Motif ID: TLX2.p2

Z-value: 1.906


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_745950730.312.4e-01Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_8571988 1.209 NM_030906
 STK33
serine/threonine kinase 33
chr4_-_75938710 1.148 NM_001729
 BTC
betacellulin
chr13_-_46368968 1.117 NM_000621
NM_001165947
 HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr9_+_70509925 1.111 NM_003558
 PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr1_-_245237977 1.019 NM_020394
 ZNF695
zinc finger protein 695
chrX_+_38305634 0.991 NM_004615
 TSPAN7
tetraspanin 7
chr7_-_22363036 0.940 NM_012294
 RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr6_+_167445284 0.917 NM_004367
 CCR6
chemokine (C-C motif) receptor 6
chr1_-_68688219 0.910 NM_000329
 RPE65
retinal pigment epithelium-specific protein 65kDa
chr6_-_26038817 0.887 NM_005835
 SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr1_-_245237925 0.883 ZNF695
zinc finger protein 695
chr3_+_123279439 0.864 NM_006889
 CD86
CD86 molecule
chr12_-_97562532 0.864 NM_153687
NM_201612
NM_201613
 IKBIP


IKBKB interacting protein


chr11_-_22807842 0.860 NM_148893
 SVIP
small VCP/p97-interacting protein
chr2_+_43919606 0.807 NM_022437
 ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr14_-_35859545 0.799 NM_001144891
NM_016586
 MBIP

MAP3K12 binding inhibitory protein 1

chr20_+_42463350 0.796 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42463387 0.771 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_56318415 0.754 RAB22A
RAB22A, member RAS oncogene family
chr18_+_27332024 0.742 NM_001943
 DSG2
desmoglein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.63 4.16e-03 GO:0000278 mitotic cell cycle
1.54 1.35e-02 GO:0022403 cell cycle phase
1.54 1.41e-02 GO:0002682 regulation of immune system process
1.37 4.01e-02 GO:0002376 immune system process
1.12 2.14e-02 GO:0065007 biological regulation
1.12 3.18e-02 GO:0008152 metabolic process
1.12 3.82e-02 GO:0050789 regulation of biological process
1.08 4.09e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
5.25 1.58e-02 GO:0042613 MHC class II protein complex
1.38 1.57e-03 GO:0005654 nucleoplasm
1.32 2.39e-05 GO:0031974 membrane-enclosed lumen
1.32 3.10e-05 GO:0043233 organelle lumen
1.32 2.27e-04 GO:0005829 cytosol
1.31 1.29e-04 GO:0070013 intracellular organelle lumen
1.31 2.00e-03 GO:0031981 nuclear lumen
1.27 5.10e-03 GO:0044428 nuclear part
1.25 6.78e-04 GO:0043234 protein complex
1.24 7.05e-05 GO:0032991 macromolecular complex
1.21 3.10e-02 GO:0043228 non-membrane-bounded organelle
1.21 3.10e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.20 1.72e-06 GO:0044422 organelle part
1.20 1.95e-06 GO:0044446 intracellular organelle part
1.16 2.02e-04 GO:0044444 cytoplasmic part
1.15 5.67e-07 GO:0005737 cytoplasm
1.11 1.40e-04 GO:0043229 intracellular organelle
1.11 1.59e-03 GO:0043227 membrane-bounded organelle
1.11 1.60e-03 GO:0043231 intracellular membrane-bounded organelle
1.10 1.69e-04 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.13 2.84e-03 GO:0005515 protein binding