Motif ID: CDC5L.p2

Z-value: 0.902


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44463418-0.097.3e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_165804157 0.735 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_-_160764819 0.716 NM_000888
ITGB6
integrin, beta 6
chrX_-_15312390 0.652 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr15_+_100175888 0.571 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chr13_-_85271329 0.518 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr18_-_35634247 0.514 LOC647946
hypothetical LOC647946
chr13_-_109600709 0.510 COL4A1
collagen, type IV, alpha 1
chr1_-_20682541 0.508


chr14_+_38772870 0.505 NM_054024
MIA2
melanoma inhibitory activity 2
chr8_+_75899326 0.485 NM_015886
PI15
peptidase inhibitor 15
chr2_-_160765008 0.461 ITGB6
integrin, beta 6
chr11_+_101488380 0.452 NM_001195045
YAP1
Yes-associated protein 1
chr8_+_22266256 0.452 PIWIL2
piwi-like 2 (Drosophila)
chr2_+_119416214 0.444 NM_006770
MARCO
macrophage receptor with collagenous structure
chr19_-_10558906 0.434 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr17_-_34377150 0.423 NM_001008777
FBXO47
F-box protein 47
chr2_+_211166323 0.415 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr18_+_59593591 0.410 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_156876798 0.407 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr1_-_202402043 0.403 NM_000537
REN
renin
chr2_+_61243132 0.370 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr10_+_96688399 0.368 NM_000771
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr4_-_15549047 0.368 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr20_-_13919256 0.362 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr14_-_80934523 0.360 NM_033104
STON2
stonin 2
chr12_+_21059896 0.360 NM_001009562
LST-3TM12
organic anion transporter LST-3b
chr12_+_18305740 0.358 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr10_-_21226536 0.354 NM_006393
NEBL
nebulette
chr19_+_16691786 0.352 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr4_+_74825138 0.343 NM_000584
IL8
interleukin 8
chr7_-_122627235 0.342 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr6_-_71069347 0.330 NM_001851
COL9A1
collagen, type IX, alpha 1
chr17_-_2913650 0.322 NM_014566
OR1D4
OR1D5
olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
olfactory receptor, family 1, subfamily D, member 5
chr18_+_59705918 0.321 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr3_+_123526700 0.321 NM_005213
CSTA
cystatin A (stefin A)
chr12_-_38300109 0.312 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr1_+_151270301 0.308 NM_003125
SPRR1B
small proline-rich protein 1B
chr3_+_108578877 0.303 NM_032600
CCDC54
coiled-coil domain containing 54
chr6_-_136889302 0.296 MAP7
microtubule-associated protein 7
chr3_+_142175329 0.294 SLC25A36
solute carrier family 25, member 36
chr3_+_190831909 0.287 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr8_+_32623792 0.286 NM_013959
NRG1
neuregulin 1
chrX_+_100111352 0.286 NM_001012990
NM_001162490
NM_001162491
ARL13A


