Motif ID: MAFB.p2

Z-value: 1.378


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_38751289-0.391.4e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_191453813 2.670 GLS
glutaminase
chr7_+_7188667 2.604 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr8_-_92122219 2.051 NM_018710
TMEM55A
transmembrane protein 55A
chrX_+_103297891 1.964 NM_207318
FAM199X
family with sequence similarity 199, X-linked
chr2_-_210744158 1.824 NM_152519
C2orf67
chromosome 2 open reading frame 67
chr2_-_192767494 1.823 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr20_-_30636535 1.795 LOC284804
hypothetical protein LOC284804
chrX_+_103297721 1.785 FAM199X
family with sequence similarity 199, X-linked
chr2_-_65210753 1.730 NM_004161
NM_015543
RAB1A

RAB1A, member RAS oncogene family

chrX_+_51503219 1.712 NM_018094
GSPT2
G1 to S phase transition 2
chr18_-_50004458 1.706 MBD2
methyl-CpG binding domain protein 2
chr13_-_29938029 1.706 NM_002128
HMGB1
high-mobility group box 1
chr2_-_65210695 1.664 RAB1A
RAB1A, member RAS oncogene family
chr6_-_111911106 1.617 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr13_-_29937966 1.609 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr2_+_177965734 1.515 AGPS
alkylglycerone phosphate synthase
chr12_-_38785871 1.492 NM_052885
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr4_-_15266042 1.491 FBXL5
F-box and leucine-rich repeat protein 5
chr1_-_243094431 1.481 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr8_-_31009858 1.467 NM_013357
PURG
purine-rich element binding protein G
chr6_+_163755658 1.461 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr4_+_153676857 1.416 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr2_+_114364306 1.413


chr2_+_191453792 1.398 GLS
glutaminase
chr1_-_109742020 1.388 NM_002959
SORT1
sortilin 1
chr1_-_21375939 1.363 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr4_-_15265993 1.349 FBXL5
F-box and leucine-rich repeat protein 5
chr1_-_67292286 1.347 SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr2_+_200484270 1.339 C2orf69
chromosome 2 open reading frame 69
chr5_+_179854029 1.272 CNOT6
CCR4-NOT transcription complex, subunit 6
chr8_-_66916197 1.253 NM_002604
PDE7A
phosphodiesterase 7A
chr4_-_15266072 1.240 NM_001193534
NM_001193535
NM_012161
FBXL5


F-box and leucine-rich repeat protein 5


chr13_-_50925134 1.215 INTS6
integrator complex subunit 6
chr2_+_191453791 1.213 NM_014905
GLS
glutaminase
chr2_-_174537354 1.210 SP3
Sp3 transcription factor
chr1_+_39229474 1.204 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr5_+_129268352 1.192 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr2_-_39201066 1.162 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr6_-_169866011 1.158 NM_018288
NM_133325
PHF10

PHD finger protein 10

chr5_-_95323353 1.156 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr8_+_64243662 1.127 NM_152758
YTHDF3
YTH domain family, member 3
chr6_+_150112511 1.123 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_-_11917305 1.115 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr2_+_99320181 1.109 NM_015904
EIF5B
eukaryotic translation initiation factor 5B
chr7_-_150385867 1.100 CDK5
cyclin-dependent kinase 5
chr1_+_166414706 1.094 NM_001031800
NM_152902
TIPRL

