Motif ID: SRY.p2

Z-value: 1.362


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y

Activity-expression correlation:

GenePromoterPearsonP-valuePlot


Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_106293112 2.863 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292932 2.743 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr9_+_126460511 2.728


chr6_+_105511615 2.305 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr1_-_47468029 2.160 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr8_-_108579270 2.080 NM_001146
ANGPT1
angiopoietin 1
chr6_-_49712483 1.910 NM_000324
RHAG
Rh-associated glycoprotein
chr7_+_106292975 1.904 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_+_135312655 1.672 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_-_19778928 1.417 NM_152774
TMEM196
transmembrane protein 196
chr11_-_16380967 1.379 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr3_+_39484073 1.352 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr12_-_101396459 1.314 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr10_+_104995633 1.284 NM_001143909
LOC729020
rcRPE
chr4_+_39874921 1.246 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_556968 1.203


chr8_-_42742729 1.189 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr4_+_35962038 1.164 NM_001170700
DTHD1
death domain containing 1
chr10_+_11246934 1.096 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr7_-_91632525 1.074 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chr1_+_66230977 1.068 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_171286634 1.037 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr7_-_135263737 1.027 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr5_+_121493113 1.024 NM_207317
ZNF474
zinc finger protein 474
chr8_-_82557956 1.023 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_-_158759606 1.013 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr2_-_56266408 1.012 LOC100129434
hypothetical LOC100129434
chr17_-_59817722 1.007 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr5_-_88155360 1.002 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr1_-_115039614 0.990 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr5_-_39400319 0.982 NM_001737
C9
complement component 9
chr3_+_142175329 0.977 SLC25A36
solute carrier family 25, member 36
chr17_-_59817575 0.977 PECAM1
platelet/endothelial cell adhesion molecule
chr21_-_14501114 0.963 NM_198996
LIPI
lipase, member I
chr1_+_196874867 0.959 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_+_120415958 0.950 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr17_-_36570508 0.937 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr7_+_120416103 0.919 C7orf58
chromosome 7 open reading frame 58
chr2_-_151854619 0.919 NM_004688
NMI
N-myc (and STAT) interactor
chr6_+_14033402 0.918 NM_001165033
RNF182
ring finger protein 182
chr7_+_113842284 0.913 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr2_-_162717159 0.903 NM_002054
GCG
glucagon
chr4_-_56153135 0.900 NM_152401
PDCL2
phosducin-like 2
chr1_+_111215343 0.875 NM_001040033
CD53
CD53 molecule
chr15_-_53349775 0.871 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr17_-_59817456 0.867 PECAM1
platelet/endothelial cell adhesion molecule
chr3_+_115495522 0.855 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr7_+_142590633 0.842 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr1_-_191422346 0.841 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_83108682 0.841 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_+_559129 0.838


chr1_+_196874759 0.825 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr11_+_113280727 0.824 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr12_-_89976261 0.814 NM_007035
KERA
keratocan
chr7_+_106897737 0.811 NM_005295
GPR22
G protein-coupled receptor 22
chr2_-_157890400 0.810 NM_020711
ERMN
ermin, ERM-like protein
chr18_-_13905534 0.805 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr3_+_179736917 0.805 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr4_+_71713324 0.797 NM_031889
ENAM
enamelin
chr12_-_101115677 0.794 NM_002674
PMCH
pro-melanin-concentrating hormone
chr9_+_76302071 0.791 NM_006914
RORB
RAR-related orphan receptor B
chr2_-_2313894 0.781 NM_015025
MYT1L
myelin transcription factor 1-like
chr12_-_69317441 0.781 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_-_85622366 0.780 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr10_+_11247059 0.769 CELF2
CUGBP, Elav-like family member 2
chr9_-_94226380 0.766 NM_005014
OMD
osteomodulin
chr5_-_83052606 0.763 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_-_20318578 0.755 NM_012400
PLA2G2D
phospholipase A2, group IID
chr8_+_40130143 0.754 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr10_+_70517823 0.751 NM_002727
SRGN
serglycin
chr2_+_102401580 0.750 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr11_+_5466490 0.745 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr11_+_5732498 0.741 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chrX_+_30171768 0.738 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr17_-_10313600 0.730 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr2_-_100088691 0.725 AFF3
AF4/FMR2 family, member 3
chr1_-_32574185 0.724 NM_023009
MARCKSL1
MARCKS-like 1
chr2_-_144768529 0.722 NM_001006636
GTDC1
glycosyltransferase-like domain containing 1
chr7_-_86526880 0.721 NM_001142749
KIAA1324L
KIAA1324-like
chr1_+_67404756 0.718 NM_144701
IL23R
interleukin 23 receptor
chr10_+_92970487 0.711 PCGF5
polycomb group ring finger 5
chr7_+_113853790 0.709 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr3_-_158703821 0.702 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr11_-_8921155 0.696 NM_020646
ASCL3
achaete-scute complex homolog 3 (Drosophila)
chr4_-_101658094 0.691 NM_001159694
NM_016242
EMCN

