Motif ID: MAFB.p2

Z-value: 1.378


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_38751289-0.391.4e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_191453813 2.670 GLS
glutaminase
chr7_+_7188667 2.604 NM_020156
 C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr8_-_92122219 2.051 NM_018710
 TMEM55A
transmembrane protein 55A
chrX_+_103297891 1.964 NM_207318
 FAM199X
family with sequence similarity 199, X-linked
chr2_-_210744158 1.824 NM_152519
 C2orf67
chromosome 2 open reading frame 67
chr2_-_192767494 1.823 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr20_-_30636535 1.795 LOC284804
hypothetical protein LOC284804
chrX_+_103297721 1.785 FAM199X
family with sequence similarity 199, X-linked
chr2_-_65210753 1.730 NM_004161
NM_015543
 RAB1A

RAB1A, member RAS oncogene family

chrX_+_51503219 1.712 NM_018094
 GSPT2
G1 to S phase transition 2
chr18_-_50004458 1.706 MBD2
methyl-CpG binding domain protein 2
chr13_-_29938029 1.706 NM_002128
 HMGB1
high-mobility group box 1
chr2_-_65210695 1.664 RAB1A
RAB1A, member RAS oncogene family
chr6_-_111911106 1.617 NM_002912
 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr13_-_29937966 1.609 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr2_+_177965734 1.515 AGPS
alkylglycerone phosphate synthase
chr12_-_38785871 1.492 NM_052885
 SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr4_-_15266042 1.491 FBXL5
F-box and leucine-rich repeat protein 5
chr1_-_243094431 1.481 NM_004501
NM_031844
 HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr8_-_31009858 1.467 NM_013357
 PURG
purine-rich element binding protein G

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 87 entries
enrichment   p-value GO term description
2.43 2.02e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
2.21 2.80e-04 GO:0000956 nuclear-transcribed mRNA catabolic process
2.16 1.38e-03 GO:0031123 RNA 3'-end processing
2.16 1.08e-02 GO:0031124 mRNA 3'-end processing
2.15 3.50e-04 GO:0006402 mRNA catabolic process
1.95 1.63e-03 GO:0006401 RNA catabolic process
1.76 4.88e-07 GO:0032446 protein modification by small protein conjugation
1.75 3.03e-03 GO:0006417 regulation of translation
1.72 1.78e-05 GO:0016567 protein ubiquitination
1.72 4.67e-03 GO:0043687 post-translational protein modification
1.71 1.75e-07 GO:0070647 protein modification by small protein conjugation or removal
1.67 4.90e-05 GO:0010608 posttranscriptional regulation of gene expression
1.66 5.76e-11 GO:0016071 mRNA metabolic process
1.66 1.20e-05 GO:0006511 ubiquitin-dependent protein catabolic process
1.63 5.03e-06 GO:0030163 protein catabolic process
1.63 3.49e-05 GO:0043632 modification-dependent macromolecule catabolic process
1.62 2.69e-05 GO:0044257 cellular protein catabolic process
1.62 3.07e-05 GO:0051603 proteolysis involved in cellular protein catabolic process
1.62 4.63e-05 GO:0019941 modification-dependent protein catabolic process
1.61 4.32e-09 GO:0044265 cellular macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.32 6.02e-03 GO:0017053 transcriptional repressor complex
1.94 3.63e-02 GO:0034399 nuclear periphery
1.80 4.53e-02 GO:0016585 chromatin remodeling complex
1.68 2.64e-05 GO:0000785 chromatin
1.53 1.58e-02 GO:0016604 nuclear body
1.41 1.77e-04 GO:0005694 chromosome
1.41 2.67e-02 GO:0005815 microtubule organizing center
1.40 2.42e-03 GO:0044427 chromosomal part
1.35 4.14e-04 GO:0044451 nucleoplasm part
1.35 4.79e-02 GO:0005768 endosome
1.32 1.69e-02 GO:0044431 Golgi apparatus part
1.29 1.01e-05 GO:0005654 nucleoplasm
1.27 1.89e-09 GO:0044428 nuclear part
1.27 3.29e-07 GO:0031981 nuclear lumen
1.26 3.32e-13 GO:0043234 protein complex
1.25 1.79e-07 GO:0005829 cytosol
1.25 1.45e-02 GO:0005794 Golgi apparatus
1.24 7.65e-14 GO:0032991 macromolecular complex
1.24 8.94e-08 GO:0031974 membrane-enclosed lumen
1.24 1.72e-07 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
3.19 2.44e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.71 1.99e-07 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.71 2.11e-06 GO:0016881 acid-amino acid ligase activity
1.68 5.16e-05 GO:0019787 small conjugating protein ligase activity
1.61 2.17e-03 GO:0004842 ubiquitin-protein ligase activity
1.54 1.11e-06 GO:0016874 ligase activity
1.43 2.72e-02 GO:0042578 phosphoric ester hydrolase activity
1.39 3.38e-06 GO:0003723 RNA binding
1.39 2.09e-05 GO:0019899 enzyme binding
1.28 3.67e-06 GO:0032559 adenyl ribonucleotide binding
1.28 3.83e-06 GO:0030554 adenyl nucleotide binding
1.27 8.57e-10 GO:0000166 nucleotide binding
1.26 4.10e-07 GO:0032553 ribonucleotide binding
1.26 4.10e-07 GO:0032555 purine ribonucleotide binding
1.26 5.10e-07 GO:0017076 purine nucleotide binding
1.26 2.41e-05 GO:0005524 ATP binding
1.25 5.42e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.21 2.79e-30 GO:0005515 protein binding
1.14 1.80e-03 GO:0003676 nucleic acid binding
1.10 1.46e-02 GO:0003824 catalytic activity