TIP41, TOR signaling pathway regulator-like (S. cerevisiae)

chr6_+_150112537 1.091 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_+_27795633 1.089 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr5_+_179853977 1.084 NM_015455
CNOT6
CCR4-NOT transcription complex, subunit 6
chr1_-_243094404 1.081 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr20_-_33793507 1.070 RBM39
RNA binding motif protein 39
chr2_-_153282104 1.056 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr2_+_200484219 1.051 NM_153689
C2orf69
chromosome 2 open reading frame 69
chr17_-_53420595 1.046 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr7_-_104440707 1.046 LOC100216545
hypothetical LOC100216545
chr7_+_21434097 1.034 NM_003112
SP4
Sp4 transcription factor
chr12_+_61147083 1.030 MON2
MON2 homolog (S. cerevisiae)
chr2_+_200528720 1.024 C2orf47
chromosome 2 open reading frame 47
chr7_+_77005287 1.021 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr1_-_243094414 1.013 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_+_100590640 1.012 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr2_-_183610992 1.008 NCKAP1
NCK-associated protein 1
chr20_-_33793286 1.004 RBM39
RNA binding motif protein 39
chr7_-_150385912 1.003 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr2_-_55130925 0.997 RTN4
reticulon 4
chr6_-_111910799 0.992 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr14_+_49157150 0.989 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr3_-_88190737 0.988 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr5_+_72179685 0.984 NM_153188
TNPO1
transportin 1
chr16_-_11917069 0.983


chr2_+_191454157 0.982 GLS
glutaminase
chr12_-_78852815 0.981 PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr20_-_33793591 0.979 RBM39
RNA binding motif protein 39
chr17_-_25642962 0.972 NM_000386
BLMH
bleomycin hydrolase
chr2_-_161058120 0.972 RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_-_139382672 0.972 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr1_-_52791309 0.966 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr8_+_64243741 0.954 YTHDF3
YTH domain family, member 3
chr12_-_78853057 0.944 NM_002480
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr2_-_174537021 0.943 NM_001017371
SP3
Sp3 transcription factor
chr6_-_86409701 0.936 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr2_+_191454036 0.932 GLS
glutaminase
chr2_+_79593679 0.930 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr1_-_153799186 0.925 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr14_+_57835028 0.923 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr1_+_100590595 0.920 NM_003672
NM_033312
NM_033313
CDC14A


CDC14 cell division cycle 14 homolog A (S. cerevisiae)


chr1_+_110328830 0.919 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr2_+_177965617 0.918 NM_003659
AGPS
alkylglycerone phosphate synthase
chr2_-_55130963 0.910 RTN4
reticulon 4
chr12_-_106011437 0.906 CRY1
cryptochrome 1 (photolyase-like)
chr7_+_77163665 0.905 NM_198467
RSBN1L
round spermatid basic protein 1-like
chr12_-_109505505 0.894 PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr6_-_76051159 0.890 TMEM30A
transmembrane protein 30A
chr6_+_150112549 0.889 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_-_11917235 0.888 GSPT1
G1 to S phase transition 1
chr6_-_76051197 0.886 TMEM30A
transmembrane protein 30A
chr3_-_15875932 0.885 NM_015199
ANKRD28
ankyrin repeat domain 28
chr2_+_114364177 0.884 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr6_-_108688918 0.871 SNX3
sorting nexin 3
chr2_-_88707978 0.870 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr3_-_114947681 0.866 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_+_31616196 0.865 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr6_-_76051216 0.865 TMEM30A
transmembrane protein 30A
chr3_+_31549478 0.864 NM_178862
STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr10_-_17536181 0.861 NM_001004470
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr7_-_126819953 0.859 NM_176814
ZNF800
zinc finger protein 800
chr18_-_46977103 0.856 MEX3C
mex-3 homolog C (C. elegans)
chrX_+_40325173 0.856 ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr4_-_74343169 0.849