endomucin

chr8_-_30826074 0.688 NM_031271
TEX15
testis expressed 15
chrX_+_84385649 0.672 NM_021998
ZNF711
zinc finger protein 711
chr4_-_68432293 0.662 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr4_-_64957595 0.661 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr7_-_115458010 0.658 NM_001018058
NM_012252
TFEC

transcription factor EC

chr5_-_66528330 0.653 NM_005582
CD180
CD180 molecule
chrX_+_84385693 0.652 ZNF711
zinc finger protein 711
chr2_+_204509698 0.641 NM_012092
ICOS
inducible T-cell co-stimulator
chr17_-_30909219 0.637 NM_001129820
SLFN14
schlafen family member 14
chr3_-_167037861 0.632 BCHE
butyrylcholinesterase
chr2_+_102345528 0.631 NM_003855
IL18R1
interleukin 18 receptor 1
chr6_+_14032655 0.615 NM_001165034
RNF182
ring finger protein 182
chr7_-_88262966 0.615 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr1_+_196874839 0.611 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_-_104834344 0.609 LOC100506421
hypothetical LOC100506421
chr6_-_87861492 0.608 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr2_+_120233676 0.605 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr6_+_50894397 0.599 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr4_+_169250281 0.598 NM_007193
ANXA10
annexin A10
chr1_+_173111306 0.594 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_167037946 0.585 NM_000055
BCHE
butyrylcholinesterase
chr10_+_70517863 0.584 SRGN
serglycin
chr4_+_86918870 0.584 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr12_-_16321885 0.581 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr5_-_121842680 0.578


chr1_+_66570363 0.577 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_+_57964148 0.577


chr8_-_72436519 0.575 EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_25234582 0.570 NM_022150
NPVF
neuropeptide VF precursor
chr22_-_21231421 0.562 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr3_-_180452096 0.559 NM_014407
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_5925152 0.553 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr10_-_61570665 0.551 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_+_65300803 0.549 NM_001130860
NM_014799
HEPH

hephaestin

chr12_-_122272346 0.549 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr9_-_27287106 0.549 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr12_-_55614311 0.547 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr15_-_91078307 0.547 FAM174B
family with sequence similarity 174, member B
chr15_+_21361546 0.543 NM_005664
MKRN3
makorin ring finger protein 3
chr3_-_180452338 0.542 NM_171830
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_117762432 0.539 UBE4A
ubiquitination factor E4A (UFD2 homolog, yeast)
chr4_-_186934059 0.538 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr3_-_150533948 0.537 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr3_+_99733432 0.537 NM_005290
GPR15
G protein-coupled receptor 15
chr7_-_92693716 0.530 NM_001039372
HEPACAM2
HEPACAM family member 2
chr6_-_155818728 0.527 NM_015718
NOX3
NADPH oxidase 3
chr10_+_92970302 0.525 NM_032373
PCGF5
polycomb group ring finger 5
chr17_-_59817654 0.525 PECAM1
platelet/endothelial cell adhesion molecule
chr4_-_38482805 0.524 NM_003263
TLR1
toll-like receptor 1
chr17_-_64568641 0.522 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr16_-_45339605 0.521 NM_182493
MYLK3
myosin light chain kinase 3
chr14_+_19780737 0.517 NM_001004479
OR11H4
olfactory receptor, family 11, subfamily H, member 4
chr9_-_103237851 0.513 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr6_-_49820030 0.512 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr4_-_186969041 0.509 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr3_-_13032130 0.504


