Motif ID: EVI1.p2

Z-value: 0.946


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_1708641110.401.2e-01Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_110443881 2.009 NM_177531
 PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr1_-_28376041 1.633 NM_000952
 PTAFR
platelet-activating factor receptor
chr12_+_20739555 1.610 NM_001145945
NM_001145946
NM_001145944
NM_017435
 SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr12_-_242255 1.503 NM_001190997
NM_016615
 SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr2_+_204279442 1.493 NM_006139
 CD28
CD28 molecule
chr6_+_123142559 1.414 FABP7
fatty acid binding protein 7, brain
chr1_+_246591505 1.335 NM_001004696
 OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr19_-_62348381 1.303 NM_052882
 ZIM3
zinc finger, imprinted 3
chr8_-_114518194 1.285 NM_052900
NM_198123
 CSMD3

CUB and Sushi multiple domains 3

chr16_+_28850760 1.278 NM_001178098
NM_001770
 CD19

CD19 molecule

chr7_-_122627235 1.277 NM_022444
 SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr1_+_169171235 1.271 NM_001163629
NM_025063
 C1orf129

chromosome 1 open reading frame 129

chr11_+_59902530 1.227 NM_021201
NM_206938
NM_206939
NM_206940
 MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr15_-_91078307 1.222 FAM174B
family with sequence similarity 174, member B
chr8_+_134272463 1.201 NM_003882
NM_080838
 WISP1

WNT1 inducible signaling pathway protein 1

chr12_-_9804682 1.196 NM_001781
 CD69
CD69 molecule
chr1_+_3658821 1.181 NM_152492
 CCDC27
coiled-coil domain containing 27
chr8_-_27171814 1.175 NM_030795
 STMN4
stathmin-like 4
chrX_-_101581504 1.157 NM_022053
 NXF2
nuclear RNA export factor 2
chr2_-_135498716 1.156 NM_001018046
NM_025052
 YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
15.12 4.08e-02 GO:0043380 regulation of memory T cell differentiation
15.12 4.08e-02 GO:0043382 positive regulation of memory T cell differentiation
15.12 4.08e-02 GO:2000316 regulation of T-helper 17 type immune response
15.12 4.08e-02 GO:2000318 positive regulation of T-helper 17 type immune response
15.12 4.08e-02 GO:2000319 regulation of T-helper 17 cell differentiation
15.12 4.08e-02 GO:2000328 regulation of T-helper 17 cell lineage commitment
15.12 4.08e-02 GO:2000330 positive regulation of T-helper 17 cell lineage commitment
10.08 1.24e-02 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production
3.56 1.90e-24 GO:0007608 sensory perception of smell
3.22 2.69e-21 GO:0007606 sensory perception of chemical stimulus
2.86 1.28e-03 GO:0042445 hormone metabolic process
2.57 1.40e-03 GO:0010817 regulation of hormone levels
2.55 8.26e-03 GO:0050863 regulation of T cell activation
2.53 4.32e-03 GO:0050867 positive regulation of cell activation
2.49 9.03e-03 GO:0002696 positive regulation of leukocyte activation
2.45 6.60e-04 GO:0002694 regulation of leukocyte activation
2.43 6.29e-04 GO:0050865 regulation of cell activation
2.35 1.45e-15 GO:0007600 sensory perception
2.29 1.07e-03 GO:0050778 positive regulation of immune response
2.27 3.18e-02 GO:0051249 regulation of lymphocyte activation

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.65 5.65e-12 GO:0005576 extracellular region
1.59 2.11e-24 GO:0071944 cell periphery
1.59 3.47e-24 GO:0005886 plasma membrane
1.57 1.13e-04 GO:0005887 integral to plasma membrane
1.56 1.01e-04 GO:0031226 intrinsic to plasma membrane
1.55 2.28e-02 GO:0005615 extracellular space
1.49 1.37e-02 GO:0044421 extracellular region part
1.45 1.81e-21 GO:0031224 intrinsic to membrane
1.45 2.20e-20 GO:0016021 integral to membrane
1.37 2.60e-18 GO:0044425 membrane part
1.37 7.93e-04 GO:0044459 plasma membrane part
1.27 1.48e-13 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.65 2.41e-25 GO:0004984 olfactory receptor activity
2.58 1.92e-22 GO:0004930 G-protein coupled receptor activity
2.30 5.27e-25 GO:0004888 transmembrane receptor activity
2.09 4.27e-25 GO:0004872 receptor activity
1.86 1.46e-20 GO:0004871 signal transducer activity
1.86 1.46e-20 GO:0060089 molecular transducer activity