chr20_-_32163576 0.848 EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr4_+_166348219 0.839 NM_007246
KLHL2
kelch-like 2, Mayven (Drosophila)
chr12_-_106011715 0.839 NM_004075
CRY1
cryptochrome 1 (photolyase-like)
chr20_+_34206070 0.838 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr10_+_96152262 0.834 TBC1D12
TBC1 domain family, member 12
chr1_-_52791218 0.833 ZCCHC11
zinc finger, CCHC domain containing 11
chr7_-_27206249 0.830 NM_000522
HOXA13
homeobox A13
chrX_+_40325089 0.829 NM_005765
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr2_+_114364169 0.829 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr5_-_36187710 0.828 NM_001007527
LMBRD2
LMBR1 domain containing 2
chr22_-_35428848 0.828 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr1_+_42920683 0.827 YBX1
Y box binding protein 1
chr13_-_78878380 0.824 RBM26
RNA binding motif protein 26
chr2_-_159021201 0.818 NM_001171637
NM_138803
CCDC148

coiled-coil domain containing 148

chr13_+_48447954 0.815 NM_001079673
FNDC3A
fibronectin type III domain containing 3A
chr2_+_200528173 0.812 NM_024520
C2orf47
chromosome 2 open reading frame 47
chr14_+_57834962 0.812 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr7_-_17946523 0.808 SNX13
sorting nexin 13
chr2_-_192767844 0.806 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_+_87566738 0.803 NM_006769
LMO4
LIM domain only 4
chr2_-_65210552 0.801 RAB1A
RAB1A, member RAS oncogene family
chr14_-_22891263 0.801 NM_020372
SLC22A17
solute carrier family 22, member 17
chr2_+_200484251 0.800 C2orf69
chromosome 2 open reading frame 69
chr1_-_21375891 0.798 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr10_-_98336584 0.797 TM9SF3
transmembrane 9 superfamily member 3
chr13_+_27610379 0.796 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_200528703 0.794 NM_001039693
C2orf60
chromosome 2 open reading frame 60
chr20_-_48980858 0.790 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr15_-_56829069 0.785 ADAM10
ADAM metallopeptidase domain 10
chr5_-_95323180 0.784 ELL2
elongation factor, RNA polymerase II, 2
chr11_-_10786875 0.782 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr1_-_243093833 0.779 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr10_+_69314944 0.778 NM_001142498
SIRT1
sirtuin 1
chr11_-_10787028 0.774 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr10_-_74526596 0.771 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr7_-_120823556 0.768 FAM3C
family with sequence similarity 3, member C
chr1_+_40399642 0.767 RLF
rearranged L-myc fusion
chr6_-_85530617 0.765 NM_001080508
TBX18
T-box 18
chr8_+_66719441 0.765 NM_001145839
NM_014637
MTFR1

mitochondrial fission regulator 1

chr1_+_40399618 0.763 NM_012421
RLF
rearranged L-myc fusion
chr16_-_47873183 0.761 NM_004352
CBLN1
cerebellin 1 precursor
chr17_-_28228184 0.758 MYO1D
myosin ID
chr1_-_153798776 0.755 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_111483771 0.754 NM_001007794
CEPT1
choline/ethanolamine phosphotransferase 1
chr5_+_138921041 0.754 UBE2D2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr20_-_32163743 0.754 NM_003908
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr4_+_57469122 0.753 REST
RE1-silencing transcription factor
chr8_+_125556130 0.751 NM_007218
RNF139
ring finger protein 139
chr6_-_108688817 0.748 SNX3
sorting nexin 3
chr8_+_125556374 0.748 RNF139
ring finger protein 139
chr3_-_69212192 0.746 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr2_-_39201631 0.746 SOS1
son of sevenless homolog 1 (Drosophila)
chr12_-_74711474 0.745 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr18_-_42751305 0.742 NM_004671
NM_173206
PIAS2

