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Motif ID: PAX6.p2

Z-value: 0.229

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_123925343	0.329	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)
chr5_-_141318810	0.309	NM_016580	PCDH12	protocadherin 12
chr2_+_214984705	0.280	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chrX_-_148604506	0.242	NM_001011544	MAGEA11	melanoma antigen family A, 11
chr5_+_57823017	0.208	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chrX_-_65176564	0.185	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr7_+_154943466	0.169	NM_001427	EN2	engrailed homeobox 2
chr10_-_82039158	0.155	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr12_-_69317441	0.153	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr5_-_135259403	0.143	NM_000590	IL9	interleukin 9
chr4_-_64957595	0.128	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr4_+_130236731	0.121	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chr1_+_108794426	0.120	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr1_-_108588186	0.117	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr12_+_8557402	0.117	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr5_-_22248630	0.117		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr15_+_49760841	0.114	NM_001165257 NM_013243	SCG3	secretogranin III
chr1_-_246804680	0.112	NM_001001821	OR2T34	olfactory receptor, family 2, subfamily T, member 34
chr5_+_147672181	0.112	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr3_-_152585226	0.100	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr12_-_43555607	0.098	NM_001145109	NELL2	NEL-like 2 (chicken)
chr1_+_246703249	0.096	NM_001005495	OR2T3	olfactory receptor, family 2, subfamily T, member 3
chr8_+_39911630	0.093	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr6_-_64087806	0.090	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr16_-_11282595	0.081	NM_002761	PRM1	protamine 1
chr5_+_180399871	0.081		BTNL9	butyrophilin-like 9
chr1_+_87153025	0.080		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr6_-_42270671	0.080	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr12_-_68379331	0.075	NM_032735	BEST3	bestrophin 3
chr4_-_26100986	0.073	NM_000730	CCKAR	cholecystokinin A receptor
chr5_+_180399830	0.073	NM_152547	BTNL9	butyrophilin-like 9
chr5_+_79651545	0.072	NM_032567	SPZ1	spermatogenic leucine zipper 1
chr6_+_25760352	0.071	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr16_-_46823682	0.070	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr4_+_187385618	0.069	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr19_+_15920817	0.068	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr11_+_55776251	0.064	NM_001004747	OR5T3	olfactory receptor, family 5, subfamily T, member 3
chr11_+_117452995	0.064		TMPRSS4	transmembrane protease, serine 4
chr16_+_70654625	0.062	NM_020995	HPR	haptoglobin-related protein
chr18_+_17076166	0.062	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr12_+_108035424	0.059
chr1_+_61697209	0.057		NFIA	nuclear factor I/A
chr3_-_196792059	0.055		APOD	apolipoprotein D
chrX_-_106336199	0.054	NM_017681	NUP62CL	nucleoporin 62kDa C-terminal like
chr8_-_7710547	0.053	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr3_+_109498082	0.052		HHLA2	HERV-H LTR-associating 2
chr1_+_207944807	0.051	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr2_-_133256097	0.051		NCKAP5	NCK-associated protein 5
chr6_-_10520264	0.048		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr11_+_111294868	0.047		C11orf52	chromosome 11 open reading frame 52
chr14_+_28311740	0.047		C14orf23	chromosome 14 open reading frame 23
chr8_+_124264054	0.046		FAM83A	family with sequence similarity 83, member A
chr11_+_4859624	0.046	NM_001004759	OR51T1	olfactory receptor, family 51, subfamily T, member 1
chr6_-_10520592	0.046	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_-_148605996	0.043	NM_001168379	ZIC4	Zic family member 4
chr17_-_33602374	0.043	NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr10_+_18280773	0.040	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr21_-_38792173	0.040	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr16_+_70646008	0.040	NM_001126102 NM_005143	HP	haptoglobin
chr3_-_129668780	0.039	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr17_-_36294962	0.038	NM_019010	KRT20	keratin 20
