Motif ID: NANOG.p2

Z-value: 0.806


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_78332610.341.9e-01Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_77575276 1.790 NM_020859
SHROOM3
shroom family member 3
chr18_+_74841262 1.120 NM_171999
SALL3
sal-like 3 (Drosophila)
chr3_-_74652952 1.025 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr1_-_150653351 0.991 NM_016190
CRNN
cornulin
chr20_-_33489383 0.939 NM_000557
GDF5
growth differentiation factor 5
chr4_-_138673014 0.929 PCDH18
protocadherin 18
chr3_-_57209319 0.902 NM_003865
HESX1
HESX homeobox 1
chr12_-_51114372 0.900 NM_004693
KRT75
keratin 75
chr6_-_31215089 0.896 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_+_161040343 0.889 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr11_+_123986661 0.867 NM_052959
PANX3
pannexin 3
chr2_+_17861266 0.858 NM_001105569
MSGN1
mesogenin 1
chr17_-_36403910 0.757 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr14_-_94306104 0.739 NM_173849
GSC
goosecoid homeobox
chr1_+_168898898 0.716 PRRX1
paired related homeobox 1
chr11_-_2149591 0.692 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr7_+_129693938 0.688 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr1_-_154484341 0.683 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr15_+_56217686 0.663 NM_020980
AQP9
aquaporin 9
chr11_-_27637771 0.636 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr1_-_116185215 0.633 NM_005599
NHLH2
nescient helix loop helix 2
chr7_-_13992351 0.627 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr17_-_36456949 0.624 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr21_-_30836051 0.622 NM_181612
KRTAP19-6
keratin associated protein 19-6
chr12_-_52016270 0.606 NM_001173467
SP7
Sp7 transcription factor
chr14_-_56342097 0.603 NM_172337
OTX2
orthodenticle homeobox 2
chr11_+_4427100 0.584 NM_001005172
OR52K2
olfactory receptor, family 52, subfamily K, member 2
chr8_-_40874485 0.575 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chrX_+_66705407 0.574 NM_001011645
AR
androgen receptor
chr7_+_141054621 0.572 NM_001105558
WEE2
WEE1 homolog 2 (S. pombe)
chr14_+_104117100 0.562 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr20_+_58004811 0.559 NM_021810
CDH26
cadherin 26
chr20_+_2224612 0.554 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr16_-_79811475 0.545 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chr5_+_140790141 0.538 PCDHGA12
protocadherin gamma subfamily A, 12
chr3_+_89239494 0.536 EPHA3
EPH receptor A3
chr22_+_44828338 0.535


chr7_-_13996166 0.533 NM_001163147
NM_004956
ETV1

ets variant 1

chr2_+_121271336 0.522 NM_005270
GLI2
GLI family zinc finger 2
chr12_-_6103945 0.521 NM_000552
VWF
von Willebrand factor
chr12_-_51086330 0.506 NM_033033
KRT82
keratin 82
chr7_+_129771865 0.504 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr7_-_121731721 0.503 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr1_-_50661716 0.501 NM_032110
DMRTA2
DMRT-like family A2
chr4_-_138673078 0.500 NM_019035
PCDH18
protocadherin 18
chr5_-_22248630 0.497 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr2_+_157822355 0.496 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr17_-_19290745 0.496


chr5_-_168204430 0.495


chr3_+_161040439 0.479 SCHIP1
schwannomin interacting protein 1
chr3_-_145049853 0.478 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr8_+_55691179 0.474 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr1_+_74473672 0.472 NM_015978
TNNI3K
TNNI3 interacting kinase
chr3_+_130730171 0.468 NM_000539
RHO
rhodopsin
chr4_+_78651929 0.461 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr3_+_35697432 0.459 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr8_+_67201684 0.450 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr4_-_41445693 0.444 NM_003924
PHOX2B
paired-like homeobox 2b
chr6_+_44076281 0.442 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr19_+_7874701 0.441 MAP2K7
mitogen-activated protein kinase kinase 7
chr2_-_110665188 0.432 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr21_+_43024936 0.430 PDE9A
phosphodiesterase 9A
chr13_+_23042722 0.428 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chrX_+_41191630 0.426 NM_022567
NYX
nyctalopin
chr6_+_49575629 0.423 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr9_+_108665168 0.423 NM_021224
ZNF462
zinc finger protein 462
chr5_+_140703784 0.421 NM_018916
NM_032011
PCDHGA3