ADP-ribosylation factor-like 13A


chr20_-_1420168 0.285 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr4_+_53986759 0.283 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr5_+_145296313 0.283 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr14_-_20128228 0.282 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr5_-_125956996 0.282 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr9_+_104797413 0.280 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr2_-_2314087 0.277 MYT1L
myelin transcription factor 1-like
chr3_+_103636548 0.274 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr3_-_152517204 0.274 NM_023915
GPR87
G protein-coupled receptor 87
chr14_-_60818263 0.271 NM_001017970
TMEM30B
transmembrane protein 30B
chr2_+_64540843 0.269 HSPC159
galectin-related protein
chr16_-_70168449 0.267 NM_000353
TAT
tyrosine aminotransferase
chr20_+_43764068 0.265 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr12_-_51114372 0.256 NM_004693
KRT75
keratin 75
chr10_-_90601655 0.254 NM_144590
ANKRD22
ankyrin repeat domain 22
chr11_+_55343658 0.253 NM_001001952
OR5D18
olfactory receptor, family 5, subfamily D, member 18
chr10_-_116276560 0.252 ABLIM1
actin binding LIM protein 1
chr12_-_10433852 0.251 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr6_-_136888771 0.251 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chrX_+_99726445 0.250 NM_022144
TNMD
tenomodulin
chr9_+_22436783 0.250 NM_022160
DMRTA1
DMRT-like family A1
chrX_-_24600661 0.249 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr4_+_62045433 0.248 NM_015236
LPHN3
latrophilin 3
chr9_-_111230926 0.248 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr2_-_215605054 0.247 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr9_-_21067804 0.246 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr12_-_74010071 0.246 NM_032606
CAPS2
calcyphosine 2
chr17_+_38256710 0.245 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr4_+_71142893 0.244 NM_005212
CSN3
casein kappa
chr20_+_10363949 0.241 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chrX_+_110252960 0.240 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr2_-_162808123 0.240 NM_004460
FAP
fibroblast activation protein, alpha
chrX_-_23835868 0.239 NM_024122
APOO
apolipoprotein O
chr3_-_9266251 0.238 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr2_+_204279624 0.236 CD28
CD28 molecule
chr12_+_54080480 0.236 NM_001005518
OR6C65
olfactory receptor, family 6, subfamily C, member 65
chrX_+_102918409 0.232 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr2_-_225078931 0.228 CUL3
cullin 3
chr12_+_10222823 0.227 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr6_-_32665409 0.227 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr3_+_191588354 0.226 NM_006580
CLDN16
claudin 16
chr9_+_12764988 0.225 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr20_-_18425811 0.224 NM_006606
RBBP9
retinoblastoma binding protein 9
chr14_+_19365447 0.222 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr4_-_159313167 0.220 NM_016613
FAM198B
family with sequence similarity 198, member B
chr14_+_69307914 0.219 SRSF5
serine/arginine-rich splicing factor 5
chr15_+_30721161 0.219 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr4_+_69465107 0.216 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chrX_-_19598912 0.215 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr2_-_21106291 0.215 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_+_113648020 0.214 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr17_-_36209672 0.214 NM_181535
KRT28
keratin 28
chr10_-_116276651 0.211 NM_006720
ABLIM1
actin binding LIM protein 1
chr2_+_204279442 0.210 NM_006139
CD28
CD28 molecule
chr9_-_21358005 0.210 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr4_-_70760381 0.207 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr4_+_88939725 0.204 NM_004967
IBSP
integrin-binding sialoprotein
chrX_+_102918453 0.204 PLP1
proteolipid protein 1
chr14_+_61532293 0.203 NM_031914
SYT16
synaptotagmin XVI
chr4_-_177427252 0.203 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr1_-_67366807 0.201 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr2_-_215711313 0.200 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_+_210152609 0.200 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr6_-_25679197 0.200


chr7_+_18502342 0.199 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr1_+_246178701 0.198 NM_001001963
OR2L8
olfactory receptor, family 2, subfamily L, member 8
chr6_+_55147029 0.197 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr2_+_38031099 0.192 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr5_+_94752803 0.191 NM_152548
FAM81B
family with sequence similarity 81, member B
chr10_-_116434364 0.188 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr8_+_104380234 0.186 NM_001164616
NM_003506
FZD6

frizzled homolog 6 (Drosophila)

chr15_+_60146467 0.184 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr12_-_66905802 0.184 NM_018402
IL26
interleukin 26
chr2_-_215949566 0.183 FN1
fibronectin 1
chr5_+_145297490 0.182 SH3RF2
SH3 domain containing ring finger 2
chr6_-_116973465 0.178 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr16_+_74868676 0.176 NM_033401
CNTNAP4
contactin associated protein-like 4
chr21_-_30774502 0.176 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr7_+_80105858 0.176 CD36
CD36 molecule (thrombospondin receptor)
chr9_+_5880801 0.174 NM_005511
MLANA
melan-A
chr13_+_31211678 0.172 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr5_+_140146059 0.171 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr8_-_107851593 0.170 NM_139166
ABRA
actin-binding Rho activating protein
chr1_+_89602023 0.169 NM_198460
GBP6
guanylate binding protein family, member 6
chr1_+_84382529 0.169 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_116434102 0.167 ABLIM1
actin binding LIM protein 1
chr20_-_19984685 0.166 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr12_-_242255 0.163 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr2_+_113648036 0.161 PSD4
pleckstrin and Sec7 domain containing 4
chr3_-_168853982 0.161 NM_178824
WDR49
WD repeat domain 49
chr17_-_36451189 0.161 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr12_-_15706340 0.161 EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_207995999 0.160 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr14_-_70071484 0.159 NM_003814
ADAM20
ADAM metallopeptidase domain 20
chr21_-_30460841 0.159 NM_012131
CLDN17
claudin 17
chrX_-_131089552 0.157 NM_194277
FRMD7
FERM domain containing 7
chr3_-_113495763 0.156 NM_183061
SLC9A10
solute carrier family 9, member 10
chr9_+_66293049 0.156 MGC21881
hypothetical locus MGC21881
chr11_+_1816808 0.156 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr5_+_54434230 0.155 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr4_-_23500706 0.155 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_-_133008834 0.154 NM_138327
TAAR1
trace amine associated receptor 1
chr9_-_94206648 0.153 NM_014057
NM_033014
OGN

