Motif ID: VSX1,2.p2

Z-value: 0.428


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VSX2chr14_+_737759270.638.3e-03Click!
VSX1chr20_-_250107560.116.9e-01Click!


Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_17861266 0.349 NM_001105569
MSGN1
mesogenin 1
chr1_-_203592538 0.294 NM_018203
KLHDC8A
kelch domain containing 8A
chr20_+_58004811 0.291 NM_021810
CDH26
cadherin 26
chr4_+_88790477 0.272 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr8_+_92330691 0.265 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr14_-_94306104 0.252 NM_173849
GSC
goosecoid homeobox
chr9_+_12764988 0.222 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr5_+_127012611 0.212 NM_001048252
CTXN3
cortexin 3
chr12_+_15590552 0.209 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr11_-_57173823 0.207 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr6_-_33016561 0.187 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr3_-_109730858 0.179 NM_014981
MYH15
myosin, heavy chain 15
chr3_+_182900081 0.164 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr7_+_37689903 0.157


chr16_+_11966464 0.147 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_52016270 0.143 NM_001173467
SP7
Sp7 transcription factor
chrX_-_21586337 0.141 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr19_+_9064854 0.137 NM_001004456
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr10_+_44726635 0.134 NM_001123376
TMEM72
transmembrane protein 72
chr2_-_217268492 0.133 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr3_+_123256902 0.133 NM_175862
CD86
CD86 molecule
chrX_+_43400385 0.130 MAOA
monoamine oxidase A
chr18_+_59705918 0.114 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr8_+_22266256 0.112 PIWIL2
piwi-like 2 (Drosophila)
chr8_+_67201684 0.112 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr1_+_158426908 0.111 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_-_149004852 0.109 CTSS
cathepsin S
chr4_+_169654742 0.104 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr1_+_100776280 0.099 NM_022049
GPR88
G protein-coupled receptor 88
chr3_+_113200696 0.099 NM_001008273
TAGLN3
transgelin 3
chr4_+_120029426 0.096 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr7_+_2524022 0.093 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_36403910 0.092 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr3_+_110024234 0.091 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr9_-_19778590 0.087 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chrX_+_43400475 0.085 MAOA
monoamine oxidase A
chr6_+_49575629 0.085 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr1_-_156635879 0.079 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chr3_-_127810087 0.078 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr1_-_150653351 0.074 NM_016190
CRNN
cornulin
chr11_+_59920062 0.074 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr12_-_51233001 0.073 NM_033448
KRT71
keratin 71
chr4_-_138673014 0.072 PCDH18
protocadherin 18
chr10_+_32896656 0.071 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr1_+_175406685 0.071 FAM5B
family with sequence similarity 5, member B
chr11_+_59979857 0.070 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr4_+_78651929 0.070 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr11_-_30910074 0.067 NM_020869
DCDC5
doublecortin domain containing 5
chr2_-_80384997 0.066 NM_178839
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr9_+_130428519 0.065 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr5_-_24535386 0.065 NM_001190450
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_+_196874839 0.064 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_-_20138445 0.064 NM_001029865
DBX1
developing brain homeobox 1
chr11_+_59804634 0.063 NM_148975
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4