chr3_-_150533948	0.038	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr6_+_167624792	0.038	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr11_-_5178505	0.037	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr15_+_27001131	0.037	NM_001130414 NM_005503	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr5_+_40945315	0.037	NM_000587	C7	complement component 7
chr8_-_21827057	0.036	NM_003974	DOK2	docking protein 2, 56kDa
chr17_-_36276987	0.036	NM_000223	KRT12	keratin 12
chr5_+_55182963	0.036	NM_139017	IL31RA	interleukin 31 receptor A
chrX_-_130251068	0.035	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr1_-_209732881	0.035	NM_001164688 NM_183059	RD3	retinal degeneration 3
chrX_+_52797004	0.035	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chrX_-_130250880	0.033		IGSF1	immunoglobulin superfamily, member 1
chr17_-_31831093	0.033	NM_001123392 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3H TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H TBC1 domain family, member 3F
chr8_+_21972804	0.033		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr20_+_31713750	0.033	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr15_-_48192804	0.033		ATP8B4	ATPase, class I, type 8B, member 4
chr9_-_94206648	0.032	NM_014057 NM_033014	OGN	osteoglycin
chr4_-_10295412	0.032	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr17_+_22982344	0.032		LGALS9	lectin, galactoside-binding, soluble, 9
chr14_-_87806913	0.030	NM_138318	KCNK10	potassium channel, subfamily K, member 10
chr22_-_48865907	0.030	NM_139202	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_115538716	0.030	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr11_-_49960646	0.029	NM_001005270	OR4C12	olfactory receptor, family 4, subfamily C, member 12
chr11_+_14883118	0.028		CALCB	calcitonin-related polypeptide beta
chrX_-_15242589	0.028	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr13_+_52500830	0.028	NM_006418	OLFM4	olfactomedin 4
chr9_-_115901157	0.027	NM_138424	KIF12	kinesin family member 12
chr5_+_121493113	0.027	NM_207317	ZNF474	zinc finger protein 474
chr2_-_157890400	0.026	NM_020711	ERMN	ermin, ERM-like protein
chr6_+_152168500	0.025	NM_001122741	ESR1	estrogen receptor 1
chrX_-_6156655	0.025	NM_181332	NLGN4X	neuroligin 4, X-linked
chrX_+_50670474	0.025	NM_005448	BMP15	bone morphogenetic protein 15
chrX_+_92815667	0.025	NM_001171109 NM_001171110 NM_001171111 NM_173698	FAM133A	family with sequence similarity 133, member A
chr10_+_35934343	0.025	NM_153368	GJD4	gap junction protein, delta 4, 40.1kDa
chr17_+_8154864	0.025	NM_025014	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr11_+_111294810	0.024	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr6_-_155818728	0.024	NM_015718	NOX3	NADPH oxidase 3
chr11_-_123130435	0.024	NM_001005188	OR6X1	olfactory receptor, family 6, subfamily X, member 1
chr6_-_28591542	0.024	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chr17_+_8154280	0.023	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr1_-_12830728	0.023	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr8_-_59575249	0.023	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chrX_-_52700674	0.022	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr19_+_56990222	0.021	NM_002030	FPR3	formyl peptide receptor 3
chr17_+_55854636	0.021	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr3_+_16949585	0.020	NM_015184	PLCL2	phospholipase C-like 2
chr19_-_56825400	0.019	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr17_-_31528027	0.019	NM_001001417	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr17_-_33552166	0.019	NM_001123391 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr10_+_118340460	0.018	NM_006229	PNLIPRP1	pancreatic lipase-related protein 1
chr1_-_245902965	0.018	NM_001005487	OR13G1	olfactory receptor, family 13, subfamily G, member 1
chr4_+_71261066	0.018	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr12_-_131725848	0.018		POLE	polymerase (DNA directed), epsilon
chr22_+_24468168	0.018		MYO18B	myosin XVIIIB
chr12_+_119224506	0.017	NM_012240	SIRT4	sirtuin 4
chr11_+_123600553	0.016	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr5_-_79982584	0.016	NM_001190470	MTRNR2L2	MT-RNR2-like 2
chr10_-_7699192	0.015		ITIH5	inter-alpha (globulin) inhibitor H5
chr21_-_30510113	0.015	NM_199328	CLDN8	claudin 8
chr17_+_22982372	0.015		LGALS9	lectin, galactoside-binding, soluble, 9
chr12_+_10351683	0.014	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr3_-_58627509	0.014	NM_138805	FAM3D	family with sequence similarity 3, member D