protein inhibitor of activated STAT, 2

chr6_-_150080912 0.741 LATS1
LATS, large tumor suppressor, homolog 1 (Drosophila)
chr3_-_123716471 0.739 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr12_+_22669275 0.739 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr6_-_76051351 0.738 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chrX_-_119329334 0.738 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr17_-_24645289 0.738 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr13_+_25726238 0.737 CDK8
cyclin-dependent kinase 8
chr10_+_69314714 0.731 SIRT1
sirtuin 1
chr2_-_161058550 0.730 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_+_114364139 0.729 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr8_-_67253234 0.729 NM_000756
CRH
corticotropin releasing hormone
chr1_+_26310854 0.726 NM_152835
PDIK1L
PDLIM1 interacting kinase 1 like
chr12_+_65949327 0.724 NM_018448
CAND1
cullin-associated and neddylation-dissociated 1
chr2_-_61969248 0.721 NM_006430
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr8_-_125454097 0.718 NM_194291
TMEM65
transmembrane protein 65
chr1_-_32176275 0.715 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_+_114364133 0.715 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr8_-_102287083 0.715 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr6_+_76368337 0.715 NM_001100409
NM_015571
SENP6

SUMO1/sentrin specific peptidase 6

chr12_+_100615530 0.712 NM_020244
CHPT1
choline phosphotransferase 1
chr6_+_71434192 0.709 NM_001044305
NM_021940
SMAP1

small ArfGAP 1

chr14_+_102870431 0.708 EIF5
eukaryotic translation initiation factor 5
chr14_-_90596484 0.706


chr5_+_173247919 0.705 NM_030627
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr16_+_51722285 0.704 CHD9
chromodomain helicase DNA binding protein 9
chr5_+_138921287 0.703 UBE2D2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr14_+_32478209 0.703 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr15_-_53667800 0.702 PYGO1
pygopus homolog 1 (Drosophila)
chr6_+_155096494 0.702 SCAF8
SR-related CTD-associated factor 8
chr11_-_10835941 0.695 NM_001143667
NM_021211
ZBED5

zinc finger, BED-type containing 5

chr2_+_202024636 0.694 NM_018571
STRADB
STE20-related kinase adaptor beta
chrX_-_119329307 0.691 FAM70A
family with sequence similarity 70, member A
chr16_-_67921925 0.687 NM_022341
PDF
peptide deformylase (mitochondrial)
chr17_-_36570508 0.687 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr9_-_76832844 0.687 C9orf41
chromosome 9 open reading frame 41
chr7_-_120823591 0.685 NM_001040020
NM_014888
FAM3C