protocadherin gamma subfamily A, 3

chr15_+_100175888 0.413 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chr1_+_207944807 0.411 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr17_-_36594652 0.408 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr5_+_169713458 0.408 NM_001034838
KCNIP1
Kv channel interacting protein 1
chr7_-_25234582 0.407 NM_022150
NPVF
neuropeptide VF precursor
chr19_+_50663089 0.407 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr11_-_69343128 0.406 NM_005247
FGF3
fibroblast growth factor 3
chr6_-_112682401 0.406 LAMA4
laminin, alpha 4
chr1_+_109884016 0.394 NM_031936
GPR61
G protein-coupled receptor 61
chr5_-_35974493 0.394 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr11_-_57173823 0.392 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr9_+_135491305 0.389 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr2_+_27155197 0.386 EMILIN1
elastin microfibril interfacer 1
chr3_-_113842652 0.382 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr5_+_140790310 0.381 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr8_+_32698892 0.380 NM_001159996
NRG1
neuregulin 1
chr13_-_31784088 0.380 NM_001136571
ZAR1L
zygote arrest 1-like
chr9_-_132759045 0.371 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr6_-_169392771 0.369


chr5_+_140790365 0.368 PCDHGA12
protocadherin gamma subfamily A, 12
chr1_+_180836050 0.367


chr6_-_112682573 0.366 LAMA4
laminin, alpha 4
chr6_-_112682459 0.365 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr13_+_100902942 0.357 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_+_150376537 0.357 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr17_-_36418869 0.356 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr10_-_105835525 0.356 COL17A1
collagen, type XVII, alpha 1
chr5_+_140848905 0.355 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr10_-_13789628 0.354 FRMD4A
FERM domain containing 4A
chrX_-_21586337 0.353 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr6_+_34314545 0.352 NM_145905
HMGA1
high mobility group AT-hook 1
chr4_-_26100986 0.350 NM_000730
CCKAR
cholecystokinin A receptor
chr3_-_116272911 0.346 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_102522093 0.345 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr22_-_39189369 0.343 MKL1
megakaryoblastic leukemia (translocation) 1
chr3_+_16191159 0.343 NM_054110
GALNTL2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr19_+_3713650 0.337 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr2_+_225973845 0.335 NM_020864
KIAA1486
KIAA1486
chr21_-_30460841 0.333 NM_012131
CLDN17
claudin 17
chr14_-_104330982 0.333 NM_005163
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr20_+_43691797 0.332 NM_080753
WFDC10A
WAP four-disulfide core domain 10A
chr12_-_90100710 0.327 DCN
decorin
chr5_+_170668892 0.327 NM_021025
TLX3
T-cell leukemia homeobox 3
chr14_+_51025604 0.322 NM_001042481
FRMD6
FERM domain containing 6
chr6_-_39801088 0.320 NM_145027
KIF6
kinesin family member 6
chr17_-_9635325 0.320 NM_001105571
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr10_-_93659164 0.319 NM_152429
FGFBP3
fibroblast growth factor binding protein 3
chr6_+_134800533 0.316 LOC154092
hypothetical LOC154092
chr3_-_121445831 0.314 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chrX_+_37777730 0.313 NM_001163334
SYTL5
synaptotagmin-like 5
chr4_+_110968594 0.313 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr2_-_27967458 0.312 LOC100302650
hypothetical LOC100302650
chr8_-_134156353 0.310 SLA
Src-like-adaptor
chr2_+_210152609 0.308 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr2_-_40510923 0.308 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr12_-_51332214 0.307 NM_000423
KRT2
keratin 2
chr5_+_140790510 0.304 PCDHGA12
protocadherin gamma subfamily A, 12
chr8_-_142333339 0.301 SLC45A4
solute carrier family 45, member 4
chr3_+_150675117 0.300 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr8_-_93176819 0.300 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_41445479 0.299 PHOX2B
paired-like homeobox 2b
chr5_+_140494971 0.299 NM_015669
PCDHB5
protocadherin beta 5
chr5_+_140460240 0.298 NM_018937
PCDHB3
protocadherin beta 3
chr8_-_20084892 0.297 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr17_-_39094787 0.296 NM_001040002
MEOX1
mesenchyme homeobox 1
chr10_+_118073929 0.296 NM_198515
C10orf96
chromosome 10 open reading frame 96
chr2_+_161981138 0.294 TBR1
T-box, brain, 1
chr9_+_6205804 0.290 IL33
interleukin 33
chr7_+_113842470 0.289 FOXP2
forkhead box P2
chr2_-_224175339 0.289 SCG2
secretogranin II
chr11_-_83071084 0.287 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_207823667 0.287 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr12_-_89922888 0.285 NM_004950
EPYC
epiphycan
chr7_-_41709191 0.283 NM_002192
INHBA
inhibin, beta A
chr12_+_111713931 0.282 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr8_-_93176618 0.282 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr5_+_140509803 0.280 NM_018939
PCDHB6
protocadherin beta 6
chr1_-_155336223 0.278 NM_001004341
ETV3L
ets variant 3-like
chr7_+_143437539 0.276 NM_001005480
OR2A2
olfactory receptor, family 2, subfamily A, member 2
chr13_+_108079570 0.275 NM_001198950
MYO16
myosin XVI
chr2_+_95326753 0.275 NM_013434
KCNIP3
Kv channel interacting protein 3, calsenilin
chr2_+_96269703 0.272 NM_001037228
LOC285033
hypothetical protein LOC285033
chr17_-_24972471 0.272 NM_032854
CORO6
coronin 6
chr8_-_134156437 0.271 SLA
Src-like-adaptor
chr3_-_21767819 0.270 NM_024697
ZNF385D
zinc finger protein 385D
chr15_-_91078307 0.269 FAM174B
family with sequence similarity 174, member B
chr7_-_5429702 0.269 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr11_-_104421240 0.269 NM_001017534
NM_052889
CARD16

