2
HMGB3 (HMG2A, MGC90319)
SSRP1 (FACT80)
UBTF (UBF, NOR-90)
HBP1
ELF1,2,4.p2 0.059 0.369 ELF2 (EU32, NERF, NERF-2, NERF-1A, NERF-1B)
ELF1
ELF4 (MEF, ELFR)
AIRE.p2 0.054 0.051 AIRE (PGA1, APS1)
TGIF1.p2 0.051 0.106 TGIF1
HES1.p2 0.050 0.229 HES1 (FLJ20408, HES-1, Hes1, bHLHb39)
MAFB.p2 0.048 0.323 MAFB
IKZF2.p2 0.047 0.145 IKZF2 (Helios)
ATF5_CREB3.p2 0.045 0.144 ATF5
CREB3 (LZIP, Luman)
TFEB.p2 0.044 0.111 TFEB
TFDP1.p2 0.043 0.675 TFDP1 (Dp-1, DRTF1, DP1)
STAT2,4,6.p2 0.042 0.153 STAT2 (STAT113)
STAT4
STAT6 (D12S1644, IL-4-STAT)
ZNF384.p2 0.041 0.137 ZNF384 (CAGH1A, CIZ, NMP4, NP)
PRRX1,2.p2 0.041 0.240 PRRX2 (PRX2, PMX2)
PRRX1 (PHOX1)
ESRRA.p2 0.039 0.070 ESRRA (ERR1, ERRalpha, NR3B1, ERRa)
BPTF.p2 0.038 0.249 BPTF (FAC1, NURF301)
YY1.p2 0.035 0.302 YY1 (NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S)
FOXQ1.p2 0.034 0.062 FOXQ1 (HFH1)
PAX5.p2 0.034 0.364 PAX5 (BSAP)
NKX3-2.p2 0.033 0.110 NKX3-2 (NKX3B, NKX3.2)
ESR1.p2 0.032 0.084 ESR1 (NR3A1, Era)
SP1.p2 0.027 0.392 SP1
ZBTB6.p2 0.026 0.100 ZBTB6 (ZID)
PITX1..3.p2 0.025 0.106 PITX2 (IGDS, RS, Brx1, Otlx2, ARP1)
PITX3
PITX1 (PTX1, POTX)
NKX2-1,4.p2 0.023 0.016 NKX2-1 (TTF-1)
NKX2-4 (NKX2.4)
XBP1.p3 0.023 0.027 XBP1
NFKB1_REL_RELA.p2 0.022 0.063 RELA (p65)
REL (I-Rel)
NFKB1 (KBF1, p105)
KLF4.p3 0.022 0.270 KLF4 (EZF, GKLF)
SPI1.p2 0.021 0.163 SPI1 (PU.1, SPI-A, OF, SFPI1, SPI-1)
SOX17.p2 0.018 0.052 SOX17
TFAP2B.p2 0.018 0.226 TFAP2B (AP2-B)
RBPJ.p2 0.017 0.031 RBPJ (SUH, IGKJRB, RBPJK, KBF2, RBP-J, CBF1)
LEF1_TCF7_TCF7L1,2.p2 0.016 0.030 TCF7 (TCF-1)
TCF7L2 (TCF-4)
LEF1 (TCF1ALPHA)
TCF7L1
GTF2I.p2 0.015 0.158 GTF2I (TFII-I, BAP-135, SPIN, BTKAP1, DIWS, IB291)
SRY.p2 0.013 0.036 SRY (TDF)
RFX1..5_RFXANK_RFXAP.p2 0.013 0.034 RFX1 (EF-C)
RFXAP
RFX5
RFXANK (BLS, RFX-B, ANKRA1, F14150_1, MGC138628)
RFX4
RFX3
RFX2 (FLJ14226)
CEBPA,B_DDIT3.p2 0.012 0.010 DDIT3 (CHOP10, GADD153, CHOP)
CEBPA (C/EBP-alpha)
CEBPB (LAP, CRP2, NFIL6, IL6DBP)
bHLH_family.p2 0.012 0.047 ARNTL (MOP3, JAP3, BMAL1, PASD3, bHLHe5)