chr3_-_155630197	0.014	NM_001038705	GPR149	G protein-coupled receptor 149
chr4_+_70896236	0.013	NM_001009181 NM_003154	STATH	statherin
chr6_-_50097606	0.013	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chr5_-_169657312	0.013		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_+_40945244	0.013		C7	complement component 7
chr1_+_145841569	0.013	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr11_-_117252541	0.012		FXYD6	FXYD domain containing ion transport regulator 6
chr11_-_57054756	0.012	NM_012456	TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)
chr14_-_20694023	0.012	NM_001004731	OR5AU1	olfactory receptor, family 5, subfamily AU, member 1
chr4_-_91979113	0.012	NM_183049	TMSL3	thymosin-like 3
chr11_+_117680504	0.012	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr20_+_31106797	0.010	NM_182658	C20orf185	chromosome 20 open reading frame 185
chr19_-_59019240	0.010	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chrX_+_36163971	0.010	NM_001098843	CXorf30	chromosome X open reading frame 30
chr11_-_28086277	0.010	NM_031217	KIF18A	kinesin family member 18A
chr16_-_27806978	0.010	NM_144675	GSG1L	GSG1-like
chr11_+_55617328	0.009	NM_001003750	OR8I2	olfactory receptor, family 8, subfamily I, member 2
chrX_-_135783496	0.009
chr2_+_38746742	0.009		GALM	galactose mutarotase (aldose 1-epimerase)
chr7_+_80105907	0.009		CD36	CD36 molecule (thrombospondin receptor)
chr16_-_29514140	0.008
chr5_-_94250357	0.008		MCTP1	multiple C2 domains, transmembrane 1
chr3_+_122769467	0.008	NM_001012659	ARGFX	arginine-fifty homeobox
chr6_-_31954795	0.008	NM_001178044 NM_025257	SLC44A4	solute carrier family 44, member 4
chr12_-_43556220	0.007		NELL2	NEL-like 2 (chicken)
chr7_+_22733290	0.007	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr3_-_14558591	0.007	NM_001080423	GRIP2	glutamate receptor interacting protein 2
chr3_+_153499883	0.007	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr1_+_202033273	0.006	NM_001174108	ZBED6	zinc finger, BED-type containing 6
chr2_+_119416214	0.006	NM_006770	MARCO	macrophage receptor with collagenous structure
chr6_+_101953581	0.006	NM_001166247 NM_021956 NM_175768	GRIK2	glutamate receptor, ionotropic, kainate 2
chr10_+_83627422	0.006	NM_001165973	NRG3	neuregulin 3
chr12_-_16321885	0.006	NM_001170798	SLC15A5	solute carrier family 15, member 5
chr12_+_67366989	0.006	NM_020401	NUP107	nucleoporin 107kDa
chr1_+_84382562	0.005		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr22_+_38652555	0.005		GRAP2	GRB2-related adaptor protein 2
chr7_+_80113570	0.005	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chr10_+_102212787	0.005	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr1_+_165564904	0.004	NM_001198783	POU2F1	POU class 2 homeobox 1
chr1_+_97033103	0.004
chr3_+_115495522	0.004	NM_173799	TIGIT	T cell immunoreceptor with Ig and ITIM domains
chr15_+_43331719	0.004	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr6_+_101953389	0.004		GRIK2	glutamate receptor, ionotropic, kainate 2
chr7_+_72913424	0.004	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr12_+_18305740	0.004	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chr12_-_78853365	0.003	NM_001143885	PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A
chrX_-_84250629	0.003	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr8_+_7340777	0.003	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr1_+_51855133	0.003	NM_024586 NM_148906 NM_148908 NM_148909	OSBPL9	oxysterol binding protein-like 9
chr1_+_84539876	0.003	NM_001134663	SAMD13	sterile alpha motif domain containing 13
chr16_-_18845223	0.003	NM_015092	SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr10_-_45350804	0.002	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr5_+_42792676	0.001	NM_001134848	CCDC152	coiled-coil domain containing 152
chr20_-_45360903	0.001		ZMYND8	zinc finger, MYND-type containing 8
chr1_-_161105174	0.001	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr11_-_117253354	0.001	NM_001164831	FXYD6	FXYD domain containing ion transport regulator 6
chr12_-_18134319	0.001	NM_024730	RERGL	RERG/RAS-like
chr19_+_59941785	0.000	NM_015868	KIR2DS2 KIR2DL3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
13.10	3.71e-03	GO:0032313	regulation of Rab GTPase activity
13.10	3.71e-03	GO:0032483	regulation of Rab protein signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.85	8.78e-04	GO:0005097	Rab GTPase activator activity