family with sequence similarity 3, member C

chr14_+_49304533 0.683 NM_014315
KLHDC2
kelch domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 4.78e-24 GO:0044260 cellular macromolecule metabolic process
1.11 2.72e-20 GO:0009987 cellular process
1.20 1.32e-19 GO:0044237 cellular metabolic process
1.36 1.70e-19 GO:0044267 cellular protein metabolic process
1.22 5.00e-17 GO:0043170 macromolecule metabolic process
1.17 2.78e-14 GO:0044238 primary metabolic process
1.36 5.95e-13 GO:0006464 protein modification process
1.27 2.57e-12 GO:0019538 protein metabolic process
1.34 6.27e-12 GO:0043412 macromolecule modification
1.14 6.28e-12 GO:0008152 metabolic process
1.66 5.76e-11 GO:0016071 mRNA metabolic process
1.61 4.32e-09 GO:0044265 cellular macromolecule catabolic process
1.13 3.23e-08 GO:0050794 regulation of cellular process
1.53 5.78e-08 GO:0009057 macromolecule catabolic process
1.26 1.71e-07 GO:0048523 negative regulation of cellular process
1.71 1.75e-07 GO:0070647 protein modification by small protein conjugation or removal
1.12 2.78e-07 GO:0050789 regulation of biological process
1.76 4.88e-07 GO:0032446 protein modification by small protein conjugation
1.22 6.00e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 8.43e-07 GO:0065007 biological regulation
1.24 1.32e-06 GO:0048519 negative regulation of biological process
1.28 3.53e-06 GO:0016070 RNA metabolic process
1.63 5.03e-06 GO:0030163 protein catabolic process
1.34 6.82e-06 GO:0044248 cellular catabolic process
1.66 1.20e-05 GO:0006511 ubiquitin-dependent protein catabolic process
1.72 1.78e-05 GO:0016567 protein ubiquitination
1.58 1.94e-05 GO:0006397 mRNA processing
1.62 2.69e-05 GO:0044257 cellular protein catabolic process
1.62 3.07e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.63 3.49e-05 GO:0043632 modification-dependent macromolecule catabolic process
1.62 4.63e-05 GO:0019941 modification-dependent protein catabolic process
1.67 4.90e-05 GO:0010608 posttranscriptional regulation of gene expression
1.30 6.36e-05 GO:0051641 cellular localization
1.18 6.55e-05 GO:0034641 cellular nitrogen compound metabolic process
1.50 7.26e-05 GO:0006325 chromatin organization
1.17 8.30e-05 GO:0006807 nitrogen compound metabolic process
1.57 1.14e-04 GO:0016568 chromatin modification
1.17 2.22e-04 GO:0060255 regulation of macromolecule metabolic process
1.32 2.23e-04 GO:0042981 regulation of apoptosis
1.42 2.33e-04 GO:0051276 chromosome organization
1.21 2.77e-04 GO:0090304 nucleic acid metabolic process
2.21 2.80e-04 GO:0000956 nuclear-transcribed mRNA catabolic process
1.16 3.03e-04 GO:0071840 cellular component organization or biogenesis
1.32 3.31e-04 GO:0032268 regulation of cellular protein metabolic process
2.15 3.50e-04 GO:0006402 mRNA catabolic process
1.32 3.58e-04 GO:0043067 regulation of programmed cell death
1.16 5.17e-04 GO:0031323 regulation of cellular metabolic process
1.31 5.40e-04 GO:0010941 regulation of cell death
1.30 6.22e-04 GO:0051246 regulation of protein metabolic process
1.16 6.38e-04 GO:0016043 cellular component organization
1.15 6.64e-04 GO:0080090 regulation of primary metabolic process
1.14 8.14e-04 GO:0019222 regulation of metabolic process
1.18 8.54e-04 GO:0071842 cellular component organization at cellular level
1.18 1.11e-03 GO:0071841 cellular component organization or biogenesis at cellular level
2.16 1.38e-03 GO:0031123 RNA 3'-end processing
1.25 1.43e-03 GO:0009056 catabolic process
1.22 1.54e-03 GO:0010467 gene expression
1.95 1.63e-03 GO:0006401 RNA catabolic process
2.43 2.02e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1.75 3.03e-03 GO:0006417 regulation of translation
1.38 3.14e-03 GO:0006396 RNA processing
1.34 3.33e-03 GO:0046907 intracellular transport
1.24 3.69e-03 GO:0007399 nervous system development
1.72 4.67e-03 GO:0043687 post-translational protein modification
1.28 5.69e-03 GO:0008104 protein localization