MITF (WS2A, MI, bHLHe32)
MXI1 (MXD2, MAD2, MXI, bHLHc11)
TFE3 (TFEA, bHLHe33)
CLOCK (KIAA0334, KAT13D, bHLHe8)
OLIG2 (RACK17, OLIGO2, bHLHe19)
MXD4 (MAD4, MSTP149, MST149, bHLHc12)
HEY2 (bHLHb32)
HEY1 (HESR-1, CHF2, HESR1, HRT-1, CHF-2, HERP2, BHLHb31)
HEYL (bHLHb33)
MLXIPL (WS-bHLH, MIO, CHREBP, MONDOB)
HES6 (bHLHc23)
MXD3 (MAD3, bHLHc13)
ARNTL2 (BMAL2, MOP9, CLIF, PASD9, bHLHe6)
ID1 (dJ857M17.1.2, bHLHb24)
MNT (ROX, MXD6, MAD6, bHLHd3)
OLIG1 (BHLHB6, bHLHe21)
NPAS2 (MOP4, PASD4, bHLHe9)
TFAP4.p2 0.011 0.038 TFAP4 (AP-4)
HOX{A6,A7,B6,B7}.p2 0.010 0.076 HOXB6
HOXA7
HOXB7
HOXA6
ATF6.p2 0.009 0.022 ATF6 (ATF6A)
SPIB.p2 0.009 0.057 SPIB (SPI-B)
TFAP2{A,C}.p2 0.009 0.163 TFAP2C (AP2-GAMMA, ERF1, TFAP2G, hAP-2g)
TFAP2A (AP-2)
HIF1A.p2 0.008 0.025 HIF1A (MOP1, HIF-1alpha, PASD8, HIF1)
NFATC1..3.p2 0.007 0.021 NFATC3 (NFAT4, NFATX)
NFATC2 (NF-ATP, NFATp, NFAT1)
NFATC1 (NF-ATC, NFATc, NFAT2)
DMAP1_NCOR{1,2}_SMARC.p2 0.006 0.010 SMARCA1 (SNF2LB, NURF140, ISWI, SWI)
SMARCC2 (BAF170, Rsc8, CRACC2)
SMARCA5 (hSNF2H, hISWI, ISWI)
NCOR1 (N-CoR, hCIT529I10, TRAC1, hN-CoR, KIAA1047, MGC104216)
NCOR2 (SMRT, SMRTE, TRAC-1, CTG26, TNRC14)
DMAP1 (DNMAP1, FLJ11543, KIAA1425, DNMTAP1, EAF2, SWC4)
ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2 0.005 0.012 ARNT (HIF-1beta, bHLHe2)
MAX (bHLHd4)
MYC (c-Myc, bHLHe39)
USF1 (UEF, MLTFI, bHLHb11)
BHLHB2 (DEC1, bHLHe40)
ARNT2 (KIAA0307, bHLHe1)
HOX{A4,D4}.p2 0.004 0.008 HOXA4
HOXD4
IKZF1.p2 0.003 0.006 IKZF1 (hIk-1, LyF-1, Hs.54452, IKAROS)
FOXO1,3,4.p2 0.000 0.000 FOXO1 (FKH1)
FOXO4 (AFX1)
FOXO3 (AF6q21, FOXO2)
CRX.p2 -0.001 -0.002 CRX (CRD, LCA7, OTX3)
PATZ1.p2 -0.001 -0.017 PATZ1 (MAZR, dJ400N23, ZBTB19, ZSG, RIAZ, PATZ)
CDX1,2,4.p2 -0.002 -0.005 CDX1
CDX2
CDX4
HLF.p2 -0.002 -0.002 HLF (MGC33822)
HMX1.p2 -0.002 -0.006 HMX1 (H6, NKX5-3)
EP300.p2 -0.003 -0.012 EP300 (p300, KAT3B)
SPZ1.p2 -0.005 -0.023 SPZ1 (NYD-TSP1, FLJ25709)
ZBTB16.p2 -0.006 -0.017 ZBTB16 (PLZF)
POU5F1.p2 -0.007 -0.020 POU5F1 (OCT3, Oct4, MGC22487)