CASP1
caspase recruitment domain family, member 16

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr8_+_24354387 0.267 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr12_+_111714096 0.264 RPH3A
rabphilin 3A homolog (mouse)
chr10_+_26545241 0.263 NM_000818
NM_001134366
GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

chr1_-_32036802 0.262 SPOCD1
SPOC domain containing 1
chr2_-_224175386 0.261 NM_003469
SCG2
secretogranin II
chr14_+_75907442 0.259 NM_004452
ESRRB
estrogen-related receptor beta
chr14_+_77939845 0.257 NM_004796
NRXN3
neurexin 3
chr11_-_128217550 0.257 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr1_+_151456683 0.255 NM_001195571
PRR9
proline rich 9
chr1_-_158098962 0.255 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr11_+_63775567 0.250 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr5_+_176744037 0.246 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr2_+_1396239 0.245 NM_000547
NM_175719
TPO

thyroid peroxidase

chrX_+_50044279 0.245 NM_033031
NM_033670
CCNB3

cyclin B3

chr5_+_31229609 0.245 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr11_-_57792206 0.241 NM_207374
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr1_-_53380709 0.240 NM_006671
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr2_+_113542017 0.240 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chrX_-_108611940 0.238 NM_001522
GUCY2F
guanylate cyclase 2F, retinal
chr6_-_32605898 0.237 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr5_-_24535386 0.237 NM_001190450
CDH10
cadherin 10, type 2 (T2-cadherin)
chr12_+_25096472 0.236 NM_006152
LRMP
lymphoid-restricted membrane protein
chr9_-_112381593 0.236 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chrX_+_102918409 0.235 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr6_+_84619703 0.234 NM_001009994
RIPPLY2
ripply2 homolog (zebrafish)
chr2_+_161980865 0.234 NM_006593
TBR1
T-box, brain, 1
chr17_+_39990124 0.233 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr6_+_29902734 0.233 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr20_+_42463279 0.232 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr16_-_66075216 0.231 NM_001138
AGRP
agouti related protein homolog (mouse)
chr19_+_59333287 0.231 CNOT3
CCR4-NOT transcription complex, subunit 3
chrX_+_48978870 0.228 NM_014008
CCDC22
coiled-coil domain containing 22
chr17_-_36528113 0.227 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr12_-_90100733 0.225 NM_001920
DCN
decorin
chr3_+_69895310 0.225 NM_001184967
MITF
microphthalmia-associated transcription factor
chr13_+_48178620 0.224 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr7_+_94135384 0.224 PEG10
paternally expressed 10
chr12_+_50342814 0.223 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr1_-_230717850 0.223 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr12_-_107551783 0.222 NM_003006
SELPLG
selectin P ligand
chr4_+_114190233 0.221 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr12_+_25096755 0.221 LRMP
lymphoid-restricted membrane protein
chr4_-_174687931 0.220 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chrX_+_135058402 0.220 NM_001159700
FHL1
four and a half LIM domains 1
chr7_-_99555399 0.219 NM_001190415
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.61 6.00e-19 GO:0032501 multicellular organismal process
1.98 1.07e-10 GO:0003008 system process
1.93 1.16e-10 GO:0048513 organ development
1.66 1.44e-10 GO:0048856 anatomical structure development
1.71 1.93e-10 GO:0048731 system development
1.60 8.77e-10 GO:0007275 multicellular organismal development
2.05 2.44e-09 GO:0050877 neurological system process
1.55 2.66e-09 GO:0032502 developmental process
2.35 2.30e-08 GO:0007600 sensory perception
3.63 1.22e-05 GO:0007517 muscle organ development
2.10 1.67e-05 GO:0009888 tissue development
4.09 7.14e-05 GO:0001503 ossification
1.75 9.91e-05 GO:0007399 nervous system development
2.17 1.30e-04 GO:0045595 regulation of cell differentiation
2.53 1.37e-04 GO:0007608 sensory perception of smell