chr6_+_127940011 0.063 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr12_-_25041639 0.060 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr14_-_21172837 0.060 NM_001005466
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr4_-_74704964 0.060 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr10_-_69736600 0.059 PBLD
phenazine biosynthesis-like protein domain containing
chr8_-_42742729 0.058 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chrX_+_7147471 0.058 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr10_+_24795446 0.056 KIAA1217
KIAA1217
chr8_-_10550026 0.054 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr11_-_102250876 0.054 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr2_-_80385227 0.053 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr18_-_65775139 0.053 NM_006566
CD226
CD226 molecule
chr6_-_112033752 0.052 TRAF3IP2
TRAF3 interacting protein 2
chr16_-_20246309 0.050 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr7_+_1239078 0.048 NM_001080461
UNCX
UNC homeobox
chr6_-_166960690 0.048 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_207512522 0.048 NM_173077
CPO
carboxypeptidase O
chr8_-_87824996 0.047 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr1_+_111571803 0.045 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr18_+_44319365 0.045 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr1_-_158098962 0.044 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr7_+_50318801 0.044 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr7_-_83662152 0.043 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_-_55815113 0.043 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr1_+_198263352 0.042 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr17_+_18027816 0.041 ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr8_+_9990471 0.041 NM_001135671
MSRA
methionine sulfoxide reductase A
chr2_+_202379442 0.040 NM_139158
CDK15
cyclin-dependent kinase 15
chr11_-_4371463 0.039 NM_003141
TRIM21
tripartite motif containing 21
chr4_-_169476391 0.039 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr11_+_17697685 0.038 NM_002478
MYOD1
myogenic differentiation 1
chr1_+_144183811 0.037 ANKRD34A
ankyrin repeat domain 34A
chr6_+_160462852 0.037 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr1_-_184684478 0.037 NM_022576
PDC
phosducin
chr2_-_80384454 0.036 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr12_+_18305740 0.036 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr1_+_28134090 0.036 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr3_+_99350859 0.035 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr17_-_71448700 0.035 NM_001080542
FBF1
Fas (TNFRSF6) binding factor 1
chr2_+_189547358 0.034 COL3A1
collagen, type III, alpha 1
chr4_-_122357104 0.034 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr14_+_31868229 0.034 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr14_-_59264044 0.032 NM_206857
RTN1
reticulon 1
chr11_+_26972203 0.032 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)
chr1_-_27825633 0.031 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr10_+_96433240 0.031 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr14_+_75058591 0.029 BATF
basic leucine zipper transcription factor, ATF-like
chr7_+_141457977 0.029 LOC93432
maltase-glucoamylase-like pseudogene
chr12_-_4358968 0.029 NM_020638
FGF23
fibroblast growth factor 23
chr6_+_29534109 0.028 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr1_+_205293217 0.028 NM_001018053
NM_006212
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr2_-_218739891 0.028 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr15_-_70350609 0.027 NM_020214
PARP6
poly (ADP-ribose) polymerase family, member 6
chr3_-_166278969 0.027 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr13_-_34948758 0.027 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_28458546 0.027 NM_031459
SESN2
sestrin 2
chr1_+_117345894 0.027 NM_004258
CD101
CD101 molecule
chr22_+_39789945 0.027