SOX2.p2 -0.008 -0.023 SOX2
ZFP161.p2 -0.008 -0.063 ZFP161 (ZNF478, ZBTB14)
SREBF1,2.p2 -0.011 -0.020 SREBF1 (SREBP1, bHLHd1)
SREBF2 (SREBP2, bHLHd2)
MAZ.p2 -0.012 -0.153 MAZ (ZF87, Pur-1, Zif87, ZNF801)
HIC1.p2 -0.013 -0.124 HIC1 (ZBTB29)
FEV.p2 -0.013 -0.068 FEV (PET-1, HSRNAFEV)
NHLH1,2.p2 -0.014 -0.089 NHLH1 (NSCL, NSCL1, bHLHa35)
NHLH2 (NSCL2, bHLHa34)
SRF.p3 -0.014 -0.014 SRF (MCM1)
NKX3-1.p2 -0.016 -0.021 NKX3-1 (NKX3.1, BAPX2)
EGR1..3.p2 -0.017 -0.127 EGR3 (PILOT)
EGR1 (TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225)
EGR2
SNAI1..3.p2 -0.017 -0.095 SNAI2 (SLUGH1)
SNAI1 (SNA, SLUGH2, SNAH)
SNAI3 (SMUC, Zfp293)
ZNF148.p2 -0.019 -0.115 ZNF148 (BERF-1, ZBP-89, BFCOL1, HT-BETA, ZFP148, pHZ-52)
AHR_ARNT_ARNT2.p2 -0.021 -0.111 ARNT (HIF-1beta, bHLHe2)
AHR
ARNT2 (KIAA0307, bHLHe1)
MZF1.p2 -0.022 -0.266 MZF1 (MZF1B, ZSCAN6, MZF-1, Zfp98)
ZEB1.p2 -0.023 -0.103 ZEB1 (BZP, ZEB, AREB6, NIL-2-A, Zfhep, Zfhx1a)
MEF2{A,B,C,D}.p2 -0.024 -0.055 MEF2A (RSRFC4, RSRFC9)
MEF2C
MEF2D
MEF2BNB-MEF2B (MEF2B, LOC729991-MEF2B)
MEF2B (RSRFR2, FLJ32648)
MYOD1.p2 -0.027 -0.101 MYOD1 (PUM, MYOD, bHLHc1)
FOX{F1,F2,J1}.p2 -0.029 -0.040 FOXF2 (FREAC2)
FOXJ1 (HFH-4, HFH4)
FOXF1 (FREAC1)
NKX2-3_NKX2-5.p2 -0.032 -0.053 NKX2-5 (CSX1, NKX2.5, NKX4-1)
NKX2-3 (NKX2.3, CSX3, NKX4-3)
RXR{A,B,G}.p2 -0.035 -0.127 RXRA (NR2B1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
GLI1..3.p2 -0.036 -0.092 GLI1
GLI2 (THP2, HPE9, THP1)
GLI3 (PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV)
TCF4_dimer.p2 -0.036 -0.210 TCF4 (E2-2, ITF2, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19, MGC149723, MGC149724)
NR1H4.p2 -0.038 -0.063 NR1H4 (FXR, RIP14, HRR1, HRR-1)
NFIX.p2 -0.039 -0.063 NFIX (NF1A)
HMGA1,2.p2 -0.040 -0.142 HMGA1
HMGA2 (BABL, LIPO)
MTF1.p2 -0.041 -0.281 MTF1
PAX6.p2 -0.041 -0.017 PAX6 (D11S812E, AN, WAGR)
TBX4,5.p2 -0.043 -0.108 TBX5
TBX4
FOXL1.p2 -0.047 -0.104 FOXL1 (FREAC7, FKH6)
PBX1.p2 -0.047 -0.060 PBX1
ZIC1..3.p2 -0.048 -0.133 ZIC1 (ZIC, ZNF201)
ZIC2 (HPE5)
