Motif ID: NANOG.p2

Z-value: 0.806


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_78332610.341.9e-01Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_77575276 1.790 NM_020859
 SHROOM3
shroom family member 3
chr18_+_74841262 1.120 NM_171999
 SALL3
sal-like 3 (Drosophila)
chr3_-_74652952 1.025 NM_020872
 CNTN3
contactin 3 (plasmacytoma associated)
chr1_-_150653351 0.991 NM_016190
 CRNN
cornulin
chr20_-_33489383 0.939 NM_000557
 GDF5
growth differentiation factor 5
chr4_-_138673014 0.929 PCDH18
protocadherin 18
chr3_-_57209319 0.902 NM_003865
 HESX1
HESX homeobox 1
chr12_-_51114372 0.900 NM_004693
 KRT75
keratin 75
chr6_-_31215089 0.896 NM_014069
 PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_+_161040343 0.889 NM_001197109
 SCHIP1
schwannomin interacting protein 1
chr11_+_123986661 0.867 NM_052959
 PANX3
pannexin 3
chr2_+_17861266 0.858 NM_001105569
 MSGN1
mesogenin 1
chr17_-_36403910 0.757 NM_033185
 KRTAP3-3
keratin associated protein 3-3
chr14_-_94306104 0.739 NM_173849
 GSC
goosecoid homeobox
chr1_+_168898898 0.716 PRRX1
paired related homeobox 1
chr11_-_2149591 0.692 NM_000360
NM_199292
NM_199293
 TH


tyrosine hydroxylase


chr7_+_129693938 0.688 NM_001869
 CPA2
carboxypeptidase A2 (pancreatic)
chr1_-_154484341 0.683 NM_198406
NM_024897
 PAQR6

progestin and adipoQ receptor family member VI

chr15_+_56217686 0.663 NM_020980
 AQP9
aquaporin 9
chr11_-_27637771 0.636 NM_001143816
NM_170735
 BDNF

brain-derived neurotrophic factor


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
15.45 1.03e-02 GO:0051155 positive regulation of striated muscle cell differentiation
6.18 5.91e-03 GO:0051149 positive regulation of muscle cell differentiation
4.56 1.87e-02 GO:0042472 inner ear morphogenesis
4.56 1.87e-02 GO:0051147 regulation of muscle cell differentiation
4.17 2.23e-02 GO:0042471 ear morphogenesis
4.09 7.14e-05 GO:0001503 ossification
3.63 1.22e-05 GO:0007517 muscle organ development
3.15 1.77e-02 GO:0048562 embryonic organ morphogenesis
3.00 2.24e-02 GO:0030900 forebrain development
2.99 5.17e-03 GO:0008544 epidermis development
2.77 1.39e-03 GO:0061061 muscle structure development
2.75 6.86e-04 GO:0016337 cell-cell adhesion
2.63 3.06e-02 GO:0040007 growth
2.53 1.37e-04 GO:0007608 sensory perception of smell
2.51 5.01e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.44 4.16e-03 GO:0007420 brain development
2.38 3.69e-04 GO:0007606 sensory perception of chemical stimulus
2.35 2.30e-08 GO:0007600 sensory perception
2.35 4.78e-02 GO:0060284 regulation of cell development
2.32 1.74e-02 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
8.83 4.45e-02 GO:0042613 MHC class II protein complex
5.25 4.51e-06 GO:0045095 keratin filament
5.15 5.03e-03 GO:0034774 secretory granule lumen
4.94 7.35e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
4.75 1.05e-02 GO:0031983 vesicle lumen
4.73 2.66e-02 GO:0031093 platelet alpha granule lumen
4.26 2.79e-02 GO:0031091 platelet alpha granule
3.40 7.72e-05 GO:0005882 intermediate filament
3.07 2.87e-04 GO:0045111 intermediate filament cytoskeleton
2.59 2.38e-04 GO:0005578 proteinaceous extracellular matrix
2.47 1.71e-04 GO:0031012 extracellular matrix
1.72 2.20e-03 GO:0044421 extracellular region part
1.66 6.32e-07 GO:0005576 extracellular region
1.51 4.79e-10 GO:0005886 plasma membrane
1.48 2.25e-09 GO:0071944 cell periphery
1.40 2.37e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.65 7.81e-06 GO:0004984 olfactory receptor activity
2.57 2.91e-02 GO:0000975 regulatory region DNA binding
2.57 2.91e-02 GO:0001067 regulatory region nucleic acid binding
2.57 2.91e-02 GO:0044212 transcription regulatory region DNA binding
2.09 1.28e-04 GO:0005509 calcium ion binding
2.06 1.55e-04 GO:0043565 sequence-specific DNA binding
2.04 1.33e-05 GO:0004930 G-protein coupled receptor activity
1.85 1.74e-04 GO:0001071 nucleic acid binding transcription factor activity
1.85 1.74e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.80 1.90e-05 GO:0004888 transmembrane receptor activity
1.75 1.06e-06 GO:0004872 receptor activity
1.69 9.67e-03 GO:0030528 transcription regulator activity
1.63 4.07e-06 GO:0004871 signal transducer activity
1.63 4.07e-06 GO:0060089 molecular transducer activity