1.59 3.30e-04 GO:0030154 cell differentiation
2.38 3.69e-04 GO:0007606 sensory perception of chemical stimulus
2.51 5.01e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.75 6.86e-04 GO:0016337 cell-cell adhesion
1.93 6.96e-04 GO:0050793 regulation of developmental process
1.56 8.13e-04 GO:0048869 cellular developmental process
1.88 8.57e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.77 1.39e-03 GO:0061061 muscle structure development
2.10 3.37e-03 GO:0009887 organ morphogenesis
1.64 4.01e-03 GO:0009653 anatomical structure morphogenesis
2.19 4.09e-03 GO:0007417 central nervous system development
1.95 4.10e-03 GO:0007155 cell adhesion
1.95 4.10e-03 GO:0022610 biological adhesion
2.44 4.16e-03 GO:0007420 brain development
2.99 5.17e-03 GO:0008544 epidermis development
2.15 5.18e-03 GO:0045892 negative regulation of transcription, DNA-dependent
6.18 5.91e-03 GO:0051149 positive regulation of muscle cell differentiation
2.24 8.27e-03 GO:0051094 positive regulation of developmental process
2.11 8.67e-03 GO:0051253 negative regulation of RNA metabolic process
2.02 8.91e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
15.45 1.03e-02 GO:0051155 positive regulation of striated muscle cell differentiation
2.17 1.19e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.02 1.20e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.98 1.32e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.93 1.55e-02 GO:0009790 embryo development
1.99 1.66e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.32 1.74e-02 GO:0048598 embryonic morphogenesis
3.15 1.77e-02 GO:0048562 embryonic organ morphogenesis
1.94 1.83e-02 GO:0031327 negative regulation of cellular biosynthetic process
4.56 1.87e-02 GO:0042472 inner ear morphogenesis
4.56 1.87e-02 GO:0051147 regulation of muscle cell differentiation
2.00 1.94e-02 GO:0010629 negative regulation of gene expression
4.17 2.23e-02 GO:0042471 ear morphogenesis
3.00 2.24e-02 GO:0030900 forebrain development
1.86 2.90e-02 GO:2000026 regulation of multicellular organismal development
2.63 3.06e-02 GO:0040007 growth
1.90 3.17e-02 GO:0009890 negative regulation of biosynthetic process
1.79 3.40e-02 GO:0048699 generation of neurons
1.91 3.43e-02 GO:0010628 positive regulation of gene expression
2.35 4.78e-02 GO:0060284 regulation of cell development
1.75 4.81e-02 GO:0022008 neurogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 4.79e-10 GO:0005886 plasma membrane
1.48 2.25e-09 GO:0071944 cell periphery
1.66 6.32e-07 GO:0005576 extracellular region
5.25 4.51e-06 GO:0045095 keratin filament
3.40 7.72e-05 GO:0005882 intermediate filament
2.47 1.71e-04 GO:0031012 extracellular matrix
2.59 2.38e-04 GO:0005578 proteinaceous extracellular matrix
3.07 2.87e-04 GO:0045111 intermediate filament cytoskeleton
1.72 2.20e-03 GO:0044421 extracellular region part
5.15 5.03e-03 GO:0034774 secretory granule lumen
4.94 7.35e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
4.75 1.05e-02 GO:0031983 vesicle lumen
1.40 2.37e-02 GO:0044459 plasma membrane part
4.73 2.66e-02 GO:0031093 platelet alpha granule lumen
4.26 2.79e-02 GO:0031091 platelet alpha granule
8.83 4.45e-02 GO:0042613 MHC class II protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.75 1.06e-06 GO:0004872 receptor activity
1.63 4.07e-06 GO:0004871 signal transducer activity
1.63 4.07e-06 GO:0060089 molecular transducer activity
2.65 7.81e-06 GO:0004984 olfactory receptor activity
2.04 1.33e-05 GO:0004930 G-protein coupled receptor activity
1.80 1.90e-05 GO:0004888 transmembrane receptor activity
2.09 1.28e-04 GO:0005509 calcium ion binding
2.06 1.55e-04 GO:0043565 sequence-specific DNA binding
1.85 1.74e-04 GO:0001071 nucleic acid binding transcription factor activity
1.85 1.74e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.69 9.67e-03 GO:0030528 transcription regulator activity
2.57 2.91e-02 GO:0000975 regulatory region DNA binding
2.57 2.91e-02 GO:0001067 regulatory region nucleic acid binding
2.57 2.91e-02 GO:0044212 transcription regulatory region DNA binding