1.17 5.71e-03 GO:0010468 regulation of gene expression
1.38 5.72e-03 GO:0042060 wound healing
1.27 6.26e-03 GO:0051649 establishment of localization in cell
1.18 6.91e-03 GO:0048522 positive regulation of cellular process
1.30 8.26e-03 GO:0048468 cell development
1.41 9.56e-03 GO:0007596 blood coagulation
1.41 9.56e-03 GO:0050817 coagulation
2.16 1.08e-02 GO:0031124 mRNA 3'-end processing
1.39 1.38e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.40 1.45e-02 GO:0007599 hemostasis
1.29 1.52e-02 GO:0022008 neurogenesis
1.30 1.79e-02 GO:0048699 generation of neurons
1.24 1.86e-02 GO:0033036 macromolecule localization
1.27 1.91e-02 GO:0006793 phosphorus metabolic process
1.27 1.91e-02 GO:0006796 phosphate metabolic process
1.17 2.10e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 2.61e-02 GO:0072523 purine-containing compound catabolic process
1.56 3.02e-02 GO:0006195 purine nucleotide catabolic process
1.54 3.06e-02 GO:0009166 nucleotide catabolic process
1.16 3.07e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.57 4.34e-02 GO:0009261 ribonucleotide catabolic process
1.33 4.86e-02 GO:0051726 regulation of cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.28e-35 GO:0044424 intracellular part
1.12 3.77e-32 GO:0005622 intracellular
1.13 1.72e-21 GO:0043229 intracellular organelle
1.13 2.25e-21 GO:0043226 organelle
1.15 2.67e-21 GO:0005737 cytoplasm
1.14 1.58e-19 GO:0043231 intracellular membrane-bounded organelle
1.14 2.34e-19 GO:0043227 membrane-bounded organelle
1.19 5.28e-16 GO:0005634 nucleus
1.24 7.65e-14 GO:0032991 macromolecular complex
1.26 3.32e-13 GO:0043234 protein complex
1.16 3.11e-12 GO:0044444 cytoplasmic part
1.17 9.38e-12 GO:0044446 intracellular organelle part
1.16 3.45e-11 GO:0044422 organelle part
1.27 1.89e-09 GO:0044428 nuclear part
1.24 8.94e-08 GO:0031974 membrane-enclosed lumen
1.24 1.72e-07 GO:0043233 organelle lumen
1.25 1.79e-07 GO:0005829 cytosol
1.27 3.29e-07 GO:0031981 nuclear lumen
1.23 4.88e-07 GO:0070013 intracellular organelle lumen
1.29 1.01e-05 GO:0005654 nucleoplasm
1.68 2.64e-05 GO:0000785 chromatin
1.03 1.05e-04 GO:0044464 cell part
1.03 1.11e-04 GO:0005623 cell
1.41 1.77e-04 GO:0005694 chromosome
1.35 4.14e-04 GO:0044451 nucleoplasm part
1.22 8.18e-04 GO:0012505 endomembrane system
1.16 1.34e-03 GO:0043228 non-membrane-bounded organelle
1.16 1.34e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.40 2.42e-03 GO:0044427 chromosomal part
2.32 6.02e-03 GO:0017053 transcriptional repressor complex
1.25 1.45e-02 GO:0005794 Golgi apparatus
1.53 1.58e-02 GO:0016604 nuclear body
1.32 1.69e-02 GO:0044431 Golgi apparatus part
1.41 2.67e-02 GO:0005815 microtubule organizing center
1.94 3.63e-02 GO:0034399 nuclear periphery
1.80 4.53e-02 GO:0016585 chromatin remodeling complex
1.35 4.79e-02 GO:0005768 endosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 2.79e-30 GO:0005515 protein binding
1.09 9.19e-18 GO:0005488 binding
1.27 8.57e-10 GO:0000166 nucleotide binding
1.71 1.99e-07 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.26 4.10e-07 GO:0032553 ribonucleotide binding
1.26 4.10e-07 GO:0032555 purine ribonucleotide binding
1.26 5.10e-07 GO:0017076 purine nucleotide binding
1.54 1.11e-06 GO:0016874 ligase activity
1.71 2.11e-06 GO:0016881 acid-amino acid ligase activity
1.39 3.38e-06 GO:0003723 RNA binding
1.28 3.67e-06 GO:0032559 adenyl ribonucleotide binding
1.28 3.83e-06 GO:0030554 adenyl nucleotide binding
1.25 5.42e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.39 2.09e-05 GO:0019899 enzyme binding
1.26 2.41e-05 GO:0005524 ATP binding
1.68 5.16e-05 GO:0019787 small conjugating protein ligase activity
1.14 1.80e-03 GO:0003676 nucleic acid binding
1.61 2.17e-03 GO:0004842 ubiquitin-protein ligase activity
1.10 1.46e-02 GO:0003824 catalytic activity
3.19 2.44e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.43 2.72e-02 GO:0042578 phosphoric ester hydrolase activity