ZIC3 (HTX, ZNF203)
EBF1.p2 -0.049 -0.158 EBF1 (OLF1)
LMO2.p2 -0.049 -0.188 LMO2 (TTG2, RHOM2, RBTN2)
PAX8.p2 -0.049 -0.008 PAX8
HSF1,2.p2 -0.049 -0.124 HSF1 (HSTF1)
HSF2
GATA1..3.p2 -0.051 -0.299 GATA1 (ERYF1, NFE1)
GATA2 (NFE1B)
GATA3 (HDR)
ATF2.p2 -0.051 -0.102 ATF2 (TREB7, CRE-BP1, HB16)
SOX5.p2 -0.051 -0.108 SOX5 (L-SOX5, MGC35153)
KLF12.p2 -0.052 -0.289 KLF12 (AP-2rep, HSPC122, AP2REP)
JUN.p2 -0.052 -0.150 JUN (c-Jun, AP-1)
JUND (AP-1)
JUNB
TFCP2.p2 -0.055 -0.290 TFCP2 (CP2, LSF, LBP-1C, TFCP2C)
DBP.p2 -0.055 -0.151 DBP (DABP)
ALX1.p2 -0.056 -0.077 ALX1
ADNP_IRX_SIX_ZHX.p2 -0.057 -0.144 SIX5
ZHX1
IRX4
ADNP (KIAA0784, ADNP1)
ZHX3 (KIAA0395)
ZHX2 (KIAA0854)
IRX5 (IRX-2a)
SIX2
ONECUT1,2.p2 -0.058 -0.088 ONECUT2 (OC-2)
ONECUT1 (HNF-6)
NFE2.p2 -0.062 -0.081 NFE2 (NF-E2)
T.p2 -0.062 -0.041 T
FOX{I1,J2}.p2 -0.062 -0.191 FOXI1 (FREAC6)
FOXJ2 (FHX)
STAT1,3.p3 -0.063 -0.048 STAT1 (STAT91, ISGF-3)
STAT3 (APRF)
ZNF423.p2 -0.064 -0.136 ZNF423 (KIAA0760, OAZ, Roaz, Ebfaz, Zfp104)
RREB1.p2 -0.065 -0.525 RREB1 (HNT)
NFE2L2.p2 -0.067 -0.082 NFE2L2 (NRF2)
ARID5B.p2 -0.068 -0.056 ARID5B (FLJ21150, MRF2)
EOMES.p2 -0.074 -0.100 EOMES (TBR2)
MYFfamily.p2 -0.075 -0.541 MYOD1 (PUM, MYOD, bHLHc1)
MYF6 (MRF4, bHLHc4)
MYF5 (bHLHc2)
MYOG (bHLHc3)
VSX1,2.p2 -0.075 -0.034 VSX2 (RET1)
VSX1 (PPD)
GTF2A1,2.p2 -0.077 -0.162 GTF2A1 (TFIIA)
GTF2A2 (TFIIA, HsT18745)
SMAD1..7,9.p2 -0.080 -0.218 SMAD5 (Dwfc, JV5-1)
SMAD1 (MADR1, JV4-1)
SMAD3 (JV15-2, HsT17436)
SMAD4 (DPC4)
SMAD2 (MADR2, JV18-1)
SMAD6 (HsT17432)
SMAD7
SMAD9
LHX3,4.p2 -0.086 -0.132 LHX3
LHX4 (Gsh4)
BACH2.p2 -0.094 -0.110 BACH2
ETS1,2.p2 -0.095 -0.389 ETS2
ETS1 (FLJ10768, ETS-1)
NFE2L1.p2 -0.099 -0.520 NFE2L1 (NRF1, LCR-F1, FLJ00380, TCF11)
CUX2.p2 -0.106 -0.054 CUX2 (KIAA0293, CDP2)
NR6A1.p2 -0.118 -0.067 NR6A1 (GCNF1, RTR)
NR5A1,2.p2 -0.118 -0.387 NR5A1 (FTZ1, SF-1, ELP, AD4BP)
NR5A2 (FTZ-F1beta, hB1F, LRH-1, FTZ-F1, hB1F-2, B1F2)
HNF4A_NR2F1,2.p2 -0.119 -0.410 NR2F1 (EAR-3, COUP-TFI, TCFCOUP1, SVP44)