chr11_+_26972244 0.026 FIBIN
fin bud initiation factor homolog (zebrafish)
chr11_-_128567302 0.025 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr16_+_47965308 0.025 NM_144602
C16orf78
chromosome 16 open reading frame 78
chrX_+_107174855 0.025 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr2_-_190635566 0.025 NM_005259
MSTN
myostatin
chr1_+_220977180 0.025 NM_207468
FAM177B
family with sequence similarity 177, member B
chr11_-_89181390 0.024 NM_020358
TRIM49
tripartite motif containing 49
chrX_-_138617994 0.024 NM_001099855
NM_001171876
MCF2

MCF.2 cell line derived transforming sequence

chrX_+_48978875 0.023 CCDC22
coiled-coil domain containing 22
chr6_-_112034166 0.023 NM_001164281
NM_147686
TRAF3IP2

TRAF3 interacting protein 2

chr1_+_242582559 0.023 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chr9_+_66197108 0.022


chr5_-_96504194 0.022 LIX1
Lix1 homolog (chicken)
chr19_-_45611110 0.022 NM_020956
NM_181882
PRX

periaxin

chr5_+_36642424 0.022 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_25234582 0.021 NM_022150
NPVF
neuropeptide VF precursor
chr1_-_108032645 0.020 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chrX_+_48978870 0.020 NM_014008
CCDC22
coiled-coil domain containing 22
chrX_-_24600661 0.020 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_-_116973465 0.020 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr3_+_113200275 0.019 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr2_-_65013070 0.018 LOC400958
hypothetical LOC400958
chr9_-_21067804 0.018 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr11_+_59580630 0.017 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr10_-_50066386 0.016 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr1_-_156816312 0.016 NM_001004477
OR10X1
olfactory receptor, family 10, subfamily X, member 1
chrX_+_79562601 0.016 NM_152630
FAM46D
family with sequence similarity 46, member D
chr11_-_128399218 0.015 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr12_+_15590811 0.015 PTPRO
protein tyrosine phosphatase, receptor type, O
chr3_+_116824840 0.015 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr5_-_56814310 0.014 NM_001017992
ACTBL2
actin, beta-like 2
chr3_-_102522093 0.014 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr9_-_135923373 0.014 BRD3
bromodomain containing 3
chr1_+_173111306 0.014 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chrX_-_23835868 0.014 NM_024122
APOO
apolipoprotein O
chr16_+_31178812 0.014 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr3_-_48634192 0.013 NM_001008269
TMEM89
transmembrane protein 89
chr3_+_196933422 0.012 NM_152673
MUC20
mucin 20, cell surface associated
chr16_+_4322225 0.012 NM_032575
GLIS2
GLIS family zinc finger 2
chr2_-_99238001 0.012 NM_175735
LYG2
lysozyme G-like 2
chr4_-_66218777 0.012 EPHA5
EPH receptor A5
chr8_+_39911630 0.012 NM_194294
IDO2
indoleamine 2,3-dioxygenase 2
chr15_-_53349775 0.012 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr12_+_103677388 0.012 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chrX_-_19727828 0.012 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr6_+_31604717 0.011 NM_001011700
MCCD1
mitochondrial coiled-coil domain 1
chr19_-_41514390 0.011


chr8_-_134156437 0.011 SLA
Src-like-adaptor
chr4_-_100284395 0.010 NM_000670
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr20_-_49852353 0.010 NM_020436
SALL4
sal-like 4 (Drosophila)
chr4_-_68793928 0.010 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr4_-_57242492 0.010 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr19_-_40711034 0.010 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr10_-_48036698 0.010 NM_016204
GDF2
growth differentiation factor 2
chr5_-_96504216 0.009 LIX1
Lix1 homolog (chicken)
chr12_-_54392328 0.009 NM_001144997
ITGA7
integrin, alpha 7
chr8_-_117837224 0.009 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr8_-_117837240 0.008 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr11_+_71578606 0.008 NM_000802
FOLR1
folate receptor 1 (adult)
chr15_-_40236061 0.007 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr6_-_87861492 0.007 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr15_+_97990705 0.007 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr6_-_166960649 0.007 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_+_95362334 0.006 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr3_+_161040343 0.005 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr8_+_54926920 0.005 NM_170587
RGS20
regulator of G-protein signaling 20
chr12_+_91620749 0.005 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr16_-_87280380 0.004 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr5_-_111119846 0.004 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr11_+_59580705 0.004 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr15_-_64644758 0.003 NM_207338
LCTL
lactase-like
chr12_+_67366989 0.003 NM_020401
NUP107
nucleoporin 107kDa
chr17_-_36165050 0.003 NM_181534
KRT25
keratin 25
chr11_-_16454493 0.003 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr7_+_113853790 0.002 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr13_-_33148899 0.002 STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_-_123596921 0.002 NM_000586
IL2
interleukin 2
chr11_-_36576352 0.002 NM_000536
RAG2
recombination activating gene 2
chr3_-_168674502 0.002 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr4_+_141397889 0.001 NM_032547
SCOC
short coiled-coil protein
chrX_+_55951280 0.001


chr8_-_52884456 0.001 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.58 7.26e-03 GO:0032501 multicellular organismal process
5.31 3.67e-02 GO:0007517 muscle organ development

Nothing significant found in compartment category.

Nothing significant found in function category.