osteoglycin

chr2_-_73781974 0.153 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr8_-_49996353 0.153 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr15_+_39853982 0.152 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr2_+_101874809 0.152 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_234624266 0.151 NM_145861
EDARADD
EDAR-associated death domain
chr2_-_207291364 0.150 NM_001093730
DYTN
dystrotelin
chr11_-_117640166 0.150 MPZL2
myelin protein zero-like 2
chr18_-_49944986 0.150 MBD2
methyl-CpG binding domain protein 2
chr7_+_29486010 0.149 NM_001039936
CHN2
chimerin (chimaerin) 2
chr16_+_27248806 0.149 IL4R
interleukin 4 receptor
chr7_+_18501876 0.149 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr3_-_131081910 0.147 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chrX_+_85404626 0.147 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr12_+_16391795 0.147 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr1_-_150328153 0.146 NM_001008536
TCHHL1
trichohyalin-like 1
chr10_+_126620681 0.146 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr12_-_16652202 0.145 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_162189090 0.145 NM_001178015
NM_001178016
NM_022058
SLC4A10


solute carrier family 4, sodium bicarbonate transporter, member 10


chr20_+_42417502 0.144 HNF4A
hepatocyte nuclear factor 4, alpha
chr2_+_101874765 0.144 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_145163779 0.143 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr11_-_113971607 0.143 FAM55D
family with sequence similarity 55, member D
chr11_+_111552298 0.142 NM_001037290
BCO2
beta-carotene oxygenase 2
chr11_+_34599163 0.141 NM_012153
EHF
ets homologous factor
chr2_+_228386800 0.141 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr9_-_15240113 0.139 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr4_+_38740246 0.138 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr12_+_13240987 0.138 EMP1
epithelial membrane protein 1
chr18_+_606671 0.137 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr15_+_69626594 0.136 THSD4
thrombospondin, type I, domain containing 4
chr1_+_63861474 0.135 NM_001172818
PGM1
phosphoglucomutase 1
chr11_+_111551417 0.134 NM_031938
BCO2
beta-carotene oxygenase 2
chr10_-_94247450 0.134 NM_001165946
IDE
insulin-degrading enzyme
chr7_+_94135384 0.133 PEG10
paternally expressed 10
chr10_+_90414125 0.133 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr5_+_68549380 0.133 MRPS36
mitochondrial ribosomal protein S36
chr3_-_157755559 0.132 SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr5_+_140719773 0.132 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr4_-_152368492 0.131 SH3D19
SH3 domain containing 19
chr2_-_2313894 0.130 NM_015025
MYT1L
myelin transcription factor 1-like
chr5_+_147628567 0.129 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr11_-_117640078 0.128


chr2_+_102744921 0.128 NM_144632
TMEM182
transmembrane protein 182
chr8_-_87824996 0.127 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr3_-_198784590 0.126 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr2_+_101981888 0.126 NM_173343
IL1R2
interleukin 1 receptor, type II
chrX_+_27674846 0.125 NM_001136533
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr6_-_165643064 0.124 NM_144980
C6orf118
chromosome 6 open reading frame 118
chr11_-_128242342 0.124 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr8_+_87180248 0.124 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr6_-_32605898 0.124 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr5_+_147423727 0.123 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr2_+_73973640 0.123 ACTG2
actin, gamma 2, smooth muscle, enteric
chr12_+_20739555 0.122 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1




Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.55 1.40e-04 GO:0005576 extracellular region
1.28 7.01e-03 GO:0071944 cell periphery
1.26 2.54e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.48 1.73e-04 GO:0004867 serine-type endopeptidase inhibitor activity
3.34 4.93e-04 GO:0030414 peptidase inhibitor activity
3.19 3.18e-03 GO:0004866 endopeptidase inhibitor activity
3.06 5.70e-03 GO:0061135 endopeptidase regulator activity
2.80 8.25e-03 GO:0061134 peptidase regulator activity
2.18 9.35e-03 GO:0004984 olfactory receptor activity
2.34 2.14e-02 GO:0004857 enzyme inhibitor activity