NR2F2 (COUP-TFII, COUPTFB, SVP40)
HNF4A (NR2A1, HNF4)
NR3C1.p2 -0.122 -0.119 NR3C1 (GR)
TP53.p2 -0.132 -0.182 TP53 (p53, LFS1)
HOXA9_MEIS1.p2 -0.134 -0.085 MEIS1
HOXA9
CDC5L.p2 -0.136 -0.170 CDC5L (PCDC5RP, hCDC5, CEF1)
GFI1B.p2 -0.142 -0.147 GFI1B
POU6F1.p2 -0.145 -0.137 POU6F1 (BRN5, MPOU, TCFB1)
FOSL2.p2 -0.146 -0.216 FOSL2 (FRA2, FLJ23306)
TLX1..3_NFIC{dimer}.p2 -0.147 -0.245 TLX1
TLX3 (RNX)
ZNF238.p2 -0.151 -0.195 ZNF238 (C2H2-171, TAZ-1, RP58, ZBTB18)
FOXA2.p3 -0.154 -0.254 FOXA2
PAX4.p2 -0.160 -0.241 PAX4
NANOG.p2 -0.160 -0.181 NANOG (FLJ12581, FLJ40451)
POU2F1..3.p2 -0.165 -0.243 POU2F2 (OCT2)
POU2F1 (OCT1)
POU2F3 (OCT11, PLA-1, Skn-1a, Epoc-1)
PPARG.p2 -0.166 -0.119 PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
RXRA_VDR{dimer}.p2 -0.171 -0.138 VDR (NR1I1)
EVI1.p2 -0.171 -0.330 EVI1 (MDS1-EVI1, PRDM3)
POU1F1.p2 -0.178 -0.252 POU1F1 (GHF-1)
MSX1,2.p2 -0.184 -0.107 MSX1 (HYD1, OFC5)
MSX2 (CRS2, FPP, HOX8, MSH, PFM)
GATA6.p2 -0.187 -0.256 GATA6
NANOG{mouse}.p2 -0.191 -0.208 NANOG (FLJ12581, FLJ40451)
RUNX1..3.p2 -0.204 -0.481 RUNX1 (PEBP2A2, AMLCR1)
RUNX3 (AML2, PEBP2A3)
RUNX2 (AML3, PEBP2A1, PEBP2aA1)
PDX1.p2 -0.215 -0.094 PDX1 (IDX-1, STF-1, PDX-1, MODY4)
POU5F1_SOX2{dimer}.p2 -0.218 -0.260 POU5F1 (OCT3, Oct4, MGC22487)
SOX2
HOX{A5,B5}.p2 -0.263 -0.360 HOXB5
HOXA5
FOXP3.p2 -0.264 -0.201 FOXP3 (JM2, XPID, AIID, PIDX, DIETER, SCURFIN)
EN1,2.p2 -0.317 -0.423 EN1
EN2
HNF1A.p2 -0.319 -0.328 HNF1A (HNF1, LFB1)
HAND1,2.p2 -0.328 -0.416 HAND1 (eHand, Thing1, Hxt, bHLHa27)
HAND2 (dHand, Thing2, Hed, bHLHa26)
FOX{C1,C2}.p2 -0.366 -0.315 FOXC1 (FREAC3, ARA, IGDA, IHG1)
FOXC2 (MFH-1)
TAL1_TCF{3,4,12}.p2 -0.374 -0.268 TCF3 (E2A, ITF1, MGC129647, MGC129648, bHLHb21)
TCF4 (SEF2-1B, ITF2, bHLHb19)
TAL1 (SCL, bHLHa17)
TCF12 (HEB, HTF4, HsT17266, bHLHb20)
AR.p2 -0.466 -0.210 AR (AIS, NR3C4, SMAX1, HUMARA)
GZF1.p2 -0.471 -0.138 GZF1 (dJ322G13.2, ZBTB23)
TBP.p2 -0.493 -0.758 TBP (TFIID)
REST.p3 -0.649 -0.565 REST (NRSF, XBR)
PAX3,7.p2 -1.772 -0.247 PAX7 (Hup1)
PAX3 (HUP2)