chr11_+_55869996 0.503 NM_001002907
OR8K1
olfactory receptor, family 8, subfamily K, member 1
chr17_-_44058612 0.501 NM_024017
HOXB9
homeobox B9
chr1_-_204455269 0.499 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr11_-_101292462 0.494 NM_178127
ANGPTL5
angiopoietin-like 5
chr11_+_5367182 0.494 NM_001004756
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr15_-_100280784 0.493 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr5_+_137231443 0.491 NM_001135940
NM_006790
MYOT

myotilin

chr3_+_180348818 0.490 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr5_+_76470829 0.489


chr11_-_113935789 0.487 NM_152315
FAM55A
family with sequence similarity 55, member A
chrX_+_79562601 0.487 NM_152630
FAM46D
family with sequence similarity 46, member D
chr7_-_107558021 0.486 NM_007356
LAMB4
laminin, beta 4
chr11_-_5766621 0.483 NM_001001913
OR52N1
olfactory receptor, family 52, subfamily N, member 1
chr12_-_8706533 0.483 MFAP5
microfibrillar associated protein 5
chr20_+_34635362 0.483 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr12_+_91620749 0.482 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr2_+_86801081 0.482 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr15_-_53350383 0.482 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr2_+_143351536 0.482 NM_001032998
NM_003937
KYNU

kynureninase

chr9_-_125070613 0.481 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr1_-_245763763 0.480 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr5_-_88215034 0.480 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr11_+_4799126 0.479 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr17_-_64649608 0.478 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr14_+_36196523 0.475 NM_006194
PAX9
paired box 9
chr19_+_56990222 0.475 NM_002030
FPR3
formyl peptide receptor 3
chr6_-_130072971 0.475 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr5_+_137231458 0.474 MYOT
myotilin
chr10_-_52315436 0.473 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr1_-_196776697 0.472 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr3_+_190372456 0.470 NM_198485
TPRG1
tumor protein p63 regulated 1
chr12_-_9651748 0.470 NM_002258
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr21_-_38792173 0.466 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr10_-_64246129 0.465 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr1_+_557269 0.464


chr11_+_66764060 0.463 LOC100131150
hypothetical protein LOC100131150
chr4_-_185376012 0.461 NM_153343
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr6_-_119137923 0.459 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr11_-_101906640 0.458 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr17_-_10265991 0.454 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr17_-_16816113 0.452 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr4_-_174774368 0.448 NM_006792
MORF4
mortality factor 4
chr10_+_92912676 0.447 PCGF5
polycomb group ring finger 5
chr21_-_14840506 0.446 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_+_51585834 0.444 NM_153228
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr3_+_44258381 0.444 NM_001145030
C3orf77
chromosome 3 open reading frame 77
chr7_+_102340579 0.442 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr11_+_22652894 0.442 NM_005256
GAS2
growth arrest-specific 2
chr3_+_4510160 0.441 ITPR1
inositol 1,4,5-triphosphate receptor, type 1
chr15_+_46285789 0.441 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr17_-_59451662 0.440 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr10_+_59764718 0.439 NM_003338
UBE2D1
ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
chr6_-_28663045 0.439 NM_052923
SCAND3
SCAN domain containing 3
chr6_-_139654807 0.438 NM_153235
TXLNB
taxilin beta
chr1_+_58899 0.438 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr4_-_139382672 0.438 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr14_-_52088786 0.437 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr9_-_14912419 0.435


chr4_+_41309690 0.435 LIMCH1
LIM and calponin homology domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.69 3.26e-05 GO:0007606 sensory perception of chemical stimulus
1.70 1.31e-04 GO:0007608 sensory perception of smell
1.43 2.58e-03 GO:0007600 sensory perception
1.13 1.95e-02 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.74 1.11e-05 GO:0004984 olfactory receptor activity
1.39 4.02e-03 GO:0004930 G-protein coupled receptor activity
1.26 6.80e-03 GO:0004872 receptor activity
1.29 1.47e-02 GO:0004888 transmembrane receptor activity